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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0875 | - | - | 100% (357) | PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE MURB (UDP-N-ACETYLMURAMATE DEHYDROGENASE) |
M. thermoresistible (build 8) | TH_3285 | - | 3e-05 | 100.00% (20) | PUTATIVE - |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0492 | murB | 1e-135 | 69.21% (367) | UDP-N-acetylenolpyruvoylglucosamine reductase |
M. gilvum PYR-GCK | Mflv_0090 | murB | 1e-147 | 76.27% (354) | UDP-N-acetylenolpyruvoylglucosamine reductase |
M. tuberculosis H37Rv | Rv0482 | murB | 1e-135 | 69.21% (367) | UDP-N-acetylenolpyruvoylglucosamine reductase |
M. leprae Br4923 | MLBr_02447 | murB | 1e-130 | 65.21% (365) | UDP-N-acetylenolpyruvoylglucosamine reductase |
M. abscessus ATCC 19977 | MAB_4066c | - | 1e-114 | 61.97% (355) | UDP-N-acetylenolpyruvoylglucosamine reductase MurB |
M. marinum M | MMAR_0808 | murB | 1e-132 | 68.22% (365) | UDP-N-acetylenolpyruvoylglucosamine reductase MurB |
M. avium 104 | MAV_4668 | murB | 1e-133 | 66.67% (369) | UDP-N-acetylenolpyruvoylglucosamine reductase |
M. smegmatis MC2 155 | MSMEG_0928 | murB | 1e-153 | 76.18% (361) | UDP-N-acetylenolpyruvoylglucosamine reductase |
M. ulcerans Agy99 | MUL_4552 | murB | 1e-130 | 67.40% (365) | UDP-N-acetylenolpyruvoylglucosamine reductase |
M. vanbaalenii PYR-1 | Mvan_0823 | murB | 1e-146 | 75.93% (349) | UDP-N-acetylenolpyruvoylglucosamine reductase |
CLUSTAL 2.0.9 multiple sequence alignment TH_0875|M.thermoresistible__bu -------VVGSRVAGVPVAEGVPLAPLTTLRVGPVARRLIECTATDQVIG MSMEG_0928|M.smegmatis_MC2_155 -------MASSHVAGVEIAEAVPLAPLTTLRIGPVARRMLTCTSTEQLIG Mflv_0090|M.gilvum_PYR-GCK -------MGTSLLGGVPVAENVPLAPLTTLRVGPVARRLVTCVTTDQIVD Mvan_0823|M.vanbaalenii_PYR-1 -----------MSGGVPFAEQVPLAPLTTLRVGPVARRLITCVATEQIGP Mb0492|M.bovis_AF2122/97 ---MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVA Rv0482|M.tuberculosis_H37Rv ---MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVA MLBr_02447|M.leprae_Br4923 ---MKRSAVGSFFAGAHVAEAVSLAPLTTLRVGPVAQRVITCASTEQVVD MAV_4668|M.avium_104 ---MKSSGAGAAFAGASVADAVPLAPLTTLRVGPTARRLITCASSEQVIA MMAR_0808|M.marinum_M ---MKRRDVGSLFAGARVAESVPLAPLTTLRVGPVARTLVTCDTTDQVVG MUL_4552|M.ulcerans_Agy99 ---MKRRDVGSLFAGARVAESVPLAPLTTLRVGPVARTLVTCDTTDQVVG MAB_4066c|M.abscessus_ATCC_199 MGLARTTRAEIEDLGAVVTEGAALAPLTTLRLGPVAATLIRCESTRQVTG *. .:: ..********:** * :: * :: *: TH_0875|M.thermoresistible__bu VLRVLDADRTG----PMLVLAGGSNVVLADDLTDLTVVRLANDRISVDGH MSMEG_0928|M.smegmatis_MC2_155 VLRALTADDE-----PLLILAGGSNVVLADDLTDLTVVRIANTEITVDGD Mflv_0090|M.gilvum_PYR-GCK AVMAAGPEAL--------ILAGGSNVVLAGDAADLTVVRLANTRISVDGD Mvan_0823|M.vanbaalenii_PYR-1 AVRAAGPDAL--------ILAGGSNVVIADDLADLTVVRLANTGIVVDGA Mb0492|M.bovis_AF2122/97 ALRHLDS-AAKTGADRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGN Rv0482|M.tuberculosis_H37Rv ALRHLDS-AAKTGADRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGN MLBr_02447|M.leprae_Br4923 VIRQLDAPAGGRGAGPLLIFAGGSNLVIADTLADLTAVRLANAGITIDGN MAV_4668|M.avium_104 TLRRLDTERLAGQRDPVLVFAGGSNLVISDALSDLTAVRLANDGITVEGN MMAR_0808|M.marinum_M VLRELDDRARNGDCGPVLVFAGGSNVVIGDALADLTVVRVANDRVTIDGN MUL_4552|M.ulcerans_Agy99 VLRELDDRARNGDCGPVLVFAGGSNVVIGDALADLTVVRVANDRVTVDGN MAB_4066c|M.abscessus_ATCC_199 TLAALDG-------HPALLLAGGSNVVLADDLADVTAVHIAAAGVTVDGS .: ::*****:*:. :*:*.