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VKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLG GGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGA RLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIM LAPSNPVVSIGAILAVPGIRAALREATAPIVGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARC ATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3261 | fbiA | - | 100% (331) | PROBABLE F420 BIOSYNTHESIS PROTEIN FBIA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3289 | fbiA | 0.0 | 100.00% (331) | LPPG:FO 2-phospho-L-lactate transferase |
| M. gilvum PYR-GCK | Mflv_4730 | - | 1e-145 | 72.04% (329) | LPPG:FO 2-phospho-L-lactate transferase |
| M. leprae Br4923 | MLBr_00759 | - | 1e-160 | 79.28% (333) | LPPG:FO 2-phospho-L-lactate transferase |
| M. abscessus ATCC 19977 | MAB_3607 | - | 1e-140 | 69.91% (329) | LPPG:FO 2-phospho-L-lactate transferase |
| M. marinum M | MMAR_1281 | fbiA | 1e-158 | 78.72% (329) | F420 biosynthesis protein FbiA |
| M. avium 104 | MAV_4224 | cofD | 1e-160 | 80.30% (335) | LPPG:FO 2-phospho-L-lactate transferase |
| M. smegmatis MC2 155 | MSMEG_1830 | cofD | 1e-148 | 73.25% (329) | LPPG:FO 2-phospho-L-lactate transferase |
| M. thermoresistible (build 8) | TH_0776 | - | 1e-147 | 74.17% (333) | PROBABLE F420 BIOSYNTHESIS PROTEIN FBIA |
| M. ulcerans Agy99 | MUL_2606 | fbiA | 1e-158 | 79.03% (329) | LPPG:FO 2-phospho-L-lactate transferase |
| M. vanbaalenii PYR-1 | Mvan_1733 | - | 1e-148 | 73.56% (329) | LPPG:FO 2-phospho-L-lactate transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3261|M.tuberculosis_H37Rv ----------------------------------------------MKVT
Mb3289|M.bovis_AF2122/97 ----------------------------------------------MKVT
MLBr_00759|M.leprae_Br4923 MSSASGHKLCADLFPPSLFHGVLWVGLNAPTLPRKQAVSRAVLSCGVRVT
MAV_4224|M.avium_104 ----------------------------------------------MKVT
MMAR_1281|M.marinum_M ----------------------------------------------MKLT
MUL_2606|M.ulcerans_Agy99 ----------------------------------------------MKLT
Mflv_4730|M.gilvum_PYR-GCK ----------MTCFRRVALWRVYHAPTGRPDGFAHR-----LLSFDVKVT
Mvan_1733|M.vanbaalenii_PYR-1 ----------MTCFRRVALWRVYHVPSRDAVALFHR-----LVSFVVKVA
TH_0776|M.thermoresistible__bu ------------------------------------------MSIDVKVT
MAB_3607|M.abscessus_ATCC_1997 -------MFAAGVKRRTKIHTIYDRQNRRGALVACRVIAGALVSVNVKVT
MSMEG_1830|M.smegmatis_MC2_155 ----------------------------------------------MKIT
::::
Rv3261|M.tuberculosis_H37Rv VLAGGVGGARFLLGVQQLLGLGQFAANS------AHSDADHQLSAVVNVG
Mb3289|M.bovis_AF2122/97 VLAGGVGGARFLLGVQQLLGLGQFAANS------AHSDADHQLSAVVNVG
MLBr_00759|M.leprae_Br4923 VLVGGVGGAHFLLGVQQLLGLGQFGPQQ----CPDTLTTGHELTAVVNIG
MAV_4224|M.avium_104 VLVGGVGGARFLLGVQQLFGLGQFRAQRHTHGRPDTAAGSHELTAIVNIG
MMAR_1281|M.marinum_M VLVGGVGGARFLLGAQRLLGLGQFATPD--------DNARHELTAVVNIG
MUL_2606|M.ulcerans_Agy99 VLVGGVGGARFLLGAQRLLGLGQFATPD--------DNARHELTAVVNIG
Mflv_4730|M.gilvum_PYR-GCK VLVGGVGGARFLLGVQHLLGLGQYGTDD--------TNEN-EATAVVNVG
