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M. tuberculosis H37Rv Rv2528c (mrr)

TIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWSLTHMSQAGL
LDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQPVDATAKRPSGDDVQVSPEDLI
DAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMGYGRAGAVERTSASGDAGIDGIISQDPLGLDR
IYVQAKRYAVDQTIGRPKIHEFAGALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLV
RYRVGVQAVQTVELLRLDEDFFDGL*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv2528c	mrr	-	100% (306)	PROBABLE RESTRICTION SYSTEM PROTEIN MRR

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb2557c	mrr	1e-171	99.67% (306)	restriction system protein mrr
M. gilvum PYR-GCK	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	-	-	-	-	-
M. thermoresistible (build 8)	TH_3853	-	3e-07	29.53% (149)	PUTATIVE -
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	-	-	-	-	-

CLUSTAL 2.0.9 multiple sequence alignment


Rv2528c|M.tuberculosis_H37Rv        MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSG
Mb2557c|M.bovis_AF2122/97           MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSG
TH_3853|M.thermoresistible__bu      ----------MQVGDYVVTYSPANRTYLVGRITGPSELH-----------
                                                :  *:.  .. . . ::. ::.   *            

Rv2528c|M.tuberculosis_H37Rv        RQRTMYDRVHWSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMA
Mb2557c|M.bovis_AF2122/97           RQRTMYDRVHWSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMA
TH_3853|M.thermoresistible__bu      --------LEWEAEGMNLSRPVEWMPR------EVDRDSLRTVSKNSLGS
                                            :.*.   *. :  ::  .*      :..*: *:: .:.   :

Rv2528c|M.tuberculosis_H37Rv        VLREFPSYIAFRERTKAKQPVDATAKRPSGDDVQVSPEDLIDAALAENRA
Mb2557c|M.bovis_AF2122/97           VLREFPSYIAFRERTKAKQPVDATAKRPSGDDVQVSPEDLIDAALAENRA
TH_3853|M.thermoresistible__bu      TLTIFKLSNSVRDELLALARGDAS---PPVEPEVVDDEDVVDP-LSDYEA
                                    .*  *    :.*:.  *    **:   *. :   *. **::*. *:: .*

Rv2528c|M.tuberculosis_H37Rv        AVEGEILKKALTLSPTGFEDLVIRLLEAMGYGRAGAVERTSASGDAGIDG
Mb2557c|M.bovis_AF2122/97           AVEGEILKKALTLSPTGFEDLVIRLLEAMGYGRAGAVERTSASGDAGIDG
TH_3853|M.thermoresistible__bu      IAFERIKDLVSRLDWKDFQDLVAGILRAMGY----KTQVSPPGSDLGRDI
                                     .  .* . .  *. ..*:***  :*.****     .: :....* * * 

Rv2528c|M.tuberculosis_H37Rv        IISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGKQGDRGVYITT
Mb2557c|M.bovis_AF2122/97           IISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGKQGDRGVYITT
TH_3853|M.thermoresistible__bu      LASPDGFGFEQPRIVVEVKHRKESVSSYGIRSFVGG--RHKDDRCLYVST
                                    : * * :*:::  : .:    .:::.   *:.*.*.   ::.** :*::*

Rv2528c|M.tuberculosis_H37Rv        SSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
Mb2557c|M.bovis_AF2122/97           SSFSRGARQEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
TH_3853|M.thermoresistible__bu      GGFTRDARYEADRSSIPVVLWTVEELTKALIDN-YDNTDGKTKALVSLRT
                                    ..*:*.** **:* .  : *    .*:: *:    .    :*  *: *  

Rv2528c|M.tuberculosis_H37Rv        DFFDGL--
Mb2557c|M.bovis_AF2122/97           DFFDGL--
TH_3853|M.thermoresistible__bu      FYAPAADV
                                     :  .