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MGFLQPRLPDIDLAEWSQGSRSQKIRPMAQHWAEVGFGTPVLLHLFYVAKILLYVLVGWLIVLTTKGIDG FTDAAAWYAEPIVFEKVVLYTMLFEVIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPWTRG TKRKPVDVALYALLVMMLLSALFTDGAGPIPELGTTVGLLPAWQIVLILLLLGVLGLRDKVIFLAARGEV YATLTVTFLFGRLNGIDMIVAAKLVFLVIWIGAATSKLNRHFPFVISTMMSNNPLFRPRFIKRMFFKKFP GDLRPGLLSRIVAHVSTVIEMCVPVVLFVAHGGWPTVVAATIMVCFHLGILTAIPMGVPLEWNVFMIFGV LSLFVGHACLGLADVKNPVPLAILIAVVAGIVIAGNVFPRKISFLAAMRYYAGNWDTTLWCIKPSAEDKI NRGIVAIASMPAAQLERFYGKDRAQIPMYLGYAFRAMNSHGRALFTLAHRAMAGHDEDDYVITDGERVCS TAVGWNFGDGHLHNEQLIAAMQQRCGFQPGEVRVVLLDAQPIHRQTQEYRLVDAATGEFERGYVRVADMV NRQPWDDDVPVHVLPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1132 | - | - | 100% (576) | hypothetical protein Rv1132 |
| M. tuberculosis H37Rv | Rv1431 | - | e-150 | 47.95% (586) | hypothetical protein Rv1431 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1163 | - | 0.0 | 99.83% (576) | hypothetical protein Mb1163 |
| M. gilvum PYR-GCK | Mflv_2113 | - | 0.0 | 72.82% (574) | hypothetical protein Mflv_2113 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4552 | - | 0.0 | 72.87% (575) | hypothetical protein MAB_4552 |
| M. marinum M | MMAR_4329 | - | 0.0 | 84.29% (573) | hypothetical protein MMAR_4329 |
| M. avium 104 | MAV_1261 | - | 0.0 | 78.61% (575) | hypothetical protein MAV_1261 |
| M. smegmatis MC2 155 | MSMEG_5202 | - | 0.0 | 72.43% (573) | hypothetical protein MSMEG_5202 |
| M. thermoresistible (build 8) | TH_0493 | - | 0.0 | 74.56% (574) | conserved membrane protein |
| M. ulcerans Agy99 | MUL_0139 | - | 0.0 | 84.29% (573) | hypothetical protein MUL_0139 |
| M. vanbaalenii PYR-1 | Mvan_4591 | - | 0.0 | 73.52% (574) | hypothetical protein Mvan_4591 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2113|M.gilvum_PYR-GCK ----MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVIHLF
Mvan_4591|M.vanbaalenii_PYR-1 ----MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVLHLF
MSMEG_5202|M.smegmatis_MC2_155 ----MGFLKQTAPQVDFEEWSKGTRAEKIRPMARHWAEVGFGTPVALHLF
TH_0493|M.thermoresistible__bu ----MGFLKQNTPVVDYEQWRTGTRAEKIKPMARHWAEVGFGTPVALHLF
MAB_4552|M.abscessus_ATCC_1997 ----MGFLKPTLPVVDVADWGKGTRAEKIRPMARHWAEVGFGTPVALHLF
