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MPETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEVIGDRWAQLAVDHADQLGGYRIG ELTAALQRLGVDAPIYLGGAGRWRDSGMAGTEQRSRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDG GYGHPDHVQAHVVTTAAVAAAGSVGDCDYPGDPWVVPKFYWTVLGVSAFLAGRQALTPDDLLPEWVLPPE DIPFIYPDERIDAVVTGDSDARAAKIAALAAHATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGA RDERGWEIDLLAGLGFTGFGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1017 | mshB | - | 100% (301) | N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB |
| M. ulcerans Agy99 | MUL_0198 | mca | 4e-27 | 34.21% (266) | mycothiol conjugate amidase Mca |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1203 | mshB | 1e-143 | 81.19% (303) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. gilvum PYR-GCK | Mflv_2165 | - | 1e-102 | 64.63% (294) | LmbE family protein |
| M. tuberculosis H37Rv | Rv1170 | mshB | 1e-143 | 81.19% (303) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. leprae Br4923 | MLBr_01495 | - | 1e-128 | 73.77% (305) | hypothetical protein MLBr_01495 |
| M. abscessus ATCC 19977 | MAB_1316 | - | 3e-88 | 59.79% (291) | putative |
| M. marinum M | MMAR_4283 | mshB | 1e-176 | 98.67% (301) | N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- |
| M. avium 104 | MAV_1310 | - | 1e-125 | 74.41% (297) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. smegmatis MC2 155 | MSMEG_5129 | - | 1e-111 | 69.05% (294) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. thermoresistible (build 8) | TH_0660 | - | 1e-109 | 69.42% (291) | N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D- |
| M. vanbaalenii PYR-1 | Mvan_4535 | - | 1e-100 | 64.75% (295) | LmbE family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2165|M.gilvum_PYR-GCK ---METPRLLFVHAHPDDETLTTGATIAHYTARGAEVQVITCTLGEEGEV
Mvan_4535|M.vanbaalenii_PYR-1 ---METARLLFVHAHPDDETLTTGATIAHYVARGAQVHVITCTLGEEGEV
MUL_1017|M.ulcerans_Agy99 MP--ETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEV
MMAR_4283|M.marinum_M MP--ETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEV
Mb1203|M.bovis_AF2122/97 MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEV
Rv1170|M.tuberculosis_H37Rv MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEV
MLBr_01495|M.leprae_Br4923 MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEV
MAV_1310|M.avium_104 MA--ETPRLLFVHAHPDDESLGTGATIAHYTAAGADVRVVTCTLGEEGEV
MSMEG_5129|M.smegmatis_MC2_155 MSSHESPRLLFVHAHPDDETLTTGGTIAHYVARSAEVHVVTCTLGEEGEV
TH_0660|M.thermoresistible__bu MDPNALPRLLFVHAHPDDETLMTGGTIAHYAARGADVRVVTCTLGEEGEV
MAB_1316|M.abscessus_ATCC_1997 ---MTTRRLMLVHAHPDDESLTTGGTIARYAAEGADVQLVTCTLGEEGEV
**::********:* .*.***:*.: .*:*:::**********
Mflv_2165|M.gilvum_PYR-GCK IGDRWAQLAVDHADQLGGYRIGELTAALAALGVDRPRYLGGAGRWRDSGM
Mvan_4535|M.vanbaalenii_PYR-1 IGDEWAQLAVDRADQLGGYRIGELTAALAELGVDRPRFLGGAGRWRDSGM
MUL_1017|M.ulcerans_Agy99 IGDRWAQLAVDHADQLGGYRIGELTAALQRLGVDAPIYLGGAGRWRDSGM
MMAR_4283|M.marinum_M IGDRWAQLAVDHADQLGGYRIGELTAALQRLGVDAPIYLGGAGRWRDSGM
Mb1203|M.bovis_AF2122/97 IGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGM
Rv1170|M.tuberculosis_H37Rv IGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGM
MLBr_01495|M.leprae_Br4923 IGDRWAELTVDHADQLGGYRIFELTEALRALGVSAPIYLGGAGRWRDSGM
MAV_1310|M.avium_104 IGERWAELAVDRADQLGGYRIGELTAALRELGVGEPCYLGGAGRWRDSGM
MSMEG_5129|M.smegmatis_MC2_155 IGERYAQLAVDHADQLGGYRIAELTAALQSLGLRGPRYLGGAGHWRDSGM
TH_0660|M.thermoresistible__bu IGDRYARLAVDHADQLGGYRICELTRALEALGVEEPEFLGGAGRWRDSGM
MAB_1316|M.abscessus_ATCC_1997 IGDRWAQLAVDQADQLGGYRIGELSTALRHLGVDGPTFLGGAGRWRDSGM
**:.:*.*:.*:********* **: ** **: * :*****:******
Mflv_2165|M.gilvum_PYR-GCK EGTPARRRERFVDGDVAEQTAVLAAAIDELRPHVVVTYDPNGGYGHPDHI
Mvan_4535|M.vanbaalenii_PYR-1 DGTPARQQQRFVDGDFAEQTATLAAAIDELRPHVVVTYDPNGGYGHPDHI
MUL_1017|M.ulcerans_Agy99 AGTEQRSRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDGGYGHPDHV
MMAR_4283|M.marinum_M AGTEQRGRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDGGYGHPDHV
Mb1203|M.bovis_AF2122/97 AGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHV
Rv1170|M.tuberculosis_H37Rv AGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHV
MLBr_01495|M.leprae_Br4923 RGTAPRRRQRFIDADENEAVGALVAIIRELRPHVVVTYDPHGGYGHPDHV
MAV_1310|M.avium_104 PGTPKRRRQRFIDADEREAVGALVAVIREQRPHVVVGYDPAGGYGHPDHV
MSMEG_5129|M.smegmatis_MC2_155 AGTPSRGRQRWVDADLDEAVGALVAVIGEVRPHVVVTYDPNGGYGHPDHI
TH_0660|M.thermoresistible__bu VGTPRRHHPRFIDADIDEAVGALVRIIRRLRPHVVVTYDPNGGYGHPDHI
MAB_1316|M.abscessus_ATCC_1997 ADTTPLHPRAFAGADLNEAVGALTALIDEHRPHVVVTYDPFGGYGHPDHI
.* : ..* : ...*. * . ****** *** ********:
Mflv_2165|M.gilvum_PYR-GCK HTHRLTTAAVE----------------AAAWQVPKFYWTVTSDSALRTGI
Mvan_4535|M.vanbaalenii_PYR-1 HAHRVTTAAVA----------------ASTWQVPKLYWTVTSSSALAAAL
MUL_1017|M.ulcerans_Agy99 QAHVVTTAAVA----AAGS-VGDCDYPGDPWVVPKFYWTVLGVSAFLAGR
MMAR_4283|M.marinum_M QAHVVTTAAVA----AAGS-VGDCDYPGDPWVVPKFYWTILGLSAFLAGR
Mb1203|M.bovis_AF2122/97 HTHTVTTAAVA----AAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGA
Rv1170|M.tuberculosis_H37Rv HTHTVTTAAVA----AAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGA
MLBr_01495|M.leprae_Br4923 HTHFITAAAVASSGVAAGLEVGADEYPGKPWKVPKFYWSVFALSAFEAGM
MAV_1310|M.avium_104 HVHTVTTAAVA--------AAGAGDFPGEPWAVPKFYWSVFATRPFEAAV
MSMEG_5129|M.smegmatis_MC2_155 QTHVVTTRAVA-------AAPEAVG-----WTVPKFYWTVTAISAMTAGL
TH_0660|M.thermoresistible__bu QAHRVTTAAVA-------AAGADDGHPDQPWQVPKFYWTVHARSAIDAGL
MAB_1316|M.abscessus_ATCC_1997 QAHTVTTAAVE----------------KASWQVAKLYWTVIATSALETGL
:.* :*: ** * *.*:**:: . .: :.
Mflv_2165|M.gilvum_PYR-GCK AALT--DVPDGWVTLTADDLPLVGFTDDTIDAALDLG-AHSAARVAAMHA
Mvan_4535|M.vanbaalenii_PYR-1 ASMG--AVPEEWIRVSADDLPLFGYSDEAIDAALDLT-AHESARVAALRA
MUL_1017|M.ulcerans_Agy99 QALTPDDLLPEWVLP-PEDIP-FIYPDERIDAVVTGDSDARAAKIAALAA
MMAR_4283|M.marinum_M QALTPDDLLPEWVLP-PEDIP-FIYPDERIDAVVTGDSDARAAKIAALAA
Mb1203|M.bovis_AF2122/97 RALVPDDLRPEWVLPRADEIA-FGYSDDGIDAVVEADEQARAAKVAALAA
Rv1170|M.tuberculosis_H37Rv RALVPDDLRPEWVLPRADEIA-FGYSDDGIDAVVEADEQARAAKVAALAA
MLBr_01495|M.leprae_Br4923 NALQGKDLRPEWTIPPREEFY-FGYSDKDIDAVVEATSDVWAAKTAALTA
MAV_1310|M.avium_104 QALTPEDLRPDWSMPSAEQFT-FGYADDHIDAVVAAGPHAWAAKRAALAA
MSMEG_5129|M.smegmatis_MC2_155 QALG--DVPSEWIRVNAEDIP-FGFGDDQIDAVVDVT-AELPAKVGAMRA
TH_0660|M.thermoresistible__bu RQLG--DVPADWIRVSIEDVP-FGYPDERIDAVIDTT-ACLPAKIAALKA
MAB_1316|M.abscessus_ATCC_1997 ASIT--QLPPGCQPAPLDLIP--TFADEKISAAIDVS-GHREAKVAALRA
: : : . : *. *.*.: *: .*: *
Mflv_2165|M.gilvum_PYR-GCK HQTQITVAPDGRSFALSNDIALPVDATEYYVLARGEAGERDARGWETDLL
Mvan_4535|M.vanbaalenii_PYR-1 HRTQVSVSPDGRSFALSNNVALPVDPTEYYVLAAGSAGARDERGWETDLL
MUL_1017|M.ulcerans_Agy99 HATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGARDERGWEIDLL
MMAR_4283|M.marinum_M HATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGARDERGWETDLL
Mb1203|M.bovis_AF2122/97 HATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLL
Rv1170|M.tuberculosis_H37Rv HATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLL
MLBr_01495|M.leprae_Br4923 HATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLL
MAV_1310|M.avium_104 HATQVVVGPTGRACALSNNVALPILDEEHYVLVAGAAGARDERGWETDLL
MSMEG_5129|M.smegmatis_MC2_155 HATQITVAPDGRAFALSNNIALPVLGEEHYVLVSGEAGPRDSRGWETDLL
TH_0660|M.thermoresistible__bu HATQVTVAPGEQAFTLSNNIAMPILAEEHYILVSGSKGPTDARGFETDLL
MAB_1316|M.abscessus_ATCC_1997 HATQLTVSDDGSSMALSNLIALPIADIEHFVLVRGEPG--VDTGWESDLF
* **: *. : :*** :.:*: *:::*. * * *:* **:
Mflv_2165|M.gilvum_PYR-GCK AGLNLR-----
Mvan_4535|M.vanbaalenii_PYR-1 SGLSVG-----
MUL_1017|M.ulcerans_Agy99 AGLGFTGFGT-
MMAR_4283|M.marinum_M AGLGFTGFGT-
Mb1203|M.bovis_AF2122/97 AGLGFTASGT-
Rv1170|M.tuberculosis_H37Rv AGLGFTASGT-
MLBr_01495|M.leprae_Br4923 AGLCLDGFDAR
MAV_1310|M.avium_104 AGLEFGAAPRR
MSMEG_5129|M.smegmatis_MC2_155 AGLDLE-----
TH_0660|M.thermoresistible__bu AGLTLD-----
MAB_1316|M.abscessus_ATCC_1997 AGVEL------
:*: .