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M. thermoresistible (build 8) TH_0776 ()

annotation: PROBABLE F420 BIOSYNTHESIS PROTEIN FBIA
coordinates: 1627120 - 1628142
length: 341

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0776-100% (341)PROBABLE F420 BIOSYNTHESIS PROTEIN FBIA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3289fbiA1e-14774.17% (333) LPPG:FO 2-phospho-L-lactate transferase
M. gilvum PYR-GCKMflv_4730-1e-16382.44% (336) LPPG:FO 2-phospho-L-lactate transferase
M. tuberculosis H37RvRv3261fbiA1e-14774.17% (333) LPPG:FO 2-phospho-L-lactate transferase
M. leprae Br4923MLBr_00759-1e-14874.41% (340) LPPG:FO 2-phospho-L-lactate transferase
M. abscessus ATCC 19977MAB_3607-1e-15076.42% (335) LPPG:FO 2-phospho-L-lactate transferase
M. marinum MMMAR_1281fbiA1e-14876.13% (331) F420 biosynthesis protein FbiA
M. avium 104MAV_4224cofD1e-15276.11% (339) LPPG:FO 2-phospho-L-lactate transferase
M. smegmatis MC2 155MSMEG_1830cofD1e-15881.33% (332) LPPG:FO 2-phospho-L-lactate transferase
M. ulcerans Agy99MUL_2606fbiA1e-14976.44% (331) LPPG:FO 2-phospho-L-lactate transferase
M. vanbaalenii PYR-1Mvan_1733-1e-16281.25% (336) LPPG:FO 2-phospho-L-lactate transferase

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00759|M.leprae_Br4923          MSSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVT
MAV_4224|M.avium_104                ----------------------------------------------MKVT
Mb3289|M.bovis_AF2122/97            ----------------------------------------------MKVT
Rv3261|M.tuberculosis_H37Rv         ----------------------------------------------MKVT
MMAR_1281|M.marinum_M               ----------------------------------------------MKLT
MUL_2606|M.ulcerans_Agy99           ----------------------------------------------MKLT
Mflv_4730|M.gilvum_PYR-GCK          ----------MTCFRRVALWRVYHAPTGRPDGFAHR-----LLSFDVKVT
Mvan_1733|M.vanbaalenii_PYR-1       ----------MTCFRRVALWRVYHVPSRDAVALFHR-----LVSFVVKVA
TH_0776|M.thermoresistible__bu      ------------------------------------------MSIDVKVT
MAB_3607|M.abscessus_ATCC_1997      -------MFAAGVKRRTKIHTIYDRQNRRGALVACRVIAGALVSVNVKVT
MSMEG_1830|M.smegmatis_MC2_155      ----------------------------------------------MKIT
                                                                                  ::::

MLBr_00759|M.leprae_Br4923          VLVGGVGGAHFLLGVQQLLGLGQFGPQQ----CPDTLTTGHELTAVVNIG
MAV_4224|M.avium_104                VLVGGVGGARFLLGVQQLFGLGQFRAQRHTHGRPDTAAGSHELTAIVNIG
Mb3289|M.bovis_AF2122/97            VLAGGVGGARFLLGVQQLLGLGQFAANS------AHSDADHQLSAVVNVG
Rv3261|M.tuberculosis_H37Rv         VLAGGVGGARFLLGVQQLLGLGQFAANS------AHSDADHQLSAVVNVG
MMAR_1281|M.marinum_M               VLVGGVGGARFLLGAQRLLGLGQFATPD--------DNARHELTAVVNIG
MUL_2606|M.ulcerans_Agy99           VLVGGVGGARFLLGAQRLLGLGQFATPD--------DNARHELTAVVNIG
Mflv_4730|M.gilvum_PYR-GCK          VLVGGVGGARFLLGVQHLLGLGQYGTDD--------TNEN-EATAVVNVG
Mvan_1733|M.vanbaalenii_PYR-1       VLVGGVGGARFLLGVQHLLGLGQFGTDD--------TNEH-EVTAVVNVG
TH_0776|M.thermoresistible__bu      VLVGGVGGARFLLGVQHLLGLGQFSARD--------AEVDGELTAVVNIG
MAB_3607|M.abscessus_ATCC_1997      VLVGGVGGARFLLGVQRLLGS------D--------PSKH-QINAVVNIG
MSMEG_1830|M.smegmatis_MC2_155      VLVGGVGGARFLLGVQNLLGLGSF-ADG--------PSKH-ELTAVVNIG
                                    **.******:****.*.*:*                     : .*:**:*

