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RILAMTRAHNAGRTLAATLDSLAVFSDDIYVIDDRSTDDTAEILANHPAVTNVVRARPDLPPTPWLIPES AGLELLYRMADFCRPDWVMMVDADWLVETDIDLRAVLARTPDDIVALMCPMVSRWDDPEYPDLIPVMGTA EALRGPLWRWYPGLRAGGKLMHNPHWPANITDHGRIGQLPGVRLVHSGWSTLAERILRVEHYLRLDPDYR FNFGVAYDRSLLFGYALDEVDLLKADYRRRIRGDFDPLEPGGRLPIDREPRAIGRGYGPHAGGFHPGVDF ATDPGTPVYAVASGAVSAIDEVDGLVSLTIARCELDVVYVFRPGDEGRLVLGDRIAAGAQLGTIGAQGES ADGYLHFEVRTQDGHVNPVRYLANMGLRPWPPPGRLRAVSGSYPPATPCTITAEDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3786c | - | - | 100% (407) | hypothetical protein Rv3786c |
| M. tuberculosis H37Rv | Rv0950c | - | 3e-09 | 33.63% (113) | hypothetical protein Rv0950c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3815c | - | 0.0 | 100.00% (407) | hypothetical protein Mb3815c |
| M. gilvum PYR-GCK | Mflv_1864 | - | 3e-10 | 33.91% (115) | peptidase M23B |
| M. leprae Br4923 | MLBr_00154 | - | 4e-09 | 30.36% (112) | hypothetical protein MLBr_00154 |
| M. abscessus ATCC 19977 | MAB_1055c | - | 6e-11 | 33.63% (113) | hypothetical protein MAB_1055c |
| M. marinum M | MMAR_5347 | - | 0.0 | 85.54% (408) | hypothetical protein MMAR_5347 |
| M. avium 104 | MAV_1073 | - | 2e-11 | 35.40% (113) | M23 peptidase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5526 | - | 1e-12 | 33.91% (115) | peptidoglycan-binding LysM |
| M. thermoresistible (build 8) | TH_1774 | - | 6e-09 | 32.17% (115) | peptidoglycan-binding LysM |
| M. ulcerans Agy99 | MUL_4721 | - | 4e-09 | 33.63% (113) | hypothetical protein MUL_4721 |
| M. vanbaalenii PYR-1 | Mvan_3705 | - | 6e-11 | 31.86% (113) | peptidase M23B |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1864|M.gilvum_PYR-GCK -------------------MPQHRLPRSRAALTTPGLSEVTDIIPFDEFG
MSMEG_5526|M.smegmatis_MC2_155 --------------------MTDIIP----------FSEFS--KAFDQFA
TH_1774|M.thermoresistible__bu ------LAKHRAVSPAGDSTDAHRHPRQG---FDPHPAEITEIIPLSGFG
MAV_1073|M.avium_104 -----------------MRVG--RAPGAR--SAEPHRTEVTEILPLDGFD
MUL_4721|M.ulcerans_Agy99 --------MSQHRYARTAVVGNPRTSRDR--WLQHHRNEVTEIIPLDG--
MLBr_00154|M.leprae_Br4923 -----------------MAAEAVRSFRNR--WLNHQRNDVTEIIPVDGFD
MAB_1055c|M.abscessus_ATCC_199 -----------------MPIDEFGLSDALE-RPELEDYDVYEDAPEEG--
Mvan_3705|M.vanbaalenii_PYR-1 -------------------MVHHRIARPDA-AADRGATDVTEIIAFGEFG
Rv3786c|M.tuberculosis_H37Rv MRILAMTRAHNAGRTLAATLDSLAVFSDDIYVIDDRSTDDTAEILANHPA
Mb3815c|M.bovis_AF2122/97 MRILAMTRAHNAGRTLAATLDSLAVFSDDIYVIDDRSTDDTAEILANHPA
MMAR_5347|M.marinum_M MRILAVTRAHNAGRTLVRTLDSLAAFSDDIYVIDDRSTDDTAEILANHPA
:
Mflv_1864|M.gilvum_PYR-GCK -----ALGDI-DDLEFLQDA-------AFGRDAEVIDAPELDDCHDTDDL
MSMEG_5526|M.smegmatis_MC2_155 -----ALDTQ-ISSAYDNLS-------AFEREARVIEAPELDDLNDTDDL
TH_1774|M.thermoresistible__bu -----RLSDLGADTDFYGDAWDDEWDVAFDRESEVVSAPELDDL-DPDAE
MAV_1073|M.avium_104 ----FDDLDFCDDAGDHGDLDFST-DSPFDNEAQVLLAPELDDLNETDDL
MUL_4721|M.ulcerans_Agy99 ----FDELELADLD----DLDFG--DPEFDTGRQLLQAPELDDLDEIDNL
MLBr_00154|M.leprae_Br4923 DFDDLYDLDFAEID----ELQFSDDDYNFCNETQVLLASEIDDLQDIDSL
MAB_1055c|M.abscessus_ATCC_199 -------AEIEDQT----ALDQLEQDWEEDTDEADRIRASIEATADWFAA
Mvan_3705|M.vanbaalenii_PYR-1 -----ALMDMASCR-----------SDPFAIDFEVLSAPELDDLNDLADE
Rv3786c|M.tuberculosis_H37Rv VT---NVVRARPDLPPTPWLIPESAGLELLYRMADFCRPDWVMMVDADWL
Mb3815c|M.bovis_AF2122/97 VT---NVVRARPDLPPTPWLIPESAGLELLYRMADFCRPDWVMMVDADWL
MMAR_5347|M.marinum_M VT---NVVRARSDLPATPWLIPESTGLELLYRMADFCRPDWVMMVDADWL
.. :
Mflv_1864|M.gilvum_PYR-GCK TPLRLAVPAEFRAEP------AAARR--ASTRAYRDSHTDVSDGSAKTDV
MSMEG_5526|M.smegmatis_MC2_155 EPVRLDIPSEFLADARDAGERSASRRKRNATHAYRDSHTDVSDGTAATDV
TH_1774|M.thermoresistible__bu APLRLVVPSEFRPDP---------RDERPSGHAYRDSHTDVSDGTAATDV
MAV_1073|M.avium_104 RPLWLAAPVTEVLPR----------------TTVAARTERRPERPRGADV
MUL_4721|M.ulcerans_Agy99 IPAWLATP-SPVLVG----------------ATSEALPEPSAAVPPAANV
MLBr_00154|M.leprae_Br4923 ASEPLAAS-----------------------------------ANVAPNF
MAB_1055c|M.abscessus_ATCC_199 SAARTRDP-----------------------------------RDTPTDK
Mvan_3705|M.vanbaalenii_PYR-1 SPRLLLAPTGSTNTAP---------PTVPIHVGGAHLRECPRPSRRALSG
Rv3786c|M.tuberculosis_H37Rv VETDIDLRAVLARTP---------DDIVALMCPMVSRWDDPEYPDLIPVM
Mb3815c|M.bovis_AF2122/97 VETDIDLRAVLARTP---------DDIVALMCPMVSRWDDPEYPDLIPVM
MMAR_5347|M.marinum_M VETDIDVRAALARTP---------EDVAALLCPIVSSWDDPEYPELIPVM
Mflv_1864|M.gilvum_PYR-GCK IDMRAHKGQHRK--TEV-PVKGRLVVAAMAVGATAAGAYTMTKNVPAAPA
MSMEG_5526|M.smegmatis_MC2_155 IDMTGRRGAHRK--ETTGALKSRLMIAAVAAGATAAGAYSFGNGTEAQAA
TH_1774|M.thermoresistible__bu IAIG-RRGQHRKP-EPTSAGKGRLMIAAMAAGATAAGAYSVVNGDDEKSS
MAV_1073|M.avium_104 VGVARRGGQHRKQ-PTSAA-RGRLLISAMAAGAAAAAAHTATSHADTPKT
MUL_4721|M.ulcerans_Agy99 APAPRRGGQHRKQ-STSAV-KGRLLIGSMAAGAAAAAAHTVTHQSDVTSM
MLBr_00154|M.leprae_Br4923 TSAPRRPCQHRKQ-PTSAT-RGRLLISAMAAGAMATAAHTVISHDDIPKT
MAB_1055c|M.abscessus_ATCC_199 LPRISSGGVHRRR-EIGQVGKTRLALAAMAAGAAAAAGYNALSEHDA---
Mvan_3705|M.vanbaalenii_PYR-1 SNVRASGGAHRKTPEAAGAAHSRLVITAIAVGAIAAAANAADDATEAQQP
Rv3786c|M.tuberculosis_H37Rv GTAEALRGPLWRWYPGLRAGGKLMHNPHWPANITDHGRIGQLPGVRLVHS
Mb3815c|M.bovis_AF2122/97 GTAEALRGPLWRWYPGLRAGGKLMHNPHWPANITDHGRIGQLPGVRLVHS
MMAR_5347|M.marinum_M GTAEALRGPFWRWSPGLRAGIKLMHNPHWPANITDHGRIGRLEGVRLVHD
: : ... .
Mflv_1864|M.gilvum_PYR-GCK ETVLASDSTTLGDGTVITGSVDGMQI-VSVAPASNSTVHAEEITKAAAFA
MSMEG_5526|M.smegmatis_MC2_155 DDTVLATGQTTVDGASVSGSNDGMQI-VSVASNISSAVHAEEITKAAAFA
TH_1774|M.thermoresistible__bu TDATVLAADQAAMPDAIDGATGGMQI-VTVAQPAKAIVHAEEITKAAAFA
MAV_1073|M.avium_104 DAVLTANASSLTGGAGGSNTVRGPQV-IAAEPAATAALHNQELAKGVAFA
MUL_4721|M.ulcerans_Agy99 DTVLTANASALIGGSD-SNEARGVQV-IAAQPATNVEAHKAEFARGVAFA
MLBr_00154|M.leprae_Br4923 ETVLTANASALS-GATVSDATQGVQV-ITVHPAASTAVHNEEHAKGTAFA
MAB_1055c|M.abscessus_ATCC_199 ATAADHHGLALG-NSAAVMATHGPQL-VSAPLATDASVTDEQLAKATAFA
Mvan_3705|M.vanbaalenii_PYR-1 VLVADTAASPAALPGP-----SGMQI-VPVANSFDAGIHRQELANGTAYA
Rv3786c|M.tuberculosis_H37Rv GWSTLAERILRVEHYLRLDPDYRFNFGVAYDRSLLFGYALDEVDLLKADY
Mb3815c|M.bovis_AF2122/97 GWSTLAERILRVEHYLRLDPDYRFNFGVAYDRSLLFGYALDEVDLLKADY
MMAR_5347|M.marinum_M GWSTLAERILRVEHYLRLDPDYRHNFGVAYDRSLLFGYALDEVDLLKADY
:. :. : *
Mflv_1864|M.gilvum_PYR-GCK QERAEREARLTKPQFVMPTTG---VWTSGFGYRWGVLHAGIDIANAIGTP
MSMEG_5526|M.smegmatis_MC2_155 QERAEREARLSRPLFVMPTKG---VWTSGFGYRWGVLHGGIDIANSIGTP
TH_1774|M.thermoresistible__bu QERAEREARLARPQFVMPTTG---VWTSGFGYRWGVLHGGIDIANSVGTP
MAV_1073|M.avium_104 NDRAQREARLQQPLYVMPTKG---IFTSNFGYRWGVLHAGIDLANSIGTP
MUL_4721|M.ulcerans_Agy99 QERAQREARLQQPLYVMPTKG---IFTSNFGYRWGVLHAGIDLANSIGTP
MLBr_00154|M.leprae_Br4923 HERAQREARLSQPLYVMPTKG---IFTSNFGYRWGVLHAGIDLANAIGTP
MAB_1055c|M.abscessus_ATCC_199 TERADREKRLLAPRFVMPTNG---TFTSGFGYRWGALHGGIDIANSIGTP
Mvan_3705|M.vanbaalenii_PYR-1 QERAQREARLRRPQFAFPSRG---ILTSGFGARWGTLHAGLDIANAVGTP
Rv3786c|M.tuberculosis_H37Rv RRRIRGDFDPLEPGGRLPIDREPRAIGRGYGPHAGGFHPGVDFATDPGTP
Mb3815c|M.bovis_AF2122/97 RRRIRGDFDPLEPGGRLPIDREPRAIGRGYGPHAGGFHPGVDFATDPGTP
MMAR_5347|M.marinum_M QRRIRGDFDPLEPGGRLPIDREPRAIGRGYGQRAGGFHPGVDFAADPGTP
* : * :* .:* : * :* *:*:* ***
Mflv_1864|M.gilvum_PYR-GCK VLAAADGIVIASGAEGGYGNAVKLR-HADGTVTLYGHNSSLLVSVGERVM
MSMEG_5526|M.smegmatis_MC2_155 IYAASDGVVTDVGPTAGYGAWVKIR-HSDGTVTLYGHINTWLVSVGERVM
TH_1774|M.thermoresistible__bu ILAAADGVVIETGPQGGYGIWVKLR-HYDGTVTVYAHLSSVLVNVGQRVM
MAV_1073|M.avium_104 IYAVSDGVVIEAGPAGGYGMLVKLR-HADGTVTLYGHINTALVSVGERVM
MUL_4721|M.ulcerans_Agy99 IYAVSDGLVIDAGPTAGYGMWVKIR-HADGTVTLYGHVNTTLVNVGQRVM
MLBr_00154|M.leprae_Br4923 ILAVSDGVVIDVGPTAGYGMWVKLR-HADGTVTLYGHVNTTLVNVGQYVV
MAB_1055c|M.abscessus_ATCC_199 IVAAADGVVIATGPTAGYGAWVKIR-HSDGTVTLYGHINTWEVSVGQRVM
Mvan_3705|M.vanbaalenii_PYR-1 IYAASDGEVIASGPTPGFGMWVKIR-AADGTVTLYGHIDTTNVQTGQRVM
Rv3786c|M.tuberculosis_H37Rv VYAVASGAVSAIDEVDGLVSLTIAR-CELDVVYVFRPGDEGRLVLGDRIA
Mb3815c|M.bovis_AF2122/97 VYAVASGAVSAIDEVDGLVSLTIAR-CELDVVYVFRPGDEGRLVLGDRIA
MMAR_5347|M.marinum_M VYAVVSGAVSAIDDVDGLLSMTIAQGPDLDVVYVFRPVERNGMSVGDQVR
: *. .* * . * . : ..* :: . : *: :
Mflv_1864|M.gilvum_PYR-GCK AGDQIAKMGNTGNSTGPHLHFEVHLNGTDRVDPTGWLAKRGLSP------
MSMEG_5526|M.smegmatis_MC2_155 AGDQIATMGNRGYSTGPHLHFEVLTNGTNRIDPVGWLAKRGLSP------
TH_1774|M.thermoresistible__bu AGDQIARMGNTGNSTGPHLHFEVLLDGVNRVDPAAWLAKRGVGPN-----
MAV_1073|M.avium_104 AGDQIATMGNRGNSTGPHLHFEVLQGGTERIDPVPWLAKRGLMV------
MUL_4721|M.ulcerans_Agy99 AGDHIATMGNRGFSTGPHLHFEVLQGGTERIDPVPWLAKRGLNV------
MLBr_00154|M.leprae_Br4923 AGDQIATMGTRGNSTGPHLHFEVLLSGSERIDPVPWLAKRGIYV------
MAB_1055c|M.abscessus_ATCC_199 AGDRIATIGNRGNSTGPHLHFEVLLGGSQRIDPQGWLANKGLTF------
Mvan_3705|M.vanbaalenii_PYR-1 AGDQIATMGNRGNSTGPHLHFEVHLNGTDKIDPMAWLGERGIPN------
Rv3786c|M.tuberculosis_H37Rv AGAQLGTIGAQGESADGYLHFEVRTQDG-HVNPVRYLANMGLRPWPPPGR
Mb3815c|M.bovis_AF2122/97 AGAQLGTIGAQGESADGYLHFEVRTQDG-HVNPVRYLANMGLRPWPPPGR
MMAR_5347|M.marinum_M AGARLGAIGAEGDSGDGYLHFEVRHRGS-HVNPLRYLANLGLRPWPPPGR
** ::. :* * * . :***** . :::* :*.: *:
Mflv_1864|M.gilvum_PYR-GCK -----GGYVG-----------
MSMEG_5526|M.smegmatis_MC2_155 -----GSYVG-----------
TH_1774|M.thermoresistible__bu -----SGYMR-----------
MAV_1073|M.avium_104 -----GNYAG-----------
MUL_4721|M.ulcerans_Agy99 -----GNYAG-----------
MLBr_00154|M.leprae_Br4923 -----GNYTG-----------
MAB_1055c|M.abscessus_ATCC_199 -----TRFGD-----------
Mvan_3705|M.vanbaalenii_PYR-1 ------D--------------
Rv3786c|M.tuberculosis_H37Rv LRAVSGSYPPATPCTITAEDR
Mb3815c|M.bovis_AF2122/97 LRAVSGSYPPATPCTITAEDR
MMAR_5347|M.marinum_M LRAVSGSYPPATPCTITAPQR