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M. thermoresistible (build 8) TH_0660 ()

annotation: N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase mshB (GlcNAc-Ins deacetylase)
coordinates: 1418593 - 1419480
length: 296

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0660 - 100% (296) N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase mshB (GlcNAc-Ins deacetylase)
M. thermoresistible (build 8) TH_2167 - 8e-29 35.88% (301) mycothiol conjugate amidase Mca
M. thermoresistible (build 8) TH_0689 - 3e-06 27.65% (170) GlcNAc-PI de-N-acetylase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1203 mshB 1e-107 65.41% (292) N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha-
M. gilvum PYR-GCK Mflv_2165 - 1e-105 63.67% (289) LmbE family protein
M. tuberculosis H37Rv Rv1170 mshB 1e-107 65.41% (292) N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha-
M. leprae Br4923 MLBr_01495 - 1e-105 64.21% (299) hypothetical protein MLBr_01495
M. abscessus ATCC 19977 MAB_1316 - 3e-87 58.54% (287) putative
M. marinum M MMAR_4283 mshB 1e-109 69.42% (291) N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-
M. avium 104 MAV_1310 - 1e-104 67.13% (289) N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha-
M. smegmatis MC2 155 MSMEG_5129 - 1e-122 70.85% (295) N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha-
M. ulcerans Agy99 MUL_1017 mshB 1e-109 69.42% (291) N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-
M. vanbaalenii PYR-1 Mvan_4535 - 1e-105 64.93% (288) LmbE family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_0660|M.thermoresistible__bu      MDPNALPRLLFVHAHPDDETLMTGGTIAHYAARGADVRVVTCTLGEEGEV
MSMEG_5129|M.smegmatis_MC2_155      MSSHESPRLLFVHAHPDDETLTTGGTIAHYVARSAEVHVVTCTLGEEGEV
Mb1203|M.bovis_AF2122/97            MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEV
Rv1170|M.tuberculosis_H37Rv         MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEV
MMAR_4283|M.marinum_M               MP--ETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEV
MUL_1017|M.ulcerans_Agy99           MP--ETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEV
MLBr_01495|M.leprae_Br4923          MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEV
MAV_1310|M.avium_104                MA--ETPRLLFVHAHPDDESLGTGATIAHYTAAGADVRVVTCTLGEEGEV
Mflv_2165|M.gilvum_PYR-GCK          ---METPRLLFVHAHPDDETLTTGATIAHYTARGAEVQVITCTLGEEGEV
Mvan_4535|M.vanbaalenii_PYR-1       ---METARLLFVHAHPDDETLTTGATIAHYVARGAQVHVITCTLGEEGEV
MAB_1316|M.abscessus_ATCC_1997      ---MTTRRLMLVHAHPDDESLTTGGTIARYAAEGADVQLVTCTLGEEGEV
                                           **::********:* .*.***:*.: .*:*:::**********

TH_0660|M.thermoresistible__bu      IGDRYARLAVDHADQLGGYRICELTRALEALGVEEPEFLGGAGRWRDSGM
MSMEG_5129|M.smegmatis_MC2_155      IGERYAQLAVDHADQLGGYRIAELTAALQSLGLRGPRYLGGAGHWRDSGM
Mb1203|M.bovis_AF2122/97            IGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGM
Rv1170|M.tuberculosis_H37Rv         IGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGM
MMAR_4283|M.marinum_M               IGDRWAQLAVDHADQLGGYRIGELTAALQRLGVDAPIYLGGAGRWRDSGM
MUL_1017|M.ulcerans_Agy99           IGDRWAQLAVDHADQLGGYRIGELTAALQRLGVDAPIYLGGAGRWRDSGM
MLBr_01495|M.leprae_Br4923          IGDRWAELTVDHADQLGGYRIFELTEALRALGVSAPIYLGGAGRWRDSGM
MAV_1310|M.avium_104                IGERWAELAVDRADQLGGYRIGELTAALRELGVGEPCYLGGAGRWRDSGM
Mflv_2165|M.gilvum_PYR-GCK          IGDRWAQLAVDHADQLGGYRIGELTAALAALGVDRPRYLGGAGRWRDSGM
Mvan_4535|M.vanbaalenii_PYR-1       IGDEWAQLAVDRADQLGGYRIGELTAALAELGVDRPRFLGGAGRWRDSGM
MAB_1316|M.abscessus_ATCC_1997      IGDRWAQLAVDQADQLGGYRIGELSTALRHLGVDGPTFLGGAGRWRDSGM
                                    **:.:*.*:.*:********* **: **  **:  * :*****:******

TH_0660|M.thermoresistible__bu      VGTPRRHHPRFIDADIDEAVGALVRIIRRLRPHVVVTYDPNGGYGHPDHI
MSMEG_5129|M.smegmatis_MC2_155      AGTPSRGRQRWVDADLDEAVGALVAVIGEVRPHVVVTYDPNGGYGHPDHI
Mb1203|M.bovis_AF2122/97            AGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHV
Rv1170|M.tuberculosis_H37Rv         AGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHV
MMAR_4283|M.marinum_M               AGTEQRGRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDGGYGHPDHV
MUL_1017|M.ulcerans_Agy99           AGTEQRSRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDGGYGHPDHV
MLBr_01495|M.leprae_Br4923          RGTAPRRRQRFIDADENEAVGALVAIIRELRPHVVVTYDPHGGYGHPDHV
MAV_1310|M.avium_104                PGTPKRRRQRFIDADEREAVGALVAVIREQRPHVVVGYDPAGGYGHPDHV
Mflv_2165|M.gilvum_PYR-GCK          EGTPARRRERFVDGDVAEQTAVLAAAIDELRPHVVVTYDPNGGYGHPDHI
Mvan_4535|M.vanbaalenii_PYR-1       DGTPARQQQRFVDGDFAEQTATLAAAIDELRPHVVVTYDPNGGYGHPDHI
MAB_1316|M.abscessus_ATCC_1997      ADTTPLHPRAFAGADLNEAVGALTALIDEHRPHVVVTYDPFGGYGHPDHI
                                     .*       : ..*  : ...*.  * . ****** *** ********:

TH_0660|M.thermoresistible__bu      QAHRVTTAAVA-------AAGADDGHPDQPWQVPKFYWTVHARSAIDAGL
MSMEG_5129|M.smegmatis_MC2_155      QTHVVTTRAVA-------AAPEAVG-----WTVPKFYWTVTAISAMTAGL
Mb1203|M.bovis_AF2122/97            HTHTVTTAAVA----AAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGA
Rv1170|M.tuberculosis_H37Rv         HTHTVTTAAVA----AAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGA
MMAR_4283|M.marinum_M               QAHVVTTAAVA----AAGS-VGDCDYPGDPWVVPKFYWTILGLSAFLAGR
MUL_1017|M.ulcerans_Agy99           QAHVVTTAAVA----AAGS-VGDCDYPGDPWVVPKFYWTVLGVSAFLAGR
MLBr_01495|M.leprae_Br4923          HTHFITAAAVASSGVAAGLEVGADEYPGKPWKVPKFYWSVFALSAFEAGM
MAV_1310|M.avium_104                HVHTVTTAAVA--------AAGAGDFPGEPWAVPKFYWSVFATRPFEAAV
Mflv_2165|M.gilvum_PYR-GCK          HTHRLTTAAVE----------------AAAWQVPKFYWTVTSDSALRTGI
Mvan_4535|M.vanbaalenii_PYR-1       HAHRVTTAAVA----------------ASTWQVPKLYWTVTSSSALAAAL
MAB_1316|M.abscessus_ATCC_1997      QAHTVTTAAVE----------------KASWQVAKLYWTVIATSALETGL
                                    :.* :*: **                    * *.*:**:: .  .: :. 

TH_0660|M.thermoresistible__bu      RQLG--DVPADWIRVSIEDVP-FGYPDERIDAVIDTT-ACLPAKIAALKA
MSMEG_5129|M.smegmatis_MC2_155      QALG--DVPSEWIRVNAEDIP-FGFGDDQIDAVVDVT-AELPAKVGAMRA
Mb1203|M.bovis_AF2122/97            RALVPDDLRPEWVLPRADEIA-FGYSDDGIDAVVEADEQARAAKVAALAA
Rv1170|M.tuberculosis_H37Rv         RALVPDDLRPEWVLPRADEIA-FGYSDDGIDAVVEADEQARAAKVAALAA
MMAR_4283|M.marinum_M               QALTPDDLLPEWVLP-PEDIP-FIYPDERIDAVVTGDSDARAAKIAALAA
MUL_1017|M.ulcerans_Agy99           QALTPDDLLPEWVLP-PEDIP-FIYPDERIDAVVTGDSDARAAKIAALAA
MLBr_01495|M.leprae_Br4923          NALQGKDLRPEWTIPPREEFY-FGYSDKDIDAVVEATSDVWAAKTAALTA
MAV_1310|M.avium_104                QALTPEDLRPDWSMPSAEQFT-FGYADDHIDAVVAAGPHAWAAKRAALAA
Mflv_2165|M.gilvum_PYR-GCK          AALT--DVPDGWVTLTADDLPLVGFTDDTIDAALDLG-AHSAARVAAMHA
Mvan_4535|M.vanbaalenii_PYR-1       ASMG--AVPEEWIRVSADDLPLFGYSDEAIDAALDLT-AHESARVAALRA
MAB_1316|M.abscessus_ATCC_1997      ASIT--QLPPGCQPAPLDLIP--TFADEKISAAIDVS-GHREAKVAALRA
                                      :    :         : .    : *. *.*.:        *: .*: *

TH_0660|M.thermoresistible__bu      HATQVTVAPGEQAFTLSNNIAMPILAEEHYILVSGSKGPTDARGFETDLL
MSMEG_5129|M.smegmatis_MC2_155      HATQITVAPDGRAFALSNNIALPVLGEEHYVLVSGEAGPRDSRGWETDLL
Mb1203|M.bovis_AF2122/97            HATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLL
Rv1170|M.tuberculosis_H37Rv         HATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLL
MMAR_4283|M.marinum_M               HATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGARDERGWETDLL
MUL_1017|M.ulcerans_Agy99           HATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGARDERGWEIDLL
MLBr_01495|M.leprae_Br4923          HATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLL
MAV_1310|M.avium_104                HATQVVVGPTGRACALSNNVALPILDEEHYVLVAGAAGARDERGWETDLL
Mflv_2165|M.gilvum_PYR-GCK          HQTQITVAPDGRSFALSNDIALPVDATEYYVLARGEAGERDARGWETDLL
Mvan_4535|M.vanbaalenii_PYR-1       HRTQVSVSPDGRSFALSNNVALPVDPTEYYVLAAGSAGARDERGWETDLL
MAB_1316|M.abscessus_ATCC_1997      HATQLTVSDDGSSMALSNLIALPIADIEHFVLVRGEPG--VDTGWESDLF
                                    * **: *.    : :*** :.:*:   *:::*. *  *     *:* **:

TH_0660|M.thermoresistible__bu      AGLTLD-----
MSMEG_5129|M.smegmatis_MC2_155      AGLDLE-----
Mb1203|M.bovis_AF2122/97            AGLGFTASGT-
Rv1170|M.tuberculosis_H37Rv         AGLGFTASGT-
MMAR_4283|M.marinum_M               AGLGFTGFGT-
MUL_1017|M.ulcerans_Agy99           AGLGFTGFGT-
MLBr_01495|M.leprae_Br4923          AGLCLDGFDAR
MAV_1310|M.avium_104                AGLEFGAAPRR
Mflv_2165|M.gilvum_PYR-GCK          AGLNLR-----
Mvan_4535|M.vanbaalenii_PYR-1       SGLSVG-----
MAB_1316|M.abscessus_ATCC_1997      AGVEL------
                                    :*: .

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0660		-	100% (296)	N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase mshB (GlcNAc-Ins deacetylase)
M. thermoresistible (build 8)	TH_2167	-	8e-29	35.88% (301)	mycothiol conjugate amidase Mca
M. thermoresistible (build 8)	TH_0689	-	3e-06	27.65% (170)	GlcNAc-PI de-N-acetylase family protein