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M. thermoresistible (build 8) TH_0692 (thyA)

annotation: PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)
coordinates: 1484524 - 1485336
length: 271

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0692 thyA - 100% (271) PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2786c thyA 1e-139 86.26% (262) thymidylate synthase
M. gilvum PYR-GCK Mflv_4007 thyA 1e-141 87.79% (262) thymidylate synthase
M. tuberculosis H37Rv Rv2764c thyA 1e-139 86.26% (262) thymidylate synthase
M. leprae Br4923 MLBr_01519 thyA 1e-132 80.68% (264) thymidylate synthase
M. abscessus ATCC 19977 MAB_3091c - 1e-134 83.02% (265) thymidylate synthase (ThyA)
M. marinum M MMAR_1956 thyA 1e-135 83.71% (264) thymidylate synthase ThyA
M. avium 104 MAV_3652 thyA 1e-141 87.12% (264) thymidylate synthase
M. smegmatis MC2 155 MSMEG_2670 thyA 1e-142 87.50% (264) thymidylate synthase
M. ulcerans Agy99 MUL_2178 thyA 1e-136 84.09% (264) thymidylate synthase
M. vanbaalenii PYR-1 Mvan_2380 thyA 1e-138 85.98% (264) thymidylate synthase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0692|M.thermoresistible__bu      VPINGSIPTPYEDLLRLVLERGTPKADRTGTGTRSLFGHQMRYDLSAGFP
MAB_3091c|M.abscessus_ATCC_199      ----MSLPTPYEDLLRLVLEEGTPKADRTGTGTRSVFGHQLRYRLEDGFP
Mflv_4007|M.gilvum_PYR-GCK          ----MPTATPYEDLLRLVLDTGTPKSDRTGTGTRSLFGHQMRYDLNAGFP
Mvan_2380|M.vanbaalenii_PYR-1       ----MPIATPYEDLLRLVLDTGTTKSDRTGTGTRSLFGHQMRYDLNAGFP
MSMEG_2670|M.smegmatis_MC2_155      ----MPIDTPYEDLLRLVTERGTPKSDRTGTGTRSLFGHQMRYDLSAGFP
Mb2786c|M.bovis_AF2122/97           -------MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFP
Rv2764c|M.tuberculosis_H37Rv        -------MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFP
MMAR_1956|M.marinum_M               ----MPIATPYEDLLRRVLETGTAKSDRTGTGTRSLFGQQIRYDLGCGFP
MUL_2178|M.ulcerans_Agy99           ----MPIATPYEDLLRRVLETGTAKSDRTGTGTRSLFGQQIRYDLGCGFP
MLBr_01519|M.leprae_Br4923          ----MLIATPYEDLLRLVLDCGVAKMDRTGTGTRSLFGQQLRYDLSVGFP
MAV_3652|M.avium_104                ----MPIPTPYEDLLRLVLDRGTAKSDRTGTGTRSLFGQQLRYDLSAGFP
                                            ******** * : *..* *********:**:*:** *  ***

TH_0692|M.thermoresistible__bu      LITTKKVHTKSVIYELLWFLRGDSNVRWLQDRGVTIWDEWADDDGELGPV
MAB_3091c|M.abscessus_ATCC_199      LITTKKVHLKSVIYELLWFLRGESNVRWLQERGVTIWDEWASEAGELGPV
Mflv_4007|M.gilvum_PYR-GCK          LITTKKVHTKSIVYELLWFLRGDSNVRWLQERGVTIWDEWASPTGDLGPV
Mvan_2380|M.vanbaalenii_PYR-1       LITTKKVHTKSIVYELLWFLRGDSNVRWLQEHGVTIWDEWASPTGDLGPV
MSMEG_2670|M.smegmatis_MC2_155      LITTKKVHTKSVIYELLWFLRGDSNVRWLQEHGVTIWDEWASETGDLGPI
Mb2786c|M.bovis_AF2122/97           LLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIWDEWASDTGELGPI
Rv2764c|M.tuberculosis_H37Rv        LLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIWDEWASDTGELGPI
MMAR_1956|M.marinum_M               LLTTKKVHFKSVVYELLWFLRGDSNVGWLQQHGVTIWDEWASETGDLGPI
MUL_2178|M.ulcerans_Agy99           LLTTKKVHFKSVVYELLWFLRGDSNVGWLQQHGVTIWDEWASETGDLGPI
MLBr_01519|M.leprae_Br4923          LVTTKKVHFKSVVYELLWFLRGDSNVAWLHEHGVNIWDEWASSTGDLGPI
MAV_3652|M.avium_104                LITTKKVHLKSVVYELLWFLRGDSNVDWLHRHGVTIWDEWASDTGDLGPI
                                    *:****** **: *********:**: **: :**.******.  *:***:

