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M. thermoresistible (build 8) TH_0493 (-)

annotation: conserved membrane protein
coordinates: 1062267 - 1064021
length: 585

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0493--100% (585)conserved membrane protein
M. thermoresistible (build 8)TH_4039-e-11540.65% (583) PUTATIVE conserved hypothetical membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1163-0.074.56% (574) hypothetical protein Mb1163
M. gilvum PYR-GCKMflv_2113-0.078.15% (572) hypothetical protein Mflv_2113
M. tuberculosis H37RvRv1132-0.074.56% (574) hypothetical protein Rv1132
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4552-0.075.09% (574) hypothetical protein MAB_4552
M. marinum MMMAR_4329-0.075.39% (573) hypothetical protein MMAR_4329
M. avium 104MAV_1261-0.076.12% (578) hypothetical protein MAV_1261
M. smegmatis MC2 155MSMEG_5202-0.076.75% (585) hypothetical protein MSMEG_5202
M. ulcerans Agy99MUL_0139-0.075.39% (573) hypothetical protein MUL_0139
M. vanbaalenii PYR-1Mvan_4591-0.079.37% (572) hypothetical protein Mvan_4591

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2113|M.gilvum_PYR-GCK          ----MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVIHLF
Mvan_4591|M.vanbaalenii_PYR-1       ----MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVLHLF
MSMEG_5202|M.smegmatis_MC2_155      ----MGFLKQTAPQVDFEEWSKGTRAEKIRPMARHWAEVGFGTPVALHLF
TH_0493|M.thermoresistible__bu      ----MGFLKQNTPVVDYEQWRTGTRAEKIKPMARHWAEVGFGTPVALHLF
MAB_4552|M.abscessus_ATCC_1997      ----MGFLKPTLPVVDVADWGKGTRAEKIRPMARHWAEVGFGTPVALHLF
Mb1163|M.bovis_AF2122/97            ----MGFLQPRLPDIDLAEWSQGSRSQKIRPMAQHWAEVGFGTPVLLHLF
Rv1132|M.tuberculosis_H37Rv         ----MGFLQPRLPDIDLAEWSQGSRSQKIRPMAQHWAEVGFGTPVLLHLF
MMAR_4329|M.marinum_M               MCETMGFLKPVLPQVDIVEWGKGTRSEKIRPMARHWAEVGFGTPVVMHLF
MUL_0139|M.ulcerans_Agy99           ----MGFLKPVLPQVDIVEWGKGTRSEKIRPMARHWAEVGFGTPVVMHLF
MAV_1261|M.avium_104                ----MGFLKPELPQLDMAEWNKGTRSDKIRPMAKHWAEVGFGTPVALHLF
                                        ****:   * :*  :*  *:*:::* ***:*********** :***

Mflv_2113|M.gilvum_PYR-GCK          YVVKILLYVLVAWLIVLS-TSGIDGFTDVAAWYHEPIVYQKVVFYTMLFE
Mvan_4591|M.vanbaalenii_PYR-1       YVVKILLYILVAWLIVLT-TSGIDGFTNVAAWYHEPIVYQKVVFYTMLFE
MSMEG_5202|M.smegmatis_MC2_155      YVVKICLYVLGAWLVVLS-TRGIDGFTAVADWWTEPIVFEKVVLYTMLYE
TH_0493|M.thermoresistible__bu      YVLKIGLYILGAWLIAAA-TPGIGGLTDVADWWSEPIVFQKVVLYTMLFE
MAB_4552|M.abscessus_ATCC_1997      YVLKIALYILGGWLFAMVTTEGIDRWTDFS----LPIVFQKVVLYTMLFE
Mb1163|M.bovis_AF2122/97            YVAKILLYVLVGWLIVLT-TKGIDGFTDAAAWYAEPIVFEKVVLYTMLFE
Rv1132|M.tuberculosis_H37Rv         YVAKILLYVLVGWLIVLT-TKGIDGFTDAAAWYAEPIVFEKVVLYTMLFE
MMAR_4329|M.marinum_M               YVGKILLYILVGWLIVFS-TKGIEGFTDVKSWYTEPIVFQKVVLYTMLFE
MUL_0139|M.ulcerans_Agy99           YVGKILLYILVGWLIVFS-TKGIEGFTDVKSWYTEPIVFQKVVLYTMLFE
MAV_1261|M.avium_104                YVVKILLYILGGWLFASA-TRGLGGFTHVASWWSEPIVFEKVVLYTMLFE
                                    ** ** **:* .**..   * *:   *        ***::***:****:*

Mflv_2113|M.gilvum_PYR-GCK          VVGLGCGFGPLNNRFFPPMGSVLYWLRPRTIRLPPWPNRVPLTAGDTRTP
Mvan_4591|M.vanbaalenii_PYR-1       VVGLGCGFGPLNNRFFPPMGSILYWLRPRTIRLPPWPNRVPLTAGDSRTP
MSMEG_5202|M.smegmatis_MC2_155      VVGLGCGFGPLNNRFFPPMGSILYWLRPKTIRLPPWPDRVPLTKGDTRTV
TH_0493|M.thermoresistible__bu      VVGLGCGFGPLNNRFFPPMGSILYWLRPNTIRLPPWPNRIPFTRGTTRTP
MAB_4552|M.abscessus_ATCC_1997      VVGLGCGFGPLNNRFFPPLGSILYWLRPNTIRLPPWP-RIPLTKGSARTA
Mb1163|M.bovis_AF2122/97            VIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPWTRGTKRKP
Rv1132|M.tuberculosis_H37Rv         VIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPWTRGTKRKP
MMAR_4329|M.marinum_M               VVGLGCGFGPLNNRFFPPMGSSLYWLRFGTIRLPPWPERVPWTAGTKRKP
MUL_0139|M.ulcerans_Agy99           VVGLGCGFGPLNNRFFPPMGSSLYWLRFGTIRLPPWPERVPWTAGTKRKP
MAV_1261|M.avium_104                VIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPFTAGTKRKP
                                    *:****************:** ***:*  ******** *:* * *  *. 

Mflv_2113|M.gilvum_PYR-GCK          VDVVLYAALLAVLVIALFSDGTGPIPEIGSEVGVLPVWQTATIIGLLVVA
Mvan_4591|M.vanbaalenii_PYR-1       FDVLLYAALLVMLLFALFSDGTGPIPELGSEVGVLPVWQTATIIGLLVVA
MSMEG_5202|M.smegmatis_MC2_155      FDAVLYGALLVVLLIAIFSDGTGPLPALGTEIGVLPMWQIAAVLVLLAVL
TH_0493|M.thermoresistible__bu      VDVALYGALLVMLVVALASGGTGPVEALGTDIGLLPAWQIWAVLGLLAAA
MAB_4552|M.abscessus_ATCC_1997      VDIALYAAFLGMVLVALLSQPT--------AAGLLPTWQTAAILGLLVIT
Mb1163|M.bovis_AF2122/97            VDVALYALLVMMLLSALFTDGAGPIPELGTMVGLLPAWQIVLILLLLGVL
Rv1132|M.tuberculosis_H37Rv         VDVALYALLVMMLLSALFTDGAGPIPELGTTVGLLPAWQIVLILLLLGVL
MMAR_4329|M.marinum_M               VDVALYALLLIMLVTALFTDGSGPMPELGSKVGLLPMWEIVMILLLLAMV
MUL_0139|M.ulcerans_Agy99           VDVALYALLLIMLVTALFTDGSGPMPELGSKVGLLPMWEIVMILLLLAMV
MAV_1261|M.avium_104                VDVALYALFLLLTLAALFADGTGPVPELGTTIGLLPAWKIVLILLVLAVL
                                    .*  **. :: : : *: :  :          *:** *:   :: :*   

Mflv_2113|M.gilvum_PYR-GCK          GLRDKVIFLAARGEVYGSLAVCFLFS---GADIIIAAKLVCLTIWIGAAT
Mvan_4591|M.vanbaalenii_PYR-1       GLRDKVIFLAARGEVYGSLAVCFLFS---GADIIIAAKLVCLVIWLGAAT
MSMEG_5202|M.smegmatis_MC2_155      GLRDKVIFLAARGEVYASFTVAFLFAG-HGVDAILAAKLVCMVIWLGAAT
TH_0493|M.thermoresistible__bu      GLRDKVIFLAARGEVYASLTVTFLFA---GPDMIVAAKIVFLIIWLGAGV
MAB_4552|M.abscessus_ATCC_1997      GLRDKVIFLAARGEVYGALTVAFLFT---GADMIMAAKLIFMVIWIGAAT
Mb1163|M.bovis_AF2122/97            GLRDKVIFLAARGEVYATLTVTFLFGRLNGIDMIVAAKLVFLVIWIGAAT
Rv1132|M.tuberculosis_H37Rv         GLRDKVIFLAARGEVYATLTVTFLFGRLNGIDMIVAAKLVFLVIWIGAAT
MMAR_4329|M.marinum_M               GLRDKVIFLAARGEVYGTLTVTFLLG---GIDMIVAAKLVFLVIWMGAAT
MUL_0139|M.ulcerans_Agy99           GLRDKVIFLAARGEVYGTLTVTFLLG---GIDMIVAAKLVFLVIWMGAAT
MAV_1261|M.avium_104                GLRDKVIFLAARGEVYASMAVTFLFG---APDMIVGSKVVFLVIWMGAAT
                                    ****************.:::* **:    . * *:.:*:: : **:**..

Mflv_2113|M.gilvum_PYR-GCK          SKLNKHFPFVISTMMSNNPVIRPRSIKRKFFEHFPDDLRPGRASRVLAHF
Mvan_4591|M.vanbaalenii_PYR-1       SKLNKHFPFVISTMMSNNPVMRPRWIKRKFFEHFPDDLRPGRASRFLAHF
MSMEG_5202|M.smegmatis_MC2_155      SKLNKHFPFVISTMMSNNPVLRPRFIKRKFFEHFPDDLRPGRPSRWLAHV
TH_0493|M.thermoresistible__bu      SKLNRHFPFVISTMMSNNPVFRPRWIKRRFFERFPDDLRPGRASRWLAHL
MAB_4552|M.abscessus_ATCC_1997      SKLNRHFPFVISTMMSNNPLIRARRLKRAFFEKFPDDLRPGRLSRVVAHV
Mb1163|M.bovis_AF2122/97            SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFKKFPGDLRPGLLSRIVAHV
Rv1132|M.tuberculosis_H37Rv         SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFKKFPGDLRPGLLSRIVAHV
MMAR_4329|M.marinum_M               SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFAKFPDDLRPGLLSRMLAHL
MUL_0139|M.ulcerans_Agy99           SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFAKFPDDLRPGLLSRMLAHL
MAV_1261|M.avium_104                SKLNKHFPFVISTMMSNNPLVRPRWLKRRFFEKFPDDLRPGRLSRWIAHL
                                    ****:**************:.*.* :** ** :**.*****  ** :**.

Mflv_2113|M.gilvum_PYR-GCK          STAIEMLVPLVLFFSHGGWPTAIAAFVMLVFHFGILSAIPMGVPLEWNVF
Mvan_4591|M.vanbaalenii_PYR-1       STAIEGLVPLVLFFSHGGWATAIAAFVMLVFHFGILSAIPMGVPLEWNVF
MSMEG_5202|M.smegmatis_MC2_155      STAIEMLVPLALFFSHGGWPTALAATVMICFHFGILSAIPMGVPLEWNVF
TH_0493|M.thermoresistible__bu      ATAIELLVPLVLFFSHGGWATAIAAGVMVLFHFGILSAIPMGVPLEWNVF
MAB_4552|M.abscessus_ATCC_1997      STAVEGLVPFALFFSHGGWVTTVAAGVMVCFHLGILTAIPMGVPLEWNVF
Mb1163|M.bovis_AF2122/97            STVIEMCVPVVLFVAHGGWPTVVAATIMVCFHLGILTAIPMGVPLEWNVF
Rv1132|M.tuberculosis_H37Rv         STVIEMCVPVVLFVAHGGWPTVVAATIMVCFHLGILTAIPMGVPLEWNVF
MMAR_4329|M.marinum_M               STFIEMFVPVALFLSHGGWPTTAAAIAMVCFHLGILTAIPMGVPLEWNVF
MUL_0139|M.ulcerans_Agy99           STFIEMFVPVALFLSHGGWPTTAAAIAMVCFHLGILTAIPMGVPLEWNVF
MAV_1261|M.avium_104                STAIEMLVPLPLFFCHGGWPVTVAAVVMVCFHLGILVSIPMGVPLEWNVF
                                    :* :*  **. **..**** .. **  *: **:*** :************

