For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
WFPLLVMAAAVSLEPFRIGMTVVMVNRPRPVLQLLSFLAGGFVMGTAVGLIVLFVLRPALGSAHFTLPRV QLGVGAVVLVNAVLLATGVLGGNRDGTAAGRWAPLVTRARRLLEGRSLWTAGVAGLGIALPSIDYLAALA LIVASGAAAAVQFSALIVFNVVAFALVEIPLLCYLVAPDRTRAALSSLYEWVRAQGRRGVSLLLAVVGCV LVAVGFAGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0277 | - | - | 100% (220) | hypothetical protein Mvan_0277 |
| M. vanbaalenii PYR-1 | Mvan_0642 | - | 3e-08 | 25.32% (233) | hypothetical protein Mvan_0642 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3851 | - | 2e-49 | 42.62% (237) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0400 | - | 3e-79 | 69.23% (221) | hypothetical protein Mflv_0400 |
| M. tuberculosis H37Rv | Rv3821 | - | 4e-49 | 43.04% (237) | integral membrane protein |
| M. leprae Br4923 | MLBr_01233 | - | 4e-62 | 55.60% (232) | hypothetical protein MLBr_01233 |
| M. abscessus ATCC 19977 | MAB_0934 | - | 1e-67 | 58.37% (221) | hypothetical protein MAB_0934 |
| M. marinum M | MMAR_2352 | - | 9e-33 | 35.83% (240) | hypothetical protein MMAR_2352 |
| M. avium 104 | MAV_1758 | - | 1e-65 | 60.63% (221) | hypothetical protein MAV_1758 |
| M. smegmatis MC2 155 | MSMEG_0413 | - | 5e-88 | 70.67% (225) | hypothetical protein MSMEG_0413 |
| M. thermoresistible (build 8) | TH_4435 | - | 2e-31 | 34.27% (248) | PUTATIVE putative conserved hypothetical transmembrane protein |
| M. ulcerans Agy99 | MUL_1527 | - | 3e-32 | 35.42% (240) | hypothetical protein MUL_1527 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3851|M.bovis_AF2122/97 ----MWSTVLVLALSVICEPVRIGLVVLMLNRRRPLLHLLTFLCGGYTMA
Rv3821|M.tuberculosis_H37Rv ----MWSTVLVLALSVICEPVRIGLVVLMLNRRRPLLHLLTFLCGGYTMA
Mvan_0277|M.vanbaalenii_PYR-1 ----MWFPLLVMAAAVSLEPFRIGMTVVMVNRPRPVLQLLSFLAGGFVMG
MSMEG_0413|M.smegmatis_MC2_155 ----MWIPLLLMAAVISLEPFRIGMTVVMINRPQPALQLSTFLAGGFLMG
Mflv_0400|M.gilvum_PYR-GCK ----MWITLLAMAVAVSLEPFRIGMTVLMINRPRPGLQLLAFLTGGFAMG
MLBr_01233|M.leprae_Br4923 ----MWITILLMAIAISLEPFRIGMTVLMLNRPRPTLQLLVFLCSGFTMG
MAV_1758|M.avium_104 ----MLITVLVMAAAVSVEPFRIGMAVLMMTRPRPVLQLLAFLAGGFAMG