Rv1132|M.tuberculosis_H37Rv ----MGFLQPRLPDIDLAEWSQGSRSQKIRPMAQHWAEVGFGTPVLLHLF
Mb1163|M.bovis_AF2122/97 ----MGFLQPRLPDIDLAEWSQGSRSQKIRPMAQHWAEVGFGTPVLLHLF
MMAR_4329|M.marinum_M MCETMGFLKPVLPQVDIVEWGKGTRSEKIRPMARHWAEVGFGTPVVMHLF
MUL_0139|M.ulcerans_Agy99 ----MGFLKPVLPQVDIVEWGKGTRSEKIRPMARHWAEVGFGTPVVMHLF
MAV_1261|M.avium_104 ----MGFLKPELPQLDMAEWNKGTRSDKIRPMAKHWAEVGFGTPVALHLF
****: * :* :* *:*:::* ***:*********** :***
Mflv_2113|M.gilvum_PYR-GCK YVVKILLYVLVAWLIVLS-TSGIDGFTDVAAWYHEPIVYQKVVFYTMLFE
Mvan_4591|M.vanbaalenii_PYR-1 YVVKILLYILVAWLIVLT-TSGIDGFTNVAAWYHEPIVYQKVVFYTMLFE
MSMEG_5202|M.smegmatis_MC2_155 YVVKICLYVLGAWLVVLS-TRGIDGFTAVADWWTEPIVFEKVVLYTMLYE
TH_0493|M.thermoresistible__bu YVLKIGLYILGAWLIAAA-TPGIGGLTDVADWWSEPIVFQKVVLYTMLFE
MAB_4552|M.abscessus_ATCC_1997 YVLKIALYILGGWLFAMVTTEGIDRWTDFS----LPIVFQKVVLYTMLFE
Rv1132|M.tuberculosis_H37Rv YVAKILLYVLVGWLIVLT-TKGIDGFTDAAAWYAEPIVFEKVVLYTMLFE
Mb1163|M.bovis_AF2122/97 YVAKILLYVLVGWLIVLT-TKGIDGFTDAAAWYAEPIVFEKVVLYTMLFE
MMAR_4329|M.marinum_M YVGKILLYILVGWLIVFS-TKGIEGFTDVKSWYTEPIVFQKVVLYTMLFE
MUL_0139|M.ulcerans_Agy99 YVGKILLYILVGWLIVFS-TKGIEGFTDVKSWYTEPIVFQKVVLYTMLFE
MAV_1261|M.avium_104 YVVKILLYILGGWLFASA-TRGLGGFTHVASWWSEPIVFEKVVLYTMLFE
** ** **:* .**.. * *: * ***::***:****:*
Mflv_2113|M.gilvum_PYR-GCK VVGLGCGFGPLNNRFFPPMGSVLYWLRPRTIRLPPWPNRVPLTAGDTRTP
Mvan_4591|M.vanbaalenii_PYR-1 VVGLGCGFGPLNNRFFPPMGSILYWLRPRTIRLPPWPNRVPLTAGDSRTP
MSMEG_5202|M.smegmatis_MC2_155 VVGLGCGFGPLNNRFFPPMGSILYWLRPKTIRLPPWPDRVPLTKGDTRTV
TH_0493|M.thermoresistible__bu VVGLGCGFGPLNNRFFPPMGSILYWLRPNTIRLPPWPNRIPFTRGTTRTP
MAB_4552|M.abscessus_ATCC_1997 VVGLGCGFGPLNNRFFPPLGSILYWLRPNTIRLPPWP-RIPLTKGSARTA
Rv1132|M.tuberculosis_H37Rv VIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPWTRGTKRKP
Mb1163|M.bovis_AF2122/97 VIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPWTRGTKRKP
MMAR_4329|M.marinum_M VVGLGCGFGPLNNRFFPPMGSSLYWLRFGTIRLPPWPERVPWTAGTKRKP
MUL_0139|M.ulcerans_Agy99 VVGLGCGFGPLNNRFFPPMGSSLYWLRFGTIRLPPWPERVPWTAGTKRKP
MAV_1261|M.avium_104 VIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPFTAGTKRKP
*:****************:** ***:* ******** *:* * * *.
Mflv_2113|M.gilvum_PYR-GCK VDVVLYAALLAVLVIALFSDGTGPIPEIGSEVGVLPVWQTATIIGLLVVA
Mvan_4591|M.vanbaalenii_PYR-1 FDVLLYAALLVMLLFALFSDGTGPIPELGSEVGVLPVWQTATIIGLLVVA
MSMEG_5202|M.smegmatis_MC2_155 FDAVLYGALLVVLLIAIFSDGTGPLPALGTEIGVLPMWQIAAVLVLLAVL
TH_0493|M.thermoresistible__bu VDVALYGALLVMLVVALASGGTGPVEALGTDIGLLPAWQIWAVLGLLAAA
MAB_4552|M.abscessus_ATCC_1997 VDIALYAAFLGMVLVALLSQPT--------AAGLLPTWQTAAILGLLVIT
Rv1132|M.tuberculosis_H37Rv VDVALYALLVMMLLSALFTDGAGPIPELGTTVGLLPAWQIVLILLLLGVL
Mb1163|M.bovis_AF2122/97 VDVALYALLVMMLLSALFTDGAGPIPELGTMVGLLPAWQIVLILLLLGVL
MMAR_4329|M.marinum_M VDVALYALLLIMLVTALFTDGSGPMPELGSKVGLLPMWEIVMILLLLAMV
MUL_0139|M.ulcerans_Agy99 VDVALYALLLIMLVTALFTDGSGPMPELGSKVGLLPMWEIVMILLLLAMV
MAV_1261|M.avium_104 VDVALYALFLLLTLAALFADGTGPVPELGTTIGLLPAWKIVLILLVLAVL
.* **. :: : : *: : : *:** *: :: :*
Mflv_2113|M.gilvum_PYR-GCK GLRDKVIFLAARGEVYGSLAVCFLFS---GADIIIAAKLVCLTIWIGAAT
Mvan_4591|M.vanbaalenii_PYR-1 GLRDKVIFLAARGEVYGSLAVCFLFS---GADIIIAAKLVCLVIWLGAAT
MSMEG_5202|M.smegmatis_MC2_155 GLRDKVIFLAARGEVYASFTVAFLFAG-HGVDAILAAKLVCMVIWLGAAT
TH_0493|M.thermoresistible__bu GLRDKVIFLAARGEVYASLTVTFLFA---GPDMIVAAKIVFLIIWLGAGV
MAB_4552|M.abscessus_ATCC_1997 GLRDKVIFLAARGEVYGALTVAFLFT---GADMIMAAKLIFMVIWIGAAT
Rv1132|M.tuberculosis_H37Rv GLRDKVIFLAARGEVYATLTVTFLFGRLNGIDMIVAAKLVFLVIWIGAAT
Mb1163|M.bovis_AF2122/97 GLRDKVIFLAARGEVYATLTVTFLFGRLNGIDMIVAAKLVFLVIWIGAAT
MMAR_4329|M.marinum_M GLRDKVIFLAARGEVYGTLTVTFLLG---GIDMIVAAKLVFLVIWMGAAT
MUL_0139|M.ulcerans_Agy99 GLRDKVIFLAARGEVYGTLTVTFLLG---GIDMIVAAKLVFLVIWMGAAT
MAV_1261|M.avium_104 GLRDKVIFLAARGEVYASMAVTFLFG---APDMIVGSKVVFLVIWMGAAT
****************.:::* **: . * *:.:*:: : **:**..
Mflv_2113|M.gilvum_PYR-GCK SKLNKHFPFVISTMMSNNPVIRPRSIKRKFFEHFPDDLRPGRASRVLAHF
Mvan_4591|M.vanbaalenii_PYR-1 SKLNKHFPFVISTMMSNNPVMRPRWIKRKFFEHFPDDLRPGRASRFLAHF
MSMEG_5202|M.smegmatis_MC2_155 SKLNKHFPFVISTMMSNNPVLRPRFIKRKFFEHFPDDLRPGRPSRWLAHV
TH_0493|M.thermoresistible__bu SKLNRHFPFVISTMMSNNPVFRPRWIKRRFFERFPDDLRPGRASRWLAHL
MAB_4552|M.abscessus_ATCC_1997 SKLNRHFPFVISTMMSNNPLIRARRLKRAFFEKFPDDLRPGRLSRVVAHV
Rv1132|M.tuberculosis_H37Rv SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFKKFPGDLRPGLLSRIVAHV
Mb1163|M.bovis_AF2122/97 SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFKKFPGDLRPGLLSRIVAHV
MMAR_4329|M.marinum_M SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFAKFPDDLRPGLLSRMLAHL
MUL_0139|M.ulcerans_Agy99 SKLNRHFPFVISTMMSNNPLFRPRFIKRMFFAKFPDDLRPGLLSRMLAHL
MAV_1261|M.avium_104 SKLNKHFPFVISTMMSNNPLVRPRWLKRRFFEKFPDDLRPGRLSRWIAHL
****:**************:.*.* :** ** :**.***** ** :**.
Mflv_2113|M.gilvum_PYR-GCK STAIEMLVPLVLFFSHGGWPTAIAAFVMLVFHFGILSAIPMGVPLEWNVF
Mvan_4591|M.vanbaalenii_PYR-1 STAIEGLVPLVLFFSHGGWATAIAAFVMLVFHFGILSAIPMGVPLEWNVF
MSMEG_5202|M.smegmatis_MC2_155 STAIEMLVPLALFFSHGGWPTALAATVMICFHFGILSAIPMGVPLEWNVF
TH_0493|M.thermoresistible__bu ATAIELLVPLVLFFSHGGWATAIAAGVMVLFHFGILSAIPMGVPLEWNVF
MAB_4552|M.abscessus_ATCC_1997 STAVEGLVPFALFFSHGGWVTTVAAGVMVCFHLGILTAIPMGVPLEWNVF
Rv1132|M.tuberculosis_H37Rv STVIEMCVPVVLFVAHGGWPTVVAATIMVCFHLGILTAIPMGVPLEWNVF
Mb1163|M.bovis_AF2122/97 STVIEMCVPVVLFVAHGGWPTVVAATIMVCFHLGILTAIPMGVPLEWNVF
MMAR_4329|M.marinum_M STFIEMFVPVALFLSHGGWPTTAAAIAMVCFHLGILTAIPMGVPLEWNVF
MUL_0139|M.ulcerans_Agy99 STFIEMFVPVALFLSHGGWPTTAAAIAMVCFHLGILTAIPMGVPLEWNVF
MAV_1261|M.avium_104 STAIEMLVPLPLFFCHGGWPVTVAAVVMVCFHLGILVSIPMGVPLEWNVF
:* :* **. **..**** .. ** *: **:*** :************
Mflv_2113|M.gilvum_PYR-GCK MMFSVLALFVGNAGIGLGDLQSPWPIVLFAVVAG-TVVIGNLFPRKVSFL
Mvan_4591|M.vanbaalenii_PYR-1 MMFSVLALFVGNAGIGLADLQSPWPILLFAAVAG-TVVIGNLFPRKVSFL
MSMEG_5202|M.smegmatis_MC2_155 MIFCVATLFVGHADVGITDLSTPLPLLLLAVLVT-TVTLGNLFPRKISFL
TH_0493|M.thermoresistible__bu MIFGVLWLFVTHAQFGLADVGNPWPVAALSLVLAGTVVLGNLFPHKVSFL
MAB_4552|M.abscessus_ATCC_1997 MIFGVLALFVSHANVGLSDMQHPAPVLLLLAVSAGVVATGNLLPRKVSFL
Rv1132|M.tuberculosis_H37Rv MIFGVLSLFVGHACLGLADVKNPVPLAILIAVVAGIVIAGNVFPRKISFL
Mb1163|M.bovis_AF2122/97 MIFGVLSLFVGHACLGLADVKNPVPLAILIAVVAGIVIAGNVFPRKISFL
MMAR_4329|M.marinum_M MIFGVLALFVGHADLGLTDVKSPVPVAILFAVVAGIVILGNLFPRKISFL
MUL_0139|M.ulcerans_Agy99 MIFGVLALFVGHADLGLTDVKSPVPVAILFAVVAGIVILGNLFPRKISFL
MAV_1261|M.avium_104 MIFGVLSLFVAHTGIGLGDLRHPVVVAVLFVVIAGIVVLGNMFPRKISFL
*:* * *** :: .*: *: * : : : * **::*:*:***
Mflv_2113|M.gilvum_PYR-GCK PGMRYYAGNWDTTLWCVKPSASEKITSGIVAIASMPAAQMEKFYGSKETA
Mvan_4591|M.vanbaalenii_PYR-1 PGMRYYAGNWDTTLWCVKPSAAEKIANGIVAIASMPAAQMEKFYGSKETA
MSMEG_5202|M.smegmatis_MC2_155 PGMRYYAGNWDTSLWCVKPSAAEKIEKNIVAIASMPAAQMERYYGSPETA
TH_0493|M.thermoresistible__bu PGMRYYAGNWDTTLWCVKPSAEEKINNGIVAIASMPAAQMERYYGSKETA
MAB_4552|M.abscessus_ATCC_1997 PGMRYYAGNWDTTLWCIKPSASAKIEKGIVAIASMPQAQMERYYGSKDAA
Rv1132|M.tuberculosis_H37Rv AAMRYYAGNWDTTLWCIKPSAEDKINRGIVAIASMPAAQLERFYGK-DRA
Mb1163|M.bovis_AF2122/97 AAMRYYAGNWDTTLWCIKPSAEDKINRGIVAIASMPAAQLERFYGK-DRA
MMAR_4329|M.marinum_M PGMRYYAGNWDTTLWCIKPSADAKIKRGIVAIASMPQAQLERFYGK-DRA
MUL_0139|M.ulcerans_Agy99 PGMRYYAGNWDTTLWCIKPSADAKIKRGIVAIASMPQAQLERFYGK-DRA
MAV_1261|M.avium_104 PGMRYYAGNWDTTLWCIKPSASEKISRGIVAIASMPQAQLERFYGSPEAA
..**********:***:**** ** .******** **:*::**. : *
Mflv_2113|M.gilvum_PYR-GCK EMYQYMGYAFRSFNTHGRAMFTLAHRAMAGQDEGEYVLTDGERICSTAIG
Mvan_4591|M.vanbaalenii_PYR-1 EVYQYMGYAFRSFNTHGRAMFTLAHRAMADGSEDDYVLTDGERICSTAIG
MSMEG_5202|M.smegmatis_MC2_155 QMYLYMGYAFRGFNSHGRALFTLAHRAMAGHDEGEYVLTDGERIVSTAIG
TH_0493|M.thermoresistible__bu EMYLYMGYAFRAFNTHGKALFTLAHRAMAGHDEDDYTIIDGERICSTAIG
MAB_4552|M.abscessus_ATCC_1997 QIYMYIGYAFRAMNTHGRAMFTLAHRAMAGQDESEYVITDGERICSTAIG
Rv1132|M.tuberculosis_H37Rv QIPMYLGYAFRAMNSHGRALFTLAHRAMAGHDEDDYVITDGERVCSTAVG
Mb1163|M.bovis_AF2122/97 QIPMYLGYAFRAMNSHGRALFTLAHRAMAGHDEDDYVITDGERVCSTAVG
MMAR_4329|M.marinum_M QIPMYLGYAFRAMNTHGRALFTLAHRAMAGQDEDDYVITDGERICSTAVG
MUL_0139|M.ulcerans_Agy99 QIPMYLGYAFRAMNTHGRALFTLAHRAMAGQDEDDYVITDGERICSTAVG
MAV_1261|M.avium_104 QIPLYMGYAFRGFNTHGRALFTLAHRAMAGQNEDDYVITDGERICSTAIG
:: *:*****.:*:**:*:*********. .*.:*.: ****: ***:*
Mflv_2113|M.gilvum_PYR-GCK WNFGDGHMHNEQLITALQKRCRFEPGEVRVLILDAQPIHKQRQEYRLVDA
Mvan_4591|M.vanbaalenii_PYR-1 WNFGDGHMHNEQLIAALQKRCQFEPGEVRVLLLDAQPIHRQRQEYRLVDA
MSMEG_5202|M.smegmatis_MC2_155 WNFGDGHMSNEQLVDALQKRCHFEPGEVRIVMLDAQPIQRQTQNYRLVDA
TH_0493|M.thermoresistible__bu WNFGDGHMHNEQLIEAMQQRCGFEPGEVRVVLLDAQPIHRQTQQYRLVDA
MAB_4552|M.abscessus_ATCC_1997 WNFGDGHMHNEQLIAAMQERCHFEPGEVRIVLLDAQPIHRQTQRYRLVDA
Rv1132|M.tuberculosis_H37Rv WNFGDGHLHNEQLIAAMQQRCGFQPGEVRVVLLDAQPIHRQTQEYRLVDA
Mb1163|M.bovis_AF2122/97 WNFGDGHLHNEQLIAAMQQRCGFQPGEVRVVLLDAQPIHRQTQEYRLVDA
MMAR_4329|M.marinum_M WNFGDGHMHNEQLIAAMQQRCNFEPGEVRIVLLDAQPIHKQTQAYRLVDA
MUL_0139|M.ulcerans_Agy99 WNFGDGHMHNEQLIAAMQQRCNFEPGEVRIVLLDAQPIHKQTQAYRLVDA
MAV_1261|M.avium_104 WNFGDGHMHNEQLIAALQERCHFEPGEVRVVLLDAQPIHKQTQAYRLVDA
*******: ****: *:*:** *:*****:::******::* * ******
Mflv_2113|M.gilvum_PYR-GCK ATGEFERGYVMVADMVTRQPWDDTVPVHVTWQKSG-------
Mvan_4591|M.vanbaalenii_PYR-1 ATGEFERGYVMVADMVTRQPWDDTVPVHVTWRR---------
MSMEG_5202|M.smegmatis_MC2_155 ATGEFERGYVKVADMVTRQPWDDDVPVHGVHSLSGERREHA-
TH_0493|M.thermoresistible__bu ATGEFERGYVRVADMVVRQPWDDTVPVHVTSSTLPTDRDSAR
MAB_4552|M.abscessus_ATCC_1997 ATGEFESGYVRVADMVNRQPWDDELPVQVNS-----------
Rv1132|M.tuberculosis_H37Rv ATGEFERGYVRVADMVNRQPWDDDVPVHVLPG----------
Mb1163|M.bovis_AF2122/97 ATGEFERGYVRVADMVNRQPWDDDVPVHVLPG----------
MMAR_4329|M.marinum_M ATGEFERGWVRVSDMVTRQPWADDVPVQVQSE----------
MUL_0139|M.ulcerans_Agy99 ATGEFERGWVRVSDMVTRQPWADDVPVQVQSE----------
MAV_1261|M.avium_104 ATGEFERGIVRVADMVVRQPWDDDVPVQVVSDDAPSVTPE--
****** * * *:*** **** * :**: