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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0484 | guaA | - | 100% (528) | PROBABLE GMP SYNTHASE |
M. thermoresistible (build 8) | TH_0817 | carA | 4e-08 | 26.35% (167) | PROBABLE CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN CARA |
M. thermoresistible (build 8) | TH_0292 | pabA | 4e-07 | 30.25% (119) | POSSIBLE ANTHRANILATE SYNTHASE COMPONENT II TRPG (GLUTAMINE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3429c | guaA | 0.0 | 86.10% (518) | GMP synthase |
M. gilvum PYR-GCK | Mflv_4903 | guaA | 0.0 | 87.81% (517) | bifunctional GMP synthase/glutamine amidotransferase protein |
M. tuberculosis H37Rv | Rv3396c | guaA | 0.0 | 86.10% (518) | GMP synthase |
M. leprae Br4923 | MLBr_00395 | guaA | 0.0 | 83.37% (517) | GMP synthase |
M. abscessus ATCC 19977 | MAB_3718c | - | 0.0 | 82.79% (517) | GMP synthase |
M. marinum M | MMAR_1148 | guaA | 0.0 | 84.53% (517) | GMP synthase, GuaA |
M. avium 104 | MAV_4348 | guaA | 0.0 | 84.47% (515) | bifunctional GMP synthase/glutamine amidotransferase protein |
M. smegmatis MC2 155 | MSMEG_1610 | guaA | 0.0 | 88.39% (517) | bifunctional GMP synthase/glutamine amidotransferase protein |
M. ulcerans Agy99 | MUL_0913 | guaA | 0.0 | 84.33% (517) | GMP synthase |
M. vanbaalenii PYR-1 | Mvan_1516 | guaA | 0.0 | 88.25% (519) | bifunctional GMP synthase/glutamine amidotransferase protein |
CLUSTAL 2.0.9 multiple sequence alignment TH_0484|M.thermoresistible__bu ------VSSSADVNTSRPVLVIDFGAQYAQLIARRIREARVYSEVVPHTA MSMEG_1610|M.smegmatis_MC2_155 ----------MASESPRPVLVIDYGAQYAQLIARRVREARVYSEVVPHTA Mflv_4903|M.gilvum_PYR-GCK ----------MESAHPRPVLIVDFGAQYAQLIARRVREARVFSEVIPHTA Mvan_1516|M.vanbaalenii_PYR-1 ----------MESATPRPVLVVDFGAQYAQLIARRVREARVFSEVIPHTT MLBr_00395|M.leprae_Br4923 --MADSAGLDQPEPSPRPVLVVDFGAQYAQLIARRVREARVFSEVIPHTT MAV_4348|M.avium_104 ------------------MLVVDFGAQYAQLIARRVREARVFSEVIPHTA Mb3429c|M.bovis_AF2122/97 --MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTA Rv3396c|M.tuberculosis_H37Rv --MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTA MMAR_1148|M.marinum_M --MAEPVDLDVAGPVGRPVLVVDFGAQYAQLIARRVREARVFSEVIPHTT MUL_0913|M.ulcerans_Agy99 MPVAEPVDLDVAGPVGRPVLVVDFGAQYAQLIARRVREARVFSEVIPHTT MAB_3718c|M.abscessus_ATCC_199 -------MAQTEQHGDRPVLVIDFGAQYAQLIARRVREARVFSEVIPHSA :*::*:***********:*****:***:**:: TH_0484|M.thermoresistible__bu TVEEIKAKDPQAIVLSGGPASVYAEDAPRLDPGLFDLGVPVFGICYGFQA MSMEG_1610|M.smegmatis_MC2_155 GVEEIKAKDPQAIVLSGGPASVYSEGAPQLDPGLFDLDVPVFGICYGFQA Mflv_4903|M.gilvum_PYR-GCK SIEEIKARDPRAVVLSGGPSSVYADGAPQLDPALFDLDIPVFGICYGFQA Mvan_1516|M.vanbaalenii_PYR-1 SVEEIKARNPRAVVLSGGPASVYADGAPQLDPALFDLDVPVFGICYGFQA MLBr_00395|M.leprae_Br4923 SIEEITARDPLAIVLSGGPASVYTEGAPQLDPALFDLGLPVFGICYGFQA MAV_4348|M.avium_104 TIEEIKARQPRALVLSGGPSSVYEPGAPQLDPAVFDLGVPVFGICYGFQA Mb3429c|M.bovis_AF2122/97 SIEEIRARQPVALVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGFQA Rv3396c|M.tuberculosis_H37Rv SIEEIRARQPVALVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGFQA MMAR_1148|M.marinum_M SIEEIKARDPLALVLSGGPASVYAPGAPQLDPALFDLGLPVFGICYGFQV MUL_0913|M.ulcerans_Agy99 SIEEIKARDPLALVLSGGPASVYAPGAPQLDPALFDLGLPVFGICYGFQV MAB_3718c|M.abscessus_ATCC_199 SVEEIKGRNPRAIVLSGGPSSVYEEGAPQLDPGVFDLDVPVFGICYGFQA :*** .::* *:******:*** .**:***.::**.:**:*******. TH_0484|M.thermoresistible__bu MAQALGGTVTRTGTREYGRTELTVLGGQLHSDLPERQPVWMSHADAVTEA MSMEG_1610|M.smegmatis_MC2_155 MAQALGGTVERTGTSEFGRTELQVTGGDLHSELPATQPVWMSHGDAVTAA Mflv_4903|M.gilvum_PYR-GCK MAQALGGTVARTGTSEYGRTELKVAGGELHSDLPEVQPVWMSHGDAVTEA Mvan_1516|M.vanbaalenii_PYR-1 MAQALGGTVAHTGTSEYGRTELKVAGGQLHTDLPETQPVWMSHGDAVTAA MLBr_00395|M.leprae_Br4923 MAQVLGGTVARTKTSEYGRTELKVLGGDLHSGLPGVQPVWMSHGDAVTAA MAV_4348|M.avium_104 MAQALGGTVAHTGTSEYGRTELKVLGGELHSGLPGVQPVWMSHGDAVTAA Mb3429c|M.bovis_AF2122/97 MAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAA Rv3396c|M.tuberculosis_H37Rv MAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAA MMAR_1148|M.marinum_M MAQALGGTVAHTGTSEYGRTELKVLGGDLHSDLPDIQPVWMSHGDAVTAA MUL_0913|M.ulcerans_Agy99 MAQALGGTVAHTGTSEYGRTELKVLGGDLHSDLPDIQPVWMSHGDAVTAA MAB_3718c|M.abscessus_ATCC_199 MAQVLGGTVAHTGTSEYGRTELTVAGGDLHEGLPDVQPVWMSHGDAVTEA ***.*** * :* * *:***** * **.** ** *******.**** * TH_0484|M.thermoresistible__bu PAGFEVVATSPGSPVAAFEDPARRLAGVQYHPEVIHSPHGQQVLGRFLHE MSMEG_1610|M.smegmatis_MC2_155 PEGFDVVASSAGAPVAGFENRARRLAGVQYHPEVLHSPHGQQVLSRFLHD Mflv_4903|M.gilvum_PYR-GCK PSGFEVVATSVGAPVAAFENRARRLAGVQYHPEVMHSPHGQQVLSRFLHE Mvan_1516|M.vanbaalenii_PYR-1 PEGFEVVATSAGAPVAAFENRARRLAGVQYHPEVMHSPHGQQVLSRFLHE MLBr_00395|M.leprae_Br4923 