TH_0692|M.thermoresistible__bu      YGVQWRSWPTPSGEHVDQISAALELLRTDPDSRRIIVSAWNVADLDEMAL
MAB_3091c|M.abscessus_ATCC_199      YGVQWRAWPTPSGEHIDQISAALDLLRTNPDSRRNIVSAWNVGEIPQMAL
Mflv_4007|M.gilvum_PYR-GCK          YGVQWRSWPTPSGEHIDQISAALDLLKRDPDSRRNIVSAWNVGEIPQMAL
Mvan_2380|M.vanbaalenii_PYR-1       YGVQWRSWPTPSGAHIDQISAALDLLRRDPDSRRNIVSAWNVGEIPQMAL
MSMEG_2670|M.smegmatis_MC2_155      YGVQWRSWPTPSGEHIDQISSALELLKSDPDSRRNIVSAWNVGEIPQMAL
Mb2786c|M.bovis_AF2122/97           YGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMAL
Rv2764c|M.tuberculosis_H37Rv        YGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMAL
MMAR_1956|M.marinum_M               YGVQWRSWPTPSGEHIDQISAALELLRTDPDSRRIIVSAWNVGQIPQMAL
MUL_2178|M.ulcerans_Agy99           YGVQWRSWPTPSGEHIDQISAALELLRTDPDSRRIIVSAWNVGQIPQMAL
MLBr_01519|M.leprae_Br4923          YGVQWRSWPTSSGDYIDQISTALDLLRTEPDSRRIIVSAWNVGEIPQMAL
MAV_3652|M.avium_104                YGVQWRSWPTPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIPRMAL
                                    ******:**:.** ::****:**:**: :***** *******.:: .***

TH_0692|M.thermoresistible__bu      PPCHTLFQFYVAGGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
MAB_3091c|M.abscessus_ATCC_199      PPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
Mflv_4007|M.gilvum_PYR-GCK          PPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
Mvan_2380|M.vanbaalenii_PYR-1       PPCHAFFQFYVSGGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
MSMEG_2670|M.smegmatis_MC2_155      PPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
Mb2786c|M.bovis_AF2122/97           PPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
Rv2764c|M.tuberculosis_H37Rv        PPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
MMAR_1956|M.marinum_M               PPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
MUL_2178|M.ulcerans_Agy99           PPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
MLBr_01519|M.leprae_Br4923          PPCHAFFQFYVAQGRLSCQLYQRSADMFLGVPFNIASYALLTHMMAAQSG
MAV_3652|M.avium_104                PPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAG
                                    ****::*****: *:***********:*********************:*

TH_0692|M.thermoresistible__bu      LQVGEFIWTGGDCHIYDNHVEQVRLQLSRDPRPYPELELAPRDSIFDYTF
MAB_3091c|M.abscessus_ATCC_199      LGVGDFVWTGGDCHIYDNHVEQVTEQLSRDPYPYPTLVLAQRDSIFDYRY
Mflv_4007|M.gilvum_PYR-GCK          LGVGEFIWTGGDCHIYDNHVEQVTEQLSRDPRPYPELVLAPRDSIFDYTY
Mvan_2380|M.vanbaalenii_PYR-1       LGVGEFIWTGGDCHIYDNHVEQVTEQLSREPRPYPELVLAQRDSLFDYIY
MSMEG_2670|M.smegmatis_MC2_155      LDVGEFIWTGGDCHIYDNHTEQVALQLSREPRPYPELVLAPRDSIFDYTY
Mb2786c|M.bovis_AF2122/97           LSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEYTY
Rv2764c|M.tuberculosis_H37Rv        LSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEYTY
MMAR_1956|M.marinum_M               LSVGEFIWTGGDCHIYGNHVEQVTEQLRREPRPYPKLSLSQRDSIFDYTY
MUL_2178|M.ulcerans_Agy99           LSVGEFIWTGGDCHIYDNHVEQVTEQLRREPRPYPKLSLSQRDSIFDYTY
MLBr_01519|M.leprae_Br4923          LLVGEFVWTGGDCHIYDNHVEQVQLQLSREPRAYPELFLAQRDSIFDYVY
MAV_3652|M.avium_104                LSVGEFVWTGGDCHIYDNHVEQVRLQLSREPRPYPELVLAHRDSIFDYTY
                                    * **:*:*********.**.***  ** *:* .** * *: ***:*:* :

TH_0692|M.thermoresistible__bu      EDVVIRNYDPHPAIKAPVAV
MAB_3091c|M.abscessus_ATCC_199      EDITVENYQHHAAIKAPVAV
Mflv_4007|M.gilvum_PYR-GCK          EDVVIKNYEPHPAIKAPVAI
Mvan_2380|M.vanbaalenii_PYR-1       EDVVIKNYDPHPAIKAPVAV
MSMEG_2670|M.smegmatis_MC2_155      EDIAIVNYDPHPAIKAPVAV
Mb2786c|M.bovis_AF2122/97           EDIVVKNYDPHPAIKAPVAV
Rv2764c|M.tuberculosis_H37Rv        EDIVVKNYDPHPAIKAPVAV
MMAR_1956|M.marinum_M               EDVVVQDYDPHPAIKAPVAV
MUL_2178|M.ulcerans_Agy99           EDVVVQDYDPHPAIKAPVAV
MLBr_01519|M.leprae_Br4923          EDVVVTNYDPHPAIKAPVAI
MAV_3652|M.avium_104                DDVVVHNYDPHPAIKAPVAV
                                    :*:.: :*: *.*******:

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0692	thyA	-	100% (271)	PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)