*::* : ::* TH_0875|M.thermoresistible__bu LVRAEAGALWDDVVVTSLAHGLGGLECLSGIPGSAGATPVQNVGAYGAEV MSMEG_0928|M.smegmatis_MC2_155 RVRAEAGALWDDVVVTSLAHGLGGLECLSGIPGSAGATPVQNVGAYGAEV Mflv_0090|M.gilvum_PYR-GCK VVRAEAGAGWDDVVAASLAHGLGGLECLSGIPGSAGATPVQNVGAYGAEV Mvan_0823|M.vanbaalenii_PYR-1 VVRAEAGAVWDDVVAASLTQGLGGLECLSGIPGSAGATPVQNVGAYGAEV Mb0492|M.bovis_AF2122/97 LVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEV Rv0482|M.tuberculosis_H37Rv LVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEV MLBr_02447|M.leprae_Br4923 LVRAEAGAVWDDVVVRAIEHGLGGLECLSGIPGSAGATPVQNVGAYGAEV MAV_4668|M.avium_104 LVRAQAGAVWDDVVLTAIEHGLGGLECLSGIPGSAGATPIQNVGAYGAEV MMAR_0808|M.marinum_M LVRAEAGAVWDEVVVAAIERGLGGLECLSGIPGSAGATPVQNVGAYGVEV MUL_4552|M.ulcerans_Agy99 LVRAEAGTVWDEVVVATIERGLGGLECLSGIPGSAGATPVQNVGAYGVEV MAB_4066c|M.abscessus_ATCC_199 LLRAEAGANWDEVVALSLRAGLGGLECLSGIPGTAGATPVQNVGAYGVEV :**:**: :*:** :: *************:*****:*******.** TH_0875|M.thermoresistible__bu ADTIRRVRLHDRRTGEDRWVAPEYLRFGYRSSILKHSD------TVVVLE MSMEG_0928|M.smegmatis_MC2_155 ADTITRVRLLDRRTGEDRWATTEELRFGYRTSVLKHSD------AVIVLE Mflv_0090|M.gilvum_PYR-GCK ADTIRRVRLLERGTGSVRWVSPEFLRFGYRTSVLKHSS------QWVVLE Mvan_0823|M.vanbaalenii_PYR-1 SDTIRRVRLLDRSTGDDRWVNPDFLQFGYRTSILKKSS------AWVVLE Mb0492|M.bovis_AF2122/97 SDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHAD--GLAVPTVVLE Rv0482|M.tuberculosis_H37Rv SDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHAD--GLAVPTVVLE MLBr_02447|M.leprae_Br4923 SDTITRVRLLERSSGSVRWVSACELRFGYRTSVFKQADPSGSQPPAVVLE MAV_4668|M.avium_104 SDTLTRVRVLDRGSGQVRWVPGTELEFGYRTSVFKRRADDGLEIPSVVLE MMAR_0808|M.marinum_M SDVITRVRLLDRSTGEVSWVPAADLSFGYRTSVLKQAD--GLALPAVVLE MUL_4552|M.ulcerans_Agy99 SDVITRVRLLDRSTGDVSWVPAADLSFGYRTSVLKQAE--GLALPAVVLE MAB_4066c|M.abscessus_ATCC_199 SSLLRRVRVLNRETGRVRWYGPDELRFGYRTSILKGTS------ARVVLE :. : ***: :* :* * * ****:*::* :*** TH_0875|M.thermoresistible__bu VEFALDPAGRSAPIRYAELARTLDVATGERTDPARVREAVLALRAGKGML MSMEG_0928|M.smegmatis_MC2_155 VEFGLDAAGRSAPVRYRELATALGVEPGERTDPLRVRDAVLRLRTGKGMV Mflv_0090|M.gilvum_PYR-GCK VEFGLDAAGHSAPVRYRELATELAVEQGERTDPQRVRAAVLELRARKGMV Mvan_0823|M.vanbaalenii_PYR-1 VEFALDASGRSAPLRYGELAAELNAEPGERVDPAQVRAAVLSLRARKGMV Mb0492|M.bovis_AF2122/97 VEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMV Rv0482|M.tuberculosis_H37Rv VEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMV MLBr_02447|M.leprae_Br4923 VEFKLDASGQSAPLHYGELVATLDATSGQRANPHAVREAVLALRVRKGMV MAV_4668|M.avium_104 VEFALDASGRSAPVRYGELAAELEVPVGERADPRAVREAVLALRARKGMV