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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0194 | - | - | 100% (181) | restriction endonuclease family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2557c | mrr | 2e-05 | 30.77% (117) | restriction system protein mrr |
| M. gilvum PYR-GCK | Mflv_4795 | - | 1e-66 | 69.66% (178) | restriction endonuclease |
| M. tuberculosis H37Rv | Rv2528c | mrr | 2e-05 | 30.77% (117) | restriction system protein mrr |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4727c | - | 8e-24 | 54.29% (105) | hypothetical protein MAB_4727c |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0440 | - | 2e-25 | 46.79% (156) | restriction endonuclease family protein |
| M. smegmatis MC2 155 | MSMEG_1765 | - | 4e-61 | 66.07% (168) | restriction endonuclease family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1653 | - | 1e-65 | 73.84% (172) | restriction endonuclease |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4795|M.gilvum_PYR-GCK ---------------------------------------------MTTLR
Mvan_1653|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0194|M.thermoresistible__bu -----------------------------------------------VSR
MSMEG_1765|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0440|M.avium_104 --------------------------------------------MDKALG
MAB_4727c|M.abscessus_ATCC_199 --------------------------------------MMLQRFRRRAAR
Mb2557c|M.bovis_AF2122/97 MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSG
Rv2528c|M.tuberculosis_H37Rv MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSG
Mflv_4795|M.gilvum_PYR-GCK WRLYAALAIAAGATAHLSGAGWLWTVLAGLLAP-------------VLVV
Mvan_1653|M.vanbaalenii_PYR-1 ----MAWGVAAGGTAYLAGAAPGWSVLVALLAP-------------VATL
TH_0194|M.thermoresistible__bu LKRYLVLAVLAGVAAYLAGLDLIASSLAALTVP-------------AAVA
MSMEG_1765|M.smegmatis_MC2_155 ------MGLAAALTGHLAGAGLPWTVAIGMVVP-------------LALA
MAV_0440|M.avium_104 ALLLLGLGVPWYFTQHTTGS-LPAGCAAGLAGL-------------AAAV
MAB_4727c|M.abscessus_ATCC_199 MRRRLSRAFVTLVVVVLTGPVIALIMWPAVLVYRHTGDPALAALAQAAYL
Mb2557c|M.bovis_AF2122/97 RQRTMYDRVHWSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMA
Rv2528c|M.tuberculosis_H37Rv RQRTMYDRVHWSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMA
. . . :
Mflv_4795|M.gilvum_PYR-GCK AAPSFVRSVVAGAATPGPRENPVDA-------------------------
Mvan_1653|M.vanbaalenii_PYR-1 AAPRFVRATVVGATTPGAGERAVDAGMS----------------------
TH_0194|M.thermoresistible__bu AAPHFLRGVFHGVTTPAPGEDPTAA-------------------------
MSMEG_1765|M.smegmatis_MC2_155 ALPRFVLAVVRGARTPGPRESTAAD-------------------------
MAV_0440|M.avium_104 GALWWLSLQRDRLRADAHRRRDVKHARAG---------------------
MAB_4727c|M.abscessus_ATCC_199 AAPYAVYLGVRGAGWALRRLGEAMVRRRDE---------------AQWQR
Mb2557c|M.bovis_AF2122/97 VLREFPSYIAFRERTKAKQPVDATAKRPSGDDVQVSPEDLIDAALAENRA
Rv2528c|M.tuberculosis_H37Rv VLREFPSYIAFRERTKAKQPVDATAKRPSGDDVQVSPEDLIDAALAENRA
.
Mflv_4795|M.gilvum_PYR-GCK -----------DMSGTEFEDYVARIARTCGVP----VIMTSMTGDWGVDL
Mvan_1653|M.vanbaalenii_PYR-1 -----------AMSGTEFEDHIARIARSCGVP----VIMTPLTGDWGVDL
TH_0194|M.thermoresistible__bu ------------MSGREFEDHIARIARSCGVP----VIMTSVTGDWGVDL
MSMEG_1765|M.smegmatis_MC2_155 ------------MSGLEFEDYVARIARSCGLP----VIMTPLSGDWGVDL
MAV_0440|M.avium_104 ------LRAIDRMSGAEFEDFVAAQLRVAGYV----VTPTAGTGDFGVDL
MAB_4727c|M.abscessus_ATCC_199 YARLSGLAEIDGMSGVDFERFVAARMHSAGWH----IETTRVSGDYGVDL
Mb2557c|M.bovis_AF2122/97 AVEGEILKKALTLSPTGFEDLVIRLLEAMGYGRAGAVERTSASGDAGIDG
Rv2528c|M.tuberculosis_H37Rv AVEGEILKKALTLSPTGFEDLVIRLLEAMGYGRAGAVERTSASGDAGIDG
:* ** : . * : * :** *:*
Mflv_4795|M.gilvum_PYR-GCK IVGHRPH---RLAVQCKRLS--RPVGAGAVQEVVAGAPMQDCTQTMVVTN
Mvan_1653|M.vanbaalenii_PYR-1 IVGHRPH---RLAVQCKRQS--RPVGAGAVQEVVAGAPMQDCTQTMVVTN
TH_0194|M.thermoresistible__bu IIGNRPN---RLAVQCKRQS--RPVGAAAVQEVVAGAPMQDCTRTMVVTN
MSMEG_1765|M.smegmatis_MC2_155 IVGRRPH---RIAIQCKRQS--RPVGAGAVQEVVAGAPMQDCTRTMVVSN
MAV_0440|M.avium_104 IAKKDGV---RMAVQCKRLA--KAVGVAAVQQVVAGARQHGCDRTVVVTN
MAB_4727c|M.abscessus_ATCC_199 IATNRRD---VVAVQCKRYS--KTVGVRAVQEVVAGARHYDCTRAMVVSN
Mb2557c|M.bovis_AF2122/97 IISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGKQGDRGVYITT
Rv2528c|M.tuberculosis_H37Rv IISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGKQGDRGVYITT
* . : :*.** : :.:* :::.... : : ::.
Mflv_4795|M.gilvum_PYR-GCK HEFTPAARKLAELH--GCTLVGGADLPRLRSTIRRLTRPAEPPSSSAPRP
Mvan_1653|M.vanbaalenii_PYR-1 HEFTPAARKLAELH--GCELVGGADLPRLRSTIRRLT------SS-----
TH_0194|M.thermoresistible__bu HDFTPAARKLAERH--GCELVSGRDLPRLRSIIRRLTV------------
MSMEG_1765|M.smegmatis_MC2_155 NEFTPAARKLAELH--GCELVGGDDLPRLRSILRRAAAD----GSRA---
MAV_0440|M.avium_104 QTFTKAARRLAITH--RCRLVG---RTQLRSWTRVAPIPVRGPRVS----
MAB_4727c|M.abscessus_ATCC_199 QDFTRQAQALAATS--RCELIGRDRLPRWLVHGEKSAFANAAPPR-----
Mb2557c|M.bovis_AF2122/97 SSFSRGARQEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
Rv2528c|M.tuberculosis_H37Rv SSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
*: *: * *:. .. .
Mflv_4795|M.gilvum_PYR-GCK PP----
Mvan_1653|M.vanbaalenii_PYR-1 ------
TH_0194|M.thermoresistible__bu ------
MSMEG_1765|M.smegmatis_MC2_155 ------
MAV_0440|M.avium_104 ------
MAB_4727c|M.abscessus_ATCC_199 ------
Mb2557c|M.bovis_AF2122/97 DFFDGL
Rv2528c|M.tuberculosis_H37Rv DFFDGL