MLBr_00759|M.leprae_Br4923          DDAWIHGLRVCPDLDTCMYTLGDGIDPQRGWGHRDETWHAKEELARYGVQ
MAV_4224|M.avium_104                DDAWIHGLRVCPDLDTCMYTLGGGVDPERGWGHRDETWHAKEELARYGVQ
Mb3289|M.bovis_AF2122/97            DDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQ
Rv3261|M.tuberculosis_H37Rv         DDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQ
MMAR_1281|M.marinum_M               DDAWIHGLRICPDLDTCMYTLGGGVDPQRGWGHRDETWHAKEELARYGVQ
MUL_2606|M.ulcerans_Agy99           DDAWIHGLRICPDLDTCMYTLGGGVDPQRGWGHRDETWHAKEELARYGVQ
Mflv_4730|M.gilvum_PYR-GCK          DDAWMFGVRICPDLDTCMYTLGGGIDPERGWGHKNETWNAKEELAAYGVQ
Mvan_1733|M.vanbaalenii_PYR-1       DDAWMFGVRICPDLDTCMYTLGGGIDPERGWGHKNETWHAKEELAAYGVQ
TH_0776|M.thermoresistible__bu      DDAWMFGLRICPDLDTCMYTLGGGIDPERGWGHRNETWHAKEELAAYGVQ
MAB_3607|M.abscessus_ATCC_1997      DDAWMHGVRICPDLDTCMYTLGGAVDPERGWGHRGETWNAMEELAAYGAQ
MSMEG_1830|M.smegmatis_MC2_155      DDAWMHGVRICPDLDTCMYTLGGGIDPDRGWGHRNETWNAKEELAAYGVQ
                                    ****:.*:*:************..:**:****::.***:* :**. **.*

MLBr_00759|M.leprae_Br4923          PDWFELGDRDLATHLVRTQMLNAGYRLSQITTALCDRWQPGARLVPASDD
MAV_4224|M.avium_104                PDWFGLGDRDIGTHLVRTQMLNAGYPLTQITAALCDRWQPGARLLPVSDD
Mb3289|M.bovis_AF2122/97            PDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDD
Rv3261|M.tuberculosis_H37Rv         PDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDD
MMAR_1281|M.marinum_M               PDWFQLGDRDLATHLVRTQMLRAGYPLAQITTALCDRWQPGATLLPVSND
MUL_2606|M.ulcerans_Agy99           PDWFQLGDRDLATHLVRTQMLRAGYPLAQITTALCDRWQPGATLLPVSND
Mflv_4730|M.gilvum_PYR-GCK          PDWFGLGDRDLATHLVRTQMLRAGYPLSDVTEALCKRWSPGLRLLPASDD
Mvan_1733|M.vanbaalenii_PYR-1       PDWFGLGDRDLATHLVRTQMLRAGYPLSDVTQALCRRWSPGARLLPASDD
TH_0776|M.thermoresistible__bu      PDWFGLGDRDLATHLVRTQMLRAGYPLSQVTEALCHRWSPGARLLPASDD
MAB_3607|M.abscessus_ATCC_1997      PDWFSLGDRDLATHLIRSQMLRAGYPLSAVTEALCNRWQPGVRLLPASDD
MSMEG_1830|M.smegmatis_MC2_155      PDWFGLGDRDLATHLVRSQMLRAGYPLSQVTEALCKRWQPGARLLPASDE
                                    **** *****:.***:*:***.*** *: :* *** **.**  *:*.:::

MLBr_00759|M.leprae_Br4923          RCETHVVITDP----INDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEKAS
MAV_4224|M.avium_104                RCETHVVITDP----DDGSRRAIHFQEWWVRYRAQVPTHSFAFVGAEKAA
Mb3289|M.bovis_AF2122/97            RCETHVVITDP----VDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSS
Rv3261|M.tuberculosis_H37Rv         RCETHVVITDP----VDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSS
MMAR_1281|M.marinum_M               RCETHVVVTDP----TDQQQRAIHFQEWWVRYRAELPTHSFVFIGTETAS
MUL_2606|M.ulcerans_Agy99           RCETHVVVTDP----TDQQQRAIHFQEWWVRYRAELPTHSFAFIGTETAS
Mflv_4730|M.gilvum_PYR-GCK          RCETHVVITDP----DDGEKRAVHFQEWWVRHRAQVPTDSFAFVGADNAT
Mvan_1733|M.vanbaalenii_PYR-1       RSETHVVVTDP----EDGEKRAIHFQEWWVRHRAQIPTESFAFVGADKAT
TH_0776|M.thermoresistible__bu      RVETHVVVTDPGPGEHAGQQRAIHFQEWWVRHRAKVPTHSFAFVGAEQAK
MAB_3607|M.abscessus_ATCC_1997      RCETHVVITDP----TDGEQRAIHFQQWWVQHRAQVPTHSFAFIGADEAK
MSMEG_1830|M.smegmatis_MC2_155      RSETHVVITDP----TDGERRAIHFQEWWVRYRAKVPTHSFAYVGADQAT
                                    * *****:***       .::*:***:***::**::**.**.::*:: : 

MLBr_00759|M.leprae_Br4923          AATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYS
MAV_4224|M.avium_104                ATTETIAAIADADVILIAPSNPVVSVGAILAVPGVRGALRAAGAPIVGYS
Mb3289|M.bovis_AF2122/97            AATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYS
Rv3261|M.tuberculosis_H37Rv         AATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYS
MMAR_1281|M.marinum_M               ATTEVTAAIADADVVMLAPSNPVVSIGAILAVPGIRAALRATRAPIIGYS
MUL_2606|M.ulcerans_Agy99           ATTEVTAAIADADVVMLAPSNPVVSIGAILAVPGIRAALRATRAPIIGYS
Mflv_4730|M.gilvum_PYR-GCK          AAPGVTDAIEGADVVLIAPSNPVVSVGAILNVGGIRGALRSTKAPVIGYS
Mvan_1733|M.vanbaalenii_PYR-1       AAPGVTDAIEDADIVLIAPSNPVVSVGAILAVGGIRGALRSTKAPVIGYS
TH_0776|M.thermoresistible__bu      AGPGVVEAITEADVVLIAPSNPVVSIGAILAVPGIRGALRTTPAPVIGYS
MAB_3607|M.abscessus_ATCC_1997      SGPGVAEAIGEADVVLLAPSNPVVSIGAILAVGGVRGALRTTSAPVIGYS
MSMEG_1830|M.smegmatis_MC2_155      AGPGVVEAIGDADIVLLAPSNPVVSIGPILQIPGIRGALRSTSAPVIGYS
                                    : . .  *:  **::::********:*.** : *:*.*** : **::***

MLBr_00759|M.leprae_Br4923          PIIDGKPLRGMADKCLTVIGVQSTATAVGQHYGARRTTGILDCWLVHEDD
MAV_4224|M.avium_104                PIIGGKPLRGMADACLSVIGVESTAEAVGRHYGARRGTGILDCWLVSQDD
Mb3289|M.bovis_AF2122/97            PIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGD
Rv3261|M.tuberculosis_H37Rv         PIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGD
MMAR_1281|M.marinum_M               PIIAGKPVRGMADACLSVIGVDTTAEAVGRHYGARAATGVLDYWLVAEGD
MUL_2606|M.ulcerans_Agy99           PIIAGKPVRGMADACLSVIGVDTTAEAVGRHYGARAATGVLDYWLVAEGD
Mflv_4730|M.gilvum_PYR-GCK          PIIAGKPLRGMADACLSVIGVDSTSEAVGRHYGARSATGILDGWLIHEGD
Mvan_1733|M.vanbaalenii_PYR-1       PIIGGKPLRGMADACLTVIGVPSTSEAVGNHFGARSSTGILDGWLVHSGD
TH_0776|M.thermoresistible__bu      PIIAGKPLRGMADECLSVIGVPSTSEGVGRHYGSRKHTGILDGWLVHEGD
MAB_3607|M.abscessus_ATCC_1997      PIVSGKPLRGMADECLRVIGVEVSSQGVGEHFGARSQTGILDGWLVDEGD
MSMEG_1830|M.smegmatis_MC2_155      PIIAGKPLRGMADECLKVIGVESTSQAVGEFFGARAGTGLLDGWLVHEGD
                                    **:  **:***** ** ****  :: .**..:*:*  **:** **: ..*

MLBr_00759|M.leprae_Br4923          HAEIEGVAVRSIPLLMSSPKTTADMVNIGLQLAGVSA---
MAV_4224|M.avium_104                HADIEGVAVRAVPLMMTDPAATAEMVSAGLQLAGVTP---
Mb3289|M.bovis_AF2122/97            HAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA---
Rv3261|M.tuberculosis_H37Rv         HAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA---
MMAR_1281|M.marinum_M               QAEIDSVTVRSIPLLMSDPEATAQMVRAGLELAGVTV---
MUL_2606|M.ulcerans_Agy99           QAEIDSVTVRSIPLLMSDPEATAQMVRAGLELAGVTV---
Mflv_4730|M.gilvum_PYR-GCK          HADIDGVNVKAVPLLMSEPSVTAQMVRAGLELAGVAP---
Mvan_1733|M.vanbaalenii_PYR-1       HASVDGVAVRSIPLLMTDPAATAEMVRAGMELAGVSP---
TH_0776|M.thermoresistible__bu      HADIDGVDVRAVPLLMTEPAATAEMVRAGLQLAGLAGERR
MAB_3607|M.abscessus_ATCC_1997      AAHIAGVQVRSVPLLMTDPDATAAMVRAGLDLAGVTL---
MSMEG_1830|M.smegmatis_MC2_155      HAQIEGVKVKAVPLLMTDPEATAAMVRAGLDLAGVSL---
                                     * : .* *:::**:*:.* .** **  * :***: