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TAIGLTDVEVAARLAEGKSNDIPERATRRVAQIVRANVFTRINAILGVLLLIVLATGSVINGMFGLLIIA NSIIGMIQELRAKQTLDNLAILGQAKPLVRRQSGTRTMSPSEVVLDDVIELGPGDQVVVDGEVLEQDNLE IDESLLTGEADSIAKHVGEQVMSGSFVVAGSGAYRATKVGHEAYAAKLAAEASKFTLVKSELRSGINKIL QFITYLLIPAGLLTIYTQLFTTHAGWRDSVLRTVGALVPMVPEGLVLITSIAFAVGVVRLGQRQCLVQEL PAIEGLARVDVVCADKTGTLTETGMRVSDVDELIADQHGAVADVLAFLAAADARPNASMQAIAQAFPSPP DWTSTATAPFKSATKWSGISFRDHGNWVIGAPDVLLDSASEAAREAERIGAQGLRILLLGVAAVAVDDPC APGQVTPAALVILEQKVRPDARETMEYFAAQNVSVKVISGDNAVSVGAVAAKLGLQGQTMDARQLPSEQP ELADVLDTYITFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIGVAMGTGSPASRAVAQIV LLDNRFATLPYVVGEGRRVIRNIERVANLFLTKAVYSALLALLVGIECLFAKPLGADPLLYPFQPIHVTI AAWFTIGIPSFILSLAPNDERAYPGFVRRVLTSALPSGLVVGVATFVSYLTAYPGRHSTWQEQTQASTAA LITLLVTALWVLAVVARPYRWWRLGLVIACGLAYVAIFSLPLAQRKFFLDPSNLATTSIALGIGVLGAAL IEAMWWLRARALGLRPRVWR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0233 | ctpE | - | 100% (791) | metal cation transporter ATPase p-type CtpE |
| M. ulcerans Agy99 | MUL_1254 | - | 6e-58 | 28.47% (685) | metal cation transporter p-type ATPase a |
| M. ulcerans Agy99 | MUL_0612 | ctpF | 2e-55 | 25.51% (886) | metal cation-transporting p-type ATPase F, CtpF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0932 | ctpE | 0.0 | 83.76% (788) | metal cation transporter ATPase P-type CtpE |
| M. gilvum PYR-GCK | Mflv_1758 | - | 0.0 | 76.87% (787) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
| M. tuberculosis H37Rv | Rv0908 | ctpE | 0.0 | 83.76% (788) | metal cation transporter ATPase P-type CtpE |
| M. leprae Br4923 | MLBr_02671 | - | 2e-48 | 27.36% (870) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_0962 | - | 0.0 | 71.65% (790) | cation-transporting ATPase E |
| M. marinum M | MMAR_4622 | ctpE | 0.0 | 98.61% (791) | metal cation transporter ATPase p-type CtpE |
| M. avium 104 | MAV_1031 | - | 0.0 | 81.70% (787) | cation-transporting ATPase Exp7 |
| M. smegmatis MC2 155 | MSMEG_5636 | - | 0.0 | 78.38% (791) | P-type ATPase - metal cation transport |
| M. thermoresistible (build 8) | TH_0097 | - | 0.0 | 74.43% (790) | P-type ATPase - metal cation transport |
| M. vanbaalenii PYR-1 | Mvan_4989 | - | 0.0 | 76.62% (800) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 MKIPHVTDPVSNMVGGMAQVVRASTHAATGAVNTMQMLASPVAEFAWPVV
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 QSVAKSTGRALGTGHSPNFANRVDPPVRWHNGQRVHLDLDPLLPFPRWHE
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 YAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNADSDVVLGKVRDVVIA
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 LAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALSAAVTGWV
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 TRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSITTAAASGL
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 TQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQAPVVPVIS
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 SAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKGPVESYVD
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 SAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFAATLGRGL
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 ANAGQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGNTPGWDDDR
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 VYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPVQGREHADL
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 VVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTEDLSASVG
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 ATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAALAIADVGVA
MUL_0233|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4622|M.marinum_M --------------------------------------------------
Mb0932|M.bovis_AF2122/97 --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1031|M.avium_104 --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0097|M.thermoresistible__bu --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02671|M.leprae_Br4923 LDDPHAATPWTADIITGTDLAAAVRILSALPVARSASESSVHLAQGGTTL
MUL_0233|M.ulcerans_Agy99 --------------------MT-----AIGLTDVEVAARLAEGKSNDIPE
MMAR_4622|M.marinum_M --------------------MT-----AIGLTDAEVAARLAEGKSNDIPE
Mb0932|M.bovis_AF2122/97 --------------------MTRSASATAGLTDAEVAQRVAEGKSNDIPE
Rv0908|M.tuberculosis_H37Rv --------------------MTRSASATAGLTDAEVAQRVAEGKSNDIPE
MAV_1031|M.avium_104 --------------------MN------TGLTDAEVAQRVAHGQSNAVRQ
Mflv_1758|M.gilvum_PYR-GCK -----------------MSAPS--DNLVAGLSDAEVAARVAEGKTNDVPT
MSMEG_5636|M.smegmatis_MC2_155 --------------------MT--TMAAAGLTDAEVAQRIAEGKTNDVPT
Mvan_4989|M.vanbaalenii_PYR-1 --------------------MT--VSVVTGLSEAEVAQRVAEGKTNDVPT
TH_0097|M.thermoresistible__bu --------------------VT--TTLAPGLSDAEVAQRVAAGQTNDVPT
MAB_0962|M.abscessus_ATCC_1997 -------------------MATIEGLTISGLTAAEVAERVAQGKTNDVPS
MLBr_02671|M.leprae_Br4923 AGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVVSASKVLRLPD
. : . *: :: .: :
MUL_0233|M.ulcerans_Agy99 RATRRVAQIVRAN---VFTRINAILG------------------------
MMAR_4622|M.marinum_M RATRSVAQIVRAN---VFTRINAILG------------------------
Mb0932|M.bovis_AF2122/97 RVTRTVGQIVRAN---VFTRINAILG------------------------
Rv0908|M.tuberculosis_H37Rv RVTRTVGQIVRAN---VFTRINAILG------------------------
MAV_1031|M.avium_104 RATRSITDIVRAN---VFTRINAILG------------------------
Mflv_1758|M.gilvum_PYR-GCK RAARSVSEIIRGN---VFTRINAILG------------------------
MSMEG_5636|M.smegmatis_MC2_155 RAARTVSEIVRAN---VFTRINAILG------------------------
Mvan_4989|M.vanbaalenii_PYR-1 RAARSVSEIVRGN---VFTRINAILG------------------------
TH_0097|M.thermoresistible__bu RAARTTGEIIRAN---VFTRINGILG------------------------
MAB_0962|M.abscessus_ATCC_1997 RAARSVSDIVRAN---VFTRINAILG------------------------
MLBr_02671|M.leprae_Br4923 PTPQPLTAWHALDPEIVYSRLAGVTQPLAVEPGTPDWRRRLDDLSYTRAL
..: : *::*: .:
MUL_0233|M.ulcerans_Agy99 --------------------------VLLLIVLATGSVINGMFGLLIIA-
MMAR_4622|M.marinum_M --------------------------VLLLIVLATGSVINGMFGLLIIA-
Mb0932|M.bovis_AF2122/97 --------------------------VLLLIVLATGSLINGMFGLLIIA-
Rv0908|M.tuberculosis_H37Rv --------------------------VLLLIVLATGSLINGMFGLLIIA-
MAV_1031|M.avium_104 --------------------------VLLLIVLATGSVINGMFGLLIIA-
Mflv_1758|M.gilvum_PYR-GCK --------------------------VLFVIVLSTGSLINGAFGLLIIA-
MSMEG_5636|M.smegmatis_MC2_155 --------------------------VLFVIVLSTGSVINGAFGLLIIA-
Mvan_4989|M.vanbaalenii_PYR-1 --------------------------VLLIIVLATGSVINGAFGLLIIA-
TH_0097|M.thermoresistible__bu --------------------------VLFLIVLSTGSIINGAFGLLIIA-
MAB_0962|M.abscessus_ATCC_1997 --------------------------VLLIIVLSTGSIINGAFGLLIIA-
MLBr_02671|M.leprae_Br4923 SPLRKPVTKLARLASATRQEFADPLTPILAVGAAASAIVGSNIDALLVAG
:: : ::.:::.. :. *::*
MUL_0233|M.ulcerans_Agy99 ----NSIIGMIQELRAKQTLDNLAILG---------QAKPLVRRQSGT--
MMAR_4622|M.marinum_M ----NSIIGMIQELRAKQTLDNLAILG---------QAKPLVRRQSGT--
Mb0932|M.bovis_AF2122/97 ----NSVIGMVQEIRAKQTLDKLAIIG---------QAKPLVRRQSGT--
Rv0908|M.tuberculosis_H37Rv ----NSVIGMVQEIRAKQTLDKLAIIG---------QAKPLVRRQSGT--
MAV_1031|M.avium_104 ----NSVVGMVQEIRAKQTLDKLAIVG---------QAKPMVRRQSGT--
Mflv_1758|M.gilvum_PYR-GCK ----NSAIGIIQELRAKQTLDKLAIVG---------QAKPLVRRQSGT--
MSMEG_5636|M.smegmatis_MC2_155 ----NSAIGIIQEIRAKQTLDKLAIVG---------QAKPTVRRQSGT--
Mvan_4989|M.vanbaalenii_PYR-1 ----NSAIGIIQELRAKQTLDKLAIVG---------QAKPLVRRKSGTGS
TH_0097|M.thermoresistible__bu ----NSAVGMIQELRAKRTLDNLAIIG---------QAKPMVRRRSGT--
MAB_0962|M.abscessus_ATCC_1997 ----NSAVGIIQELRAKQILDKLAIVG---------QTRPLVRRDGAA--
MLBr_02671|M.leprae_Br4923 VMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTRRRLEAAQ
*: * :*.:**: :* : . .** :
MUL_0233|M.ulcerans_Agy99 -----RTMSPSEVVLDDVIELGPGDQVVVDGEVLEQDNLEIDESLLTGEA
MMAR_4622|M.marinum_M -----RTMSPSEVVLDDVIELGPGDQVVVDGEVLEQDNLEIDESLLTGEA
Mb0932|M.bovis_AF2122/97 -----RTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEA
Rv0908|M.tuberculosis_H37Rv -----RTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEA
MAV_1031|M.avium_104 -----HALPPDEVVLDDIIELGPGDQVVVDGEIVEEANLEVDESLLTGEA
Mflv_1758|M.gilvum_PYR-GCK -----QPMPPSEVVLDDVIELGPGDQIVVDGVILEETNLEVDESLLTGEA
MSMEG_5636|M.smegmatis_MC2_155 -----RAVLPSEVVLDDIIELGPGDQIVVDGEVVEETNLEVDESLLTGEA
Mvan_4989|M.vanbaalenii_PYR-1 VS---LPLAPSEVVLDDVIELGPGDQIVVDGVILEESNLEIDESLLTGEA
TH_0097|M.thermoresistible__bu -----RALAPSEVVLDDIIELGPGDQIVVDGEVVEAANLEIDESLLTGEA
MAB_0962|M.abscessus_ATCC_1997 -----TALAPNEVVLDDIIELGPGDQIVVDGEVIEESALEIDESLLTGEA
MLBr_02671|M.leprae_Br4923 HATRTVTVSAKSLRAGDVIDLAAPEVVPADARVLVAEDLEVDESLLTGES
. ...: .*:*:*.. : : .*. :: **:********:
MUL_0233|M.ulcerans_Agy99 DSIAKHVG----EQVMSGSFVVAGSGAYR-ATKVGHEAYAAKLAAEASKF
MMAR_4622|M.marinum_M DSIAKHVG----EQVMSGSFVVAGSGAYR-ATKVGHEAYAAKLAAEASKF
Mb0932|M.bovis_AF2122/97 DPIAKDAG----DTVMSGSFVVSGAGAYR-ATKVGSEAYAAKLAAEASKF
Rv0908|M.tuberculosis_H37Rv DPIAKDAG----DTVMSGSFVVSGAGAYR-ATKVGSEAYAAKLAAEASKF
MAV_1031|M.avium_104 DPIAKAVG----DSVMSGSFVVAGTGAYR-ATRVGSQAYAARLAEEASKF
Mflv_1758|M.gilvum_PYR-GCK DAIAKDAG----DHVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
MSMEG_5636|M.smegmatis_MC2_155 DPIAKDAG----DPVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
Mvan_4989|M.vanbaalenii_PYR-1 DAIAKGID----DHVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
TH_0097|M.thermoresistible__bu DPIPKEPG----DQVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
MAB_0962|M.abscessus_ATCC_1997 DAIEKTIG----SQVLSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
MLBr_02671|M.leprae_Br4923 LPVDKRVDPVAINDADRASMLFEGSAIVAGHARAIVVATGVGTAAHRAIS
.: * . . . .*::. *:. ::. * .. * . :
MUL_0233|M.ulcerans_Agy99 TLVKSELRSGINKILQFITYLLIP---AGLLTIYTQLFTTHAGWRDSVLR
MMAR_4622|M.marinum_M TLVKSELRSGINKILQFITYLLIP---AGLLTIYTQLFTTHAGWRDSVLR
Mb0932|M.bovis_AF2122/97 TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHVGWRESVLR
Rv0908|M.tuberculosis_H37Rv TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHVGWRESVLR
MAV_1031|M.avium_104 TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHAGWQKSVLR
Mflv_1758|M.gilvum_PYR-GCK TLVRSELRNGINQILRFITYLLIP---AGALIIYTQLFTTDSGWRESVLR
MSMEG_5636|M.smegmatis_MC2_155 TLVKSELRNGINKILQFITYLLVP---AGLLTIYTQLFTTDAGWREAVLR
Mvan_4989|M.vanbaalenii_PYR-1 TLVKSELRNGINKILQFITYLLVP---AGALTIYTQLFTTDAGWRRAVLA
TH_0097|M.thermoresistible__bu TLVKSDLRNGINTILRFITYLLIP---AGLLTIYTQLFTTDADWRRAVLA
MAB_0962|M.abscessus_ATCC_1997 TLVHSELRNGINKILQFITYLLLP---AGALIIYTQLFTTDDSWQESVLR
MLBr_02671|M.leprae_Br4923 AVADVEVSAGVQARLRELTSKVLPLTLAGGAAVTGLALLRRASLRQAVAD
::. :: *:: *: :* ::* ** : : . : :*
MUL_0233|M.ulcerans_Agy99 TVGALVPMVPEGLVLITSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
MMAR_4622|M.marinum_M TVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
Mb0932|M.bovis_AF2122/97 MVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
Rv0908|M.tuberculosis_H37Rv MVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
MAV_1031|M.avium_104 TVGALVPMVPEGLVLLTSVAFAVGVVRLGQRRCLVQELPAIEGLARVDVV
Mflv_1758|M.gilvum_PYR-GCK MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV
MSMEG_5636|M.smegmatis_MC2_155 MVGALVPMVPEGLVLMTSIAFAVGVVRLGRRQCLVNELPAIEGLARVDVV
Mvan_4989|M.vanbaalenii_PYR-1 MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV
TH_0097|M.thermoresistible__bu MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV
MAB_0962|M.abscessus_ATCC_1997 MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVQELPAIEGLARVDTV
MLBr_02671|M.leprae_Br4923 GVAIAVAAVPEGLPLVATLSQLAAAQRLTAKGALVRSPRTIEALGRVDTI
*. *. ***** *::::: ... ** : .**.. :**.*.***.:
MUL_0233|M.ulcerans_Agy99 CADKTGTLTETGMRVSDVDELI---------ADQHGAVADVLAFLAAADA
MMAR_4622|M.marinum_M CADKTGTLTETGMRVSDVDELI---------ADQHGAVADVLAFLAAADA
Mb0932|M.bovis_AF2122/97 CADKTGTLTESGMRVCEVEELDG--------AGRQESVADVLAALAAADA
Rv0908|M.tuberculosis_H37Rv CADKTGTLTESGMRVCEVEELDG--------AGRQESVADVLAALAAADA
MAV_1031|M.avium_104 CADKTGTLTESGMRVARVDELD---------GSGHDRIADVLAALAAADP
Mflv_1758|M.gilvum_PYR-GCK CADKTGTLTENGMRVSDLKVLES------------RSVTDVLAQLAADDA
MSMEG_5636|M.smegmatis_MC2_155 CADKTGTLTENGMRVSDLKSLTE------------GHVADVLAQLASDDA
Mvan_4989|M.vanbaalenii_PYR-1 CADKTGTLTENGMRVSEVKRIDARPTGEERSDRGMGTVADVLAQLAADDP
TH_0097|M.thermoresistible__bu CADKTGTLTENGMRVAELRHLTE--------SGDRSRVEAVLASLAADDP
MAB_0962|M.abscessus_ATCC_1997 CADKTGTLTENGMRLADVHFPDR---------DGDEDALAVLAQLAADDP
MLBr_02671|M.leprae_Br4923 CFDKTGTLTENRLRVVCAVPNTR-MPHDPLPDITDPHSAAVLRDAARAST
* ********. :*: ** * ..
MUL_0233|M.ulcerans_Agy99 RPNAS------------MQAIAQAFPSPPDWTSTATAPFKSATKWSGISF
MMAR_4622|M.marinum_M RPNAS------------MQAIAQAFPSPPDWTPTATAPFKSATKWSGISF
Mb0932|M.bovis_AF2122/97 RPNAS------------MQAIAEAFHSPPGWVVAANAPFKSATKWSGVSF
Rv0908|M.tuberculosis_H37Rv RPNAS------------MQAIAEAFHSPPGWVVAANAPFKSATKWSGVSF
MAV_1031|M.avium_104 RPNAS------------MRAIAQTYSRPPGWTVTATAPFKSATKWSGVSF
Mflv_1758|M.gilvum_PYR-GCK RPNAS------------MAAIAEAYAVPPGWTATATAPFKSATKWSGASY
MSMEG_5636|M.smegmatis_MC2_155 RPNAS------------MAAIAEAYQTPPGWSATATAPFKSATKWSGTSY
Mvan_4989|M.vanbaalenii_PYR-1 RPNAS------------MAAIAEAYKMPPGWTATATAPFKSATKWSGTSY
TH_0097|M.thermoresistible__bu RPNAS------------MQAIAEAYPDPPGWAATAIAPFKSALKWSGVSY
MAB_0962|M.abscessus_ATCC_1997 RPNAS------------IAAIAEAYDTPPGWETTAIAPFSSAKKWSGASY
MLBr_02671|M.leprae_Br4923 QPHDGQGHTHATDEAILTAASSLNSHTDSTWSLIAEVPFESSRGYAAAIG
:*: . * : . * * .**.*: ::.
MUL_0233|M.ulcerans_Agy99 RDHGN-----WVIGAPDVLLDSASEAAREAERIGAQ---------GLRIL
MMAR_4622|M.marinum_M RDHGN-----WVIGAPDVLLDSASDAAREAERIGAQ---------GLRIL
Mb0932|M.bovis_AF2122/97 RDHGN-----WVIGAPDVLLDPASVAARQAERIGAQ---------GLRVL
Rv0908|M.tuberculosis_H37Rv RDHGN-----WVIGAPDVLLDPASVAARQAERIGAQ---------GLRVL
MAV_1031|M.avium_104 AGHGD-----WVMGAPDVLLDSCSAAAGQAERLGAQ---------GLRVL
Mflv_1758|M.gilvum_PYR-GCK AEHGN-----WVIGAPDVLLDPASPVAEDAERIGAR---------GLRVL
MSMEG_5636|M.smegmatis_MC2_155 GEHGN-----WVIGAPDVLLDPASPVAEEAERIGAQ---------GLRVL
Mvan_4989|M.vanbaalenii_PYR-1 GDHGN-----WVIGAPDVLLDPTSTAAEEAERIGAQ---------GLRVL
TH_0097|M.thermoresistible__bu GEHGN-----WVIGAPDVLLDPASPAARQAEEIGSR---------GLRVL
MAB_0962|M.abscessus_ATCC_1997 GEHGN-----WVIGAPDVLLDPADAIATAAEEIGAR---------GLRVL
MLBr_02671|M.leprae_Br4923 ITGNGKAPMLMLKGAPEKILPRCRFADPEADVAHAESLVRHLAEQGLRVL
.. : ***: :* *: :. ***:*
MUL_0233|M.ulcerans_Agy99 LLGVAAVAVDDP-----------CAPGQVTPAALVILEQKVRPDARETME
MMAR_4622|M.marinum_M LLGVADVAVDDP-----------CAPGQVTPAALVILEQKVRPDARETME
Mb0932|M.bovis_AF2122/97 LLAAGSVAVDHA-----------QAPGQVTPVALVVLEQKVRPDARETLD
Rv0908|M.tuberculosis_H37Rv LLAAGSVAVDHA-----------QAPGQVTPVALVVLEQKVRPDARETLD
MAV_1031|M.avium_104 LLGAADRAVDHP-----------DAPGPITPVALVVLEQKVRPDARETLD
Mflv_1758|M.gilvum_PYR-GCK LLGSSDRPVDAP-----------DAPGVVTPAALVVLEQRVRPDARGTLD
MSMEG_5636|M.smegmatis_MC2_155 LLGSSDRSVDAP-----------DAPGVVTPAALVVLEQRIRPDAGDTLD
Mvan_4989|M.vanbaalenii_PYR-1 LLGSSDRSVDAP-----------DAPGTVTPSALVVLEQRIRPDARDTLD
TH_0097|M.thermoresistible__bu LLGSSDLPVDHP-----------QAPGAVTPVALVVLEQRIRSDARDTLE
MAB_0962|M.abscessus_ATCC_1997 LLASAELSVDDA-----------HAPGAVTPRALVVLEQKIRPDARETLD
MLBr_02671|M.leprae_Br4923 AVAQCSWGHDTTDDNDTDADAVDAAAHDLELVGYIGLADTARPSSRPLIE
:. * . *. : . : * : *..: ::
MUL_0233|M.ulcerans_Agy99 YFAAQNVSVKVISGDNAVSVGAVAAKLGLQGQTMDAR---QLPSEQPELA
MMAR_4622|M.marinum_M YFAAQNVSVKVISGDNAVSVGAVAAKLGLQVQTMDAR---QLPSEQPELA
Mb0932|M.bovis_AF2122/97 YFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDAR---ALPTGREELA
Rv0908|M.tuberculosis_H37Rv YFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDAR---ALPTGREELA
MAV_1031|M.avium_104 YFADQGVSVKVLSGDNAVSVGAVAGELGLHGETLDAR---QLPSDLAQLA
Mflv_1758|M.gilvum_PYR-GCK YFASQHVAIKVISGDNAVSVGAVAGSLGLQGETMDAR---RLPEQQDELA
MSMEG_5636|M.smegmatis_MC2_155 YFASQHVSVKVISGDNAVSVGAVAGKLGLHGETMDAR---RLPEQPEKLA
Mvan_4989|M.vanbaalenii_PYR-1 YFASQKVSVKVISGDNAVSVGAVAGSLGLGGETMDAR---RLPDQPDALA
TH_0097|M.thermoresistible__bu YFASQQVSIKVISGDNAASVGAVSESLGLEGEAIDAR---RLPEDPDELA
MAB_0962|M.abscessus_ATCC_1997 YFASQHVSIKVISGDNAVSVSAVAQTLGLTGAAVDAR---TLPTDTDKLA
MLBr_02671|M.leprae_Br4923 ALVTAGRNVVLITGDHPITARAIAQQLGLRSDARVVNGTELIGLDEDACA
:. : :::**:. :. *:: *** : .. : *
MUL_0233|M.ulcerans_Agy99 DVLDTYITFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
MMAR_4622|M.marinum_M DVLDTYTTFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
Mb0932|M.bovis_AF2122/97 DTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
Rv0908|M.tuberculosis_H37Rv DTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
MAV_1031|M.avium_104 DMLDTYTTFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
Mflv_1758|M.gilvum_PYR-GCK ETLEECTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDADIG
MSMEG_5636|M.smegmatis_MC2_155 ETLEECTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDSDIG
Mvan_4989|M.vanbaalenii_PYR-1 DTLEQCTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDADIG
TH_0097|M.thermoresistible__bu DTLQRYTTFGRVRPDQKRSMVHALQSRGHTVAMTGDGVNDVLALKDADIG
MAB_0962|M.abscessus_ATCC_1997 ATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGVNDVLALKDADIG
MLBr_02671|M.leprae_Br4923 ELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDGANDAAAIRMADVG
*.** *:** :* *** *:..**.***.**. *:: :*:*
MUL_0233|M.ulcerans_Agy99 VAMGT-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIRNIERVANLFLT
MMAR_4622|M.marinum_M VAMGT-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIGNIERVANLFLT
Mb0932|M.bovis_AF2122/97 VAMGS-GSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLT
Rv0908|M.tuberculosis_H37Rv VAMGS-GSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLT
MAV_1031|M.avium_104 VAMGA-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIGNIERVANLFLT
Mflv_1758|M.gilvum_PYR-GCK VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT
MSMEG_5636|M.smegmatis_MC2_155 VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT
Mvan_4989|M.vanbaalenii_PYR-1 VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT
TH_0097|M.thermoresistible__bu VAMGS-GSPATRAVAQIVLLDNKFATLPHVVAEGRRVIGNIERVSNLFLT
MAB_0962|M.abscessus_ATCC_1997 VAMGA-GSSASRAVAQIVLLDNKFATLPYVVAEGRRVIGNIERVSNLFLT
MLBr_02671|M.leprae_Br4923 IGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTILVG
:.:. **.*:*..*:*** :: :..* .: *** : .:. . .:::
MUL_0233|M.ulcerans_Agy99 KAVYSALLALLVGIECLFAKPLGADPLLYP------FQPIHVTIAAWFT-
MMAR_4622|M.marinum_M KTVYSALLALLVGIECLFAKPLGADPLLYP------FQPIHVTIAAWFT-
Mb0932|M.bovis_AF2122/97 KTVYSVLLALLVGIECLIAIPLRRDPLLFP------FQPIHVTIAAWFT-
Rv0908|M.tuberculosis_H37Rv KTVYSVLLALLVGIECLIAIPLRRDPLLFP------FQPIHVTIAAWFT-
MAV_1031|M.avium_104 KTVYSVLLALLVGLECLFAKALKADPLLYP------FQPIHVTVAAWFT-
Mflv_1758|M.gilvum_PYR-GCK KTVYSVLLAVLVGLAGLSAEIFDTDPLLFP------FQPIHVTIAAWFT-
MSMEG_5636|M.smegmatis_MC2_155 KTVYSVLLAILVGIGGLSAKIFGTDPLLFP------FQPIHVTIAAWFT-
Mvan_4989|M.vanbaalenii_PYR-1 KTVYSVLLAVLVGLGGLSAKLFGSDPLLFP------FQPIHVTIAAWFT-
TH_0097|M.thermoresistible__bu KTVYSVLLAVLVGLGGLASVFFEADPLLFP------FQPIHVTIAAWFT-
MAB_0962|M.abscessus_ATCC_1997 KTVYSVLLALTVGLAGLGSKIFHYGAVPFP------FQPIHVTIAAWFT-
MLBr_02671|M.leprae_Br4923 GNVGEVVFTIIGTVFGAGRAPVGTRQLLLVNLLTDMFPALSIAVTSQYEE
* ..:::: : . : * .: ::::: :
MUL_0233|M.ulcerans_Agy99 IGIPSFILSLAPNDER------AYPGFVRRVLTSALPSGLVVGVATFVSY
MMAR_4622|M.marinum_M IGIPSFILSLAPNDER------AYPGFVRRVLTSALPSGLVVGVATFVSY
Mb0932|M.bovis_AF2122/97 IGIPAFILSLAPNNER------AYPGFVRRVMTSAVPFGLVIGVATFVTY
Rv0908|M.tuberculosis_H37Rv IGIPAFILSLAPNNER------AYPGFVRRVMTSAVPFGLVIGVATFVTY
MAV_1031|M.avium_104 IGIPSFILSLAPNNER------AHPGFVRRVLSSALPSGLIVGAATFASY
Mflv_1758|M.gilvum_PYR-GCK IGIPAFVLSLAPNNER------AHPGFVRRVMTAALPSGVVVGIATFTSY
MSMEG_5636|M.smegmatis_MC2_155 IGIPAFILSLAPNNER------AKTGFVRRVMTAALPSGLVVGTATFVSY
Mvan_4989|M.vanbaalenii_PYR-1 IGIPAFVLSLAPNNER------AHPGFVRRVMTSALPSGIVVGAATFTSY
TH_0097|M.thermoresistible__bu IGIPAFILSLAPNTER------AKPHFVRRVMTSALPSGITIGIATFTSY
MAB_0962|M.abscessus_ATCC_1997 IGIPAFILSLAPNNER------AQTGFVRRVMLSAIPSGLTVGIATFLSY
MLBr_02671|M.leprae_Br4923 PGEDEYQTDEEADEARRTHQHEVLTGPTPSLDAPLMRQIVNRGVVTAAGA
* : . .: * . . . : . : : * .*
MUL_0233|M.ulcerans_Agy99 LTAYPGRHSTWQEQTQASTAALITLLVTALWVLAVVARPYRWWRLGLVIA
MMAR_4622|M.marinum_M LTAYPGRHSTWQEQTQASTAALITLLVTALWVLAVVARPYRWWRLGLVIA
Mb0932|M.bovis_AF2122/97 LAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLA
Rv0908|M.tuberculosis_H37Rv LAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLA
MAV_1031|M.avium_104 LVAYHGRHATFQQQDQASTAALITLLVTALWVLAVVARPYQWWRVALVIA
Mflv_1758|M.gilvum_PYR-GCK LLAYQGRAATETEQTQASTAALITLLVAALWVLAVVARPYEWWRVALVSI
MSMEG_5636|M.smegmatis_MC2_155 LVAYQGREATPVEQTQASTAALITLLASSLWVLAVVARPYQWWRVLLVAC
Mvan_4989|M.vanbaalenii_PYR-1 LLAYQGRAATEAEQTQASTAALITLLVAGVWVLSVVARPYEWWRVALVAV
TH_0097|M.thermoresistible__bu LIAYQGREATAVQQTQASTAALITLLVAALWVLAVVARPYQWWRVALVLV
MAB_0962|M.abscessus_ATCC_1997 LLARQILHVSG-NSTQASTAALITELVAAVWVLAVVARPYQWWRVALVAL
MLBr_02671|M.leprae_Br4923 TTAWAIGRWTPGTERRTATMG-LTALVTTQLAQTLLTRRHSPLVVATALG
* : . :::* . :* * : . ::::* : : .
MUL_0233|M.ulcerans_Agy99 CGLAYVAIFSLPLAQRKFFLDPS-NLATTSIALGIGVLGAALIEAMWWLR
MMAR_4622|M.marinum_M CGLAYVAIFSLPLAQRKFFLDPS-NLATTSIALGIGLLGAALIEAMWWLR
Mb0932|M.bovis_AF2122/97 SGLAYVVIFSLPLAREKFLLDAS-NLATTSIALAVGVVGAATIEAMWWIR
Rv0908|M.tuberculosis_H37Rv SGLAYVVIFSLPLAREKFLLDAS-NLATTSIALAVGVVGAATIEAMWWIR
MAV_1031|M.avium_104 SGLAYVVIFSLPLARKAFLLDPS-NVVVTLSALGIGVLGAAAIEAAWWIR
Mflv_1758|M.gilvum_PYR-GCK SALAYVVIFSIPAARELFILDPT-NMTTTSTALAIGIAAAAAIEVLWWVQ
MSMEG_5636|M.smegmatis_MC2_155 SMLAYVLIFSIPLAQELFMLDPT-NMKVTSVALGIGLAGAALIEVLWWVQ
Mvan_4989|M.vanbaalenii_PYR-1 SGLAYVVIFSIPLARELFILDPS-NTALTSMALGIGLAAAVAIEVIWWVQ
TH_0097|M.thermoresistible__bu SMLAYVVIFAIPLARDVFMLDPS-NVAVTATAFGIGVIAAAVIEAAWWVQ
MAB_0962|M.abscessus_ATCC_1997 SGLGYVAIFAIPLARKAFMLDPG-NLAVTGPALGIGIAAAAVIEAVWWLQ
MLBr_02671|M.leprae_Br4923 SAGVLIGIIQTPVISQFFGCTPLGPIAWSGVITATAGATAVSVLAPQWLN
. : *: * * . : . . *. : . *:.
MUL_0233|M.ulcerans_Agy99 ARALGLRPRVWR----
MMAR_4622|M.marinum_M ARALGLRPRVWR----
Mb0932|M.bovis_AF2122/97 SRMLGVKPRVWR----
Rv0908|M.tuberculosis_H37Rv SRMLGVKPRVWR----
MAV_1031|M.avium_104 AKMLGVRPRVWR----
Mflv_1758|M.gilvum_PYR-GCK GHVLGERRRLWRAADG
MSMEG_5636|M.smegmatis_MC2_155 GRVLGEERRVWR----
Mvan_4989|M.vanbaalenii_PYR-1 GRVLGEHRRLWRVRER
TH_0097|M.thermoresistible__bu GRMLGETRRLWK----
MAB_0962|M.abscessus_ATCC_1997 GKWSGQPRHFWATGDD
MLBr_02671|M.leprae_Br4923 -KAFGIAQLNQE----
: *