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MPKLSAGVLLYRTGDGVVEVLIAHPGGPFWARKDDGAWSIPKGEYDEGEEPWPAARREFAEELGLAVPPG ERIDLGTLKQSGGKLVTVFAVHGDLDVTEARSNTFALEWPKGSGTLREFPEVDRVGWFPVAAARTKLLKS QHGFLDRLMAQPAVAGLSEGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0356 | - | - | 100% (161) | nudix hydrolase |
| M. avium 104 | MAV_3835 | - | 4e-07 | 32.41% (145) | hydrolase, NUDIX family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3760c | - | 8e-73 | 78.75% (160) | hypothetical protein Mb3760c |
| M. gilvum PYR-GCK | Mflv_3428 | - | 2e-55 | 65.54% (148) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv3733c | - | 9e-73 | 78.75% (160) | hypothetical protein Rv3733c |
| M. leprae Br4923 | MLBr_01682 | - | 0.0001 | 39.44% (71) | hypothetical protein MLBr_01682 |
| M. abscessus ATCC 19977 | MAB_3291 | - | 5e-06 | 33.91% (115) | MutT/NUDIX hydrolase |
| M. marinum M | MMAR_5270 | - | 2e-72 | 78.12% (160) | hypothetical protein MMAR_5270 |
| M. smegmatis MC2 155 | MSMEG_3679 | - | 5e-64 | 70.62% (160) | phosphohydrolase |
| M. thermoresistible (build 8) | TH_2220 | - | 6e-57 | 62.26% (159) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4344 | - | 4e-54 | 78.33% (120) | hypothetical protein MUL_4344 |
| M. vanbaalenii PYR-1 | Mvan_3182 | - | 1e-58 | 68.24% (148) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3760c|M.bovis_AF2122/97 -------------MPKLSAGVLLYR--------ARAGVVDVLLAHPGGPF
Rv3733c|M.tuberculosis_H37Rv -------------MPKLSAGVLLYR--------ARAGVVDVLLAHPGGPF
MAV_0356|M.avium_104 -------------MPKLSAGVLLYR--------TGDGVVEVLIAHPGGPF
MMAR_5270|M.marinum_M -------------MPKLSAGVLVYR--------ASAGVLELLIVHPGGPF
MUL_4344|M.ulcerans_Agy99 -------------MPKLSAGVLVYR--------AAAGVLELLIVHPGGPF
Mflv_3428|M.gilvum_PYR-GCK -------------MPKLSAGLLLFR--------ETDGVVEVLLGHPGGPF
Mvan_3182|M.vanbaalenii_PYR-1 -------------MPKLSAGLLLFR--------ESDGVLEVLLGHPGGPF
TH_2220|M.thermoresistible__bu -------------VPKRSAGLLVYR--------IVDGVVEVLICHPGGPY
MSMEG_3679|M.smegmatis_MC2_155 ----------MNGMPKLSAGVLLYR--------VVDDVVEVLIAHPGGPF
MLBr_01682|M.leprae_Br4923 MAIWNSSCQWPKSQIVYAAGAVLWR------PGNSDPAVEIAVIHR----
MAB_3291|M.abscessus_ATCC_1997 MPDPIS----RTGAAVLAAGAALWRHQEHPEQDNAAGAIEVALVHR----
:** ::* .::: : *
Mb3760c|M.bovis_AF2122/97 WAGKDDGAWSIPKGEYTGGEDPWLAARREFSEEIGLCVPDGPRIDFGSLK
Rv3733c|M.tuberculosis_H37Rv WAGKDDGAWSIPKGEYTGGEDPWLAARREFSEEIGLCVPDGPRIDFGSLK
MAV_0356|M.avium_104 WARKDDGAWSIPKGEYDEGEEPWPAARREFAEELGLAVPPGERIDLGTLK
MMAR_5270|M.marinum_M WARKDDGAWSIPKGEYTQDEDPWVAARREFAEEIGLPVPDGARIDLGSVK
MUL_4344|M.ulcerans_Agy99 WARKDDGAWSIPKGEYTQDEDPWVAARREFAEEIGLPVPDGARIDLGSVK
Mflv_3428|M.gilvum_PYR-GCK WARKDEGAWSIPKGEYADGDDPWAVAQREFTEETGKPVPAGPPIGLAPVR
Mvan_3182|M.vanbaalenii_PYR-1 WARKDEGAWSIPKGEYTEGEDPWTVAQREFTEELGKPPPTGPRIDLAAVR
TH_2220|M.thermoresistible__bu WASKDAGVWSIPKGEYEPDEDPWAVARREFIEEVGKQPPSGPAVRFDPVR
MSMEG_3679|M.smegmatis_MC2_155 WARRDDGAWSVPKGEYTDDEDRWAAAQREFAEELGSPPPDGPRRELTPVR
MLBr_01682|M.leprae_Br4923 -PRYDD--WSLSKGKVDPGETAPMAAVREVFEETGHHATLGARLVVVNYP
MAB_3291|M.abscessus_ATCC_1997 -PRYDD--WSLPKGKLDPGETAAIAAVREIAEETGFTARLGRRLPSVSYP
. * **:.**: .: .* **. ** * *
Mb3760c|M.bovis_AF2122/97 Q-SGGKVVTVFGVRADLDITDARSSTFELDWP------------KGSGKM
Rv3733c|M.tuberculosis_H37Rv Q-SGGKVVTVFGVRADLDITDARSSTFELDWP------------KGSGKM
MAV_0356|M.avium_104 Q-SGGKLVTVFAVHGDLDVTEARSNTFALEWP------------KGSGTL
MMAR_5270|M.marinum_M Q-AGGKVVTAFAVRGDLDVTEAHSNTFELEWP------------KGSGKV
MUL_4344|M.ulcerans_Agy99 Q-AGGKVVTAFAVRGDLDVTEAHSNTFELEWP------------KGSGRV
Mflv_3428|M.gilvum_PYR-GCK Q-PGGKVVTAFAVRGDLDLDGTFSNTFTLVWP------------RGSGTV
Mvan_3182|M.vanbaalenii_PYR-1 Q-PGGKVVTAFAVRGDLDLCDAVSNTFTLEWP------------RGSGIF
TH_2220|M.thermoresistible__bu Q-PSGKIVTAFAVRGDVDLEGAVSNTFEMEWP------------KGSGQI
MSMEG_3679|M.smegmatis_MC2_155 Q-SGGKVVTAFAVRGDFDVTSARSNTFEMEWP------------KGSGRM
MLBr_01682|M.leprae_Br4923 IGQHVKKVYYWAARSIEGQFVPGSEVDELLWLPVVDAMKKLDYVQDRKVL
MAB_3291|M.abscessus_ATCC_1997 VSQGTKRVKYWAAEALDGKFEANDEVDELRWLPVKDAIKTVSYAVDRKVL
* * :.... . . ... : * . .
