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M. thermoresistible (build 8) TH_0006 (dinP)

annotation: POSSIBLE DNA-DAMAGE-INDUCIBLE PROTEIN P DINP (DNA POLYMERASE V) (POL IV 2) (DNA NUCLEOTIDYLTRANSFERASE (DNA-DIRECTED))
coordinates: 5978 - 7081
length: 368

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0006dinP-100% (368)POSSIBLE DNA-DAMAGE-INDUCIBLE PROTEIN P DINP (DNA POLYMERASE V) (POL IV 2) (DNA NUCLEOTIDYLTRANSFERASE (DNA-DIRECTED))
M. thermoresistible (build 8)TH_1151dinP3e-2640.74% (189) DNA polymerase IV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3082dinP1e-14471.95% (353) DNA polymerase IV
M. gilvum PYR-GCKMflv_4310-1e-15171.99% (357) DNA polymerase IV
M. tuberculosis H37RvRv3056dinP1e-14471.95% (353) DNA polymerase IV
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2702c-7e-4535.92% (348) DNA polymerase IV
M. marinum MMMAR_2359dinP_12e-4538.04% (347) DNA polymerase IV, DinP_1
M. avium 104MAV_3925-1e-14773.94% (353) DNA polymerase IV
M. smegmatis MC2 155MSMEG_2294dinB1e-15577.56% (352) DNA polymerase IV
M. ulcerans Agy99MUL_1535dinP_12e-4538.04% (347) DNA polymerase IV
M. vanbaalenii PYR-1Mvan_2037-1e-15173.52% (355) DNA polymerase IV

CLUSTAL 2.0.9 multiple sequence alignment


Mb3082|M.bovis_AF2122/97            ----MPTAAPRWILHVDLDQFLASVELLRHPELAGLPVIVGGNGDPTEPR
Rv3056|M.tuberculosis_H37Rv         ----MPTAAPRWILHVDLDQFLASVELLRHPELAGLPVIVGGNGDPTEPR
MAV_3925|M.avium_104                ------------MLHVDLDQFLASVELRRRPELAGLPVIVGGNGDPNEPR
Mflv_4310|M.gilvum_PYR-GCK          MSDPPAAGERDWVLHVDMDQFLASVELQRRPDLVGLPVIVGGNGDPAEPR
Mvan_2037|M.vanbaalenii_PYR-1       MTTPGTGPGKEWILHVDMDQFLASVELQRHPELVGHPVIVGGSGDPTEPR
MSMEG_2294|M.smegmatis_MC2_155      MT--------KWVLHVDLDQFLASVELRRRPDLRGQPVIVGGSGDPSEPR
TH_0006|M.thermoresistible__bu      ------VPAMTWVLHVDLDQFLAAVELRRRPELAGTPVIVGGSGDPTEPR
MMAR_2359|M.marinum_M               -------MESRWVLHLDMDAFFASVEQLTRPTLMGRPVLVGGMGG----R
MUL_1535|M.ulcerans_Agy99           ----MPVVESRWVLHLDMDAFFASVEQLTRPTLMGRPVLVGGMGG----R
MAB_2702c|M.abscessus_ATCC_199      -----MCAAGRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGTGG----R
                                                :**:*:* *:*:**   :* * * **:*** *.    *

Mb3082|M.bovis_AF2122/97            KVVTCASYEARAYGVRAGMPLRTAARRCP---EATFLPSNPAAYNAASEE
Rv3056|M.tuberculosis_H37Rv         KVVTCASYEARAYGVRAGMPLRTAARRCP---EATFLPSNPAAYNAASEE
MAV_3925|M.avium_104                KVVTCASYEAREFGVRAGMPLRAAARRCPPDSGVTFLPSDPAAYDAASDQ
Mflv_4310|M.gilvum_PYR-GCK          KVVTCASYEARTFGVHAGMPLRAAARRCP---DATFLPSDPEAYDAASDR
Mvan_2037|M.vanbaalenii_PYR-1       KVVTCASYEARQFGVHAGMPLRSAARRCP---DATFLPSDPEAYDAASER
MSMEG_2294|M.smegmatis_MC2_155      KVVTCASYEAREFGVHAGMPLRAAARRCP---DATFLPSDPAAYDEASEQ
TH_0006|M.thermoresistible__bu      KVVTCASYEARRFGVHAGMPLRTAARKCP---DATFLPSDPQAYDAASEQ
MMAR_2359|M.marinum_M               GVVAGASYEARVFGARSAMPMHQARRLIG--VTAVVLPPRGAVYGVASRR
MUL_1535|M.ulcerans_Agy99           GVVAGASYEARVFGARSAMPMHQARRLIG--VTAVVLPPRGAVYGVASRR
MAB_2702c|M.abscessus_ATCC_199      GVVAGASYEARVFGARSAMPMHQARRLVG--INAVVLPPRGSVYGVASRR
                                     **: ****** :*.::.**:: * *       ...**.   .*. ** .

Mb3082|M.bovis_AF2122/97            VVALLRDLGYPVEVWGWDEAYLAVAPGT----------PDDPIEVAEEIR
Rv3056|M.tuberculosis_H37Rv         VVALLRDLGYPVEVWGWDEAYLAVAPGT----------PDDPIEVAEEIR
MAV_3925|M.avium_104                VMGLLRDLGHPVEVWGWDEAYLAVT-------------ATDPIEVAEQIR
Mflv_4310|M.gilvum_PYR-GCK          VMGILRDLGHPVEVWGWDEAYVGARV-------------SDPFALARHIQ
Mvan_2037|M.vanbaalenii_PYR-1       VMGLLRDLGHPIEVWGWDEAYVGARV-------------ADPLALAHRIQ
MSMEG_2294|M.smegmatis_MC2_155      VMGLLRDLGHPLEVWGWDEAYLGADLPDE----------SDPVEVAERIR
TH_0006|M.thermoresistible__bu      VMDLLRDFGHPVEVLGWDEAFIGIGGGGTGEGVGGSAAATDPVALAEDIR
MMAR_2359|M.marinum_M               VFDTVRGLVPVVEQLSFDEAFGEPPQLGG-------AATAEVEQFCEDLR
MUL_1535|M.ulcerans_Agy99           VFDTVRGLVPVVEQLSFDEAFGEPPQLGG-------AATAEVEQFCEDLR
MAB_2702c|M.abscessus_ATCC_199      VFETVRSMIPILEQLSFDEAFGEPSELFG-------ATTSAVADYIHELR
                                    *.  :*.:   :*  .:***:                         . ::

Mb3082|M.bovis_AF2122/97            KVILSQTGLSCSIGISDNKQRAKIATGLAKPAGIYQLTDANWMAIMGDRT
Rv3056|M.tuberculosis_H37Rv         KVILSQTGLSCSIGISDNKQRAKIATGLAKPAGIYQLTDANWMAIMGDRT
MAV_3925|M.avium_104                GVISSETGLSCSVGISDNKQRAKIATGFAKPDGVFVLTDANWMALMADRP
Mflv_4310|M.gilvum_PYR-GCK          TVVASQTGLTCSVGISDNKQRAKVATGFGKPAGVHMLTDENWMPVMGDRP
Mvan_2037|M.vanbaalenii_PYR-1       HVVAAETGLSCSVGISDNKQRAKVATGFGKPAGVHALTDDNWMLTMGDRP
MSMEG_2294|M.smegmatis_MC2_155      TVVAAETGLSCSVGISDNKQRAKVATGFAKPAGIYVLTEANWMTVMGDRP
TH_0006|M.thermoresistible__bu      AAVTAETGLSCSIGISDNKQRAKVATGFAKPAGIYRLTDANWMAVMGDRP
MMAR_2359|M.marinum_M               RRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVARQEEQLLLGGLP
MUL_1535|M.ulcerans_Agy99           RRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVARKEEQLLLGGLP
MAB_2702c|M.abscessus_ATCC_199      SRVLGETGLTASVGAGSGKQIAKIASGLAKPDGVRIIAPEEERTLLDELP
                                      :  :*** .*:* ...** **:*:*:.** *:  ::  :    :   .

Mb3082|M.bovis_AF2122/97            VEALWGVGPKTTKRLAKLGINTVYQLAHTDSGLLMSTFGPRTALWLLL-A
Rv3056|M.tuberculosis_H37Rv         VEALWGVGPKTTKRLAKLGINTVYQLAHTDSGLLMSTFGPRTALWLLL-A
MAV_3925|M.avium_104                VDALWGVGPKTAKKLADLQITTVWQLAHSDAELLTATFGPRTGLWLLLLA
Mflv_4310|M.gilvum_PYR-GCK          VDALWGVGPKTAKKLAAIGITTVADLAGTDSAELTKTFGPTTGLWILLLA
Mvan_2037|M.vanbaalenii_PYR-1       VDALWGVGPKTAKKLAAMGITTVADLAGTDAAVLTTAFGPTTGLWILLLA
MSMEG_2294|M.smegmatis_MC2_155      PDALWGVGPKTTKKLAAMGITTVADLAVTDPSVLTTAFGPSTGLWLLLLA
TH_0006|M.thermoresistible__bu      VDALWGVGPKTAKRLATLGITTVADLEATDATVLTTTFGPSTGLWLLLLA
MMAR_2359|M.marinum_M               VRRLWGIGPVAEEKLHRLGIETVGQLAALADAEVANILGATVGPALHRLA
MUL_1535|M.ulcerans_Agy99           VRRLWGIGPVAEEKLHRLGIETVGQLAALADAEVANILGATVGPALHRLA
MAB_2702c|M.abscessus_ATCC_199      VRKLWGIGPVAEERLNRLGINTIGQFAALQTSEAASVLGGTIGPALHQLA
                                       ***:** : ::*  : * *: ::           :*   .  :   *

Mb3082|M.bovis_AF2122/97            KGGGDTEVSAQAWVPRSRSHAVTFPRDLTCRSEMESAVTELAQRTLNEVV
Rv3056|M.tuberculosis_H37Rv         KGGGDTEVSAQAWVPRSRSHAVTFPRDLTCRSEMESAVTELAQRTLNEVV
MAV_3925|M.avium_104                KGGGDDHVSAQPWVPRSRSHVVTFPRDLTDRAEMETAVTDLADQAVAEVL
Mflv_4310|M.gilvum_PYR-GCK          KGGGDTTVSAEPWVPRSRSHVITFPQDLTERAAMDEAVTELARRTLDEVI
Mvan_2037|M.vanbaalenii_PYR-1       KGGGDTKVSAEPWVPRSRSHVVTFPQDLTDRSEMARAVADLAQYTLAEVT
MSMEG_2294|M.smegmatis_MC2_155      KGGGDTEVSSEPWVPRSRSHVVTFPQDLTERREMDSAVRDLALQTLAEIV
TH_0006|M.thermoresistible__bu      KGGGDTEVSAEPWVPRSRSHVVTFPRDLTERAEMDAAVADLARRTVDEVV
MMAR_2359|M.marinum_M               RGIDDRPVAER-AEAKQISAESTFAIDLTTLDQLRDALDPIAEHAHQRLL
MUL_1535|M.ulcerans_Agy99           RGIDDRPVAER-AEAKQISAESTFAIDLTTLDQLRDALDPIAEHAHQRLL
MAB_2702c|M.abscessus_ATCC_199      RGVDDRPVAER-AETKQISAESTFPDDLTTLDQLRQAIEPIGVHAHRRLI
                                    :* .*  *: .   .:. *   **. ***    :  *:  :.  :  .: 

