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M. thermoresistible (build 8) TH_0271 (pyrH)

annotation: PROBABLE URIDYLATE KINASE PYRH (UK) (URIDINE MONOPHOSPHATE KINASE) (UMP KINASE)
coordinates: 611631 - 612296
length: 222

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0271pyrH-100% (222)PROBABLE URIDYLATE KINASE PYRH (UK) (URIDINE MONOPHOSPHATE KINASE) (UMP KINASE)
M. thermoresistible (build 8)TH_2282ask7e-0825.91% (247) ASPARTOKINASE ASK (ASPARTATE KINASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2907cpyrH1e-10987.33% (221) uridylate kinase
M. gilvum PYR-GCKMflv_4124pyrH1e-11291.40% (221) uridylate kinase
M. tuberculosis H37RvRv2883cpyrH1e-10987.33% (221) uridylate kinase
M. leprae Br4923MLBr_01591pyrH1e-11089.14% (221) uridylate kinase
M. abscessus ATCC 19977MAB_3188c-1e-10988.64% (220) uridylate kinase PyrH
M. marinum MMMAR_1826pyrH1e-10989.14% (221) uridylate kinase PyrH
M. avium 104MAV_3733pyrH1e-10990.05% (221) uridylate kinase
M. smegmatis MC2 155MSMEG_2540pyrH1e-11493.21% (221) uridylate kinase
M. ulcerans Agy99MUL_2074pyrH1e-10989.14% (221) uridylate kinase PyrH
M. vanbaalenii PYR-1Mvan_2220pyrH1e-11190.50% (221) uridylate kinase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0271|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2540|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2220|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3188c|M.abscessus_ATCC_199      --------------------------------------------------
Mb2907c|M.bovis_AF2122/97           --------------------------------------------------
Rv2883c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1826|M.marinum_M               --------------------------------------------------
MUL_2074|M.ulcerans_Agy99           MSGPGPPFQQACLVPSGAPRLGSTARARWRIPGAPAVQTSLRRCPRPDTG
MLBr_01591|M.leprae_Br4923          --------------------------------------------------
MAV_3733|M.avium_104                --------------------------------------------------
                                                                                      

TH_0271|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2540|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2220|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3188c|M.abscessus_ATCC_199      --------------------------------------------------
Mb2907c|M.bovis_AF2122/97           -----------------------------------------MTEP---DV
Rv2883c|M.tuberculosis_H37Rv        -----------------------------------------MTEP---DV
MMAR_1826|M.marinum_M               -----------------------------------------MTES---DV
MUL_2074|M.ulcerans_Agy99           HAFGAVGYERTPRLPRSSAMRQDMRGRSGWLPGWHSHARRFMTES---DV
MLBr_01591|M.leprae_Br4923          -----------------------------------------MTESWESQV
MAV_3733|M.avium_104                --------------------------------------------------
                                                                                      

TH_0271|M.thermoresistible__bu      -------------------------------------------------M
MSMEG_2540|M.smegmatis_MC2_155      --MADSN---VAGRAAPIRP-----------------LYTRVLLKLGGEM
Mflv_4124|M.gilvum_PYR-GCK          --MADP----VTDQTPESRR-----------------AYTRVLLKLGGEM
Mvan_2220|M.vanbaalenii_PYR-1       --MADPTAEPVAGQSSLIRP-----------------AYSRVLLKLGGEM
MAB_3188c|M.abscessus_ATCC_199      ------------MTRDVSRT-----------------GYKRVLLKLGGEM
Mb2907c|M.bovis_AF2122/97           AGAPASKPEPASTGAASAAQ-----------LSG----YSRVLLKLGGEM
Rv2883c|M.tuberculosis_H37Rv        AGAPASKPEPASTGAASAAQ-----------LSG----YSRVLLKLGGEM
MMAR_1826|M.marinum_M               AGGAAPKPEPASANGVPAAP-----------VSGSVSQYKRVLLKLGGEM
MUL_2074|M.ulcerans_Agy99           AGGAAPKPEPASANGVPAAP-----------VSGSVSQYKRVLLKLGGEM
MLBr_01591|M.leprae_Br4923          AGSAVPKPQLMSANGVSAAAAGRGERLNHAGNPGHRSKYSRVLLKLGGEM
MAV_3733|M.avium_104                -----------------------------------------MLLKLGGEM
                                                                                     *

TH_0271|M.thermoresistible__bu      FGGGQVGLDPDVVQKVAHEIAEVVRSGVQVAVVIGGGNFFRGAQLQQRGL
MSMEG_2540|M.smegmatis_MC2_155      FGGGQVGLDPDVVAQVARQIAEVVRSGAQVAVVIGGGNFFRGAQLQQRGM
Mflv_4124|M.gilvum_PYR-GCK          FGGGQVGLDPDVVALVARQIAEVVRSGAQVAVVIGGGNFFRGAQLQQRGM
Mvan_2220|M.vanbaalenii_PYR-1       FGGGQVGLDPDVVAQVARQIAEVVRSGAQVAVVIGGGNFFRGAQLQQRGM
MAB_3188c|M.abscessus_ATCC_199      FGGGAVGLDPDVVHRVARQIAEVVRTGAEVAVVIGGGNFFRGAQLQQRGM
Mb2907c|M.bovis_AF2122/97           FGGGQVGLDPDVVAQVARQIADVVRGGVQIAVVIGGGNFFRGAQLQQLGM
Rv2883c|M.tuberculosis_H37Rv        FGGGQVGLDPDVVAQVARQIADVVRGGVQIAVVIGGGNFFRGAQLQQLGM
MMAR_1826|M.marinum_M               FGGGQVGLDPDVVAQVARQIAEVVRGGVQVAVVIGGGNFFRGAQLQQRGM
MUL_2074|M.ulcerans_Agy99           FGGGQVGLDPDVVAQVARQIAEVVRGGVQVAVVIGGGNFFRGAQLQQRGM
MLBr_01591|M.leprae_Br4923          FGGGQVGLDLDVVAQVARQIAEVVRGGVQVAVVIGGGNFFRGAQLQQRGM
MAV_3733|M.avium_104                FGGGQVGLDPDVVAQVARQIAEVVRGGVQVAVVIGGGNFFRGAQLQQRGM
                                    **** **** ***  **::**:*** *.::***************** *:

TH_0271|M.thermoresistible__bu      ERSRSDYMGMLGTVMNSLALQDFLQKEGIDTRVQTAITMGQVAEPYIPLR
MSMEG_2540|M.smegmatis_MC2_155      ERTRSDYMGMLGTVMNSLALQDFLQKEGIDTRVQTAITMGQVAEPYIPLR
Mflv_4124|M.gilvum_PYR-GCK          ERTRSDYMGMLGTVMNSLALQDFLQKEGIDTRVQTAITMGQVAEPYIPLR
Mvan_2220|M.vanbaalenii_PYR-1       DRARSDYMGMLGTVMNSLALQDFLQKEGIDTRVQTAITMGQVAEPYIPLR
MAB_3188c|M.abscessus_ATCC_199      ERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYIPLR
Mb2907c|M.bovis_AF2122/97           ERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLR
Rv2883c|M.tuberculosis_H37Rv        ERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLR
MMAR_1826|M.marinum_M               ERTRSDYMGMLGTVMNSLALQDFLEKEGIATRVQTAITMGQVAEPYLPLR
MUL_2074|M.ulcerans_Agy99           ERTRSDYMGMLGTVMNSLALQDFLEKEGIATRVQTAITMGQVAEPYLPLR
MLBr_01591|M.leprae_Br4923          ERTRSDYMGMLGTVMNSLALQDFLEKEGIATRVQTAITMGQVAEPYLPLR
MAV_3733|M.avium_104                ERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLR
                                    :*:*********************:**** ****************:***

TH_0271|M.thermoresistible__bu      AQRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGVY
MSMEG_2540|M.smegmatis_MC2_155      AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGVF
Mflv_4124|M.gilvum_PYR-GCK          AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGIY
Mvan_2220|M.vanbaalenii_PYR-1       AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVF
MAB_3188c|M.abscessus_ATCC_199      ARRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGIF
Mb2907c|M.bovis_AF2122/97           AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVF
Rv2883c|M.tuberculosis_H37Rv        AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVF
MMAR_1826|M.marinum_M               AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVF
MUL_2074|M.ulcerans_Agy99           AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVF
MLBr_01591|M.leprae_Br4923          AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVF
MAV_3733|M.avium_104                AVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGVF
                                    * ***********************************:**********::

TH_0271|M.thermoresistible__bu      TDDPRTNPDAKLITKITHREVIDRGLRVADATAFSLCMDNGMPILVFNLL
MSMEG_2540|M.smegmatis_MC2_155      TDDPRTNPDAELITAISHREVIDRGLKVADATAFSLCMDNGMPILVFNLL
Mflv_4124|M.gilvum_PYR-GCK          TDDPRLNPAAEMLTAISHREVIDRGLKVADATAFSLCMDNGMPILVFNLL
Mvan_2220|M.vanbaalenii_PYR-1       TADPRVDPDAELLIAISHREVIDRGLKVADATAFSLCMDNGMPILVFNLL
MAB_3188c|M.abscessus_ATCC_199      TDDPRANPDAEFLPEITHREVIDRGLQVADATAFSLCMDNRMPILVFNLL
Mb2907c|M.bovis_AF2122/97           AEDPRVNPEAELLTAVSHREVLDRGLRVADATAFSLCMDNGMPILVFNLL
Rv2883c|M.tuberculosis_H37Rv        AEDPRVNPEAELLTAVSHREVLDRGLRVADATAFSLCMDNGMPILVFNLL
MMAR_1826|M.marinum_M               AEDPRVNPHAELLAVISHREVIDRGLRVADATAFSLCMDNGMPILVFNLL
MUL_2074|M.ulcerans_Agy99           AEDPRVNPHAELLAVISHREVIDRGLRVADATAFSLCMDNGMPILVFNLL
MLBr_01591|M.leprae_Br4923          VEDPRVNPEAELLTAISHREVIDRGLRVADATAFSLCMDNGMPILVFNLL
MAV_3733|M.avium_104                SADPRQYPEAELITAISHREVIDRGLRVADATAFSLCMDNGMPILVFNLL
                                      ***  * *:::  ::****:****:************* *********

TH_0271|M.thermoresistible__bu      IDGNIARAVAGEKIGTLVTT
MSMEG_2540|M.smegmatis_MC2_155      TSGNIARAVAGEKIGTLVTT
Mflv_4124|M.gilvum_PYR-GCK          TDGNIARAVAGERIGTLVTT
Mvan_2220|M.vanbaalenii_PYR-1       VDGNIARAVAGEKIGTLVTT
MAB_3188c|M.abscessus_ATCC_199      TEGNIARAVAGEKIGTLVTP
Mb2907c|M.bovis_AF2122/97           TDGNIARAVRGEKIGTLVTT
Rv2883c|M.tuberculosis_H37Rv        TDGNIARAVRGEKIGTLVTT
MMAR_1826|M.marinum_M               TNGNIARAVAGEKIGTLVTT
MUL_2074|M.ulcerans_Agy99           TNGNIARAVAGEKIGTLVTT
MLBr_01591|M.leprae_Br4923          TNGNIARAVAGEKIGTLVTT
MAV_3733|M.avium_104                TNGNIARAVAGEKIGTLVTT
                                     .******* **:******.