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M. tuberculosis H37Rv Rv3821 (-)

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 4285973 - 4286686
length: 237

MWSTVLVLALSVICEPVRIGLVVLMLNRRRPLLHLLTFLCGGYTMAGGVAMVTLVVLGATPLAGHFSVAE
VQIGTGLIALLIAFALTTNVIGKHVRRATHARVGDDGGRVLRESVPPSGAHKLAVRARCFLQGDSLYVAG
VSGLGAALPSANYMGAMAAILASGATPATQALAVVTFNVVAFTVAEVPLVSYLAAPRKTRAFMAALQSWL
RSRSRRDAALLVAAGGCLMLTLGLSNL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3821--100% (237)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. tuberculosis H37RvRv1517-4e-3133.07% (254) hypothetical protein Rv1517

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3851-1e-12899.16% (237) integral membrane protein
M. gilvum PYR-GCKMflv_0400-2e-4341.35% (237) hypothetical protein Mflv_0400
M. leprae Br4923MLBr_01233-6e-4844.96% (238) hypothetical protein MLBr_01233
M. abscessus ATCC 19977MAB_3146c-7e-4844.68% (235) hypothetical protein MAB_3146c
M. marinum MMMAR_2352-8e-3334.01% (247) hypothetical protein MMAR_2352
M. avium 104MAV_1758-5e-4744.96% (238) hypothetical protein MAV_1758
M. smegmatis MC2 155MSMEG_0413-6e-4743.93% (239) hypothetical protein MSMEG_0413
M. thermoresistible (build 8)TH_4435-2e-2936.25% (251) PUTATIVE putative conserved hypothetical transmembrane protein
M. ulcerans Agy99MUL_1527-5e-3233.20% (247) hypothetical protein MUL_1527
M. vanbaalenii PYR-1Mvan_0277-6e-4943.04% (237) hypothetical protein Mvan_0277

CLUSTAL 2.0.9 multiple sequence alignment


Rv3821|M.tuberculosis_H37Rv         ----MWSTVLVLALSVICEPVRIGLVVLMLNRRRPLLHLLTFLCGGYTMA
Mb3851|M.bovis_AF2122/97            ----MWSTVLVLALSVICEPVRIGLVVLMLNRRRPLLHLLTFLCGGYTMA
MAB_3146c|M.abscessus_ATCC_199      ----MWTIVLLMAIGVSVEPTRLGLTVLMLNRPRPLLQLFVFLCGAFAMG
MSMEG_0413|M.smegmatis_MC2_155      ----MWIPLLLMAAVISLEPFRIGMTVVMINRPQPALQLSTFLAGGFLMG
Mvan_0277|M.vanbaalenii_PYR-1       ----MWFPLLVMAAAVSLEPFRIGMTVVMVNRPRPVLQLLSFLAGGFVMG
Mflv_0400|M.gilvum_PYR-GCK          ----MWITLLAMAVAVSLEPFRIGMTVLMINRPRPGLQLLAFLTGGFAMG
MLBr_01233|M.leprae_Br4923          ----MWITILLMAIAISLEPFRIGMTVLMLNRPRPTLQLLVFLCSGFTMG
MAV_1758|M.avium_104                ----MLITVLVMAAAVSVEPFRIGMAVLMMTRPRPVLQLLAFLAGGFAMG
MMAR_2352|M.marinum_M               ----MWTTVLILAVMTATEPVRLGVAIFLVSKPRPMVNLLAFWFGGMATG
MUL_1527|M.ulcerans_Agy99           ----MWTTVLILAVMTATEPVRLGVAIFLVSKPRPMVNLLAFWFGGMATG
TH_4435|M.thermoresistible__bu      VFGTMWGAVVLFALMAMGEPLRIGAAVLLISRPRPMFNLFLFWLGGIVAT
                                        *   :: :*     ** *:* .:.::.: :* .:*  *  ..    