PDGFDVAASSSGAPVAAFENRDRRLAGVQYHPEVMHTPHGQQVLSRFLHD MAV_4348|M.avium_104 PDGFEVVASSPGAVVAAFENRARRLAGVQYHPEVMHTPHGQQVLSRFLHD Mb3429c|M.bovis_AF2122/97 PDGFDVVASSAGAPVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFLHD Rv3396c|M.tuberculosis_H37Rv PDGFDVVASSAGAPVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFLHD MMAR_1148|M.marinum_M PDGFEVVASSAGAAVAAFENRERRLAGVQYHPEVMHTPHGQQILGRFLHD MUL_0913|M.ulcerans_Agy99 PDGFEVVASSAGAAVAAFENRERRLAGVQYHPEVMHTPHGQQILGRFLHD MAB_3718c|M.abscessus_ATCC_199 PQGFTVVASSEGAPVAAFENRERRLAGVQYHPEVLHSPHGQQVLSRFLHE * ** *.*:* *: **.** ************:*:*****:*.****: TH_0484|M.thermoresistible__bu FAGIGASWTPANIAESLIEQVREQIGDGRAICGLSGGVDSAVAAALVQRA MSMEG_1610|M.smegmatis_MC2_155 FAGIDATWTPANIADQLIEAVREQIGDGRAICGLSGGVDSAVAAALVQRA Mflv_4903|M.gilvum_PYR-GCK FAGIDAAWTPANIAEALVEQVRNQIGDGRAICGLSGGVDSAVAAALVQRA Mvan_1516|M.vanbaalenii_PYR-1 FAGIDATWTPANIAEALVEQVRTQIGDGRAICGLSGGVDSAVAAALVQRA MLBr_00395|M.leprae_Br4923 FAGLDADWTAANIAGVLVEQVRAQIGNGHAICGLSGGVDSAVAAALVQRA MAV_4348|M.avium_104 FAGLGADWTAANIAGVLVEQVRAQIGDGHAICGLSGGVDSAVAAALVQRA Mb3429c|M.bovis_AF2122/97 FAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRA Rv3396c|M.tuberculosis_H37Rv FAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRA MMAR_1148|M.marinum_M FAGIGARWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRA MUL_0913|M.ulcerans_Agy99 FAGIGARWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRV MAB_3718c|M.abscessus_ATCC_199 FAGIESAWTAANIAETLVEQVRTQIGEGRALCALSGGVDSAVAAALVQRA ***: : **.**** *:* ** ***:*:*:*.****************. TH_0484|M.thermoresistible__bu IGDRLTCVFVDHGLLRAGERAQVQRDFVAATGAKLVTVDTSERFLEALSG MSMEG_1610|M.smegmatis_MC2_155 IGDRLTCVFVDHGLLRAGERAQVQRDFVAATGAKLVTVDVADRFLEALTG Mflv_4903|M.gilvum_PYR-GCK IGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDVADRFLEALSG Mvan_1516|M.vanbaalenii_PYR-1 IGDRLTCVFVDHGLLRSGERAQVQRDFVAATGANLVTVDVADRFLEALSG MLBr_00395|M.leprae_Br4923 IGDRLTCIFVDHGLLRDGERGQVQRDFVAATGAKLVTVDAAETFLQALSG MAV_4348|M.avium_104 IGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAADTFLQALAG Mb3429c|M.bovis_AF2122/97 IGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSG Rv3396c|M.tuberculosis_H37Rv IGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSG MMAR_1148|M.marinum_M IGDRLTCVFVDHGLLRAGERAQVERDFVAATKANLVTVDVADTFLAALSG MUL_0913|M.ulcerans_Agy99 IGDRLTCVFVDHGLLRAGERAQVERDFVAATKANLVTVDVADTFLAALSG MAB_3718c|M.abscessus_ATCC_199 IGDRLTCVFVDHGLLRSGERAQVEHDFVAATGATLVTVDASETFLGELAG *******:******** ***.