For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0504 (prcA)

annotation: proteasome (alpha subunit) PrcA
coordinates: 1080026 - 1080775
length: 250

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0504prcA-100% (250)proteasome (alpha subunit) PrcA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2133cprcA1e-10581.62% (234) proteasome (alpha subunit) PrcA
M. gilvum PYR-GCKMflv_3078-1e-11285.11% (235) 20S proteasome, A and B subunits
M. tuberculosis H37RvRv2109cprcA1e-10581.62% (234) proteasome (alpha subunit) PrcA
M. leprae Br4923MLBr_01323prcA1e-10376.19% (252) proteasome alpha-type subunit 1
M. abscessus ATCC 19977MAB_2173-8e-9067.33% (251) proteasome (alpha subunit) PrcA
M. marinum MMMAR_3084prcA1e-10477.11% (249) proteasome (alpha subunit) PrcA
M. avium 104MAV_2405-1e-10278.48% (237) peptidase, T1 family protein
M. smegmatis MC2 155MSMEG_3894-1e-11282.52% (246) proteasome alpha subunit
M. ulcerans Agy99MUL_2330prcA1e-10477.02% (248) proteasome (alpha subunit) PrcA
M. vanbaalenii PYR-1Mvan_3448-1e-11084.26% (235) 20S proteasome, A and B subunits

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3078|M.gilvum_PYR-GCK          MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSL
Mvan_3448|M.vanbaalenii_PYR-1       MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSL
MSMEG_3894|M.smegmatis_MC2_155      MSFPYFISPEQAMRERSELARKGIARGRSVVALAYSEGVLFVAENPSRSL
TH_0504|M.thermoresistible__bu      VTFPYFISPEQAMRERSELARKGIARGRSVVVLAYADGVLFVAENPSRSL
Mb2133c|M.bovis_AF2122/97           MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSL
Rv2109c|M.tuberculosis_H37Rv        MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSL
MLBr_01323|M.leprae_Br4923          MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSL
MMAR_3084|M.marinum_M               MSFPYFISPEQAMRERSELARKGIARGKSVVALAFAGGVLFVAENPSRSL
MUL_2330|M.ulcerans_Agy99           MSFPYFISPEQAMRERSELARKGIARGKSVVALAFAGGVLFVAENPSRSL
MAV_2405|M.avium_104                MSFPYFISPEQAMRERSELARKGIARGKSVVALVYAGGVLFVAENPSRSL
MAB_2173|M.abscessus_ATCC_1997      MTFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSL
                                    ::***: * ** **:*********:*.:**:.*.:: **********.**

Mflv_3078|M.gilvum_PYR-GCK          QKVSELYDRVGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLA
Mvan_3448|M.vanbaalenii_PYR-1       QKVSELYDRIGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLA
MSMEG_3894|M.smegmatis_MC2_155      QKVSELYDRVGFAAVGRFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
TH_0504|M.thermoresistible__bu      QKVSELYDRVGFAAVGRFNEFNNLRRGGIQFADTQGYAYSRRDVTGRQLA
Mb2133c|M.bovis_AF2122/97           QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
Rv2109c|M.tuberculosis_H37Rv        QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MLBr_01323|M.leprae_Br4923          QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MMAR_3084|M.marinum_M               QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MUL_2330|M.ulcerans_Agy99           QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MAV_2405|M.avium_104                QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MAB_2173|M.abscessus_ATCC_1997      QKVSEVYDRVGFAAVGKFNEFDRLRRGGIQWADMRGYAYDRRDVSGRQLA
                                    **:**:***:****.*:****:.** ***::** :****.****:*****

Mflv_3078|M.gilvum_PYR-GCK          NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE
Mvan_3448|M.vanbaalenii_PYR-1       NVYAQTLGTIFTEQAKPYEVELCVAEVAHHGETKAPELYRITYDGSIADE
MSMEG_3894|M.smegmatis_MC2_155      NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE
TH_0504|M.thermoresistible__bu      NVYAQTLGTIFTEQPKPYEVELCIAEVAHYGESKPPELYRITYDGSIADE
Mb2133c|M.bovis_AF2122/97           NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADE
Rv2109c|M.tuberculosis_H37Rv        NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADE
MLBr_01323|M.leprae_Br4923          NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDE
MMAR_3084|M.marinum_M               NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGESKAPELYRITYDGSIADE
MUL_2330|M.ulcerans_Agy99           NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE
MAV_2405|M.avium_104                NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADE
MAB_2173|M.abscessus_ATCC_1997      NIYAEALGTIFNEQAKPYEVELCVGEVAHYGRDTEPVLYRITYDGSIADE
                                    *:**::*****.**.********:.****:*. . * ********** **

Mflv_3078|M.gilvum_PYR-GCK          PHFVVMGGTTEPIATALNESYAENASLEDAVRIAVAALGAGG---NGAEP
Mvan_3448|M.vanbaalenii_PYR-1       PHFVVMGGTTEPISTALNESYKENLSLADAVSIAVKALGAGV---NGAEP
MSMEG_3894|M.smegmatis_MC2_155      PHFVVMGGTTEPIIAALNESYTENASLQDAVEIAVKALSASA---EGAEP
TH_0504|M.thermoresistible__bu      PHFVVMGGTTEPIIAALNESYTENADLTTAMRIAVNALQAAP---EGGEQ
Mb2133c|M.bovis_AF2122/97           PHFVVMGGTTEPIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQ
Rv2109c|M.tuberculosis_H37Rv        PHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRAGSADTSGGDQ
MLBr_01323|M.leprae_Br4923          PHFMVMGGTTESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQ
MMAR_3084|M.marinum_M               PHFVVMGGTTEPITTALKNTYTENADLPDALGIAVEALRAGSAENSSNDQ
MUL_2330|M.ulcerans_Agy99           PHFVVMGGTTEPITTALKNTYTENADLPDALDIAVEALRAGSAENSSNDQ
MAV_2405|M.avium_104                PHFVVMGGTTEPITTALKDSYAENANLREATRIAVRALRAGS-ESSNGDQ
MAB_2173|M.abscessus_ATCC_1997      PHWVVMGGNTEPVINSLKESYVEDSALKDAVGFAVKALQAGTAGANGSEG
                                    **::****.**.:  :*:::* *:  *  *  :** ** *.     . : 

Mflv_3078|M.gilvum_PYR-GCK          RTLGPSTLEVAILDANRPRRAFRRITGAALEALLPQADTKDDSQDSEGAA
Mvan_3448|M.vanbaalenii_PYR-1       RTLGPATLEVAVLDANRPRRAFRRITGSALEALLPEVDSSESSNEAEAGA
MSMEG_3894|M.smegmatis_MC2_155      RSLGPSTLEVAILDAGRPRRAFRRITGAALEALLPEQ-----PQQADSGD
TH_0504|M.thermoresistible__bu      RVLGPETLEVAVLDATKRRRAFRRLTGSVLEELLPKPDPGTPPQQEPPQP
Mb2133c|M.bovis_AF2122/97           PTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQES-----------
Rv2109c|M.tuberculosis_H37Rv        PTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQES-----------
MLBr_01323|M.leprae_Br4923          PTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSKGSKGAQNPKG
MMAR_3084|M.marinum_M               PVLGVASLEAAILDANKPRRAFRRLTRSTLETLLQERDSKESAESEEPKE
MUL_2330|M.ulcerans_Agy99           PVLGVASLEAAILDANKPRRAFRRLTRSTLETLLQERDSKESAESEEPIE
MAV_2405|M.avium_104                SALDVGSLEVAILDVNRPRRAFRRINRPTLENLLRELDSNGSDGNGDAPE
MAB_2173|M.abscessus_ATCC_1997      RALG--GLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQTEGGGDPA
                                      *.   **.*:*:  : ******:  . *: ** .              

Mflv_3078|M.gilvum_PYR-GCK          EPDA-------------
Mvan_3448|M.vanbaalenii_PYR-1       EKGSGES----------
MSMEG_3894|M.smegmatis_MC2_155      KPTE-------------
TH_0504|M.thermoresistible__bu      AR---------------
Mb2133c|M.bovis_AF2122/97           --------PQSDGESSG
Rv2109c|M.tuberculosis_H37Rv        --------PQSDGESSG
MLBr_01323|M.leprae_Br4923          ARDSKN--SKSYGESTD
MMAR_3084|M.marinum_M               SEEGKKTGKKSDADSSD
MUL_2330|M.ulcerans_Agy99           SEEGKKTGKKSDADSSD
MAV_2405|M.avium_104                LNGG----------SSD
MAB_2173|M.abscessus_ATCC_1997      PESGDSKDAKDN-----