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M. thermoresistible (build 8) TH_0273 (cdsA)

annotation: PROBABLE INTEGRAL MEMBRANE PHOSPHATIDATE CYTIDYLYLTRANSFERASE CDSA (CDP-DIGLYCERIDE SYNTHETASE) (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE) (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE)
coordinates: 612936 - 613823
length: 296

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0273 cdsA - 100% (296) PROBABLE INTEGRAL MEMBRANE PHOSPHATIDATE CYTIDYLYLTRANSFERASE CDSA (CDP-DIGLYCERIDE SYNTHETASE) (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE) (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2905c cdsA 1e-108 64.16% (293) integral membrane phosphatidate cytidylyltransferase CdsA
M. gilvum PYR-GCK Mflv_4122 - 1e-122 73.22% (295) phosphatidate cytidylyltransferase
M. tuberculosis H37Rv Rv2881c cdsA 1e-108 64.16% (293) integral membrane phosphatidate cytidylyltransferase CdsA
M. leprae Br4923 MLBr_01589 - 1e-103 62.98% (289) putative phosphatidate cytidylyltransferase
M. abscessus ATCC 19977 MAB_3186c - 1e-101 60.96% (292) phosphatidate cytidylyltransferase (CdsA)
M. marinum M MMAR_1828 cdsA 1e-101 59.73% (298) integral membrane phosphatidate cytidylyltransferase CdsA
M. avium 104 MAV_3731 cdsA 1e-102 63.54% (288) phosphatidate cytidylyltransferase
M. smegmatis MC2 155 MSMEG_2543 cdsA 1e-114 68.47% (295) phosphatidate cytidylyltransferase
M. ulcerans Agy99 MUL_2076 cdsA 1e-100 59.73% (298) integral membrane phosphatidate cytidylyltransferase CdsA
M. vanbaalenii PYR-1 Mvan_2222 - 1e-116 70.59% (289) phosphatidate cytidylyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0273|M.thermoresistible__bu      -------------VPAD---------ET-QKVGRAGRNLPAAIAVGVLLG
Mflv_4122|M.gilvum_PYR-GCK          --MTDQHSTPVGPQPVD---------EPPKKSSRAGRNLPAAIAVGVLLG
MSMEG_2543|M.smegmatis_MC2_155      --MTDQQASLVASKPVG---------EPQKKQSRAGRNLPAAIGVGVGLG
Mvan_2222|M.vanbaalenii_PYR-1       --MTDQHSTPVISKPVN---------EPPKKASRAGRNLPAAIAVGVALG
MAB_3186c|M.abscessus_ATCC_199      --MGDTDAAPAPGSSPA---------PPAGAKSRAGRNLPAAIGVGVALA
Mb2905c|M.bovis_AF2122/97           MTTNDAGTGNPAEQPARGAKQ-----QPATETSRAGRDLRAAIVVGLSIG
Rv2881c|M.tuberculosis_H37Rv        MTTNDAGTGNPAEQPARGAKQ-----QPATETSRAGRDLRAAIVVGLSIG
MMAR_1828|M.marinum_M               MANTDATTGTPADEPVQ---------EPPKKASRAGRDLPAAIAVGLSIG
MUL_2076|M.ulcerans_Agy99           MANTDATTGTPADEPVQ---------EPPKKASRAGRDLPAAIAVGLSIG
MLBr_01589|M.leprae_Br4923          MASTDPGTGTPLDESVPGIKR--AMRQSTKNTPRAGRNLPAAIAVGLSIG
MAV_3731|M.avium_104                MATSDPGAGDEPEHAVENTTEGAAGQRAKKKTSRAGRDLRAAIAVGAGIG
                                                  .            .     ****:* *** **  :.

TH_0273|M.thermoresistible__bu      GGLIAVLVWAPYVWLGVLAVAIAIATREVTARLREAGYQIPLVPLLLGGQ
Mflv_4122|M.gilvum_PYR-GCK          GGLIAILIFAPYLWLALLSAAVAMATYEVSSRLGEAGYRIPFVPLLVGGQ
MSMEG_2543|M.smegmatis_MC2_155      GGVIAILLFAPLVWVGVVAAAMAVATHEVVRRLRTGGFSIPVVPLLIGGQ
Mvan_2222|M.vanbaalenii_PYR-1       AMLIVVLLFAPKVWVGVVSVAIAIATHEVVRRLREGGYSIPVVPLLVGGQ
MAB_3186c|M.abscessus_ATCC_199      ALIIFSLLYQKEIWVGIISVFLGIAMWEVTKRLRQADISVPFIPLFFGGQ
Mb2905c|M.bovis_AF2122/97           LVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLREAGYLIPVIPLLIGGQ
Rv2881c|M.tuberculosis_H37Rv        LVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLREAGYLIPVIPLLIGGQ
MMAR_1828|M.marinum_M               LFLVATLVFAPRGWVAICAFAMVVATHEVVRRLREAGYLIPVVPLLIGGQ
MUL_2076|M.ulcerans_Agy99           LFLVATLVFAPRGWVAICAFAMVVATHEVVRRLREAGYLIPVVPLLIGGQ
MLBr_01589|M.leprae_Br4923          GVLVATLVFAPRIWVVLCAGAIFVASHEVVRRLREAGYVIPAIPLLIGGQ
MAV_3731|M.avium_104                AVLIVTLVFAPRFWVPIVAMAILVASHEVVRRLREAGYVIPVIPLLAGGQ
                                      ::  *::    *: : :    :*  **  **  ..  :* :**: ***

TH_0273|M.thermoresistible__bu      ATLWLTWPFGAAGALGGFAGMVVTCMIWRLIAQGRAAAPVRTSADPDLSG
Mflv_4122|M.gilvum_PYR-GCK          ATLWLTWPFGPSGALGGFAATVVVCMIWRLVGHG-------------LN-
MSMEG_2543|M.smegmatis_MC2_155      AMVWLTLPFGPAGALGGFGATVVLCLIWRLLSGG-------------LT-
Mvan_2222|M.vanbaalenii_PYR-1       AMIWLTWPFGAAGALGAFGGTVVVCMIWRLVSGG-------------LS-
MAB_3186c|M.abscessus_ATCC_199      AMIWLTWPWGTAGSVGAFAATVVVCMIWRLLSQG-------------LG-
Mb2905c|M.bovis_AF2122/97           AAVWLTWPFGAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTG-------G
Rv2881c|M.tuberculosis_H37Rv        AAVWLTWPFGAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTG-------G
MMAR_1828|M.marinum_M               LTVWLSWPYGVRGVLAGFGAMIVVCMFWRLFMQDNRPHDGAGS-----DG
MUL_2076|M.ulcerans_Agy99           LTVWLSWPYGVRGVLAGFGAMIVVCMFWRLFMQDNLPHDGAGS-----DG
MLBr_01589|M.leprae_Br4923          FTVWLTWPYRTVGALAGFGATVVVCMIWRLVMHDNSKQHESREA----LA
MAV_3731|M.avium_104                LTVWLTWPFHAAGALAGFGVTVVACLFWRLFMQDNRKRPEP-------FA
                                      :**: *:   * :..*.  :* *::***.  .                

TH_0273|M.thermoresistible__bu      QPGPTNYLRDIAATIFLATWVPLFAGFGALLIYPDDGPARVFSFMLAVVC
Mflv_4122|M.gilvum_PYR-GCK          -HAPQNYTRDIGATVFLATWVPLFASFGALLIYPDDGANRVFCLMLGVVF
MSMEG_2543|M.smegmatis_MC2_155      -AAPVNYLRDVSVTVFLAAWIPLFGAFGALLIYPDDGAGRVFCLMLGVVA
Mvan_2222|M.vanbaalenii_PYR-1       -DAPQNYLRDMSTTVFLATWVPLFASFGVLLIYPDDGAGRVFCLMLGVVA
MAB_3186c|M.abscessus_ATCC_199      -SQPVNYLRDVAITVFVAAWIPLFASFGALLVYPDNGAEQVFCLMLGVTF
Mb2905c|M.bovis_AF2122/97           APSPGNYLSDVSATVFLAVWVPLFCSFGAMLVYPENGSGWVFCMMIAVIA
Rv2881c|M.tuberculosis_H37Rv        APSPGNYLSDVSATVFLAVWVPLFCSFGAMLVYPENGSGWVFCMMIAVIA
MMAR_1828|M.marinum_M               VPASGTYLRDTSATVFLAVWVVLFGSFAAMLVYPPNGTGWVFCVMIAIIA
MUL_2076|M.ulcerans_Agy99           VPASGTYLRDTSTTVFLAVWVVLFGSFAAMLVYPPNGTGWVFCVMIAIIA
MLBr_01589|M.leprae_Br4923          GPPVSNYLRDASATVFLAAWVPLFASFAALLVYPKDGAGRVFCLMIAVVA
MAV_3731|M.avium_104                GSPSANYLRDASATVFLACWVPLFASFAALLVYPADGAGRVFCLMITVVA
                                         .*  * . *:*:* *: ** .*..:*:** :*.  **..*: :  

TH_0273|M.thermoresistible__bu      SDIGGYTAGVLFGRHPMVPAISPKKSWEGFAGSMVFGTTAAVLAVVFLMD
Mflv_4122|M.gilvum_PYR-GCK          SDIGGYVAGVLFGRHTMAPAISPKKSWEGLAGSLLFGVTASVLAVVFLLD
MSMEG_2543|M.smegmatis_MC2_155      SDVGGYTAGVLFGKHPMVPAISPKKSWEGLAGSLVLGIVVSVLAVTFLLD
Mvan_2222|M.vanbaalenii_PYR-1       SDVGGYTAGVLFGKHPMAPAISPKKSWEGLAGSLVLGVVVSSLAVQFLTD
MAB_3186c|M.abscessus_ATCC_199      SDIGGYAAGVLFGKHPMAPAISPKKSWEGLAGSLVVGTTASTLAVTFLLG
Mb2905c|M.bovis_AF2122/97           SDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVG
Rv2881c|M.tuberculosis_H37Rv        SDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVG
MMAR_1828|M.marinum_M               SDVGGYTVGVLFGKHPMVPAISPKKSWEGFVGSLFCGIVATTITATFLAH
MUL_2076|M.ulcerans_Agy99           SDVGGYTVGVLFGKHPMVPTISPKKSWEGFAGSLFCGIVATTITATFLAH
MLBr_01589|M.leprae_Br4923          SDVGGYTVGVLFGKHPLVPRISPNKSWEGFAGSLVCGTTATILTATFLAG
MAV_3731|M.avium_104                SDVGGYAVGVLFGKHPMVPAISPKKSWEGLAGSLVLGITAATLAATFLAG
                                    **:***..*****:*.:.* ***:*****:.**:. * ..: ::. **  

TH_0273|M.thermoresistible__bu      KPWWAGAALGVLLVITATLGDLVESQFKRDLGIKDMGSLLPGHGGLMDRI
Mflv_4122|M.gilvum_PYR-GCK          KPWWAGVALGLMLVITGTLGDLVESQFKRDLGIKDMSNLLPGHGGMMDRI
MSMEG_2543|M.smegmatis_MC2_155      KPAWVGVPLGIMLVITGTLGDLVESQVKRDLGIKDMGTLLPGHGGLMDRI
Mvan_2222|M.vanbaalenii_PYR-1       NPWWIGIPLGLMLVITGTLGDLVESQVKRDLGIKDMGTLLPGHGGLMDRL
MAB_3186c|M.abscessus_ATCC_199      HHPFVGIALGVMLVITGTLGDLVESQVKRDLGIKDMGTLLPGHGGIMDRL
Mb2905c|M.bovis_AF2122/97           KTPWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRL
Rv2881c|M.tuberculosis_H37Rv        KTPWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRL
MMAR_1828|M.marinum_M               EPPWVGALLGVLFVLTTTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRL
MUL_2076|M.ulcerans_Agy99           EPPWVGALLGVLFVLTTTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRL
MLBr_01589|M.leprae_Br4923          KTPWVGALLSFVLVLTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRL
MAV_3731|M.avium_104                KAPWVGALLGVVLVFTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRL
                                    .  : *  *..::*:* :********.*********. *******:***:

TH_0273|M.thermoresistible__bu      DGMLPSAVATWIVLSLLA
Mflv_4122|M.gilvum_PYR-GCK          DAALPSAVATWIVLTLLA
MSMEG_2543|M.smegmatis_MC2_155      DSVLPSAVATWIVLTLLA
Mvan_2222|M.vanbaalenii_PYR-1       DSILPSAVATWIVLSLLA
MAB_3186c|M.abscessus_ATCC_199      DSLLPSAVATWIVLTLFI
Mb2905c|M.bovis_AF2122/97           DGILPSAVAAWIVLTLLP
Rv2881c|M.tuberculosis_H37Rv        DGILPSAVAAWIVLTLLP
MMAR_1828|M.marinum_M               DGVLPSAVAAWIVMSLLT
MUL_2076|M.ulcerans_Agy99           DGVLPSAVAAWIVMSLLT
MLBr_01589|M.leprae_Br4923          DGVLPSAVVAWTMLTLLP
MAV_3731|M.avium_104                DGVLPSAVAAWTVLTLVP
                                    *. *****.:* :::*.

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0273	cdsA	-	100% (296)	PROBABLE INTEGRAL MEMBRANE PHOSPHATIDATE CYTIDYLYLTRANSFERASE CDSA (CDP-DIGLYCERIDE SYNTHETASE) (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE) (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE)