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M. thermoresistible (build 8) TH_0111 (aroE)

annotation: PROBABLE SHIKIMATE 5-DEHYDROGENASE AROE (5-DEHYDROSHIKIMATE REDUCTASE)
coordinates: 209246 - 210013
length: 256

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0111 aroE - 100% (256) PROBABLE SHIKIMATE 5-DEHYDROGENASE AROE (5-DEHYDROSHIKIMATE REDUCTASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2582c aroE 3e-99 71.48% (256) shikimate 5-dehydrogenase
M. gilvum PYR-GCK Mflv_3760 aroE 9e-92 68.22% (258) shikimate 5-dehydrogenase
M. tuberculosis H37Rv Rv2552c aroE 3e-99 71.48% (256) shikimate 5-dehydrogenase
M. leprae Br4923 MLBr_00515 aroE 4e-92 64.50% (262) shikimate 5-dehydrogenase
M. abscessus ATCC 19977 MAB_2848c aroE 4e-82 60.98% (264) shikimate 5-dehydrogenase
M. marinum M MMAR_2173 aroE 1e-99 71.88% (256) shikimate 5-dehydrogenase AroE
M. avium 104 MAV_3428 aroE 8e-93 67.06% (255) shikimate 5-dehydrogenase
M. smegmatis MC2 155 MSMEG_3028 aroE 1e-103 73.08% (260) shikimate 5-dehydrogenase
M. ulcerans Agy99 MUL_1757 aroE 2e-98 71.09% (256) shikimate 5-dehydrogenase
M. vanbaalenii PYR-1 Mvan_2643 aroE 1e-101 74.03% (258) shikimate 5-dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3760|M.gilvum_PYR-GCK          MSSTPAADRP--------------------RRAAVLGSPIAHSRSPQLHL
Mvan_2643|M.vanbaalenii_PYR-1       MMS----AGP--------------------RRAAVLGSPIAHSRSPQLHL
Mb2582c|M.bovis_AF2122/97           MSSTARDERR-------------------SQKAGVLGSPIAHSRSPQLHL
Rv2552c|M.tuberculosis_H37Rv        MSEGPK-------------------------KAGVLGSPIAHSRSPQLHL
MLBr_00515|M.leprae_Br4923          MSLTACANKG-------------------PRKAGIIGSPIAHSRSPHLHL
MAV_3428|M.avium_104                MSSTAPPASGDRKRGGAGRSGSPPGQAAGPRRAAVLGKPIAHSKSPQLHL
MMAR_2173|M.marinum_M               MSSGQEHSQPPR-----------------GRKAAVLGSPIAHSRSPQLHL
MUL_1757|M.ulcerans_Agy99           MSSGQEHNQPPR-----------------GRKAAVLGSPIAHSRSPQLHL
TH_0111|M.thermoresistible__bu      ----------------------------------VLGSPIAHSRSPQLHL
MSMEG_3028|M.smegmatis_MC2_155      MPGRRPAAPGE------------------PRKAAVLGSPIAHSRSPQLHL
MAB_2848c|M.abscessus_ATCC_199      MLAEIR-------------------------RAAVLGSPIGHSRSPDLHV
                                                                      ::*.**.**:**.**:

Mflv_3760|M.gilvum_PYR-GCK          AAYAALGLSSWRYDRIECGEDELPGFVAGLGDEWVGLSVTMPGKFAALRC
Mvan_2643|M.vanbaalenii_PYR-1       AAYRALGLTDWTYERIECTGEQLPGVVAGFGPEWVGVSVTMPGKFAALRV
Mb2582c|M.bovis_AF2122/97           AAYRALGLHDWTYERIECGAAELPVVVGGFGPEWVGVSVTMPGKFAALRF
Rv2552c|M.tuberculosis_H37Rv        AAYRALGLHDWTYERIECGAAELPVVVGGFGPEWVGVSVTMPGKFAALRF
MLBr_00515|M.leprae_Br4923          AAYRALRLHDWTYERIECDAEELPTVVSGFGPQWVGVSVTMPGKFAALRF
MAV_3428|M.avium_104                AAYRALGLHDWTYERIECDADQLPGVVGGFGPEWVGVSVTMPGKFAALRF
MMAR_2173|M.marinum_M               AAYRALGLTDWTYQRIECDAAQLPAVVGGFGPEWVGVSVTMPGKFAALQF
MUL_1757|M.ulcerans_Agy99           AAYRALGLTDWTYQRIECDAAQLPAVVGGFGPEWVGVSVTMPGKFAALQF
TH_0111|M.thermoresistible__bu      AAYRALGLTGWTYERIECDAEQLPVLVGGFGPEWVGVSVTMPGKFAALTF
MSMEG_3028|M.smegmatis_MC2_155      AAYRALGLTDWTYERIECTAEQLPGLVEAAGPEWVGFSVTMPGKFAALQF
MAB_2848c|M.abscessus_ATCC_199      AAYRALGLTGWTYERIECTAEQLPDVVGGAGPEWVGFSVTMPGKFAALRF
                                    *** ** * .* *:****   :** .* . * :***.***********  

Mflv_3760|M.gilvum_PYR-GCK          ADEATERARLVGSANTLVHTA-TGWRADNTDIDGVAGALADAG---VSGS
Mvan_2643|M.vanbaalenii_PYR-1       ADEATDRARMVGSANTLVRSS-AGWRADNTDIDGVVGALSGVQ---VTDR
Mb2582c|M.bovis_AF2122/97           ADERTARADLVGSANTLVRTP-HGWRADNTDIDGVAGALGAA-----AGH
Rv2552c|M.tuberculosis_H37Rv        ADERTARADLVGSANTLVRTP-HGWRADNTDIDGVAGALGAA-----AGH
MLBr_00515|M.leprae_Br4923          ADEHTARASLVGSANTLLRTQ-RGWRADNTDIDGVAGALAAIGP--LAGR
MAV_3428|M.avium_104                ADERTERARRVGSANTLVRTA-TGWRADNTDIDGVAGALGAA-----SGW
MMAR_2173|M.marinum_M               ADERTARAELVGSANTLVRTP-RGWRADNTDIDGVAGALGQA-----SGP
MUL_1757|M.ulcerans_Agy99           ADERTARAELVGSANTLVRTP-RGWRADNTDIDGVAGALGQA-----SGP
TH_0111|M.thermoresistible__bu      ADQRTARAELVGSANTLVRRD-GGWLADNTDIDGVKGALGAV-----GEH
MSMEG_3028|M.smegmatis_MC2_155      ADQRTDRAELVGSANTLVRTEAGGWRADNTDVDGVAGALGTA-----GEA
MAB_2848c|M.abscessus_ATCC_199      ASTSTERARSIGAANTLVRSG-DGWHADNTDVDGVSGALAGAGIDPAGQS
                                    *.  * **  :*:****::    ** *****:*** ***.          

Mflv_3760|M.gilvum_PYR-GCK          AVVVGSGGTAPAVVAGLVQLGAHHVTVVARNAEKAQGLVALGRRCGATTE
Mvan_2643|M.vanbaalenii_PYR-1       AMVIGSGGTAPAVVVGLVTLGARFVTVAARHADKASALVELAVRCGARAG
Mb2582c|M.bovis_AF2122/97           ALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATR
Rv2552c|M.tuberculosis_H37Rv        ALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATR
MLBr_00515|M.leprae_Br4923          ALVCGSGGTAPAAVMGLAELGVTDITVLARNPDKASRLVDLGVQVGVATR
MAV_3428|M.avium_104                ALVCGSGGTAPAAVAGLAQLGVAGITVVARNPDKAARLVRLGDELGVPTR
MMAR_2173|M.marinum_M               AIVCGSGGTAPAAVVGLAELGVTEITIAARNADKAARLVDLGARLGVASR
MUL_1757|M.ulcerans_Agy99           AIVCGSGGTAPAAVVGLAELGVTEITIAARNADKAARLVDLGARLGVASR
TH_0111|M.thermoresistible__bu      VMVVGSGGTAPAAVVAVVESGARQVTVAARNREKAAPLVELAERLGASAR
MSMEG_3028|M.smegmatis_MC2_155      ALVIGSGGTAPAAVVGLAEMGVQHITIVARNADKAAALVDLAGRCGAQGD
MAB_2848c|M.abscessus_ATCC_199      AVIVGAGGTARPAIVALAAMGVRALTVVARDAGRAQGVLELAEHLGLRAS
                                    .:: *:**** ..: .:.  *.  :*: **.  :*  :: *. . *    

Mflv_3760|M.gilvum_PYR-GCK          WVDLTGDDVTGAVAAADVVVNTVPADAVAPYAPRLAGTPVLLDAIYDPWP
Mvan_2643|M.vanbaalenii_PYR-1       WVDLQHGRLAEEVAGVEVVVNTVPADAVAPHAAALAGTPVLLDAIYDPWP
Mb2582c|M.bovis_AF2122/97           FCAFDSGGLADAVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWP
Rv2552c|M.tuberculosis_H37Rv        FCAFDSGGLADAVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWP
MLBr_00515|M.leprae_Br4923          LCGLDSGGLADEVKAAEVLVSTVPADVAARYVDVFATVPVLLDAIYDPWP
MAV_3428|M.avium_104                FCALDGAGLADEVAAAEVLVSTLPAEVAERYAGTLARVGVLLDAVYDPWP
MMAR_2173|M.marinum_M               FCGLDDPELGERAASAAALVSTIPAEVASRYAATFATVPVLLDAIYNPWP
MUL_1757|M.ulcerans_Agy99           FCGLDDPELGERAASAAALVSTIPAEVASRYAATFATVPVVLDAIYNSWP
TH_0111|M.thermoresistible__bu      WQDLAG----VTAAGVDAVVSTIPADAAARYAAALSATPVLVDAIYDPWP
MSMEG_3028|M.smegmatis_MC2_155      WCDIAGPALTDAVAQASAAVSTIPADAAAGYAPTLAAVPRLLDAIYNPWP
MAB_2848c|M.abscessus_ATCC_199      VLSFTDAELSSVCQAAGVLVSTVPAEAAAPYARSLAAAPAILDVIYHPWP
                                       :           . . *.*:**:..  :.  ::    ::*.:*..**

Mflv_3760|M.gilvum_PYR-GCK          TPLAAAVTAAGGRVISGLEMLLNQAFAQVEQFTGMPAPQKAMRGALGLA-
Mvan_2643|M.vanbaalenii_PYR-1       TPLAAAVQAAGGQVISGLEMLLNQAFTQVEQFTGLPAPKEAMRAALESA-
Mb2582c|M.bovis_AF2122/97           TPLAAAVGSAGGRVISGLQMLLHQAFAQVEQFTGLPAPREAMTCALAALD
Rv2552c|M.tuberculosis_H37Rv        TPLAAAVGSAGGRVISGLQMLLHQAFAQVEQFTGLPAPREAMTCALAALD
MLBr_00515|M.leprae_Br4923          TPLVAAVSAAGGRVISGLQMLLHQAFAQVEQFTGMPAPREAMACALAGLH
MAV_3428|M.avium_104                TPLAAAVSAAGGRVISGMQMLLHQAFAQVEQFTGLPAPREAMTCAAADAD
MMAR_2173|M.marinum_M               TPLAAAVAAAGGRVISGLHMLLHQAFAQVEQFTGLPAPRAAMTCALEALD
MUL_1757|M.ulcerans_Agy99           TPLAAAVAAAGGRVISGLHMLLHQAFAQVEQFTGLPAPRAAMTCALEALD
TH_0111|M.thermoresistible__bu      TPLAAAVAEAGGRVISGLEMLLNQAFTQVELFTGRPAPKEAMRAALNQP-
MSMEG_3028|M.smegmatis_MC2_155      TPLATAVQAAGGEVISGLQMLLNQAYSQVELFTGRPAPKEAMRAALEEP-
MAB_2848c|M.abscessus_ATCC_199      TTLAAAAQRRGAVVVGGLDMLLNQAFTQVELFTGLSAPRAAMAAALH---
                                    *.*.:*.   *. *:.*:.***:**::*** *** .**: **  *

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0111	aroE	-	100% (256)	PROBABLE SHIKIMATE 5-DEHYDROGENASE AROE (5-DEHYDROSHIKIMATE REDUCTASE)