Mflv_2113|M.gilvum_PYR-GCK          MMFSVLALFVGNAGIGLGDLQSPWPIVLFAVVAG-TVVIGNLFPRKVSFL
Mvan_4591|M.vanbaalenii_PYR-1       MMFSVLALFVGNAGIGLADLQSPWPILLFAAVAG-TVVIGNLFPRKVSFL
MSMEG_5202|M.smegmatis_MC2_155      MIFCVATLFVGHADVGITDLSTPLPLLLLAVLVT-TVTLGNLFPRKISFL
TH_0493|M.thermoresistible__bu      MIFGVLWLFVTHAQFGLADVGNPWPVAALSLVLAGTVVLGNLFPHKVSFL
MAB_4552|M.abscessus_ATCC_1997      MIFGVLALFVSHANVGLSDMQHPAPVLLLLAVSAGVVATGNLLPRKVSFL
Mb1163|M.bovis_AF2122/97            MIFGVLSLFVGHACLGLADVKNPVPLAILIAVVAGIVIAGNVFPRKISFL
Rv1132|M.tuberculosis_H37Rv         MIFGVLSLFVGHACLGLADVKNPVPLAILIAVVAGIVIAGNVFPRKISFL
MMAR_4329|M.marinum_M               MIFGVLALFVGHADLGLTDVKSPVPVAILFAVVAGIVILGNLFPRKISFL
MUL_0139|M.ulcerans_Agy99           MIFGVLALFVGHADLGLTDVKSPVPVAILFAVVAGIVILGNLFPRKISFL
MAV_1261|M.avium_104                MIFGVLSLFVAHTGIGLGDLRHPVVVAVLFVVIAGIVVLGNMFPRKISFL
                                    *:* *  *** :: .*: *:  *  :  :  :    *  **::*:*:***

Mflv_2113|M.gilvum_PYR-GCK          PGMRYYAGNWDTTLWCVKPSASEKITSGIVAIASMPAAQMEKFYGSKETA
Mvan_4591|M.vanbaalenii_PYR-1       PGMRYYAGNWDTTLWCVKPSAAEKIANGIVAIASMPAAQMEKFYGSKETA
MSMEG_5202|M.smegmatis_MC2_155      PGMRYYAGNWDTSLWCVKPSAAEKIEKNIVAIASMPAAQMERYYGSPETA
TH_0493|M.thermoresistible__bu      PGMRYYAGNWDTTLWCVKPSAEEKINNGIVAIASMPAAQMERYYGSKETA
MAB_4552|M.abscessus_ATCC_1997      PGMRYYAGNWDTTLWCIKPSASAKIEKGIVAIASMPQAQMERYYGSKDAA
Mb1163|M.bovis_AF2122/97            AAMRYYAGNWDTTLWCIKPSAEDKINRGIVAIASMPAAQLERFYGK-DRA
Rv1132|M.tuberculosis_H37Rv         AAMRYYAGNWDTTLWCIKPSAEDKINRGIVAIASMPAAQLERFYGK-DRA
MMAR_4329|M.marinum_M               PGMRYYAGNWDTTLWCIKPSADAKIKRGIVAIASMPQAQLERFYGK-DRA
MUL_0139|M.ulcerans_Agy99           PGMRYYAGNWDTTLWCIKPSADAKIKRGIVAIASMPQAQLERFYGK-DRA
MAV_1261|M.avium_104                PGMRYYAGNWDTTLWCIKPSASEKISRGIVAIASMPQAQLERFYGSPEAA
                                    ..**********:***:****  **  .******** **:*::**. : *

