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SFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEF DNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRI TYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRAGSADTSGGDQPTLGVASLEVA VLDANRPRRAFRRITGSALQALLVDQESPQSDGESSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2109c | prcA | - | 100% (248) | proteasome (alpha subunit) PrcA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2133c | prcA | 1e-136 | 99.19% (248) | proteasome (alpha subunit) PrcA |
| M. gilvum PYR-GCK | Mflv_3078 | - | 1e-112 | 81.85% (248) | 20S proteasome, A and B subunits |
| M. leprae Br4923 | MLBr_01323 | prcA | 1e-123 | 91.39% (244) | proteasome alpha-type subunit 1 |
| M. abscessus ATCC 19977 | MAB_2173 | - | 5e-96 | 71.02% (245) | proteasome (alpha subunit) PrcA |
| M. marinum M | MMAR_3084 | prcA | 1e-117 | 86.78% (242) | proteasome (alpha subunit) PrcA |
| M. avium 104 | MAV_2405 | - | 1e-115 | 86.48% (244) | peptidase, T1 family protein |
| M. smegmatis MC2 155 | MSMEG_3894 | - | 1e-111 | 82.45% (245) | proteasome alpha subunit |
| M. thermoresistible (build 8) | TH_0504 | prcA | 1e-105 | 81.62% (234) | proteasome (alpha subunit) PrcA |
| M. ulcerans Agy99 | MUL_2330 | prcA | 1e-118 | 87.19% (242) | proteasome (alpha subunit) PrcA |
| M. vanbaalenii PYR-1 | Mvan_3448 | - | 1e-110 | 81.30% (246) | 20S proteasome, A and B subunits |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2109c|M.tuberculosis_H37Rv MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSL
Mb2133c|M.bovis_AF2122/97 MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSL
MLBr_01323|M.leprae_Br4923 MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSL
MMAR_3084|M.marinum_M MSFPYFISPEQAMRERSELARKGIARGKSVVALAFAGGVLFVAENPSRSL
MUL_2330|M.ulcerans_Agy99 MSFPYFISPEQAMRERSELARKGIARGKSVVALAFAGGVLFVAENPSRSL
MAV_2405|M.avium_104 MSFPYFISPEQAMRERSELARKGIARGKSVVALVYAGGVLFVAENPSRSL
Mflv_3078|M.gilvum_PYR-GCK MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSL
Mvan_3448|M.vanbaalenii_PYR-1 MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSL
MSMEG_3894|M.smegmatis_MC2_155 MSFPYFISPEQAMRERSELARKGIARGRSVVALAYSEGVLFVAENPSRSL
TH_0504|M.thermoresistible__bu VTFPYFISPEQAMRERSELARKGIARGRSVVVLAYADGVLFVAENPSRSL
MAB_2173|M.abscessus_ATCC_1997 MTFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSL
::***: * ** **:*********:*.:**:.*.:: **********.**
Rv2109c|M.tuberculosis_H37Rv QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
Mb2133c|M.bovis_AF2122/97 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MLBr_01323|M.leprae_Br4923 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MMAR_3084|M.marinum_M QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MUL_2330|M.ulcerans_Agy99 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
MAV_2405|M.avium_104 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
Mflv_3078|M.gilvum_PYR-GCK QKVSELYDRVGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLA
Mvan_3448|M.vanbaalenii_PYR-1 QKVSELYDRIGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLA
MSMEG_3894|M.smegmatis_MC2_155 QKVSELYDRVGFAAVGRFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLA
TH_0504|M.thermoresistible__bu QKVSELYDRVGFAAVGRFNEFNNLRRGGIQFADTQGYAYSRRDVTGRQLA
MAB_2173|M.abscessus_ATCC_1997 QKVSEVYDRVGFAAVGKFNEFDRLRRGGIQWADMRGYAYDRRDVSGRQLA
**:**:***:****.*:****:.** ***::** :****.****:*****
Rv2109c|M.tuberculosis_H37Rv NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADE
Mb2133c|M.bovis_AF2122/97 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADE
MLBr_01323|M.leprae_Br4923 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDE
MMAR_3084|M.marinum_M NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGESKAPELYRITYDGSIADE
MUL_2330|M.ulcerans_Agy99 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE
MAV_2405|M.avium_104 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADE
Mflv_3078|M.gilvum_PYR-GCK NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE
Mvan_3448|M.vanbaalenii_PYR-1 NVYAQTLGTIFTEQAKPYEVELCVAEVAHHGETKAPELYRITYDGSIADE
MSMEG_3894|M.smegmatis_MC2_155 NVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADE
TH_0504|M.thermoresistible__bu NVYAQTLGTIFTEQPKPYEVELCIAEVAHYGESKPPELYRITYDGSIADE
MAB_2173|M.abscessus_ATCC_1997 NIYAEALGTIFNEQAKPYEVELCVGEVAHYGRDTEPVLYRITYDGSIADE
*:**::*****.**.********:.****:*. . * ********** **
Rv2109c|M.tuberculosis_H37Rv PHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRAGSADTSGGDQ
Mb2133c|M.bovis_AF2122/97 PHFVVMGGTTEPIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQ
MLBr_01323|M.leprae_Br4923 PHFMVMGGTTESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQ
MMAR_3084|M.marinum_M PHFVVMGGTTEPITTALKNTYTENADLPDALGIAVEALRAGSAENSSNDQ
MUL_2330|M.ulcerans_Agy99 PHFVVMGGTTEPITTALKNTYTENADLPDALDIAVEALRAGSAENSSNDQ
MAV_2405|M.avium_104 PHFVVMGGTTEPITTALKDSYAENANLREATRIAVRALRAGS-ESSNGDQ
Mflv_3078|M.gilvum_PYR-GCK PHFVVMGGTTEPIATALNESYAENASLEDAVRIAVAALGAGG---NGAEP
Mvan_3448|M.vanbaalenii_PYR-1 PHFVVMGGTTEPISTALNESYKENLSLADAVSIAVKALGAGV---NGAEP
MSMEG_3894|M.smegmatis_MC2_155 PHFVVMGGTTEPIIAALNESYTENASLQDAVEIAVKALSASA---EGAEP
TH_0504|M.thermoresistible__bu PHFVVMGGTTEPIIAALNESYTENADLTTAMRIAVNALQAAP---EGGEQ
MAB_2173|M.abscessus_ATCC_1997 PHWVVMGGNTEPVINSLKESYVEDSALKDAVGFAVKALQAGTAGANGSEG
**::****.**.: :*:::* *: * * :** ** *. . :
Rv2109c|M.tuberculosis_H37Rv PTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQES-----------
Mb2133c|M.bovis_AF2122/97 PTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQES-----------
MLBr_01323|M.leprae_Br4923 PTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSKGSKGAQNPKG
MMAR_3084|M.marinum_M PVLGVASLEAAILDANKPRRAFRRLTRSTLETLLQERDSKESAESEEPKE
MUL_2330|M.ulcerans_Agy99 PVLGVASLEAAILDANKPRRAFRRLTRSTLETLLQERDSKESAESEEPIE
MAV_2405|M.avium_104 SALDVGSLEVAILDVNRPRRAFRRINRPTLENLLRELDSNGSDGNGDAPE
Mflv_3078|M.gilvum_PYR-GCK RTLGPSTLEVAILDANRPRRAFRRITGAALEALLPQADTKDDSQDSEGAA
Mvan_3448|M.vanbaalenii_PYR-1 RTLGPATLEVAVLDANRPRRAFRRITGSALEALLPEVDSSESSNEAEAGA
MSMEG_3894|M.smegmatis_MC2_155 RSLGPSTLEVAILDAGRPRRAFRRITGAALEALLPEQ-----PQQADSGD
TH_0504|M.thermoresistible__bu RVLGPETLEVAVLDATKRRRAFRRLTGSVLEELLPKPDPGTPPQQEPPQP
MAB_2173|M.abscessus_ATCC_1997 RALG--GLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQTEGGGDPA
*. **.*:*: : ******: . *: ** .
Rv2109c|M.tuberculosis_H37Rv --------PQSDGESSG
Mb2133c|M.bovis_AF2122/97 --------PQSDGESSG
MLBr_01323|M.leprae_Br4923 ARDSKN--SKSYGESTD
MMAR_3084|M.marinum_M SEEGKKTGKKSDADSSD
MUL_2330|M.ulcerans_Agy99 SEEGKKTGKKSDADSSD
MAV_2405|M.avium_104 LNGG----------SSD
Mflv_3078|M.gilvum_PYR-GCK EPDA-------------
Mvan_3448|M.vanbaalenii_PYR-1 EKGSGES----------
MSMEG_3894|M.smegmatis_MC2_155 KPTE-------------
TH_0504|M.thermoresistible__bu AR---------------
MAB_2173|M.abscessus_ATCC_1997 PESGDSKDAKDN-----