Rv3821|M.tuberculosis_H37Rv         GGVAMVTLVVLGA--------TPL-AGHFSVAEVQIGTGLIALLIAFALT
Mb3851|M.bovis_AF2122/97            GGVAMVTLVVLGA--------TPL-AGHFSVAEVQIGTGLIALLIAFALT
MAB_3146c|M.abscessus_ATCC_199      LSLGLTLLFVLRV--------SPVGKADVSGPYIQIGLGVLALLVAAVLA
MSMEG_0413|M.smegmatis_MC2_155      TAVGMVVLFVMR---------PALGSAHFTLPRVQIAVGALILANAVLVA
Mvan_0277|M.vanbaalenii_PYR-1       TAVGLIVLFVLR---------PALGSAHFTLPRVQLGVGAVVLVNAVLLA
Mflv_0400|M.gilvum_PYR-GCK          TAVGVAVLFLLR---------PVLDSAQFTLPRVQIVVGLVVLCTAAAVG
MLBr_01233|M.leprae_Br4923          MTVGFVVLFVFRR--------RLMASMQLTLPKVQILIGVLALLVAAVLT
MAV_1758|M.avium_104                MTVGLVVLFLLRR--------VLLGSSYFTVPKVQLLIGVLALLVAAALA
MMAR_2352|M.marinum_M               IGVALAVLLLLGDLANAIVDNVSSLAATSVVGHLQVGLGVVALLVAALVA
MUL_1527|M.ulcerans_Agy99           IGVALAVLLLLGDLANAIVDNVSSLAATSVVGHLQVGLGVVALLVAALVA
TH_4435|M.thermoresistible__bu      VLAGVVVLFLLRDVIGVVTAAAAASGSAIDIMSIQIAVGALALALAPVIL
                                       ..  *.::                      :*:  * : *  *  : 

Rv3821|M.tuberculosis_H37Rv         TNVIGKHVRRATHARVGDDGGRVLRESVPPSGAHKLAVRA----RCFLQG
Mb3851|M.bovis_AF2122/97            TNVIGKHVRRATHARVGDNGGRVLRESVPPSGTHKLAVRA----RCFLQG
MAB_3146c|M.abscessus_ATCC_199      VTASGSRPPAAPRTTTGFAG--------------KLATRV----RGFLQN
MSMEG_0413|M.smegmatis_MC2_155      TGLLGGRRKDPGPPGRVRRM------------LGPAADRT----RTLLTG
Mvan_0277|M.vanbaalenii_PYR-1       TGVLGGNR-DGTAAGR----------------WAPLVTRA----RRLLEG
Mflv_0400|M.gilvum_PYR-GCK          SGLVGRPRDPGRAPGV-------------------LAMRA----RRLLDG
MLBr_01233|M.leprae_Br4923          VQVCISSEPPAESPVDSASG------------PPKPSKWAPRPLARLLNG
MAV_1758|M.avium_104                VDV----------PRRLGS---------------RPAAMA-RPAQRLLNG
MMAR_2352|M.marinum_M               TGFSVRSPALVASG-----AGDSS--TLMVAETPTRFSRLMASAQGALEG
MUL_1527|M.ulcerans_Agy99           TGFSVRSPALVASG-----AGDSS--TLMVAETPTRFSRLMASAQGALEG
TH_4435|M.thermoresistible__bu      LRSAARRKAAAPVGGPDWPTGRGP--SVDSSDAPSAFSRLSARVQGVLQG
                                                                                   * .