Mflv_2113|M.gilvum_PYR-GCK          EMYQYMGYAFRSFNTHGRAMFTLAHRAMAGQDEGEYVLTDGERICSTAIG
Mvan_4591|M.vanbaalenii_PYR-1       EVYQYMGYAFRSFNTHGRAMFTLAHRAMADGSEDDYVLTDGERICSTAIG
MSMEG_5202|M.smegmatis_MC2_155      QMYLYMGYAFRGFNSHGRALFTLAHRAMAGHDEGEYVLTDGERIVSTAIG
TH_0493|M.thermoresistible__bu      EMYLYMGYAFRAFNTHGKALFTLAHRAMAGHDEDDYTIIDGERICSTAIG
MAB_4552|M.abscessus_ATCC_1997      QIYMYIGYAFRAMNTHGRAMFTLAHRAMAGQDESEYVITDGERICSTAIG
Mb1163|M.bovis_AF2122/97            QIPMYLGYAFRAMNSHGRALFTLAHRAMAGHDEDDYVITDGERVCSTAVG
Rv1132|M.tuberculosis_H37Rv         QIPMYLGYAFRAMNSHGRALFTLAHRAMAGHDEDDYVITDGERVCSTAVG
MMAR_4329|M.marinum_M               QIPMYLGYAFRAMNTHGRALFTLAHRAMAGQDEDDYVITDGERICSTAVG
MUL_0139|M.ulcerans_Agy99           QIPMYLGYAFRAMNTHGRALFTLAHRAMAGQDEDDYVITDGERICSTAVG
MAV_1261|M.avium_104                QIPLYMGYAFRGFNTHGRALFTLAHRAMAGQNEDDYVITDGERICSTAIG
                                    ::  *:*****.:*:**:*:*********. .*.:*.: ****: ***:*

Mflv_2113|M.gilvum_PYR-GCK          WNFGDGHMHNEQLITALQKRCRFEPGEVRVLILDAQPIHKQRQEYRLVDA
Mvan_4591|M.vanbaalenii_PYR-1       WNFGDGHMHNEQLIAALQKRCQFEPGEVRVLLLDAQPIHRQRQEYRLVDA
MSMEG_5202|M.smegmatis_MC2_155      WNFGDGHMSNEQLVDALQKRCHFEPGEVRIVMLDAQPIQRQTQNYRLVDA
TH_0493|M.thermoresistible__bu      WNFGDGHMHNEQLIEAMQQRCGFEPGEVRVVLLDAQPIHRQTQQYRLVDA
MAB_4552|M.abscessus_ATCC_1997      WNFGDGHMHNEQLIAAMQERCHFEPGEVRIVLLDAQPIHRQTQRYRLVDA
Mb1163|M.bovis_AF2122/97            WNFGDGHLHNEQLIAAMQQRCGFQPGEVRVVLLDAQPIHRQTQEYRLVDA
Rv1132|M.tuberculosis_H37Rv         WNFGDGHLHNEQLIAAMQQRCGFQPGEVRVVLLDAQPIHRQTQEYRLVDA
MMAR_4329|M.marinum_M               WNFGDGHMHNEQLIAAMQQRCNFEPGEVRIVLLDAQPIHKQTQAYRLVDA
MUL_0139|M.ulcerans_Agy99           WNFGDGHMHNEQLIAAMQQRCNFEPGEVRIVLLDAQPIHKQTQAYRLVDA
MAV_1261|M.avium_104                WNFGDGHMHNEQLIAALQERCHFEPGEVRVVLLDAQPIHKQTQAYRLVDA
                                    *******: ****: *:*:** *:*****:::******::* * ******

Mflv_2113|M.gilvum_PYR-GCK          ATGEFERGYVMVADMVTRQPWDDTVPVHVTWQKSG-------
Mvan_4591|M.vanbaalenii_PYR-1       ATGEFERGYVMVADMVTRQPWDDTVPVHVTWRR---------
MSMEG_5202|M.smegmatis_MC2_155      ATGEFERGYVKVADMVTRQPWDDDVPVHGVHSLSGERREHA-
TH_0493|M.thermoresistible__bu      ATGEFERGYVRVADMVVRQPWDDTVPVHVTSSTLPTDRDSAR
MAB_4552|M.abscessus_ATCC_1997      ATGEFESGYVRVADMVNRQPWDDELPVQVNS-----------
Mb1163|M.bovis_AF2122/97            ATGEFERGYVRVADMVNRQPWDDDVPVHVLPG----------
Rv1132|M.tuberculosis_H37Rv         ATGEFERGYVRVADMVNRQPWDDDVPVHVLPG----------
MMAR_4329|M.marinum_M               ATGEFERGWVRVSDMVTRQPWADDVPVQVQSE----------
MUL_0139|M.ulcerans_Agy99           ATGEFERGWVRVSDMVTRQPWADDVPVQVQSE----------
MAV_1261|M.avium_104                ATGEFERGIVRVADMVVRQPWDDDVPVQVVSDDAPSVTPE--
                                    ****** * * *:*** **** * :**: