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ETARLLFVHAHPDDETLTTGATIAHYVARGAQVHVITCTLGEEGEVIGDEWAQLAVDRADQLGGYRIGEL TAALAELGVDRPRFLGGAGRWRDSGMDGTPARQQQRFVDGDFAEQTATLAAAIDELRPHVVVTYDPNGGY GHPDHIHAHRVTTAAVAASTWQVPKLYWTVTSSSALAAALASMGAVPEEWIRVSADDLPLFGYSDEAIDA ALDLTAHESARVAALRAHRTQVSVSPDGRSFALSNNVALPVDPTEYYVLAAGSAGARDERGWETDLLSGL SVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4535 | - | - | 100% (284) | LmbE family protein |
| M. vanbaalenii PYR-1 | Mvan_4667 | - | 1e-21 | 30.71% (280) | LmbE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1203 | mshB | 1e-104 | 64.65% (297) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. gilvum PYR-GCK | Mflv_2165 | - | 1e-134 | 79.15% (283) | LmbE family protein |
| M. tuberculosis H37Rv | Rv1170 | mshB | 1e-104 | 64.65% (297) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. leprae Br4923 | MLBr_01495 | - | 4e-97 | 59.87% (299) | hypothetical protein MLBr_01495 |
| M. abscessus ATCC 19977 | MAB_1316 | - | 6e-94 | 60.42% (283) | putative |
| M. marinum M | MMAR_4283 | mshB | 1e-101 | 65.20% (296) | N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- |
| M. avium 104 | MAV_1310 | - | 1e-101 | 63.51% (296) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. smegmatis MC2 155 | MSMEG_5129 | - | 1e-113 | 68.18% (286) | N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- |
| M. thermoresistible (build 8) | TH_0660 | - | 1e-105 | 64.93% (288) | N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D- |
| M. ulcerans Agy99 | MUL_1017 | mshB | 1e-100 | 65.20% (296) | N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4535|M.vanbaalenii_PYR-1 ---METARLLFVHAHPDDETLTTGATIAHYVARGAQVHVITCTLGEEGEV
Mflv_2165|M.gilvum_PYR-GCK ---METPRLLFVHAHPDDETLTTGATIAHYTARGAEVQVITCTLGEEGEV
MSMEG_5129|M.smegmatis_MC2_155 MSSHESPRLLFVHAHPDDETLTTGGTIAHYVARSAEVHVVTCTLGEEGEV
TH_0660|M.thermoresistible__bu MDPNALPRLLFVHAHPDDETLMTGGTIAHYAARGADVRVVTCTLGEEGEV
Mb1203|M.bovis_AF2122/97 MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEV
Rv1170|M.tuberculosis_H37Rv MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEV
MMAR_4283|M.marinum_M MP--ETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEV
MUL_1017|M.ulcerans_Agy99 MP--ETPRLLFVHAHPDDESLSNGATIAHYAARGAQVHVVTCTLGEEGEV
MLBr_01495|M.leprae_Br4923 MS--ETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVQVVTCTLGEEGEV
MAV_1310|M.avium_104 MA--ETPRLLFVHAHPDDESLGTGATIAHYTAAGADVRVVTCTLGEEGEV
MAB_1316|M.abscessus_ATCC_1997 ---MTTRRLMLVHAHPDDESLTTGGTIARYAAEGADVQLVTCTLGEEGEV
**::********:* .*.***:*.: .*:*:::**********
Mvan_4535|M.vanbaalenii_PYR-1 IGDEWAQLAVDRADQLGGYRIGELTAALAELGVDRPRFLGGAGRWRDSGM
Mflv_2165|M.gilvum_PYR-GCK IGDRWAQLAVDHADQLGGYRIGELTAALAALGVDRPRYLGGAGRWRDSGM
MSMEG_5129|M.smegmatis_MC2_155 IGERYAQLAVDHADQLGGYRIAELTAALQSLGLRGPRYLGGAGHWRDSGM
TH_0660|M.thermoresistible__bu IGDRYARLAVDHADQLGGYRICELTRALEALGVEEPEFLGGAGRWRDSGM
Mb1203|M.bovis_AF2122/97 IGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGM
Rv1170|M.tuberculosis_H37Rv IGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGM
MMAR_4283|M.marinum_M IGDRWAQLAVDHADQLGGYRIGELTAALQRLGVDAPIYLGGAGRWRDSGM
MUL_1017|M.ulcerans_Agy99 IGDRWAQLAVDHADQLGGYRIGELTAALQRLGVDAPIYLGGAGRWRDSGM
MLBr_01495|M.leprae_Br4923 IGDRWAELTVDHADQLGGYRIFELTEALRALGVSAPIYLGGAGRWRDSGM
MAV_1310|M.avium_104 IGERWAELAVDRADQLGGYRIGELTAALRELGVGEPCYLGGAGRWRDSGM
MAB_1316|M.abscessus_ATCC_1997 IGDRWAQLAVDQADQLGGYRIGELSTALRHLGVDGPTFLGGAGRWRDSGM
**:.:*.*:.*:********* **: ** **: * :*****:******
Mvan_4535|M.vanbaalenii_PYR-1 DGTPARQQQRFVDGDFAEQTATLAAAIDELRPHVVVTYDPNGGYGHPDHI
Mflv_2165|M.gilvum_PYR-GCK EGTPARRRERFVDGDVAEQTAVLAAAIDELRPHVVVTYDPNGGYGHPDHI
MSMEG_5129|M.smegmatis_MC2_155 AGTPSRGRQRWVDADLDEAVGALVAVIGEVRPHVVVTYDPNGGYGHPDHI
TH_0660|M.thermoresistible__bu VGTPRRHHPRFIDADIDEAVGALVRIIRRLRPHVVVTYDPNGGYGHPDHI
Mb1203|M.bovis_AF2122/97 AGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHV
Rv1170|M.tuberculosis_H37Rv AGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHV
MMAR_4283|M.marinum_M AGTEQRGRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDGGYGHPDHV
MUL_1017|M.ulcerans_Agy99 AGTEQRSRRRFVDADDREAVGALVAIIRELRPHVVVTYDPDGGYGHPDHV
MLBr_01495|M.leprae_Br4923 RGTAPRRRQRFIDADENEAVGALVAIIRELRPHVVVTYDPHGGYGHPDHV
MAV_1310|M.avium_104 PGTPKRRRQRFIDADEREAVGALVAVIREQRPHVVVGYDPAGGYGHPDHV
MAB_1316|M.abscessus_ATCC_1997 ADTTPLHPRAFAGADLNEAVGALTALIDEHRPHVVVTYDPFGGYGHPDHI
.* : ..* : ...*. * . ****** *** ********:
Mvan_4535|M.vanbaalenii_PYR-1 HAHRVTTAAVA----------------ASTWQVPKLYWTVTSSSALAAAL
Mflv_2165|M.gilvum_PYR-GCK HTHRLTTAAVE----------------AAAWQVPKFYWTVTSDSALRTGI
MSMEG_5129|M.smegmatis_MC2_155 QTHVVTTRAVA-------AAPEAVG-----WTVPKFYWTVTAISAMTAGL
TH_0660|M.thermoresistible__bu QAHRVTTAAVA-------AAGADDGHPDQPWQVPKFYWTVHARSAIDAGL
Mb1203|M.bovis_AF2122/97 HTHTVTTAAVA----AAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGA
Rv1170|M.tuberculosis_H37Rv HTHTVTTAAVA----AAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGA
MMAR_4283|M.marinum_M QAHVVTTAAVA----AAGS-VGDCDYPGDPWVVPKFYWTILGLSAFLAGR
MUL_1017|M.ulcerans_Agy99 QAHVVTTAAVA----AAGS-VGDCDYPGDPWVVPKFYWTVLGVSAFLAGR
MLBr_01495|M.leprae_Br4923 HTHFITAAAVASSGVAAGLEVGADEYPGKPWKVPKFYWSVFALSAFEAGM
MAV_1310|M.avium_104 HVHTVTTAAVA--------AAGAGDFPGEPWAVPKFYWSVFATRPFEAAV
MAB_1316|M.abscessus_ATCC_1997 QAHTVTTAAVE----------------KASWQVAKLYWTVIATSALETGL
:.* :*: ** * *.*:**:: . .: :.
Mvan_4535|M.vanbaalenii_PYR-1 ASMG--AVPEEWIRVSADDLPLFGYSDEAIDAALDLT-AHESARVAALRA
Mflv_2165|M.gilvum_PYR-GCK AALT--DVPDGWVTLTADDLPLVGFTDDTIDAALDLG-AHSAARVAAMHA
MSMEG_5129|M.smegmatis_MC2_155 QALG--DVPSEWIRVNAEDIP-FGFGDDQIDAVVDVT-AELPAKVGAMRA
TH_0660|M.thermoresistible__bu RQLG--DVPADWIRVSIEDVP-FGYPDERIDAVIDTT-ACLPAKIAALKA
Mb1203|M.bovis_AF2122/97 RALVPDDLRPEWVLPRADEIA-FGYSDDGIDAVVEADEQARAAKVAALAA
Rv1170|M.tuberculosis_H37Rv RALVPDDLRPEWVLPRADEIA-FGYSDDGIDAVVEADEQARAAKVAALAA
MMAR_4283|M.marinum_M QALTPDDLLPEWVLP-PEDIP-FIYPDERIDAVVTGDSDARAAKIAALAA
MUL_1017|M.ulcerans_Agy99 QALTPDDLLPEWVLP-PEDIP-FIYPDERIDAVVTGDSDARAAKIAALAA
MLBr_01495|M.leprae_Br4923 NALQGKDLRPEWTIPPREEFY-FGYSDKDIDAVVEATSDVWAAKTAALTA
MAV_1310|M.avium_104 QALTPEDLRPDWSMPSAEQFT-FGYADDHIDAVVAAGPHAWAAKRAALAA
MAB_1316|M.abscessus_ATCC_1997 ASIT--QLPPGCQPAPLDLIP--TFADEKISAAIDVS-GHREAKVAALRA
: : : . : *. *.*.: *: .*: *
Mvan_4535|M.vanbaalenii_PYR-1 HRTQVSVSPDGRSFALSNNVALPVDPTEYYVLAAGSAGARDERGWETDLL
Mflv_2165|M.gilvum_PYR-GCK HQTQITVAPDGRSFALSNDIALPVDATEYYVLARGEAGERDARGWETDLL
MSMEG_5129|M.smegmatis_MC2_155 HATQITVAPDGRAFALSNNIALPVLGEEHYVLVSGEAGPRDSRGWETDLL
TH_0660|M.thermoresistible__bu HATQVTVAPGEQAFTLSNNIAMPILAEEHYILVSGSKGPTDARGFETDLL
Mb1203|M.bovis_AF2122/97 HATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLL
Rv1170|M.tuberculosis_H37Rv HATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLL
MMAR_4283|M.marinum_M HATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGARDERGWETDLL
MUL_1017|M.ulcerans_Agy99 HATQVTVGPSGRACALSNNMALPILADEHYLLVAGRAGARDERGWEIDLL
MLBr_01495|M.leprae_Br4923 HATQVVVGPTGRACALSNNMVMPIFAQEHYVLAAGSAGNRDERGWETDLL
MAV_1310|M.avium_104 HATQVVVGPTGRACALSNNVALPILDEEHYVLVAGAAGARDERGWETDLL
MAB_1316|M.abscessus_ATCC_1997 HATQLTVSDDGSSMALSNLIALPIADIEHFVLVRGEPG--VDTGWESDLF
* **: *. : :*** :.:*: *:::*. * * *:* **:
Mvan_4535|M.vanbaalenii_PYR-1 SGLSVG-----
Mflv_2165|M.gilvum_PYR-GCK AGLNLR-----
MSMEG_5129|M.smegmatis_MC2_155 AGLDLE-----
TH_0660|M.thermoresistible__bu AGLTLD-----
Mb1203|M.bovis_AF2122/97 AGLGFTASGT-
Rv1170|M.tuberculosis_H37Rv AGLGFTASGT-
MMAR_4283|M.marinum_M AGLGFTGFGT-
MUL_1017|M.ulcerans_Agy99 AGLGFTGFGT-
MLBr_01495|M.leprae_Br4923 AGLCLDGFDAR
MAV_1310|M.avium_104 AGLEFGAAPRR
MAB_1316|M.abscessus_ATCC_1997 AGVEL------
:*: .