MAB_0934|M.abscessus_ATCC_1997 ----MWITLLVMAIAVSFEPFRLGMTVLMLNRPRPMLQLLAFLSGGFVMG
MMAR_2352|M.marinum_M ----MWTTVLILAVMTATEPVRLGVAIFLVSKPRPMVNLLAFWFGGMATG
MUL_1527|M.ulcerans_Agy99 ----MWTTVLILAVMTATEPVRLGVAIFLVSKPRPMVNLLAFWFGGMATG
TH_4435|M.thermoresistible__bu VFGTMWGAVVLFALMAMGEPLRIGAAVLLISRPRPMFNLFLFWLGGIVAT
* .:: :* **.*:* .:.::.: :* .:* * .*
Mb3851|M.bovis_AF2122/97 GGVAMVTLVVLGA--------TPLAG-HFSVAEVQIGTGLIALLIAFALT
Rv3821|M.tuberculosis_H37Rv GGVAMVTLVVLGA--------TPLAG-HFSVAEVQIGTGLIALLIAFALT
Mvan_0277|M.vanbaalenii_PYR-1 TAVGLIVLFVLR---------PALGSAHFTLPRVQLGVGAVVLVNAVLLA
MSMEG_0413|M.smegmatis_MC2_155 TAVGMVVLFVMR---------PALGSAHFTLPRVQIAVGALILANAVLVA
Mflv_0400|M.gilvum_PYR-GCK TAVGVAVLFLLR---------PVLDSAQFTLPRVQIVVGLVVLCTAAAVG
MLBr_01233|M.leprae_Br4923 MTVGFVVLFVFRR--------RLMASMQLTLPKVQILIGVLALLVAAVLT
MAV_1758|M.avium_104 MTVGLVVLFLLRR--------VLLGSSYFTVPKVQLLIGVLALLVAAALA
MAB_0934|M.abscessus_ATCC_1997 MAVGLVVLFAFRN--------VSTGSAHFTLPRVQIGIGVAALLVAALVA
MMAR_2352|M.marinum_M IGVALAVLLLLGDLANAIVDNVSSLAATSVVGHLQVGLGVVALLVAALVA
MUL_1527|M.ulcerans_Agy99 IGVALAVLLLLGDLANAIVDNVSSLAATSVVGHLQVGLGVVALLVAALVA
TH_4435|M.thermoresistible__bu VLAGVVVLFLLRDVIGVVTAAAAASGSAIDIMSIQIAVGALALALAPVIL
... .*. : . : :*: * * * :
Mb3851|M.bovis_AF2122/97 TNVIGK--HVRRATHARVGDNGGRVLRESVPPSGTHKLAVRARCFLQGDS
Rv3821|M.tuberculosis_H37Rv TNVIGK--HVRRATHARVGDDGGRVLRESVPPSGAHKLAVRARCFLQGDS
Mvan_0277|M.vanbaalenii_PYR-1 TGVLG------GNR-DGTAAGR------------WAPLVTRARRLLEGRS
MSMEG_0413|M.smegmatis_MC2_155 TGLLG------GRRKDPGPPGRV--------RRMLGPAADRTRTLLTGSS
Mflv_0400|M.gilvum_PYR-GCK SGLVG------RPRDPGRAPGV---------------LAMRARRLLDGRS
MLBr_01233|M.leprae_Br4923 VQVCIS--SEPPAESPVDSASGP--------PKPSKWAPRPLARLLNGDS
MAV_1758|M.avium_104 VDV------------PRRLGS-----------RPAAMA-RPAQRLLNGDS
MAB_0934|M.abscessus_ATCC_1997 SRL-------------RGPAS----------HAQLDKVSARIQSIATGGS
MMAR_2352|M.marinum_M TGFSVRSPALVASG-----AGDSSTLMVAETPTRFSRLMASAQGALEGGF
MUL_1527|M.ulcerans_Agy99 TGFSVRSPALVASG-----AGDSSTLMVAETPTRFSRLMASAQGALEGGF
TH_4435|M.thermoresistible__bu LRSAARRKAAAPVGGPDWPTGRGPSVDSSDAPSAFSRLSARVQGVLQGGS
. *
Mb3851|M.bovis_AF2122/97 LYVAGVSGLGAA-LPSANYMGAMAAILASGATPATQALAVVTFNVVAFTV
Rv3821|M.tuberculosis_H37Rv LYVAGVSGLGAA-LPSANYMGAMAAILASGATPATQALAVVTFNVVAFTV
Mvan_0277|M.vanbaalenii_PYR-1 LWTAGVAGLGIA-LPSIDYLAALALIVASGAAAAVQFSALIVFNVVAFAL
MSMEG_0413|M.smegmatis_MC2_155 LWAAGVAGLGIA-LPSVDYLAALALIVASGAAASTQFGALMLFNVVAFAL
Mflv_0400|M.gilvum_PYR-GCK LWTAAAVGLGTA-LPSVDYLAALALIAASGAAAATQFGALMAFNAVAFAL
MLBr_01233|M.leprae_Br4923 LWVAGVAGLGIA-LPSVDYLAALAVILTSGAAATTQVGALLMFNVVAFAL
MAV_1758|M.avium_104 LSVAGLAGLGIA-LPSVDYLAALAVIVASGAAAATQVGALLLFNVVAFAL
MAB_0934|M.abscessus_ATCC_1997 LWVAGVAGLGIA-LPSVDFLAALAVIVASGSPPATQISALLMFNVIAFAL
MMAR_2352|M.marinum_M PWAAFVVGLSSAGPPPVEYLVALTAIGASGAAMGTQLSATFVYLLVMLAI
MUL_1527|M.ulcerans_Agy99 PWAAFVVGLSSAGPPPVEYLVALTAIGVSGAAMGTQLSATFVYLLVMLAI
TH_4435|M.thermoresistible__bu PWVAFFIGAWLGPGPPVELVAALTAIVASGATAGTQVGAVVVFALVMFAF
.* * . *. : : *:: * .**:. .* * . : : ::.
Mb3851|M.bovis_AF2122/97 AEVPLVSYLAAPRKTRAFMAALQSWLRSRSRRDAALLVAAGGCLMLTLGL
Rv3821|M.tuberculosis_H37Rv AEVPLVSYLAAPRKTRAFMAALQSWLRSRSRRDAALLVAAGGCLMLTLGL
Mvan_0277|M.vanbaalenii_PYR-1 VEIPLLCYLVAPDRTRAALSSLYEWVRAQGRRGVSLLLAVVGCVLVAVGF
MSMEG_0413|M.smegmatis_MC2_155 VEIPLVCYLVAPERTRATLAAVYDWLKARGRRGFATLLAVVGCMLLGVGI
Mflv_0400|M.gilvum_PYR-GCK IEIPLLCYLVSPDRTRAVLASLNSWIRARGRVGVCALMAIVGGVLLVVGL
MLBr_01233|M.leprae_Br4923 IEIPLAAYLLAPDTTRAWTAALNNWIRSRRRLEVATLLAGVSCLLLAVGI
MAV_1758|M.avium_104 VEIPLLAYLVAPARTAASMTALHNWIRSRRRPQVAVLLAAAGCVFLTVGV
MAB_0934|M.abscessus_ATCC_1997 VEIPFLAHAVAPERTAEAMARLNSWIQSNRRRNIALVLTAVGCVLLAVGL
MMAR_2352|M.marinum_M IEIPLISYLVHPGRTEATMLWLRNWLRAHRRQIIAVAVGLAGIALVTNGM
MUL_1527|M.ulcerans_Agy99 IEIPLIGYLVHPGRTEATMLWLRNWLRAHRRQIIAVAVGLAGIALVTNGM
TH_4435|M.thermoresistible__bu AEIPLISHLVAPTRTEAVMMRLHTWVRVHRGRVFAVGLAVLGGYLLGTGL
*:*: : * * : *:: . . : . :: *.
Mb3851|M.bovis_AF2122/97 SNL
Rv3821|M.tuberculosis_H37Rv SNL
Mvan_0277|M.vanbaalenii_PYR-1 AGL
MSMEG_0413|M.smegmatis_MC2_155 AAL
Mflv_0400|M.gilvum_PYR-GCK AGL
MLBr_01233|M.leprae_Br4923 AGL
MAV_1758|M.avium_104 TGL
MAB_0934|M.abscessus_ATCC_1997 AGI
MMAR_2352|M.marinum_M GTI
MUL_1527|M.ulcerans_Agy99 GTI
TH_4435|M.thermoresistible__bu TG-