Mvan_1733|M.vanbaalenii_PYR-1 VLVGGVGGARFLLGVQHLLGLGQFGTDD--------TNEH-EVTAVVNVG
TH_0776|M.thermoresistible__bu VLVGGVGGARFLLGVQHLLGLGQFSARD--------AEVDGELTAVVNIG
MAB_3607|M.abscessus_ATCC_1997 VLVGGVGGARFLLGVQRLLGS------D--------PSKH-QINAVVNIG
MSMEG_1830|M.smegmatis_MC2_155 VLVGGVGGARFLLGVQNLLGLGSF-ADG--------PSKH-ELTAVVNIG
**.******:****.*.*:* : .*:**:*
Rv3261|M.tuberculosis_H37Rv DDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQ
Mb3289|M.bovis_AF2122/97 DDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQ
MLBr_00759|M.leprae_Br4923 DDAWIHGLRVCPDLDTCMYTLGDGIDPQRGWGHRDETWHAKEELARYGVQ
MAV_4224|M.avium_104 DDAWIHGLRVCPDLDTCMYTLGGGVDPERGWGHRDETWHAKEELARYGVQ
MMAR_1281|M.marinum_M DDAWIHGLRICPDLDTCMYTLGGGVDPQRGWGHRDETWHAKEELARYGVQ
MUL_2606|M.ulcerans_Agy99 DDAWIHGLRICPDLDTCMYTLGGGVDPQRGWGHRDETWHAKEELARYGVQ
Mflv_4730|M.gilvum_PYR-GCK DDAWMFGVRICPDLDTCMYTLGGGIDPERGWGHKNETWNAKEELAAYGVQ
Mvan_1733|M.vanbaalenii_PYR-1 DDAWMFGVRICPDLDTCMYTLGGGIDPERGWGHKNETWHAKEELAAYGVQ
TH_0776|M.thermoresistible__bu DDAWMFGLRICPDLDTCMYTLGGGIDPERGWGHRNETWHAKEELAAYGVQ
MAB_3607|M.abscessus_ATCC_1997 DDAWMHGVRICPDLDTCMYTLGGAVDPERGWGHRGETWNAMEELAAYGAQ
MSMEG_1830|M.smegmatis_MC2_155 DDAWMHGVRICPDLDTCMYTLGGGIDPDRGWGHRNETWNAKEELAAYGVQ
****:.*:*:************..:**:****::.***:* :**. **.*
Rv3261|M.tuberculosis_H37Rv PDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDD
Mb3289|M.bovis_AF2122/97 PDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDD
MLBr_00759|M.leprae_Br4923 PDWFELGDRDLATHLVRTQMLNAGYRLSQITTALCDRWQPGARLVPASDD
MAV_4224|M.avium_104 PDWFGLGDRDIGTHLVRTQMLNAGYPLTQITAALCDRWQPGARLLPVSDD
MMAR_1281|M.marinum_M PDWFQLGDRDLATHLVRTQMLRAGYPLAQITTALCDRWQPGATLLPVSND
MUL_2606|M.ulcerans_Agy99 PDWFQLGDRDLATHLVRTQMLRAGYPLAQITTALCDRWQPGATLLPVSND
Mflv_4730|M.gilvum_PYR-GCK PDWFGLGDRDLATHLVRTQMLRAGYPLSDVTEALCKRWSPGLRLLPASDD
Mvan_1733|M.vanbaalenii_PYR-1 PDWFGLGDRDLATHLVRTQMLRAGYPLSDVTQALCRRWSPGARLLPASDD
TH_0776|M.thermoresistible__bu PDWFGLGDRDLATHLVRTQMLRAGYPLSQVTEALCHRWSPGARLLPASDD
MAB_3607|M.abscessus_ATCC_1997 PDWFSLGDRDLATHLIRSQMLRAGYPLSAVTEALCNRWQPGVRLLPASDD
MSMEG_1830|M.smegmatis_MC2_155 PDWFGLGDRDLATHLVRSQMLRAGYPLSQVTEALCKRWQPGARLLPASDE
**** *****:.***:*:***.*** *: :* *** **.** *:*.:::
Rv3261|M.tuberculosis_H37Rv RCETHVVITDP----VDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSS
Mb3289|M.bovis_AF2122/97 RCETHVVITDP----VDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSS
MLBr_00759|M.leprae_Br4923 RCETHVVITDP----INDSRRAIHFQEWWVRYRAQVPTHSFAYVGAEKAS
MAV_4224|M.avium_104 RCETHVVITDP----DDGSRRAIHFQEWWVRYRAQVPTHSFAFVGAEKAA
MMAR_1281|M.marinum_M RCETHVVVTDP----TDQQQRAIHFQEWWVRYRAELPTHSFVFIGTETAS
MUL_2606|M.ulcerans_Agy99 RCETHVVVTDP----TDQQQRAIHFQEWWVRYRAELPTHSFAFIGTETAS
Mflv_4730|M.gilvum_PYR-GCK RCETHVVITDP----DDGEKRAVHFQEWWVRHRAQVPTDSFAFVGADNAT
Mvan_1733|M.vanbaalenii_PYR-1 RSETHVVVTDP----EDGEKRAIHFQEWWVRHRAQIPTESFAFVGADKAT
TH_0776|M.thermoresistible__bu RVETHVVVTDPGPGEHAGQQRAIHFQEWWVRHRAKVPTHSFAFVGAEQAK
MAB_3607|M.abscessus_ATCC_1997 RCETHVVITDP----TDGEQRAIHFQQWWVQHRAQVPTHSFAFIGADEAK
MSMEG_1830|M.smegmatis_MC2_155 RSETHVVITDP----TDGERRAIHFQEWWVRYRAKVPTHSFAYVGADQAT
* *****:*** .::*:***:***::**::**.**.::*:: :
Rv3261|M.tuberculosis_H37Rv AATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYS
Mb3289|M.bovis_AF2122/97 AATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYS
MLBr_00759|M.leprae_Br4923 AATEAVAAIADADVILVAPSNPVVSIGAILAIPGIRGALRTTTAPVVGYS
MAV_4224|M.avium_104 ATTETIAAIADADVILIAPSNPVVSVGAILAVPGVRGALRAAGAPIVGYS
MMAR_1281|M.marinum_M ATTEVTAAIADADVVMLAPSNPVVSIGAILAVPGIRAALRATRAPIIGYS
MUL_2606|M.ulcerans_Agy99 ATTEVTAAIADADVVMLAPSNPVVSIGAILAVPGIRAALRATRAPIIGYS
Mflv_4730|M.gilvum_PYR-GCK AAPGVTDAIEGADVVLIAPSNPVVSVGAILNVGGIRGALRSTKAPVIGYS
Mvan_1733|M.vanbaalenii_PYR-1 AAPGVTDAIEDADIVLIAPSNPVVSVGAILAVGGIRGALRSTKAPVIGYS
TH_0776|M.thermoresistible__bu AGPGVVEAITEADVVLIAPSNPVVSIGAILAVPGIRGALRTTPAPVIGYS
MAB_3607|M.abscessus_ATCC_1997 SGPGVAEAIGEADVVLLAPSNPVVSIGAILAVGGVRGALRTTSAPVIGYS
MSMEG_1830|M.smegmatis_MC2_155 AGPGVVEAIGDADIVLLAPSNPVVSIGPILQIPGIRGALRSTSAPVIGYS
: . . *: **::::********:*.** : *:*.*** : **::***
Rv3261|M.tuberculosis_H37Rv PIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGD
Mb3289|M.bovis_AF2122/97 PIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGD
MLBr_00759|M.leprae_Br4923 PIIDGKPLRGMADKCLTVIGVQSTATAVGQHYGARRTTGILDCWLVHEDD
MAV_4224|M.avium_104 PIIGGKPLRGMADACLSVIGVESTAEAVGRHYGARRGTGILDCWLVSQDD
MMAR_1281|M.marinum_M PIIAGKPVRGMADACLSVIGVDTTAEAVGRHYGARAATGVLDYWLVAEGD
MUL_2606|M.ulcerans_Agy99 PIIAGKPVRGMADACLSVIGVDTTAEAVGRHYGARAATGVLDYWLVAEGD
Mflv_4730|M.gilvum_PYR-GCK PIIAGKPLRGMADACLSVIGVDSTSEAVGRHYGARSATGILDGWLIHEGD
Mvan_1733|M.vanbaalenii_PYR-1 PIIGGKPLRGMADACLTVIGVPSTSEAVGNHFGARSSTGILDGWLVHSGD
TH_0776|M.thermoresistible__bu PIIAGKPLRGMADECLSVIGVPSTSEGVGRHYGSRKHTGILDGWLVHEGD
MAB_3607|M.abscessus_ATCC_1997 PIVSGKPLRGMADECLRVIGVEVSSQGVGEHFGARSQTGILDGWLVDEGD
MSMEG_1830|M.smegmatis_MC2_155 PIIAGKPLRGMADECLKVIGVESTSQAVGEFFGARAGTGLLDGWLVHEGD
**: **:***** ** **** :: .**..:*:* **:** **: ..*
Rv3261|M.tuberculosis_H37Rv HAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA---
Mb3289|M.bovis_AF2122/97 HAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA---
MLBr_00759|M.leprae_Br4923 HAEIEGVAVRSIPLLMSSPKTTADMVNIGLQLAGVSA---
MAV_4224|M.avium_104 HADIEGVAVRAVPLMMTDPAATAEMVSAGLQLAGVTP---
MMAR_1281|M.marinum_M QAEIDSVTVRSIPLLMSDPEATAQMVRAGLELAGVTV---
MUL_2606|M.ulcerans_Agy99 QAEIDSVTVRSIPLLMSDPEATAQMVRAGLELAGVTV---
Mflv_4730|M.gilvum_PYR-GCK HADIDGVNVKAVPLLMSEPSVTAQMVRAGLELAGVAP---
Mvan_1733|M.vanbaalenii_PYR-1 HASVDGVAVRSIPLLMTDPAATAEMVRAGMELAGVSP---
TH_0776|M.thermoresistible__bu HADIDGVDVRAVPLLMTEPAATAEMVRAGLQLAGLAGERR
MAB_3607|M.abscessus_ATCC_1997 AAHIAGVQVRSVPLLMTDPDATAAMVRAGLDLAGVTL---
MSMEG_1830|M.smegmatis_MC2_155 HAQIEGVKVKAVPLLMTDPEATAAMVRAGLDLAGVSL---
* : .* *:::**:*:.* .** ** * :***: