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MTRPQALLAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHDIGIKNPAWVRFWDGVSLILGPVV LRPLGLLAAMVALAKRKIRIALLLLACLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATAS VLALLTVLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYLYFLVCLCVFRPPSI FGAQRASHALSPPVEVSRQPEPEVDTAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0308 | - | - | 100% (238) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv3807c | - | 5e-05 | 27.78% (126) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0316 | - | 1e-136 | 100.00% (238) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0312 | - | 3e-46 | 44.44% (225) | phosphoesterase, PA-phosphatase related |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0200c | - | 1e-44 | 44.28% (201) | phosphoesterase, PA-phosphatase related protein |
| M. marinum M | MMAR_0558 | - | 6e-78 | 64.25% (207) | hypothetical protein MMAR_0558 |
| M. avium 104 | MAV_4854 | - | 1e-60 | 53.37% (208) | PAP2 superfamily protein |
| M. smegmatis MC2 155 | MSMEG_0634 | - | 1e-46 | 47.00% (200) | PAP2 superfamily protein |
| M. thermoresistible (build 8) | TH_3242 | - | 1e-42 | 44.79% (192) | PUTATIVE putative phosphoesterase, PA-phosphatase related |
| M. ulcerans Agy99 | MUL_1222 | - | 4e-78 | 64.25% (207) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0429 | - | 3e-48 | 47.47% (198) | phosphoesterase, PA-phosphatase related |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0312|M.gilvum_PYR-GCK MTPDNRR----LLAGVVAALAVYGLLWAGWAQDWGWLTRADDAALDAAHR
MAB_0200c|M.abscessus_ATCC_199 MPARSDRGYVWPLLSAAAALIVFALLWLGYAQQWNGLSRLDVGALTPAHH
Mvan_0429|M.vanbaalenii_PYR-1 MRS------GWLIGSAAAALGVYLLMWVGYVQGWVWLAGIDADVLNPANR
MSMEG_0634|M.smegmatis_MC2_155 MERTRG----LLIASALVAVAVYALMWIGYRSGWPWLVSFDDAGLDPAFR
TH_3242|M.thermoresistible__bu VNRRTVG----LIGSAVAAVVVYGLLWFATAHGWDRLARLDAAALSAAHD
Rv0308|M.tuberculosis_H37Rv MTRPQAL---LAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHD
Mb0316|M.bovis_AF2122/97 MTRPQAL---LAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHD
MMAR_0558|M.marinum_M MTRPRMT---LPLLLALAAIVVYALMWIGYRQDWGWLHAMDWSLLNASHD
MUL_1222|M.ulcerans_Agy99 MTRPRMT---LPLLLALAAIVVYALMWIGYRQDWGWLHAMDWSLLNASHD
MAV_4854|M.avium_104 MMRPRPA---PAAAIALLATAVYAVMWIGYRHGWGWLARMDWSLLNGTRD
: . * *: ::* . * * * * :
Mflv_0312|M.gilvum_PYR-GCK VGESHSGWVTAWDVFCTVLGPGAFRLAVLVLIVLALLRRRIRLAVFL-VV
MAB_0200c|M.abscessus_ATCC_199 YGIAHPGWVTVWDVFATALGPGAFRIGGAIIIIVLLVRGQRRPAVFL-LV
Mvan_0429|M.vanbaalenii_PYR-1 FGDGRPRWVTAWDVLCTLLGPGAFRLAVLVVIVVALVRRRFRLAVFL-TV
MSMEG_0634|M.smegmatis_MC2_155 FGTEHPAWVTAWNVFCTVLGPYSFRAVFAVFIVVALIRRHFRPAVFA-LL
TH_3242|M.thermoresistible__bu FGADRPAWVMSWAVFCTVLGPMAFRLAALIAVVAAVRRRSPRVAVFL-LA
Rv0308|M.tuberculosis_H37Rv IGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLL-LA
Mb0316|M.bovis_AF2122/97 IGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLL-LA
MMAR_0558|M.marinum_M IGVKHPGWVNFWFAVSFVLGPITTRIVGLVAITIALVQRKMRMALLL-LA
MUL_1222|M.ulcerans_Agy99 IGVKHPGWVNFWFAVSFVLGPITTRIVGLVAITIALVQRKMRMALLL-LA
MAV_4854|M.avium_104 LAVKHPGWLRAAEVVSVVLGPGTLAVLGIAVTLCAVVLRRLRAALVLALA
. .. *: .. *** : * *:.
Mflv_0312|M.gilvum_PYR-GCK TVELSGLVTEIAKHLAGRARPDTAFVDAWGLSFPSGHALGVLVAVAALLS
MAB_0200c|M.abscessus_ATCC_199 TIELSALVTELAKLLAGRPRPATKLVDAYGTSFPSGHALGIMVCVLALLT
Mvan_0429|M.vanbaalenii_PYR-1 TVELSAVVTETAKYIVDRPRPDTAMVSALSTSFPSGHALGVMVSVAALLT
MSMEG_0634|M.smegmatis_MC2_155 SVELSGLVTQLAKLASDRPRPPTALVYASWTSFPSGHALGVMVCVPALLA
TH_3242|M.thermoresistible__bu TVVFNGVLIEGAKWLADRPRPATALVPAWSTAFPSGHAVGVLLAVLALLT
Rv0308|M.tuberculosis_H37Rv CLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLT
Mb0316|M.bovis_AF2122/97 CLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLT
MMAR_0558|M.marinum_M CVPLNWIITMIAKGLADRPRPVTKLVAAHSASFPSGHALELTASVLAMLT
MUL_1222|M.ulcerans_Agy99 CVPLNWIVTMIAKGLADRPRPVTKLVAAHSASFPSGHALELTASVLAMLT
MAV_4854|M.avium_104 CAPCNELVTAGAKALVDRPRPPTALVGAASTSFPSGHALEATAGLLAMTL
. :: ** *.** * :* * :******: : *:
Mflv_0312|M.gilvum_PYR-GCK VAVPAVAPSRRAWL-IALGVVIVVTVGVGRVILNVHHPSDVLAGWALGYA
MAB_0200c|M.abscessus_ATCC_199 VFTPKVVAAWRPWL-GVLGGVLILLIGISRVLLNVHNPSDVLAGWALGYA
Mvan_0429|M.vanbaalenii_PYR-1 VVLPVVRPALRGWL-VALGIAVILVVGIGRVVLNVHHPSDVIAGWALGYA
MSMEG_0634|M.smegmatis_MC2_155 LVWPLLRGAWRGWA-VAAGALVIVAIGVGRVVLNVHHPSDVVAGWALGYA
TH_3242|M.thermoresistible__bu VFWPKIDR-RAGWT-LAA-AVVVFAIGAGRVVLNVHHPSDVLAGWALGYA
Rv0308|M.tuberculosis_H37Rv VLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYL
Mb0316|M.bovis_AF2122/97 VLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYL
MMAR_0558|M.marinum_M FLLPMIRVHWMRILAVVVGALSVLLVGISRVALNVHHPSDVIAGWALGYV
MUL_1222|M.ulcerans_Agy99 FLLPMIRVHWMRILAVVVGALSVLLVGISRVALNVHHPSDVIAGWALGYV
MAV_4854|M.avium_104 FALPMLN-RVLRGLLVAAVAVALPAVGLSRVMLNVHYPSDVLAGWSLGYL
. * : . : :* .** **** *:**:***:***
Mflv_0312|M.gilvum_PYR-GCK YFLVCLR--LVPPAT-LTRRDE------------TPAELDIAR
MAB_0200c|M.abscessus_ATCC_199 YFIVCLL--ALPPWT-VTAADG------------TPPAPGNAP
Mvan_0429|M.vanbaalenii_PYR-1 YFVACLL--LVWPSVPVIERAE------------KPAVLDNAH
MSMEG_0634|M.smegmatis_MC2_155 FFVVCLL--LAPPYPDVRARGE------------IPEVRGIAT
TH_3242|M.thermoresistible__bu WFVGCYLGCLRPTWPDRPARAEP-----VTGGARTPAGPDSAP
Rv0308|M.tuberculosis_H37Rv YFLVCLC-VFRPPSIFGAQRASHALSPPVEVSRQPEPEVDTAR
Mb0316|M.bovis_AF2122/97 YFLVCLC-VFRPPSIFGAQRASHALSPPVEVSRQPEPEVDTAR
MMAR_0558|M.marinum_M YFLFWLW-VLR----------------PVPVAEQEPAELVSAG
MUL_1222|M.ulcerans_Agy99 YFLFWLW-VLR----------------PVPVAEQEPAELVSAG
MAV_4854|M.avium_104 YFLLCLL-VFR------------------------PSAPDRSG
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