For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PKLSAGVLLYRARAGVVDVLLAHPGGPFWAGKDDGAWSIPKGEYTGGEDPWLAARREFSEEIGLCVPDGP RIDFGSLKQSGGKVVTVFGVRADLDITDARSSTFELDWPKGSGKMRKFPEVDRVSWFPVARARTKLLKGQ RGFLDRLMAHPAVAGLSEGPESLPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3733c | - | - | 100% (166) | hypothetical protein Rv3733c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3760c | - | 2e-96 | 100.00% (166) | hypothetical protein Mb3760c |
| M. gilvum PYR-GCK | Mflv_3428 | - | 9e-54 | 64.19% (148) | NUDIX hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3291 | - | 5e-06 | 30.43% (138) | MutT/NUDIX hydrolase |
| M. marinum M | MMAR_5270 | - | 5e-73 | 78.12% (160) | hypothetical protein MMAR_5270 |
| M. avium 104 | MAV_0356 | - | 1e-72 | 78.75% (160) | nudix hydrolase |
| M. smegmatis MC2 155 | MSMEG_3679 | - | 1e-62 | 68.12% (160) | phosphohydrolase |
| M. thermoresistible (build 8) | TH_2220 | - | 2e-56 | 61.01% (159) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4344 | - | 4e-54 | 76.67% (120) | hypothetical protein MUL_4344 |
| M. vanbaalenii PYR-1 | Mvan_3182 | - | 7e-57 | 66.22% (148) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3733c|M.tuberculosis_H37Rv ---------MPKLSAGVLLYRARAG-VVDVLLAHPGGPFWAGKDDGAWSI
Mb3760c|M.bovis_AF2122/97 ---------MPKLSAGVLLYRARAG-VVDVLLAHPGGPFWAGKDDGAWSI
MAV_0356|M.avium_104 ---------MPKLSAGVLLYRTGDG-VVEVLIAHPGGPFWARKDDGAWSI
MMAR_5270|M.marinum_M ---------MPKLSAGVLVYRASAG-VLELLIVHPGGPFWARKDDGAWSI
MUL_4344|M.ulcerans_Agy99 ---------MPKLSAGVLVYRAAAG-VLELLIVHPGGPFWARKDDGAWSI
Mflv_3428|M.gilvum_PYR-GCK ---------MPKLSAGLLLFRETDG-VVEVLLGHPGGPFWARKDEGAWSI
Mvan_3182|M.vanbaalenii_PYR-1 ---------MPKLSAGLLLFRESDG-VLEVLLGHPGGPFWARKDEGAWSI
TH_2220|M.thermoresistible__bu ---------VPKRSAGLLVYRIVDG-VVEVLICHPGGPYWASKDAGVWSI
MSMEG_3679|M.smegmatis_MC2_155 ------MNGMPKLSAGVLLYRVVDD-VVEVLIAHPGGPFWARRDDGAWSV
MAB_3291|M.abscessus_ATCC_1997 MPDPISRTGAAVLAAGAALWRHQEHPEQDNAAGAIEVALVHRPRYDDWSL
. :** ::* : . . **:
Rv3733c|M.tuberculosis_H37Rv PKGEYTGGEDPWLAARREFSEEIGLCVPDGPRI-DFGSLKQSGGKVVTVF
Mb3760c|M.bovis_AF2122/97 PKGEYTGGEDPWLAARREFSEEIGLCVPDGPRI-DFGSLKQSGGKVVTVF
MAV_0356|M.avium_104 PKGEYDEGEEPWPAARREFAEELGLAVPPGERI-DLGTLKQSGGKLVTVF
MMAR_5270|M.marinum_M PKGEYTQDEDPWVAARREFAEEIGLPVPDGARI-DLGSVKQAGGKVVTAF
MUL_4344|M.ulcerans_Agy99 PKGEYTQDEDPWVAARREFAEEIGLPVPDGARI-DLGSVKQAGGKVVTAF
Mflv_3428|M.gilvum_PYR-GCK PKGEYADGDDPWAVAQREFTEETGKPVPAGPPI-GLAPVRQPGGKVVTAF
Mvan_3182|M.vanbaalenii_PYR-1 PKGEYTEGEDPWTVAQREFTEELGKPPPTGPRI-DLAAVRQPGGKVVTAF
TH_2220|M.thermoresistible__bu PKGEYEPDEDPWAVARREFIEEVGKQPPSGPAV-RFDPVRQPSGKIVTAF
MSMEG_3679|M.smegmatis_MC2_155 PKGEYTDDEDRWAAAQREFAEELGSPPPDGPRR-ELTPVRQSGGKVVTAF
MAB_3291|M.abscessus_ATCC_1997 PKGKLDPGETAAIAAVREIAEETGFTARLGRRLPSVSYPVSQGTKRVKYW
***: .: .* **: ** * * . . . * *. :
Rv3733c|M.tuberculosis_H37Rv GVRADLDITDARSSTFELDWP-----------------------------
Mb3760c|M.bovis_AF2122/97 GVRADLDITDARSSTFELDWP-----------------------------
MAV_0356|M.avium_104 AVHGDLDVTEARSNTFALEWP-----------------------------
MMAR_5270|M.marinum_M AVRGDLDVTEAHSNTFELEWP-----------------------------
MUL_4344|M.ulcerans_Agy99 AVRGDLDVTEAHSNTFELEWP-----------------------------
Mflv_3428|M.gilvum_PYR-GCK AVRGDLDLDGTFSNTFTLVWP-----------------------------
Mvan_3182|M.vanbaalenii_PYR-1 AVRGDLDLCDAVSNTFTLEWP-----------------------------
TH_2220|M.thermoresistible__bu AVRGDVDLEGAVSNTFEMEWP-----------------------------
MSMEG_3679|M.smegmatis_MC2_155 AVRGDFDVTSARSNTFEMEWP-----------------------------
MAB_3291|M.abscessus_ATCC_1997 AAEALDGKFEANDEVDELRWLPVKDAIKTVSYAVDRKVLRNFAKHQIDTR
.... . : ... : *
Rv3733c|M.tuberculosis_H37Rv ----------------KGSGKMRKFP------------------------
Mb3760c|M.bovis_AF2122/97 ----------------KGSGKMRKFP------------------------
MAV_0356|M.avium_104 ----------------KGSGTLREFP------------------------
MMAR_5270|M.marinum_M ----------------KGSGKVREFP------------------------
MUL_4344|M.ulcerans_Agy99 ----------------KGSGRVREFP------------------------
Mflv_3428|M.gilvum_PYR-GCK ----------------RGSGTVREFP------------------------
Mvan_3182|M.vanbaalenii_PYR-1 ----------------RGSGIFKEFP------------------------
TH_2220|M.thermoresistible__bu ----------------KGSGQIREFP------------------------
MSMEG_3679|M.smegmatis_MC2_155 ----------------KGSGRMREFP------------------------
MAB_3291|M.abscessus_ATCC_1997 TLIIVRHAKAGRKERYSGDDTLRPLDKKGRAQAEALTGQLLAFGASAIHA
*.. .: :
Rv3733c|M.tuberculosis_H37Rv ---------------EVDRVSWFPVARARTKLLKGQRGFLDRLMAHPAVA
Mb3760c|M.bovis_AF2122/97 ---------------EVDRVSWFPVARARTKLLKGQRGFLDRLMAHPAVA
MAV_0356|M.avium_104 ---------------EVDRVGWFPVAAARTKLLKSQHGFLDRLMAQPAVA
MMAR_5270|M.marinum_M ---------------EVDRVGWFPVATARGKLLRGQRDFLDRLMADPSVA
MUL_4344|M.ulcerans_Agy99 ---------------VAG-SARHPAGPQAGSPAPKDHE------------
Mflv_3428|M.gilvum_PYR-GCK ---------------EIDRVEWFDLATARVKLLKGQRPLLDELEKV--LA
Mvan_3182|M.vanbaalenii_PYR-1 ---------------EIDRVAWFGLAEARAKLLKGQLPLLDRLEEA--LG
TH_2220|M.thermoresistible__bu ---------------EIDRVGWFPVAVAREKLVKGQRPLLDRLMELPELA
MSMEG_3679|M.smegmatis_MC2_155 ---------------EIDRAGWFPVAVARRKLLAGQRPLLDELMAAPELA
MAB_3291|M.abscessus_ATCC_1997 ADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWADRKRAHRRVLEIAELD
. .
Rv3733c|M.tuberculosis_H37Rv G-------------------LSEGPESLPR--------------------
Mb3760c|M.bovis_AF2122/97 G-------------------LSEGPESLPR--------------------
MAV_0356|M.avium_104 G-------------------LSEGT-------------------------
MMAR_5270|M.marinum_M G-------------------LGEG--------------------------
MUL_4344|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3428|M.gilvum_PYR-GCK ---------------------HDGPDASRSR-------------------
Mvan_3182|M.vanbaalenii_PYR-1 ---------------------RGGPDVSRSR-------------------
TH_2220|M.thermoresistible__bu GCAEDQAT---------DGPAADGPAGSRSH-------------------
MSMEG_3679|M.smegmatis_MC2_155 G-------------------YREGD-------------------------
MAB_3291|M.abscessus_ATCC_1997 GIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRKGSMWVLSMRGQKLLAA
Rv3733c|M.tuberculosis_H37Rv -----------
Mb3760c|M.bovis_AF2122/97 -----------
MAV_0356|M.avium_104 -----------
MMAR_5270|M.marinum_M -----------
MUL_4344|M.ulcerans_Agy99 -----------
Mflv_3428|M.gilvum_PYR-GCK -----------
Mvan_3182|M.vanbaalenii_PYR-1 -----------
TH_2220|M.thermoresistible__bu -----------
MSMEG_3679|M.smegmatis_MC2_155 -----------
MAB_3291|M.abscessus_ATCC_1997 DHLDSPLPAGS