Rv3821|M.tuberculosis_H37Rv         DSLYVAGVSGLGAA-LPSANYMGAMAAILASGATPATQALAVVTFNVVAF
Mb3851|M.bovis_AF2122/97            DSLYVAGVSGLGAA-LPSANYMGAMAAILASGATPATQALAVVTFNVVAF
MAB_3146c|M.abscessus_ATCC_199      NSLWVAGVSGLGIA-LPSADFLAVIALIHASGETQPVQSMALLFFNVVAF
MSMEG_0413|M.smegmatis_MC2_155      SSLWAAGVAGLGIA-LPSVDYLAALALIVASGAAASTQFGALMLFNVVAF
Mvan_0277|M.vanbaalenii_PYR-1       RSLWTAGVAGLGIA-LPSIDYLAALALIVASGAAAAVQFSALIVFNVVAF
Mflv_0400|M.gilvum_PYR-GCK          RSLWTAAAVGLGTA-LPSVDYLAALALIAASGAAAATQFGALMAFNAVAF
MLBr_01233|M.leprae_Br4923          DSLWVAGVAGLGIA-LPSVDYLAALAVILTSGAAATTQVGALLMFNVVAF
MAV_1758|M.avium_104                DSLSVAGLAGLGIA-LPSVDYLAALAVIVASGAAAATQVGALLLFNVVAF
MMAR_2352|M.marinum_M               GFPWAAFVVGLSSAGPPPVEYLVALTAIGASGAAMGTQLSATFVYLLVML
MUL_1527|M.ulcerans_Agy99           GFPWAAFVVGLSSAGPPPVEYLVALTAIGVSGAAMGTQLSATFVYLLVML
TH_4435|M.thermoresistible__bu      GSPWVAFFIGAWLGPGPPVELVAALTAIVASGATAGTQVGAVVVFALVMF
                                        .*   *   .  *. : : .:: * .** :  .*  * . :  * :

Rv3821|M.tuberculosis_H37Rv         TVAEVPLVSYLAAPRKTRAFMAALQSWLRSRSRRDAALLVAAGGCLMLTL
Mb3851|M.bovis_AF2122/97            TVAEVPLVSYLAAPRKTRAFMAALQSWLRSRSRRDAALLVAAGGCLMLTL
MAB_3146c|M.abscessus_ATCC_199      SMVGLPLLSYAAMPGRTYQMVSALHTWVRSRRRIDVAGIVAVLGLILLTL
MSMEG_0413|M.smegmatis_MC2_155      ALVEIPLVCYLVAPERTRATLAAVYDWLKARGRRGFATLLAVVGCMLLGV
Mvan_0277|M.vanbaalenii_PYR-1       ALVEIPLLCYLVAPDRTRAALSSLYEWVRAQGRRGVSLLLAVVGCVLVAV
Mflv_0400|M.gilvum_PYR-GCK          ALIEIPLLCYLVSPDRTRAVLASLNSWIRARGRVGVCALMAIVGGVLLVV
MLBr_01233|M.leprae_Br4923          ALIEIPLAAYLLAPDTTRAWTAALNNWIRSRRRLEVATLLAGVSCLLLAV
MAV_1758|M.avium_104                ALVEIPLLAYLVAPARTAASMTALHNWIRSRRRPQVAVLLAAAGCVFLTV
MMAR_2352|M.marinum_M               AIIEIPLISYLVHPGRTEATMLWLRNWLRAHRRQIIAVAVGLAGIALVTN
MUL_1527|M.ulcerans_Agy99           AIIEIPLIGYLVHPGRTEATMLWLRNWLRAHRRQIIAVAVGLAGIALVTN
TH_4435|M.thermoresistible__bu      AFAEIPLISHLVAPTRTEAVMMRLHTWVRVHRGRVFAVGLAVLGGYLLGT
                                    :.  :**  :   *  *      :  *:: :     .  :.  .  ::  

Rv3821|M.tuberculosis_H37Rv         GLSNL---
Mb3851|M.bovis_AF2122/97            GLSNL---
MAB_3146c|M.abscessus_ATCC_199      GIFGILRA
MSMEG_0413|M.smegmatis_MC2_155      GIAAL---
Mvan_0277|M.vanbaalenii_PYR-1       GFAGL---
Mflv_0400|M.gilvum_PYR-GCK          GLAGL---
MLBr_01233|M.leprae_Br4923          GIAGL---
MAV_1758|M.avium_104                GVTGL---
MMAR_2352|M.marinum_M               GMGTI---
MUL_1527|M.ulcerans_Agy99           GMGTI---
TH_4435|M.thermoresistible__bu      GLTG----
                                    *.