Mb3082|M.bovis_AF2122/97            ASSRTVTRVAVTVRTATFYTRTKIRKLQAPSTDPDVITAAARHVLDLFEL
Rv3056|M.tuberculosis_H37Rv         ASSRTVTRVAVTVRTATFYTRTKIRKLQAPSTDPDVITAAARHVLDLFEL
MAV_3925|M.avium_104                AAGRVVTRVAVTVRTATFYTRTKIRKLDAPSTDRDVIVAAALRVLDLFEL
Mflv_4310|M.gilvum_PYR-GCK          AQQRIVTHVAVTLRTSSFHTRSKIRKLPEPTIDADAVISTATTLLDAFDL
Mvan_2037|M.vanbaalenii_PYR-1       EQQRVVTRVAVTVRTSTFYTRTKIRKLSSPTTDSDPVVGTALDLLGQFDL
MSMEG_2294|M.smegmatis_MC2_155      EQGRIVTRVAVTVRTSTFYTRTKIRKLPAPSTDAGQIVDTALAVLDQFEL
TH_0006|M.thermoresistible__bu      AAGRIVTRVAVTVRTDTFSTRTKIRKLPVPSTDPDLITATALAVMDLFDI
MMAR_2359|M.marinum_M               RDGRGSRTVTVKLKKADMSTLTRSATLPYATTDVGALLALARRLLLDPVQ
MUL_1535|M.ulcerans_Agy99           RDGRGSRTVTVKLKKADMSTLTRSATLPYATTDVGALLALARRLLLDPAQ
MAB_2702c|M.abscessus_ATCC_199      KHGRGVRTVTVKLRRSDMSILTRSATLPYATTERAVLMSAARRLLLDPVE
                                       *    *:*.::   :   ::  .*  .: :   :   *  ::     

Mb3082|M.bovis_AF2122/97            DRPVRLLGVRLELA------------------------------------
Rv3056|M.tuberculosis_H37Rv         DRPVRLLGVRLELA------------------------------------
MAV_3925|M.avium_104                DRPVRLLGVRLELVMPD---------------------------------
Mflv_4310|M.gilvum_PYR-GCK          QRPVRLLGVRLELAMPSATAARG---------------------------
Mvan_2037|M.vanbaalenii_PYR-1       DRPVRLLGVRLELVMPDSER------------------------------
MSMEG_2294|M.smegmatis_MC2_155      DRPVRLLGVRLELAMDDVPRPAVTAGT-----------------------
TH_0006|M.thermoresistible__bu      ERPVRLLGVRLELAMESGAQAGQAGR------------------------
MMAR_2359|M.marinum_M               IGPIRLLGVGFSGLSEVRQESLFPDLDLAAETSEEAHQDFHPSHGALSST
MUL_1535|M.ulcerans_Agy99           IGPIRLLGVGFSGLSELRQESLFPDLDLAAETSEEAHKDFHPSHGALSST
MAB_2702c|M.abscessus_ATCC_199      IGPIRLVGVGFSGFSDVQQTSLFPDLDQAEPVAES---DEVPSTAEPTHS
                                      *:**:** :.                                      

Mb3082|M.bovis_AF2122/97            --------------------------------------------------
Rv3056|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3925|M.avium_104                --------------------------------------------------
Mflv_4310|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2037|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2294|M.smegmatis_MC2_155      --------------------------------------------------
TH_0006|M.thermoresistible__bu      --------------------------------------------------
MMAR_2359|M.marinum_M               PAGAVWRIGDDVTHRELGHGWVQGAGHGVVTVRFETRGSGPGPARTFPIE
MUL_1535|M.ulcerans_Agy99           PAGAVWRIGDDVTHRELGHGWVQGAGHGVVTVRFETRDSGPGPARTFPIE
MAB_2702c|M.abscessus_ATCC_199      TAG--WGVGDDVDHAEFGHGWIQGTGHGVMTVRFETRSSGPGIARTFAVD
                                                                                      

Mb3082|M.bovis_AF2122/97            -----------------------------------------
Rv3056|M.tuberculosis_H37Rv         -----------------------------------------
MAV_3925|M.avium_104                -----------------------------------------
Mflv_4310|M.gilvum_PYR-GCK          -----------------------------------------
Mvan_2037|M.vanbaalenii_PYR-1       -----------------------------------------
MSMEG_2294|M.smegmatis_MC2_155      -----------------------------------------
TH_0006|M.thermoresistible__bu      -----------------------------------------
MMAR_2359|M.marinum_M               TSDITAANPVDSLDWPDFVGQLRVENAADTSTPAVDDLDDG
MUL_1535|M.ulcerans_Agy99           TSDITAANPVDSLDWPDFVGQLRVENAADTSTPAVDDLDDG
MAB_2702c|M.abscessus_ATCC_199      DPGIARADPVASLDWPGESAEP-VDDGDEIGTGG-------