Mb3760c|M.bovis_AF2122/97 RKFP---------------EVDRVSWFPVARARTKLLKGQRGFLDRLMAH
Rv3733c|M.tuberculosis_H37Rv RKFP---------------EVDRVSWFPVARARTKLLKGQRGFLDRLMAH
MAV_0356|M.avium_104 REFP---------------EVDRVGWFPVAAARTKLLKSQHGFLDRLMAQ
MMAR_5270|M.marinum_M REFP---------------EVDRVGWFPVATARGKLLRGQRDFLDRLMAD
MUL_4344|M.ulcerans_Agy99 REFP---------------VAG-SARHPAGPQAGSPAPKDHE--------
Mflv_3428|M.gilvum_PYR-GCK REFP---------------EIDRVEWFDLATARVKLLKGQRPLLDELEKV
Mvan_3182|M.vanbaalenii_PYR-1 KEFP---------------EIDRVAWFGLAEARAKLLKGQLPLLDRLEEA
TH_2220|M.thermoresistible__bu REFP---------------EIDRVGWFPVAVAREKLVKGQRPLLDRLMEL
MSMEG_3679|M.smegmatis_MC2_155 REFP---------------EIDRAGWFPVAVARRKLLAGQRPLLDELMAA
MLBr_01682|M.leprae_Br4923 RQFAKQPAYTRTVLIVRHGTAGRKSRLSEDDTKRPLDKQGRAQAEALIGQ
MAB_3291|M.abscessus_ATCC_1997 RNFAKHQIDTRTLIIVRHAKAGRKERYSGDDTLRPLDKKGRAQAEALTGQ
::*. .
Mb3760c|M.bovis_AF2122/97 PAVAG----------LSEGPESLPR-------------------------
Rv3733c|M.tuberculosis_H37Rv PAVAG----------LSEGPESLPR-------------------------
MAV_0356|M.avium_104 PAVAG----------LSEGT------------------------------
MMAR_5270|M.marinum_M PSVAG----------LGEG-------------------------------
MUL_4344|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3428|M.gilvum_PYR-GCK --LA------------HDGPDASRSR------------------------
Mvan_3182|M.vanbaalenii_PYR-1 --LG------------RGGPDVSRSR------------------------
TH_2220|M.thermoresistible__bu PELAGCAEDQATDGPAADGPAGSRSH------------------------
MSMEG_3679|M.smegmatis_MC2_155 PELAG----------YREGD------------------------------
MLBr_01682|M.leprae_Br4923 LLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRG
MAB_3291|M.abscessus_ATCC_1997 LLAFGASAIHAADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWADRKRA
Mb3760c|M.bovis_AF2122/97 --------------------------------------------------
Rv3733c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0356|M.avium_104 --------------------------------------------------
MMAR_5270|M.marinum_M --------------------------------------------------
MUL_4344|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3428|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3182|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2220|M.thermoresistible__bu --------------------------------------------------
MSMEG_3679|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01682|M.leprae_Br4923 LHRVLRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWV
MAB_3291|M.abscessus_ATCC_1997 HRRVLEIAELDGIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRKGSMWV
Mb3760c|M.bovis_AF2122/97 ------------------------
Rv3733c|M.tuberculosis_H37Rv ------------------------
MAV_0356|M.avium_104 ------------------------
MMAR_5270|M.marinum_M ------------------------
MUL_4344|M.ulcerans_Agy99 ------------------------
Mflv_3428|M.gilvum_PYR-GCK ------------------------
Mvan_3182|M.vanbaalenii_PYR-1 ------------------------
TH_2220|M.thermoresistible__bu ------------------------
MSMEG_3679|M.smegmatis_MC2_155 ------------------------
MLBr_01682|M.leprae_Br4923 LSLLAGQLVAVDHVGSTLAANVQP
MAB_3291|M.abscessus_ATCC_1997 LSMRGQKLLAADHLDSPLPAGS--