MMAR_0808|M.marinum_M VEFALDASGRSAPLRYGELTAALGMNSGERGEPRAVRDAVLALRARKGMV MUL_4552|M.ulcerans_Agy99 VEFALDASGRSAPLRYGELTAALGMNSGERGEPRAVRDAVLALRTRKGMV MAB_4066c|M.abscessus_ATCC_199 VEFGLSTDGLSAPIRYPELAKELGVAQGDRTDASAVREAVLGLRRRKGMV *** *.. * ***::* ** * *:* :. ** *** ** ***: TH_0875|M.thermoresistible__bu TS-AATVDDHDTWSVGSFFTNPVVSTAEFERIR----DSAPGP---VPNY MSMEG_0928|M.smegmatis_MC2_155 VDPDPDHPDHDTWSVGSFFTNPVVTHADFERVERIARDAGAGP---VPNY Mflv_0090|M.gilvum_PYR-GCK LD----AADHDTWSVGSFFTNPVVSRAEFERIA----ATVGSA---VPNY Mvan_0823|M.vanbaalenii_PYR-1 LD----AADHDTWSVGSFFTNPVVSRAEFDQLA----ASVDGP---VPNY Mb0492|M.bovis_AF2122/97 LD----PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP---VPHY Rv0482|M.tuberculosis_H37Rv LD----PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP---VPHY MLBr_02447|M.leprae_Br4923 LD----AADHDTWSVGSFFTNPVVAPDVYRQLA----KMVDGP---VPHY MAV_4668|M.avium_104 LD----AADHDTWSVGSFFTNPVVAPDVYERLAG----SVDGP---VPHY MMAR_0808|M.marinum_M LD----AADHDTWSVGSFFTNPVVAPEIYERLAA----QTGES---VPHY MUL_4552|M.ulcerans_Agy99 LD----AADHDTWSVGSFFTNPVVAPEIYERLAA----QTGES---VPHY MAB_4066c|M.abscessus_ATCC_199 LD----ESDRDTWSVGSFFTNPVVAEGDVDGVRAR-VHEHLGPGVVMPLY . *:**************: : . :* * TH_0875|M.thermoresistible__bu PAPDGVKLAAAWLVERAGFGRGY----PGA-GAPVRLSTKHALALTNRGN MSMEG_0928|M.smegmatis_MC2_155 PAPDGVKLAAGWLVERAGFGKGY----PGE-GARARLSTKHALALTNRGQ Mflv_0090|M.gilvum_PYR-GCK PAEDGVKLAAGWLVEQAGFGKGY----PGA-DAPARLSTKHALALTNRGT Mvan_0823|M.vanbaalenii_PYR-1 PAPDGVKLAAGWLVERAGFGKGY----PDD-EAPARLSTKHALALTNRGT Mb0492|M.bovis_AF2122/97 PAPDGVKLAAGWLVERAGFGKGY----PDAGAAPCRLSTKHALALTNRGG Rv0482|M.tuberculosis_H37Rv PAPDGVKLAAGWLVERAGFGKGY----PDAGAAPCRLSTKHALALTNRGG MLBr_02447|M.leprae_Br4923 PAQDGVKLAAGWLVERAGFGKGY----PDG-AAPCRLSTKHVLALTNRGA MAV_4668|M.avium_104 PAPGGVKLAAGWLVERAGFGKGYPVPDPGGPEAPCRLSTKHALALTNRGT MMAR_0808|M.marinum_M PAPDGVKLAAGWLLERAGFGKGY----PGDPHARCRLSSKHALALTNRGG MUL_4552|M.ulcerans_Agy99 PAPDGVKLAAGWLLERAGFGKGY----PGDPHARCRLSSKHALALTNRGG MAB_4066c|M.abscessus_ATCC_199 SAQHGVKLSAGWLVERAGFDKGY----PGE-RSAVRVSTKHALALTHRGG .* ****:*.**:*:***.:** *. : *:*:**.****:** TH_0875|M.thermoresistible__bu ATTADVIALAREVRDGVRAAFGIELVPEPVLVGCSL--- MSMEG_0928|M.smegmatis_MC2_155 ATTADVMALAGTVRAGVLDVFGIELTPEPILLGCVLSVP Mflv_0090|M.gilvum_PYR-GCK ATTADVLALARTVRDGVKAAFGIELTPEPVLVGCSL--- Mvan_0823|M.vanbaalenii_PYR-1 ATTADVIALARTVRDGVRAAFGIELTPEPVLIGCSL--- Mb0492|M.bovis_AF2122/97 ATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML--- Rv0482|M.tuberculosis_H37Rv ATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML--- MLBr_02447|M.leprae_Br4923 ATAEDVVTLARTVRNGVLEVFGITLEPEPALVGCVL--- MAV_4668|M.avium_104 ARSDDVIALARTIRDGVRSVFGITLVPEPVLLGCRL--- MMAR_0808|M.marinum_M ATAADVMVLARTVRDGVRDVFGITLKPEPVLVGCAL--- MUL_4552|M.ulcerans_Agy99 ATAADVMVLARTVRDGVRDVFGITLKPEPVLVGCAL--- MAB_4066c|M.abscessus_ATCC_199 GSTDELLTLARTVRDGVLETFGVRLVPEPVLVGCSL--- . : :::.** :* ** .**: * *** *:** *