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VAVQSALVDRPGMLATARGLSHFGEHCIGWLILALLGAIALPRRRREWLVAGAGAFVAHAIAVLIKRLVR RQRPDHPAIAVNVDTPSQLSFPSAHATSTTAAALLMGRATGLPLPVVLVPPMALSRILLGVHYPSDVAVG VALGATVGAIVDSVGGGRQRARKR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3807c | - | - | 100% (165) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
M. tuberculosis H37Rv | Rv0308 | - | 3e-05 | 27.78% (126) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3837c | - | 1e-89 | 100.00% (165) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_1161 | - | 4e-57 | 68.63% (153) | phosphoesterase, PA-phosphatase related |
M. leprae Br4923 | MLBr_00094 | - | 6e-58 | 72.85% (151) | hypothetical protein MLBr_00094 |
M. abscessus ATCC 19977 | MAB_0172 | - | 4e-56 | 68.39% (155) | phosphoesterase |
M. marinum M | MMAR_5371 | - | 7e-60 | 72.08% (154) | transmembrane protein |
M. avium 104 | MAV_0210 | - | 5e-57 | 73.91% (138) | PAP2 superfamily protein |
M. smegmatis MC2 155 | MSMEG_6402 | - | 2e-57 | 66.24% (157) | PAP2 superfamily protein |
M. thermoresistible (build 8) | TH_2991 | - | 4e-56 | 66.45% (155) | PUTATIVE phosphoesterase, PA-phosphatase related |
M. ulcerans Agy99 | MUL_4991 | - | 6e-59 | 71.43% (154) | transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_5648 | - | 3e-62 | 72.44% (156) | phosphoesterase, PA-phosphatase related |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6402|M.smegmatis_MC2_155 -------MSDAPRGEDAVLVAVQAALAGRPGVLTGARALSHFGEHSAGWV TH_2991|M.thermoresistible__bu ---MREQMAEPLGREEAALVTIQAALAGRPGVLAAARALSHFGEHSLGWL Mflv_1161|M.gilvum_PYR-GCK -------MADSPRGEDAVLVAVQSTLGARPGVLPVARAMSHFGEHSLGWL Mvan_5648|M.vanbaalenii_PYR-1 -------MADAPRGEDAVLVAVQRALADRPGVLAVARGLSHFGEHSLGWL MAB_0172|M.abscessus_ATCC_1997 MTGPLPGEVTAPQGETAVLVAVQSALGGRPGVLSTARGLSHFGEHSIGWV MAV_0210|M.avium_104 -------------------------------MLTVARALSHFGEHSIGWV Rv3807c|M.tuberculosis_H37Rv ------------------MVAVQSALVDRPGMLATARGLSHFGEHCIGWL Mb3837c|M.bovis_AF2122/97 ------------------MVAVQSALVDRPGMLATARGLSHFGEHCIGWL MMAR_5371|M.marinum_M -----MPEPAPPRGEAAAIVAVQSALADRPGVLGTARGLSHFGEHSVGWL MUL_4991|M.ulcerans_Agy99 -----MPEPAPPRGEAAAIVAVQSALADRPGVLGTARGLSHFGEHSVGWL MLBr_00094|M.leprae_Br4923 -----MPEDKAPTGELAAIAAVQSVLVDRPGVLPTARGMSHFGEHSIGWL :* **.:******. **: MSMEG_6402|M.smegmatis_MC2_155 ALAAAGALAQPA---KRRSWLAVGAGAFLAHAAAVVIKRVVRRERPSHPD TH_2991|M.thermoresistible__bu GLAGLGALTQPA---RRRSWLAVGVGAFAAHAAAVLIKRVVRRRRPEHEA Mflv_1161|M.gilvum_PYR-GCK ALAGIGALVSPR---QRSDYLAAGAGAFAAHAAAVVIKRVVRRTRPHHPA Mvan_5648|M.vanbaalenii_PYR-1 AVAALGAVLSPR---RRRDYVTAGAGALLAHAAAVVIKRVVRRQRPHHPA MAB_0172|M.abscessus_ATCC_1997 AAGLIGAAINRRDKPRRRSWLAAGAGAFGAHAASVIIKRLVRRRRPSHEA MAV_0210|M.avium_104 AAAALGALCSPR---RRADWLAAGAGAFVAHAAAVVVKRIVRRERPHHPA Rv3807c|M.tuberculosis_H37Rv ILALLGAIALPR---RRREWLVAGAGAFVAHAIAVLIKRLVRRQRPDHPA Mb3837c|M.bovis_AF2122/97 ILALLGAIALPR---RRREWLVAGAGAFVAHAIAVLIKRLVRRQRPDHPA MMAR_5371|M.marinum_M LVSALGALLFPS---RRREWVVAGAGTFVAHAAAVVIKRVVRRKRPHDPA MUL_4991|M.ulcerans_Agy99 LVSALGAMLFPS---RRREWVVAGAGTFVAHAAAVVIKRVVRRKRPHDPA MLBr_00094|M.leprae_Br4923 AISLLGAILVPC---RRRYWLVAGAGVFAAHVAAVLIKRMVRRIRPNHPA . ** :* ::..*.*.: **. :*::**:*** ** . MSMEG_6402|M.smegmatis_MC2_155 IAVNVGTPSRLSFPSAHATSTTAAAVLLAQTTGVP---APALLVPPMALS TH_2991|M.thermoresistible__bu IRVHVATPSRLSFPSAHATSTTAAALLLARTTGSV---LPLLLIPPMAVS Mflv_1161|M.gilvum_PYR-GCK IAVNVATPSRLSFPSAHATSTTAAALLLARPTGLP---LPALLIPPMALS Mvan_5648|M.vanbaalenii_PYR-1 IAVNVGTPSRLSFPSAHATSTTAAAVLLARPTGLP---LPALLVPPMALS MAB_0172|M.abscessus_ATCC_1997 VRVNVSTPSRLSFPSSHATSTAAAAVLFAPLTGLP---LPALLIPPMALS MAV_0210|M.avium_104 VVVNVGTPSRLSFPSAHATSTTAAAILLGRITGLP---LPAVLVPPMALS Rv3807c|M.tuberculosis_H37Rv IAVNVDTPSQLSFPSAHATSTTAAALLMGRATGLP---LPVVLVPPMALS Mb3837c|M.bovis_AF2122/97 IAVNVDTPSQLSFPSAHATSTTAAALLMGRATGLP---LPVVLVPPMALS MMAR_5371|M.marinum_M VTVNVGTPSKLSFPSAHATSTAAAAILLSRAAGVPEAAGAAVLVPPMALS MUL_4991|M.ulcerans_Agy99 VTVNVGTPSKLSFPSAHATSTAAAAILLSRAAGVSEAAGAAVLVPPMALS MLBr_00094|M.leprae_Br4923 VTVNVGTPSPLSFPSAHATSTAAAAILIGRASRLPKGIVAAVLVAPMALS : *:* *** *****:*****:***:*:. : . :*:.***:* MSMEG_6402|M.smegmatis_MC2_155 RLVLGVHYPTDVVTGVVVGALVGKAVGKAAGRISNS---VGAEGDR---- TH_2991|M.thermoresistible__bu RLVLGVHYPTDVLTGVAVGAATATAVDLVTRKEADG---L-SEADR---- Mflv_1161|M.gilvum_PYR-GCK RLVLGVHYPTDVLAGVVVGAAVAKAVERA----------LEGATT----- Mvan_5648|M.vanbaalenii_PYR-1 RLVLGVHYPSDVLAGVVVGAVVGKAVGRLGDTLADR---AEGVSSS---- MAB_0172|M.abscessus_ATCC_1997 RLVLGVHYPTDVAAGAALGALIGAAVRRADSRLALK---EEQR------- MAV_0210|M.avium_104 RMVLGVHYPSDVACGIALGAGVAAVARRAP---------QLARGDQ---- Rv3807c|M.tuberculosis_H37Rv RILLGVHYPSDVAVGVALGATVGAIVDSVGGGRQ------RARKR----- Mb3837c|M.bovis_AF2122/97 RILLGVHYPSDVAVGVALGATVGAIVDSVGGGRQ------RARKR----- MMAR_5371|M.marinum_M RILLGVHYPSDVAAGIAVGASVAAIAARLD-KVS-----TKGMSL----- MUL_4991|M.ulcerans_Agy99 RILLGVHYPSDVAAGIAVGASVAAIAARLD-KVS-----TKGMSL----- MLBr_00094|M.leprae_Br4923 RIVLGVHYPSDVAFGVVLGAAVAGTTARFDSRLSRRWTVQHGLSSGSAVK *::******:** * .:** . .