**::****** *.*****.:: ** *:* TH_0484|M.thermoresistible__bu VTNPEGKRKIIGREFIRAFEGAVREALGENAAANDDEVEFLVQGTLYPDV MSMEG_1610|M.smegmatis_MC2_155 VTNPEGKRKIIGREFIRAFEGAVRDLVEDEGSG---DIDFLVQGTLYPDV Mflv_4903|M.gilvum_PYR-GCK VTNPEGKRKIIGREFIRAFEGAVRDTVERSDGS-DVPVEFLVQGTLYPDV Mvan_1516|M.vanbaalenii_PYR-1 VTNPEGKRKIIGREFIRAFEGAVRDALESQDGS-DVPVEFLVQGTLYPDV MLBr_00395|M.leprae_Br4923 VTNPEGKRKIIGRQFIRAFEGAVRDLLGDSTFD--SGIEFLVQGTLYPDV MAV_4348|M.avium_104 VTNPEGKRKIIGRQFIRAFEGAVRDVLGD------KPVEFLVQGTLYPDV Mb3429c|M.bovis_AF2122/97 VSAPEGKRKIIGRQFIRAFEGAVRDVLDG------KTAEFLVQGTLYPDV Rv3396c|M.tuberculosis_H37Rv VSAPEGKRKIIGRQFIRAFEGAVRDVLDG------KTAEFLVQGTLYPDV MMAR_1148|M.marinum_M VTDPEGKRKIIGRQFIRAFEGAVRDVLDG------RDIEFLVQGTLYPDV MUL_0913|M.ulcerans_Agy99 VTDPEGKRKIIGRQFIRAFEGAVRDVLDG------RDVEFLVQGTLYPDV MAB_3718c|M.abscessus_ATCC_199 VTDPEAKRKIIGREFIRSFEGAVSDVVGDSRRDDTAGIQFLVQGTLYPDV *: **.*******:***:***** : : :*********** TH_0484|M.thermoresistible__bu VESGGGAGTANIKSHHNVGGLPDDLKFKLVEPLRLLFKDEVRAVGRELGL MSMEG_1610|M.smegmatis_MC2_155 VESGGGSGTANIKSHHNVGGLPDDLKFKLVEPLRLLFKDEVRAVGRELGL Mflv_4903|M.gilvum_PYR-GCK VESGGGSGTANIKSHHNVGGLPDDLKFALVEPLRLLFKDEVRAVGRELGL Mvan_1516|M.vanbaalenii_PYR-1 VESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGL MLBr_00395|M.leprae_Br4923 VESGGGSGTANIKSHHNVGGLPDNLRFKLVEPLRLLFKDEVRAVGRQLDL MAV_4348|M.avium_104 VESGRGSGTANIKSHHNVGGLPGDLKFTLVEPLRLLFKDEVRAVGRELGL Mb3429c|M.bovis_AF2122/97 VESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGL Rv3396c|M.tuberculosis_H37Rv VESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGL MMAR_1148|M.marinum_M VESGGGSGTANIKSHHNVGGLPDDLKFALVEPLRLLFKDEVRAVGRELGL MUL_0913|M.ulcerans_Agy99 VESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGL MAB_3718c|M.abscessus_ATCC_199 VESGGGSGTANIKSHHNVGGLPEDLTFTLVEPLRLLFKDEVRAVGRELGL **** *:*************** :* * ******************:*.* TH_0484|M.thermoresistible__bu PEEIVARQPFPGPGLAIRIVGEVTAERLETLRRADAIVREELTAAGLDHQ MSMEG_1610|M.smegmatis_MC2_155 PEEIVARQPFPGPGLGIRIVGEVTAERLETLRRADAIAREELTAAGLDNQ Mflv_4903|M.gilvum_PYR-GCK PEEIVARQPFPGPGLGIRIIGEVTSDRLDTLRRADVIAREELTAAGLDHQ Mvan_1516|M.vanbaalenii_PYR-1 PEEIVARQPFPGPGLGIRIVGEVTAERLDTLRRADAIAREELTSAGLDHQ MLBr_00395|M.leprae_Br4923 PEEIVARQPFPGPGLGIRIVGEVTAERLDTLRRADSIAREELTTAGLDYQ MAV_4348|M.avium_104 PEEIVARQPFPGPGLGIRIVGEVTATRLDTLRRADSIAREELTAAGLDSL Mb3429c|M.bovis_AF2122/97 PEEIVARQPFPGPGLGIRIVGEVTAKRLDTLRHADSIVREELTAAGLDNQ Rv3396c|M.tuberculosis_H37Rv PEEIVARQPFPGPGLGIRIVGEVTAKRLDTLRHADSIVREELTAAGLDNQ MMAR_1148|M.marinum_M PEEIVARQPFPGPGLGIRIVGEVTGQRLDTLRRADSIAREELTAAGLDNQ MUL_0913|M.ulcerans_Agy99 PEEIVARQPFPGPGLGIRIVGEVTGQRLDTLRRADSIARKELTAAGLDNQ MAB_3718c|M.abscessus_ATCC_199 PEEIVGRQPFPGPGLAIRIVGEVTPDRLDTLRRADAIAREELTAAGQDRN *****.*********.***:**** **:***:** *.*:***:** * TH_0484|M.thermoresistible__bu IWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYDV MSMEG_1610|M.smegmatis_MC2_155 IWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEV Mflv_4903|M.gilvum_PYR-GCK IWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEV Mvan_1516|M.vanbaalenii_PYR-1 IWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEV MLBr_00395|M.leprae_Br4923 IWQCPVVLLADVRSVGVQGDNRSYGHPIVLRPVSSEDAMTADWTWVPYEV MAV_4348|M.avium_104 IWQCPVVLLGEVRSVGVQGDNRTYGHPIVLRPVTSEDAMTADWTRVPYEV Mb3429c|M.bovis_AF2122/97 IWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEV Rv3396c|M.tuberculosis_H37Rv IWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEV MMAR_1148|M.marinum_M IWQCPVVLLADVRSVGVQGDNRTYGHPIVLRPVSSEDAMTADWTRVPFEV MUL_0913|M.ulcerans_Agy99 IWQCPVVLLADVRSVGVQGDNRTYGHPIVLRPVSSEDAMTADWTRVPFEV MAB_3718c|M.abscessus_ATCC_199 IWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRLPYEV *********.:*********.*:**********:********** :*::* TH_0484|M.thermoresistible__bu LERISTRITNEVAEVNRVVLDITSKPPATIEWE MSMEG_1610|M.smegmatis_MC2_155 LERISTRITNEVREVNRVVLDITSKPPGTIEWE Mflv_4903|M.gilvum_PYR-GCK LERISTRITNEVPEVNRVVLDITSKPPGTIEWE Mvan_1516|M.vanbaalenii_PYR-1 LERISTRITNEVREVNRVVLDVTSKPPGTIEWE MLBr_00395|M.leprae_Br4923 LECISTRITNEVAEVNRVVLDITNKPPGTIEWE MAV_4348|M.avium_104 LERISTRITNEVPEVNRVVLDITSKPPGTIEWE Mb3429c|M.bovis_AF2122/97 LERISTRITNEVAEVNRVVLDITSKPPATIEWE Rv3396c|M.tuberculosis_H37Rv LERISTRITNEVAEVNRVVLDITSKPPATIEWE MMAR_1148|M.marinum_M LERISTRITNEVPEVNRVVLDVTSKPPGTIEWE MUL_0913|M.ulcerans_Agy99 LERISTRITNEVPEVNRVVLDVTSKPPGTIEWE MAB_3718c|M.abscessus_ATCC_199 LERISTRITNEVPEVNRVVLDITSKPPGTIEWE ** ********* ********:*.***.*****