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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0438 | cobG | - | 100% (379) | Possible cobalamin biosynthesis protein CobG |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2090 | cobG | 1e-128 | 63.03% (376) | cobalamin biosynthesis protein CobG |
M. gilvum PYR-GCK | Mflv_3106 | - | 1e-130 | 63.85% (379) | precorrin-3B synthase |
M. tuberculosis H37Rv | Rv2064 | cobG | 1e-128 | 63.03% (376) | cobalamin biosynthesis protein CobG |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2200c | - | 1e-109 | 56.12% (392) | cobalamin biosynthesis protein CobG |
M. marinum M | MMAR_3044 | - | 1e-129 | 64.27% (375) | cobalamin biosynthesis protein |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_3871 | cobG | 1e-132 | 63.93% (377) | precorrin-3B synthase |
M. ulcerans Agy99 | MUL_2288 | - | 1e-129 | 64.27% (375) | cobalamin biosynthesis protein |
M. vanbaalenii PYR-1 | Mvan_3429 | - | 1e-130 | 63.40% (377) | precorrin-3B synthase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3106|M.gilvum_PYR-GCK MVRAREKDACPGALQTHRAADGDLSRIRLPGGAITPPQLEVVAQAAIDLA Mvan_3429|M.vanbaalenii_PYR-1 MARARDDDACPGALQTHRAADGDLARIRLPGGAITARQLEAVAQAAVNFG MSMEG_3871|M.smegmatis_MC2_155 MTRTRDQDACPGALTVHQAADGALVRIRLAGGAITAAQLATLADVANDLG Mb2090|M.bovis_AF2122/97 MAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFG Rv2064|M.tuberculosis_H37Rv MAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFG MMAR_3044|M.marinum_M MTRARDADACPGALQVHQAADGALVRVRLPGGRLTADQLAALARASNELA MUL_2288|M.ulcerans_Agy99 MTRARDADACPGALQVHQAADGALVRVRLPGGRLTADQLAALARASNELA TH_0438|M.thermoresistible__bu VERAREHDACPGALSVHPAADGALARIRLPGGMLTPAQLTALADAARRFG MAB_2200c|M.abscessus_ATCC_199 MTRSSADDACPGALRLHEAADGALARIRLPGGMLSSAQLAALAEAAGDHG : : ******* * **** * *:**.** ::. ** .:* .: . Mflv_3106|M.gilvum_PYR-GCK ASTLELTSRGNLQIRGVRDTAAVADLLAGAGLLPSATHERVRNIVASPLS Mvan_3429|M.vanbaalenii_PYR-1 TATLELTSRANLQIRGIHDTGAVAALLTDAGLLPSATHERVRNIVASPLS MSMEG_3871|M.smegmatis_MC2_155 SPAMELTSRGNIQIRGLTDTDAAAAALAGAGLLPSPTHERVRNIVASPLT Mb2090|M.bovis_AF2122/97 SATLELTARGNVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLS Rv2064|M.tuberculosis_H37Rv SATLELTARGNVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLS MMAR_3044|M.marinum_M SATLELTARGNLQLRAITDVMAVADAIANAGLLPSPTHERVRNIVASPLS MUL_2288|M.ulcerans_Agy99 SATLELTARGNLQLRAITDVMAVADAIANAGLLPSPTHERVRNIVASPLS TH_0438|M.thermoresistible__bu SEAMELTSRGNIQIRGISDPAAVADAVAAAGLLPSPTHETVRNIVASPLS MAB_2200c|M.abscessus_ATCC_199 APILELTSRGNVQLRSVRDANAVGALLSEAGLLPSPRHERVRNIVASPLS : :***:*.*:*:*.: * *.. :: ******. ** *********: Mflv_3106|M.gilvum_PYR-GCK GRHGGLCDVRALVADLDAAVQRDPVLAELPGRFLFGFDDGRGDISGLGAD Mvan_3429|M.vanbaalenii_PYR-1 GRSGGFCDARDLVRSLDHAVQQDPRLARLPGRFLFGIDDGRGDISGLGAD MSMEG_3871|M.smegmatis_MC2_155 GRSGGVADVGALVSELDAAIQAEPELAGLPGRFLFGLDDGRGDISGLGPD Mb2090|M.bovis_AF2122/97 GRAGGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGAD Rv2064|M.tuberculosis_H37Rv GRAGGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGAD MMAR_3044|M.marinum_M GRVGGLADVQSWVGELDAAICAEPLLAQLGGRFWFSIDDGRADVSGLGAD MUL_2288|M.ulcerans_Agy99 GRVGGLADLQSWVGELDAAICAEPLLAQLGGRFWFSIDDGRADVSGLGAD TH_0438|M.thermoresistible__bu GRCGGATDIRPWVTRLDHAIQSELALAALPGRFLFGIDDGRGDIAALAAD MAB_2200c|M.abscessus_ATCC_199 GRAGEFPDARPLVSALDRGLTAAATLAELPGRFLFSLDDGRGDMAAMGAD ** * * * ** .: ** * *** *.:****.*::.:..* Mflv_3106|M.gilvum_PYR-GCK AGVHALDDSTA--ALLLAGRDTGVRVALS-SAVDELLAVARRFVDGRGKH Mvan_3429|M.vanbaalenii_PYR-1 AGIHVLDGHTA--ALLLAGRDTGVRLPLG-HVVDELLSVAARFLQVRGTA MSMEG_3871|M.smegmatis_MC2_155 AGVHMLDAGTG--ALLLGGCDTGVRIDRA-GVVPTLITVARRFAKVHGKA Mb2090|M.bovis_AF2122/97 VGVQVFPDGP---RLLLTGRDTGVRVA---DVAETLIEVALRFVKIRETA Rv2064|M.tuberculosis_H37Rv VGVQVFPDGP---RLLLTGRDTGVRVA---DVAETLIEVALRFVKIRETA MMAR_3044|M.marinum_M VGVHVLADGC---AVLLDGRDTGVRLAPD-DVVPTLTELAVRFTQIRGNC MUL_2288|M.ulcerans_Agy99 VGVHVLADGC---AVLLDGRDTGVRLAPD-DVVPTLTELAVRFTQMRGNF TH_0438|M.thermoresistible__bu VAVQTLGASGDEAAVLLAGRDSGVRVAAG-DAVEVMVTVARRFTASRGGA MAB_2200c|M.abscessus_ATCC_199 IGLRHDQKGWR---LLLGGRTTSVCDGDAVDAVERMLTAARKFVEIRGNA .:: :** * :.* .. : * :* : Mflv_3106|M.gilvum_PYR-GCK WRVGELDDPA-ILLDGRAPTERPGGT-WQARTRPPVGWIEQTDGR----- Mvan_3429|M.vanbaalenii_PYR-1 WRVDELDDPT-TLLGDRTPTAEPGAT-WPAHSRPPVGWIEQDDGR----- MSMEG_3871|M.smegmatis_MC2_155 WRVGELDDLA-PLLEGLTATGAGGQR-WAPTVRPPVGWIPQRDGR----- Mb2090|M.bovis_AF2122/97 WRVTELADIG-ELQSG----VELGPS-VRPVTKTPVGWIPQDDSR----- Rv2064|M.tuberculosis_H37Rv WRVTELADIG-ELQSG----VELGPS-VRPVTKTPVGWIPQDDSR----- MMAR_3044|M.marinum_M WRVNELIDPS-VLVPG----AAPGSR-FPAVTKAPVGWIPQRDGR----- MUL_2288|M.ulcerans_Agy99 WRVNELIDPS-VLVPG----AAPGSR-FPAVTKAPVGWIPQRDGR----- TH_0438|M.thermoresistible__bu WRIAELDDTS-ALLDGFARRAAPAPA-TPAP-RPPIGWIPQDDGR----- MAB_2200c|M.abscessus_ATCC_199 WRVAELPEGAGTLARAIDAVFIDGPPDPTPAPRAPVGWIEQLRTGESPGE **: ** : * . . :.*:*** * Mflv_3106|M.gilvum_PYR-GCK -IALGAAVPLGVLDAQVARYLAAVEAPLTVTPWRSVLIFDLDEGVADVAL Mvan_3429|M.vanbaalenii_PYR-1 -IALGAAVPLGVLDAQVARYLAAVEAPLAVTPWRSVLLFDLDEGVADVAL MSMEG_3871|M.smegmatis_MC2_155 -VALGAGVPLGVLSARDAQFLAAIEAPIVITPWRSVLVFDLDEGVADTAL Mb2090|M.bovis_AF2122/97 -VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAAL Rv2064|M.tuberculosis_H37Rv -VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAAL MMAR_3044|M.marinum_M -VTLGAAVPLGILPARVAEFLAAIEAPIAITPWRSVLVFDLDEAIADTAL MUL_2288|M.ulcerans_Agy99 -VTLGAAVPLGILPARVAEFLAAIEAPIAITPWRSVLVFDLDEAIADTAL TH_0438|M.thermoresistible__bu -VTLAAGVPLGVLTARLAEFLAAIDAPLIVTPWRSVLVCDLDEGVADTAV MAB_2200c|M.abscessus_ATCC_199 LVTLGAAVPLGQLPARVAALLAAVEKPVIVTPWRSVLLCDLPHGDADAVL ::*.*.**** * *: * ***:: *: :*******: ** .. **..: Mflv_3106|M.gilvum_PYR-GCK RVLAPLGLIFDEDSAWLSVSACTGSPGCAHSAADVRADAGAAVDPSIAV- Mvan_3429|M.vanbaalenii_PYR-1 RVLAPLGLVFDENSPWLSVSACTGSPGCERSVADVRADAAAAVDDPVTV- MSMEG_3871|M.smegmatis_MC2_155 RVLAPMGLVFDENSPWLDVSACTGSPGCAKSLTDVRADAAAAAQEPSAN- Mb2090|M.bovis_AF2122/97 RVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAG- Rv2064|M.tuberculosis_H37Rv RVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAG- MMAR_3044|M.marinum_M RVLAPLGLVFDENSPWLNVSACTGSPGCASSAADVRADAALSVRTEAAAS MUL_2288|M.ulcerans_Agy99 RVLAPLGLVFDENSPWLNVSACTGSPGCASSAADVRADAALSVRTEAAAS TH_0438|M.thermoresistible__bu RVLAPLGLIFDENSPWLRISSCTGLPGCARSAADVRADAARAATEAAPXG MAB_2200c|M.abscessus_ATCC_199 RVLAPLGLVFDERSPWLNASSCTGLPGCGRSRTDVHADVRLEVAEEIASG *****:**:*** *.** *:*** *** * :**:**. . Mflv_3106|M.gilvum_PYR-GCK -----HRHFVGCDRACGSPADAQVLVATGDGYRSREAHP Mvan_3429|M.vanbaalenii_PYR-1 -----HRHFVGCERACGSPADGEVLVATGDGYRARKRHP MSMEG_3871|M.smegmatis_MC2_155 -----HRHFVGCERACGSPPVGDVLVATEDGYRLRIASP Mb2090|M.bovis_AF2122/97 -----HRHFVGCERACGSPPAGEVLVATGGGYRRLRP-- Rv2064|M.tuberculosis_H37Rv -----HRHFVGCERACGSPPAGEVLVATGGGYRRLRP-- MMAR_3044|M.marinum_M GV---HRHFVGCERACGSPLAGEVLVATAQGYRLLRKA- MUL_2288|M.ulcerans_Agy99 GV---HRHFVGCERACGSPLAGEVLVATAQGYRLLRKA- TH_0438|M.thermoresistible__bu QTR-VHRHFVGCERACGTPPGAQVLVATGEGYRLRNPHP MAB_2200c|M.abscessus_ATCC_199 IHSPVHRHWVGCPRACGSPSTGQVLVATELGYRPLERHP ***:*** ****:* .:***** ***