For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TCFRRVALWRVYHVPSRDAVALFHRLVSFVVKVAVLVGGVGGARFLLGVQHLLGLGQFGTDDTNEHEVTA VVNVGDDAWMFGVRICPDLDTCMYTLGGGIDPERGWGHKNETWHAKEELAAYGVQPDWFGLGDRDLATHL VRTQMLRAGYPLSDVTQALCRRWSPGARLLPASDDRSETHVVVTDPEDGEKRAIHFQEWWVRHRAQIPTE SFAFVGADKATAAPGVTDAIEDADIVLIAPSNPVVSVGAILAVGGIRGALRSTKAPVIGYSPIIGGKPLR GMADACLTVIGVPSTSEAVGNHFGARSSTGILDGWLVHSGDHASVDGVAVRSIPLLMTDPAATAEMVRAG MELAGVSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1733 | - | - | 100% (359) | LPPG:FO 2-phospho-L-lactate transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3289 | fbiA | 1e-148 | 73.56% (329) | LPPG:FO 2-phospho-L-lactate transferase |
| M. gilvum PYR-GCK | Mflv_4730 | - | 0.0 | 86.07% (359) | LPPG:FO 2-phospho-L-lactate transferase |
| M. tuberculosis H37Rv | Rv3261 | fbiA | 1e-148 | 73.56% (329) | LPPG:FO 2-phospho-L-lactate transferase |
| M. leprae Br4923 | MLBr_00759 | - | 1e-149 | 71.63% (349) | LPPG:FO 2-phospho-L-lactate transferase |
| M. abscessus ATCC 19977 | MAB_3607 | - | 1e-152 | 71.31% (359) | LPPG:FO 2-phospho-L-lactate transferase |
| M. marinum M | MMAR_1281 | fbiA | 1e-149 | 75.00% (328) | F420 biosynthesis protein FbiA |
| M. avium 104 | MAV_4224 | cofD | 1e-153 | 75.07% (337) | LPPG:FO 2-phospho-L-lactate transferase |
| M. smegmatis MC2 155 | MSMEG_1830 | cofD | 1e-160 | 80.43% (327) | LPPG:FO 2-phospho-L-lactate transferase |
| M. thermoresistible (build 8) | TH_0776 | - | 1e-163 | 81.25% (336) | PROBABLE F420 BIOSYNTHESIS PROTEIN FBIA |
| M. ulcerans Agy99 | MUL_2606 | fbiA | 1e-150 | 75.30% (328) | LPPG:FO 2-phospho-L-lactate transferase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00759|M.leprae_Br4923 MSSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVT
MAV_4224|M.avium_104 ----------------------------------------------MKVT
Mb3289|M.bovis_AF2122/97 ----------------------------------------------MKVT
Rv3261|M.tuberculosis_H37Rv ----------------------------------------------MKVT
MMAR_1281|M.marinum_M ----------------------------------------------MKLT
MUL_2606|M.ulcerans_Agy99 ----------------------------------------------MKLT
Mvan_1733|M.vanbaalenii_PYR-1 ----------MTCFRRVALWRVYHVPSRDAVALFHR-----LVSFVVKVA
Mflv_4730|M.gilvum_PYR-GCK ----------MTCFRRVALWRVYHAPTGRPDGFAHR-----LLSFDVKVT
TH_0776|M.thermoresistible__bu ------------------------------------------MSIDVKVT
MAB_3607|M.abscessus_ATCC_1997 -------MFAAGVKRRTKIHTIYDRQNRRGALVACRVIAGALVSVNVKVT
MSMEG_1830|M.smegmatis_MC2_155 ----------------------------------------------MKIT
::::
MLBr_00759|M.leprae_Br4923 VLVGGVGGAHFLLGVQQLLGLGQFGPQQ----CPDTLTTGHELTAVVNIG
MAV_4224|M.avium_104 VLVGGVGGARFLLGVQQLFGLGQFRAQRHTHGRPDTAAGSHELTAIVNIG
Mb3289|M.bovis_AF2122/97 VLAGGVGGARFLLGVQQLLGLGQFAANS------AHSDADHQLSAVVNVG
Rv3261|M.tuberculosis_H37Rv VLAGGVGGARFLLGVQQLLGLGQFAANS------AHSDADHQLSAVVNVG
MMAR_1281|M.marinum_M VLVGGVGGARFLLGAQRLLGLGQFATPD--------DNARHELTAVVNIG
MUL_2606|M.ulcerans_Agy99 VLVGGVGGARFLLGAQRLLGLGQFATPD--------DNARHELTAVVNIG
Mvan_1733|M.vanbaalenii_PYR-1 VLVGGVGGARFLLGVQHLLGLGQFGTDD--------TNEH-EVTAVVNVG
Mflv_4730|M.gilvum_PYR-GCK VLVGGVGGARFLLGVQHLLGLGQYGTDD--------TNEN-EATAVVNVG
TH_0776|M.thermoresistible__bu VLVGGVGGARFLLGVQHLLGLGQFSARD--------AEVDGELTAVVNIG
MAB_3607|M.abscessus_ATCC_1997 VLVGGVGGARFLLGVQRLLGS------D--------PSKH-QINAVVNIG
MSMEG_1830|M.smegmatis_MC2_155 VLVGGVGGARFLLGVQNLLGLGSF-ADG--------PSKH-ELTAVVNIG
**.******:****.*.*:* : .*:**:*
MLBr_00759|M.leprae_Br4923 DDAWIHGLRVCPDLDTCMYTLGDGIDPQRGWGHRDETWHAKEELARYGVQ
MAV_4224|M.avium_104 DDAWIHGLRVCPDLDTCMYTLGGGVDPERGWGHRDETWHAKEELARYGVQ
Mb3289|M.bovis_AF2122/97 DDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQ
Rv3261|M.tuberculosis_H37Rv DDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQ
MMAR_1281|M.marinum_M DDAWIHGLRICPDLDTCMYTLGGGVDPQRGWGHRDETWHAKEELARYGVQ
MUL_2606|M.ulcerans_Agy99 DDAWIHGLRICPDLDTCMYTLGGGVDPQRGWGHRDETWHAKEELARYGVQ
Mvan_1733|M.vanbaalenii_PYR-1 DDAWMFGVRICPDLDTCMYTLGGGIDPERGWGHKNETWHAKEELAAYGVQ
Mflv_4730|M.gilvum_PYR-GCK DDAWMFGVRICPDLDTCMYTLGGGIDPERGWGHKNETWNAKEELAAYGVQ
TH_0776|M.thermoresistible__bu DDAWMFGLRICPDLDTCMYTLGGGIDPERGWGHRNETWHAKEELAAYGVQ
MAB_3607|M.abscessus_ATCC_1997 DDAWMHGVRICPDLDTCMYTLGGAVDPERGWGHRGETWNAMEELAAYGAQ
MSMEG_1830|M.smegmatis_MC2_155 DDAWMHGVRICPDLDTCMYTLGGGIDPDRGWGHRNETWNAKEELAAYGVQ
****:.*:*:************..:**:****::.***:* :**. **.*
MLBr_00759|M.leprae_Br4923 PDWFELGDRDLATHLVRTQMLNAGYRLSQITTALCDRWQPGARLVPASDD
MAV_4224|M.avium_104 PDWFGLGDRDIGTHLVRTQMLNAGYPLTQITAALCDRWQPGARLLPVSDD
Mb3289|M.bovis_AF2122/97 PDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDD
Rv3261|M.tuberculosis_H37Rv PDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDD
MMAR_1281|M.marinum_M PDWFQLGDRDLATHLVRTQMLRAGYPLAQITTALCDRWQPGATLLPVSND
MUL_2606|M.ulcerans_Agy99 PDWFQLGDRDLATHLVRTQMLRAGYPLAQITTALCDRWQPGATLLPVSND
Mvan_1733|M.vanbaalenii_PYR-1 PDWFGLGDRDLATHLVRTQMLRAGYPLSDVTQALCRRWSPGARLLPASDD
Mflv_4730|M.gilvum_PYR-GCK PDWFGLGDRDLATHLVRTQMLRAGYPLSDVTEALCKRWSPGLRLLPASDD
TH_0776|M.thermoresistible__bu PDWFGLGDRDLATHLVRTQMLRAGYPLSQVTEALCHRWSPGARLLPASDD
MAB_3607|M.abscessus_ATCC_1997 PDWFSLGDRDLATHLIRSQMLRAGYPLSAVTEALCNRWQPGVRLLPASDD
MSMEG_1830|M.smegmatis_MC2_155 PDWFGLGDRDLATHLVRSQMLRAGYPLSQVTEALCKRWQPGARLLPASDE
**** *****:.***:*:***.*** *: :* *** **.** *:*.:::
MLBr_00759|M.leprae_Br4923 RCETHVVITDP----INDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEKAS
MAV_4224|M.avium_104 RCETHVVITDP----DDGSRRAIHFQEWWVRYRAQVPTHSFAFVGAEKAA
Mb3289|M.bovis_AF2122/97 RCETHVVITDP----VDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSS
Rv3261|M.tuberculosis_H37Rv RCETHVVITDP----VDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSS
MMAR_1281|M.marinum_M RCETHVVVTDP----TDQQQRAIHFQEWWVRYRAELPTHSFVFIGTETAS
MUL_2606|M.ulcerans_Agy99 RCETHVVVTDP----TDQQQRAIHFQEWWVRYRAELPTHSFAFIGTETAS
Mvan_1733|M.vanbaalenii_PYR-1 RSETHVVVTDP----EDGEKRAIHFQEWWVRHRAQIPTESFAFVGADKAT
Mflv_4730|M.gilvum_PYR-GCK RCETHVVITDP----DDGEKRAVHFQEWWVRHRAQVPTDSFAFVGADNAT
TH_0776|M.thermoresistible__bu RVETHVVVTDPGPGEHAGQQRAIHFQEWWVRHRAKVPTHSFAFVGAEQAK
MAB_3607|M.abscessus_ATCC_1997 RCETHVVITDP----TDGEQRAIHFQQWWVQHRAQVPTHSFAFIGADEAK
MSMEG_1830|M.smegmatis_MC2_155 RSETHVVITDP----TDGERRAIHFQEWWVRYRAKVPTHSFAYVGADQAT
* *****:*** .::*:***:***::**::**.**.::*:: :
MLBr_00759|M.leprae_Br4923 AATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYS
MAV_4224|M.avium_104 ATTETIAAIADADVILIAPSNPVVSVGAILAVPGVRGALRAAGAPIVGYS
Mb3289|M.bovis_AF2122/97 AATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYS
Rv3261|M.tuberculosis_H37Rv AATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYS
MMAR_1281|M.marinum_M ATTEVTAAIADADVVMLAPSNPVVSIGAILAVPGIRAALRATRAPIIGYS
MUL_2606|M.ulcerans_Agy99 ATTEVTAAIADADVVMLAPSNPVVSIGAILAVPGIRAALRATRAPIIGYS
Mvan_1733|M.vanbaalenii_PYR-1 AAPGVTDAIEDADIVLIAPSNPVVSVGAILAVGGIRGALRSTKAPVIGYS
Mflv_4730|M.gilvum_PYR-GCK AAPGVTDAIEGADVVLIAPSNPVVSVGAILNVGGIRGALRSTKAPVIGYS
TH_0776|M.thermoresistible__bu AGPGVVEAITEADVVLIAPSNPVVSIGAILAVPGIRGALRTTPAPVIGYS
MAB_3607|M.abscessus_ATCC_1997 SGPGVAEAIGEADVVLLAPSNPVVSIGAILAVGGVRGALRTTSAPVIGYS
MSMEG_1830|M.smegmatis_MC2_155 AGPGVVEAIGDADIVLLAPSNPVVSIGPILQIPGIRGALRSTSAPVIGYS
: . . *: **::::********:*.** : *:*.*** : **::***
MLBr_00759|M.leprae_Br4923 PIIDGKPLRGMADKCLTVIGVQSTATAVGQHYGARRTTGILDCWLVHEDD
MAV_4224|M.avium_104 PIIGGKPLRGMADACLSVIGVESTAEAVGRHYGARRGTGILDCWLVSQDD
Mb3289|M.bovis_AF2122/97 PIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGD
Rv3261|M.tuberculosis_H37Rv PIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGD
MMAR_1281|M.marinum_M PIIAGKPVRGMADACLSVIGVDTTAEAVGRHYGARAATGVLDYWLVAEGD
MUL_2606|M.ulcerans_Agy99 PIIAGKPVRGMADACLSVIGVDTTAEAVGRHYGARAATGVLDYWLVAEGD
Mvan_1733|M.vanbaalenii_PYR-1 PIIGGKPLRGMADACLTVIGVPSTSEAVGNHFGARSSTGILDGWLVHSGD
Mflv_4730|M.gilvum_PYR-GCK PIIAGKPLRGMADACLSVIGVDSTSEAVGRHYGARSATGILDGWLIHEGD
TH_0776|M.thermoresistible__bu PIIAGKPLRGMADECLSVIGVPSTSEGVGRHYGSRKHTGILDGWLVHEGD
MAB_3607|M.abscessus_ATCC_1997 PIVSGKPLRGMADECLRVIGVEVSSQGVGEHFGARSQTGILDGWLVDEGD
MSMEG_1830|M.smegmatis_MC2_155 PIIAGKPLRGMADECLKVIGVESTSQAVGEFFGARAGTGLLDGWLVHEGD
**: **:***** ** **** :: .**..:*:* **:** **: ..*
MLBr_00759|M.leprae_Br4923 HAEIEGVAVRSIPLLMSSPKTTADMVNIGLQLAGVSA---
MAV_4224|M.avium_104 HADIEGVAVRAVPLMMTDPAATAEMVSAGLQLAGVTP---
Mb3289|M.bovis_AF2122/97 HAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA---
Rv3261|M.tuberculosis_H37Rv HAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA---
MMAR_1281|M.marinum_M QAEIDSVTVRSIPLLMSDPEATAQMVRAGLELAGVTV---
MUL_2606|M.ulcerans_Agy99 QAEIDSVTVRSIPLLMSDPEATAQMVRAGLELAGVTV---
Mvan_1733|M.vanbaalenii_PYR-1 HASVDGVAVRSIPLLMTDPAATAEMVRAGMELAGVSP---
Mflv_4730|M.gilvum_PYR-GCK HADIDGVNVKAVPLLMSEPSVTAQMVRAGLELAGVAP---
TH_0776|M.thermoresistible__bu HADIDGVDVRAVPLLMTEPAATAEMVRAGLQLAGLAGERR
MAB_3607|M.abscessus_ATCC_1997 AAHIAGVQVRSVPLLMTDPDATAAMVRAGLDLAGVTL---
MSMEG_1830|M.smegmatis_MC2_155 HAQIEGVKVKAVPLLMTDPEATAAMVRAGLDLAGVSL---
* : .* *:::**:*:.* .** ** * :***: