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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0504 | prcA | - | 100% (250) | proteasome (alpha subunit) PrcA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2133c | prcA | 1e-105 | 81.62% (234) | proteasome (alpha subunit) PrcA |
M. gilvum PYR-GCK | Mflv_3078 | - | 1e-112 | 85.11% (235) | 20S proteasome, A and B subunits |
M. tuberculosis H37Rv | Rv2109c | prcA | 1e-105 | 81.62% (234) | proteasome (alpha subunit) PrcA |
M. leprae Br4923 | MLBr_01323 | prcA | 1e-103 | 76.19% (252) | proteasome alpha-type subunit 1 |
M. abscessus ATCC 19977 | MAB_2173 | - | 8e-90 | 67.33% (251) | proteasome (alpha subunit) PrcA |
M. marinum M | MMAR_3084 | prcA | 1e-104 | 77.11% (249) | proteasome (alpha subunit) PrcA |
M. avium 104 | MAV_2405 | - | 1e-102 | 78.48% (237) | peptidase, T1 family protein |
M. smegmatis MC2 155 | MSMEG_3894 | - | 1e-112 | 82.52% (246) | proteasome alpha subunit |
M. ulcerans Agy99 | MUL_2330 | prcA | 1e-104 | 77.02% (248) | proteasome (alpha subunit) PrcA |
M. vanbaalenii PYR-1 | Mvan_3448 | - | 1e-110 | 84.26% (235) | 20S proteasome, A and B subunits |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3078|M.gilvum_PYR-GCK MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSL Mvan_3448|M.vanbaalenii_PYR-1 MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSL MSMEG_3894|M.smegmatis_MC2_155 MSFPYFISPEQAMRERSELARKGIARGRSVVALAYSEGVLFVAENPSRSL TH_0504|M.thermoresistible__bu VTFPYFISPEQAMRERSELARKGIARGRSVVVLAYADGVLFVAENPSRSL Mb2133c|M.bovis_AF2122/97 MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSL Rv2109c|M.tuberculosis_H37Rv MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSL MLBr_01323|M.leprae_Br4923 MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSL MMAR_3084|M.marinum_M MSFPYFISPEQAMRERSELARKGIARGKSVVALAFAGGVLFVAENPSRSL MUL_2330|M.ulcerans_Agy99 MSFPYFISPEQAMRERSELARKGIARGKSVVALAFAGGVLFVAENPSRSL MAV_2405|M.avium_104 MSFPYFISPEQAMRERSELARKGIARGKSVVALVYAGGVLFVAENPSRSL MAB_2173|M.abscessus_ATCC_1997 MTFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSL ::***: * ** **:*********:*.:**:.*.:: **********.** Mflv_3078|M.gilvum_PYR-GCK QKVSELYDRVGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLA Mvan_3448|M.vanbaalenii_PYR-1 QKVSELYDRIGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLA MSMEG_3894|M.smegmatis_MC2_155 QKVSELYDRVGFAAVGRFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA TH_0504|M.thermoresistible__bu QKVSELYDRVGFAAVGRFNEFNNLRRGGIQFADTQGYAYSRRDVTGRQLA Mb2133c|M.bovis_AF2122/97 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA Rv2109c|M.tuberculosis_H37Rv QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA MLBr_01323|M.leprae_Br4923 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA MMAR_3084|M.marinum_M QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA MUL_2330|M.ulcerans_Agy99 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA MAV_2405|M.avium_104 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA MAB_2173|M.abscessus_ATCC_1997 QKVSEVYDRVGFAAVGKFNEFDRLRRGGIQWADMRGYAYDRRDVSGRQLA **:**:***:****.*:****:.** ***::** :****.****:***** Mflv_3078|M.gilvum_PYR-GCK NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE Mvan_3448|M.vanbaalenii_PYR-1 NVYAQTLGTIFTEQAKPYEVELCVAEVAHHGETKAPELYRITYDGSIADE MSMEG_3894|M.smegmatis_MC2_155 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE TH_0504|M.thermoresistible__bu NVYAQTLGTIFTEQPKPYEVELCIAEVAHYGESKPPELYRITYDGSIADE Mb2133c|M.bovis_AF2122/97 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADE Rv2109c|M.tuberculosis_H37Rv NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADE MLBr_01323|M.leprae_Br4923 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDE MMAR_3084|M.marinum_M NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGESKAPELYRITYDGSIADE MUL_2330|M.ulcerans_Agy99 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE MAV_2405|M.avium_104 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADE MAB_2173|M.abscessus_ATCC_1997 NIYAEALGTIFNEQAKPYEVELCVGEVAHYGRDTEPVLYRITYDGSIADE *:**::*****.**.********:.****:*. . * ********** ** Mflv_3078|M.gilvum_PYR-GCK PHFVVMGGTTEPIATALNESYAENASLEDAVRIAVAALGAGG---NGAEP Mvan_3448|M.vanbaalenii_PYR-1 PHFVVMGGTTEPISTALNESYKENLSLADAVSIAVKALGAGV---NGAEP MSMEG_3894|M.smegmatis_MC2_155 PHFVVMGGTTEPIIAALNESYTENASLQDAVEIAVKALSASA---EGAEP TH_0504|M.thermoresistible__bu PHFVVMGGTTEPIIAALNESYTENADLTTAMRIAVNALQAAP---EGGEQ Mb2133c|M.bovis_AF2122/97 PHFVVMGGTTEPIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQ Rv2109c|M.tuberculosis_H37Rv PHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRAGSADTSGGDQ MLBr_01323|M.leprae_Br4923 PHFMVMGGTTESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQ MMAR_3084|M.marinum_M PHFVVMGGTTEPITTALKNTYTENADLPDALGIAVEALRAGSAENSSNDQ MUL_2330|M.ulcerans_Agy99 PHFVVMGGTTEPITTALKNTYTENADLPDALDIAVEALRAGSAENSSNDQ MAV_2405|M.avium_104 PHFVVMGGTTEPITTALKDSYAENANLREATRIAVRALRAGS-ESSNGDQ MAB_2173|M.abscessus_ATCC_1997 PHWVVMGGNTEPVINSLKESYVEDSALKDAVGFAVKALQAGTAGANGSEG **::****.**.: :*:::* *: * * :** ** *. . : Mflv_3078|M.gilvum_PYR-GCK RTLGPSTLEVAILDANRPRRAFRRITGAALEALLPQADTKDDSQDSEGAA Mvan_3448|M.vanbaalenii_PYR-1 RTLGPATLEVAVLDANRPRRAFRRITGSALEALLPEVDSSESSNEAEAGA MSMEG_3894|M.smegmatis_MC2_155 RSLGPSTLEVAILDAGRPRRAFRRITGAALEALLPEQ-----PQQADSGD TH_0504|M.thermoresistible__bu RVLGPETLEVAVLDATKRRRAFRRLTGSVLEELLPKPDPGTPPQQEPPQP Mb2133c|M.bovis_AF2122/97 PTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQES----------- Rv2109c|M.tuberculosis_H37Rv PTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQES----------- MLBr_01323|M.leprae_Br4923 PTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSKGSKGAQNPKG MMAR_3084|M.marinum_M PVLGVASLEAAILDANKPRRAFRRLTRSTLETLLQERDSKESAESEEPKE MUL_2330|M.ulcerans_Agy99 PVLGVASLEAAILDANKPRRAFRRLTRSTLETLLQERDSKESAESEEPIE MAV_2405|M.avium_104 SALDVGSLEVAILDVNRPRRAFRRINRPTLENLLRELDSNGSDGNGDAPE MAB_2173|M.abscessus_ATCC_1997 RALG--GLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQTEGGGDPA *. **.*:*: : ******: . *: ** . Mflv_3078|M.gilvum_PYR-GCK EPDA------------- Mvan_3448|M.vanbaalenii_PYR-1 EKGSGES---------- MSMEG_3894|M.smegmatis_MC2_155 KPTE------------- TH_0504|M.thermoresistible__bu AR--------------- Mb2133c|M.bovis_AF2122/97 --------PQSDGESSG Rv2109c|M.tuberculosis_H37Rv --------PQSDGESSG MLBr_01323|M.leprae_Br4923 ARDSKN--SKSYGESTD MMAR_3084|M.marinum_M SEEGKKTGKKSDADSSD MUL_2330|M.ulcerans_Agy99 SEEGKKTGKKSDADSSD MAV_2405|M.avium_104 LNGG----------SSD MAB_2173|M.abscessus_ATCC_1997 PESGDSKDAKDN-----