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VSESTPEVSSSYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWSGAPFAKWFVG GELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPL IPEAVIAMLACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPD CSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGKPKGIMHTSGGY LTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYG VTIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIGGGRTPLVDTWWQTETGS AMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARY WHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTD ETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISPIARPRDVHVVPELPKTRSGKIMRRLLRDVAENR ELGDTSTLLDPTVFDAIRAAK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3667 | acs | - | 100% (651) | acetyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv2384 | mbtA | 3e-33 | 28.26% (552) | bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase |
| M. tuberculosis H37Rv | Rv1427c | fadD12 | 5e-30 | 27.27% (495) | acyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3691 | acs | 0.0 | 99.85% (651) | acetyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_1380 | - | 0.0 | 71.82% (653) | acetyl-CoA synthetase |
| M. leprae Br4923 | MLBr_00134 | fadD22 | 5e-25 | 23.96% (530) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_0425c | - | 0.0 | 73.58% (651) | Acetyl-CoA synthetase |
| M. marinum M | MMAR_5155 | acs | 0.0 | 85.69% (650) | acetyl-coenzyme A synthetase Acs |
| M. avium 104 | MAV_0462 | acsA | 0.0 | 80.34% (651) | acetyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_6179 | - | 0.0 | 76.43% (649) | acetyl-coenzyme A synthetase |
| M. thermoresistible (build 8) | TH_0966 | acs | 0.0 | 75.42% (651) | ACETYL-COENZYME A SYNTHETASE ACS (ACETATE--CoA LIGASE) |
| M. ulcerans Agy99 | MUL_4241 | acs | 0.0 | 85.38% (650) | acetyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_5425 | - | 0.0 | 73.97% (653) | acetyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5155|M.marinum_M --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 MCCAIWSASRAPACSASQLSSSHAVRPSVVPDANPRAAPRYSPDLRIQCT
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5155|M.marinum_M --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 SGTPRPCGSSPLAIVTSRETARATTPSAVPNGASVSNSPCATAASTGAGA
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5155|M.marinum_M --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 LDPPVRSSISNSRRGPTSGSVRGRPRCSSSVRSAAASACSRASACIGARC
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5155|M.marinum_M --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 HTVTNEVAPPSSASATRIAPAVTGSGSPSADSCTAPPSSTADARAPRSAD
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5155|M.marinum_M --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 SAAVCGQPRRLTLCRCARPSASRASSQAAATPGSSNSGARGSGRSVITSH
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv ---------------------------------------MS-ESTPEVSS
Mb3691|M.bovis_AF2122/97 ---------------------------------------MS-ESTPEVSS
MMAR_5155|M.marinum_M ---------------------------------------MT-ATSAEEPS
MUL_4241|M.ulcerans_Agy99 ------------------------------MKLNIGDTPVT-ATSAEEPS
MAV_0462|M.avium_104 ---------------------------------------MT-ASNTANPP
Mflv_1380|M.gilvum_PYR-GCK ---------------------------------------MT-ETHVDIPS
Mvan_5425|M.vanbaalenii_PYR-1 -----------------------------MQRLVTTLTTMT-ETQLDAIA
MSMEG_6179|M.smegmatis_MC2_155 ASRPLIASSPTVQRNQTTVHQQTCEGPTCVQRSVTRLTAMSNPSHAEVPS
MAB_0425c|M.abscessus_ATCC_199 ---------------------------------------MT-ETSIE-PD
TH_0966|M.thermoresistible__bu ---------------------------------------MS-ETHTEAQS
MLBr_00134|M.leprae_Br4923 --------------------------------MRSENLAALLARQAAEAG
Rv3667|M.tuberculosis_H37Rv SYPPPAHFAEHANARAELYREAE---------------------------
Mb3691|M.bovis_AF2122/97 SYPPPAHFAEHANARAELYREAE---------------------------
MMAR_5155|M.marinum_M SYPPPAEFIEQANARAELYREAE---------------------------
MUL_4241|M.ulcerans_Agy99 SYPPPAEFIEQANARAELYREAE---------------------------
MAV_0462|M.avium_104 SYPPPPQFVEQANAGEQLYREAE---------------------------
Mflv_1380|M.gilvum_PYR-GCK SYPPDPGFAENANATEALYEQAD---------------------------
Mvan_5425|M.vanbaalenii_PYR-1 SYPPPPEFTESANATAELYDEAE---------------------------
MSMEG_6179|M.smegmatis_MC2_155 AYPPPADFAANANATGELYAEAE---------------------------
MAB_0425c|M.abscessus_ATCC_199 SYPPSPEFVATANATADLYQAAE---------------------------
TH_0966|M.thermoresistible__bu VYPPPAEFAAQSNATADLYREAE---------------------------
MLBr_00134|M.leprae_Br4923 WYDKPAYFAPDVVTHGQIHDGAVRLGEVLRNRGLSAGDRVLLCLPDSPDL
* . * : :: *
Rv3667|M.tuberculosis_H37Rv ---------EDRLAFWAK-QANRLSWTTP---FTEVLDWSGAPFAKWFVG
Mb3691|M.bovis_AF2122/97 ---------EDRLAFWAK-QANRLSWTTP---FTEVLDWSEAPFAKWFVG
MMAR_5155|M.marinum_M ---------EDRLAFWAK-QADRLSWATP---FGEVLDWSDAPFAKWFVG
MUL_4241|M.ulcerans_Agy99 ---------EDRLAFWAK-QADRLSWATP---FGEVLDWSDAPFANWFVG
MAV_0462|M.avium_104 ---------RDRLAFWAE-QANRLSWATP---FTEVLDWSRAPFAEWFAD
Mflv_1380|M.gilvum_PYR-GCK ---------ADRLEFWAE-QARRLAWETP---FDEVLDWSEAPFAKWFVG
Mvan_5425|M.vanbaalenii_PYR-1 ---------ADRLAFWAK-QANRLSWQTP---FTEVLDWSDAPFAKWFVG
MSMEG_6179|M.smegmatis_MC2_155 ---------KDRLAFWEK-QAKRLSWQTP---FTDVLDWSDAPFAKWFVG
MAB_0425c|M.abscessus_ATCC_199 ---------EDRLGFWEQ-QAGRLHWDEP---FGQVLDWSDAPFAKWFVG
TH_0966|M.thermoresistible__bu ---------ADRLAFWAR-QAERLTWAKP---FEQVLDWSEAPFAKWFVG
MLBr_00134|M.leprae_Br4923 VQLLLACLARGIMAFLANPELHRDDYAFPERDTAAALVITNGSLRDRFQS
. : * . : * : * .* : ..: . * .
Rv3667|M.tuberculosis_H37Rv GELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAA
Mb3691|M.bovis_AF2122/97 GELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAA
MMAR_5155|M.marinum_M GKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYADLQAEVSKAA
MUL_4241|M.ulcerans_Agy99 GKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYADLQAEVSKAA
MAV_0462|M.avium_104 GTLNVAYNCVDRHVQAGHGDRVAIHWEGESPGDQRSLTYSELYTQVCKAA
Mflv_1380|M.gilvum_PYR-GCK GTLNVAYNCVDRHVEAGNGDRVAIHWVGEPVEHSRDITYAELKDEVCRAA
Mvan_5425|M.vanbaalenii_PYR-1 GKLNVAYNCVDRHVEAGNGDRVAIHWEGEPVGDARDITYAQLKDEVCQAA
MSMEG_6179|M.smegmatis_MC2_155 GKINVAYNCVDRHVEAGNGDRVAIHWEGEPVGDARSITYAELKDEVCKAA
MAB_0425c|M.abscessus_ATCC_199 GKLNVAYNCVDRHVEAGNGDRVAIHWEGEP-GDTRTITYAELLAQVSQAA
TH_0966|M.thermoresistible__bu GRLNVAYNCVDRHVEAGNGDRVAIYWEGEPVGDSRTLTYAQLKDEVSKAA
MLBr_00134|M.leprae_Br4923 SNVVEPAELLSDATRVEPSDYEPVSGDAYAFATYTSGTTGKPKAAIHRHA
. : . : :. ... .* .: . . * .. : : *
Rv3667|M.tuberculosis_H37Rv NALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLG--IMHSVVFGGFTAA
Mb3691|M.bovis_AF2122/97 NALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLG--IMHSVVFGGFTAA
MMAR_5155|M.marinum_M NALTGLGLVAGDRVAIYLPLIPEAVIAMLACARLG--IMHSVVFGGFTAN
MUL_4241|M.ulcerans_Agy99 NALTGLGLVAGDRVAIYLPLIPEAVIAMLACARLG--IMHSVVFGGFTAN
MAV_0462|M.avium_104 NALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLG--VMHSVVFAGFTAK
Mflv_1380|M.gilvum_PYR-GCK NALTNLGLTAGDRVAIYMPMVPEAIIAMLACARLG--AMHSVVFAGFSAS
Mvan_5425|M.vanbaalenii_PYR-1 NAFAELGLKAGDRVAIYMPMVPEAIIAMLACARLG--AMHSVVFAGFSAS
MSMEG_6179|M.smegmatis_MC2_155 NALTDLGLVAGDRVAIYMPMIPEAIVAMLACARLG--VMHSVVFAGFSAS
MAB_0425c|M.abscessus_ATCC_199 NYLTELGLVSGDRVAIYMPMLPEAIVAMLACARLG--LMHSVVFAGFSAA
TH_0966|M.thermoresistible__bu NALTRLGLRTGDRVAIYMPMIPEAIISMLACARLG--VLHSVVFAGFSSS
MLBr_00134|M.leprae_Br4923 DPFTFVDAMCRKALRLTPQDIGLCSARMYFAYGLGNSVWFPLATGGSAVI
: :: :. . : : : . * . ** ..:. .* :
Rv3667|M.tuberculosis_H37Rv ALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAI----------
Mb3691|M.bovis_AF2122/97 ALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAI----------
MMAR_5155|M.marinum_M ALHARIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ-----------
MUL_4241|M.ulcerans_Agy99 TLHARIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ-----------
MAV_0462|M.avium_104 ALQARIADAAAKLLITSDGQFRRGKPAPLKDAADEAVAD-----------
Mflv_1380|M.gilvum_PYR-GCK ALKARIEDAQAKLVITTDGQYRRGSAVSLKTGVDEAIDGL----------
Mvan_5425|M.vanbaalenii_PYR-1 ALKARIEDAQTKLVVTTDGQYRRGSAVALKTAVDEAIESL----------
MSMEG_6179|M.smegmatis_MC2_155 ALRARIEDAEAKLVITSDGQYRRGKAASLKEAVDEAVA------------
MAB_0425c|M.abscessus_ATCC_199 ALRARIDDAQAKLVITSDGQWRRGTAAPLKSQVDEALGAAGPAT----SD
TH_0966|M.thermoresistible__bu ALTARIQDAEAKLLITADGQYRRGNAVPLKTNADEAVQ------------
MLBr_00134|M.leprae_Br4923 SSVPVSAESAAMLSTRFEPSVLYGVPSFFARVVGACSPDSFRSLRCVVTA
: . :: : * : . * . : .. .
Rv3667|M.tuberculosis_H37Rv ---PDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSE
Mb3691|M.bovis_AF2122/97 ---PDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSE
MMAR_5155|M.marinum_M ---PDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPEHTPEPFDAE
MUL_4241|M.ulcerans_Agy99 ---PDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPQHTPEPFDAE
MAV_0462|M.avium_104 ---PDSPVEHVVVVRRTGIDVSWTDGRDLWWHDVVDAAAPEHTPEPFPAE
Mflv_1380|M.gilvum_PYR-GCK --GEDSPVEHVLVVRRTGIDTPWTPDRDLWWDETVPEADTEHTPEAFDSE
Mvan_5425|M.vanbaalenii_PYR-1 --GDDNPVEHVVVVRRTGIDIAWTQGRDVLWEEVVPKASTEHTPEAFDSE
MSMEG_6179|M.smegmatis_MC2_155 ---DQPSVKNVLVVRRTGIDVKWTDGRDLWWDETVEQASTEHIPAAFDSE
MAB_0425c|M.abscessus_ATCC_199 LGGEPSSVEHVLVVRRTEIPVEWTEGRDLWWHETVDKADTTHTAEPFDSE
TH_0966|M.thermoresistible__bu ---NQPTVEHVLVVRRTGLDVPWTEGRDVWWHDAVDNASTEHTPDAFDSE
MLBr_00134|M.leprae_Br4923 GEALEPALAERLVEFFGGIPILDGIGSSEVGQTFVSNSVDDWRVGTLGKV
.: . :* : . . * : .:
Rv3667|M.tuberculosis_H37Rv HPLFLLYTSGTTGKPKGIMHTSGGYLT--QCCYTMRTIFDVKPDSDVFWC
Mb3691|M.bovis_AF2122/97 HPLFLLYTSGTTGKPKGIMHTSGGYLT--QCCYTMRTIFDVKPDSDVFWC
MMAR_5155|M.marinum_M QPLFLLYTSGTTGKPKGIVHTSGGYLT--QCCYTVHTIFDVKPETDVFWC
MUL_4241|M.ulcerans_Agy99 QPLFLLYTSGTTGKPKGIVHTSGGYLT--QCCYTVHTIFDVKPETDVFWC
MAV_0462|M.avium_104 QPLFLLYTSGTTGKPKGIVHTSGGYLT--QAAYTHYYVFDIKADTDVFWC
Mflv_1380|M.gilvum_PYR-GCK QPLFLLYTSGTTGKPKGIVHTSGGYLT--QTAYTHHNVFDLKPESDVYWC
Mvan_5425|M.vanbaalenii_PYR-1 HPLFLLYTSGTTGKPKGIMHTSGGYLT--QASYTHYNVFDIKPETDVYWC
MSMEG_6179|M.smegmatis_MC2_155 QPLFLLYTSGTTGKPKGIVHTSGGYLT--QSSYTHWNVFDVKPESDVYWC
MAB_0425c|M.abscessus_ATCC_199 HPLFLLYTSGTTGKPKGIVHTSGGFLT--QTSYTHFNIFDLKPETDVYWC
TH_0966|M.thermoresistible__bu HPLFLLYTSGTTGKPKGIVHTTGGFLT--QTAYSHHYVFDIKPETDVFWC
MLBr_00134|M.leprae_Br4923 LPPYEIRVVAPDGATAGSGIEGNLWVRGPSIAQSYWNRPDSLLENGDWLN
* : : . .. * . * . :: . . : * :.. :
Rv3667|M.tuberculosis_H37Rv TADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTI
Mb3691|M.bovis_AF2122/97 TADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTI
MMAR_5155|M.marinum_M TADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEKYGVTI
MUL_4241|M.ulcerans_Agy99 TADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEEYGVTI
MAV_0462|M.avium_104 TADIGWVTGHTYGVYGPLANGVTEVLYEGTPDTPTQHRHFEIIEKYGVTI
Mflv_1380|M.gilvum_PYR-GCK TADIGWVTGHSYIVYGPLANGATQVVYEGTPASPTEHRHFEIIEKYGVTI
Mvan_5425|M.vanbaalenii_PYR-1 TADIGWVTGHTYIVYGPLSNGATQVVYEGTPASPDEHRHFQVIEKYGVTI
MSMEG_6179|M.smegmatis_MC2_155 TADIGWVTGHTYIVYGPLSNGVTQVVYEGTPTSPTEHRHFEVIEKYGVTI
MAB_0425c|M.abscessus_ATCC_199 TADIGWVTGHTYIVYGPLSNGATQVVYEGTPTSPNEHRHFEIIEKYGVTI
TH_0966|M.thermoresistible__bu TADIGWVTGHSYIVFGPLANGASQVVYEGTPNSPDEHRHFQIIEKYGVTI
MLBr_00134|M.leprae_Br4923 TRDRVRIDGDGWVTYG--CRADDTEIVGGVNINP---REVERLIIEADAV
* * : *. : .:* ... : *. .* *..: : . ::
Rv3667|M.tuberculosis_H37Rv YYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIG
Mb3691|M.bovis_AF2122/97 YYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIG
MMAR_5155|M.marinum_M YYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDVVG
MUL_4241|M.ulcerans_Agy99 YYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDVVG
MAV_0462|M.avium_104 YYTAPTLIRTFMKWGREIPDAHDLSSLRLLGSVGEPINPEAWRWYRSVIG
Mflv_1380|M.gilvum_PYR-GCK YYTAPTLVRTFMRWGRQIPAEHDLSSLRLLGSVGEPINPEAWRWYRMAFG
Mvan_5425|M.vanbaalenii_PYR-1 YYTAPTLVRTFMKWGRQLPAEHDLSSLRLLGSVGEPINPEAWRWYRLAFG
MSMEG_6179|M.smegmatis_MC2_155 YYTAPTLIRTFMKLGHQIPASHDLSSLRLLGSVGEPINPEAWRWYREHIG
MAB_0425c|M.abscessus_ATCC_199 YYIAPTLVRTFMKWGREIPFAHDLSSLRLLGSVGEPINPEAWRWYREVIG
TH_0966|M.thermoresistible__bu YYTAPTLIRTFMKWGREIPDAHDLSSLRLLGSVGEPINPEAWRWYRKVIG
MLBr_00134|M.leprae_Br4923 AEAAVVGVREFTGASTLQAFLVPAVGAFIDESVMRDVHRRLLTQLTAFKV
* . :* * . . . : ** . :: .
Rv3667|M.tuberculosis_H37Rv GGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHG
Mb3691|M.bovis_AF2122/97 GGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHG
MMAR_5155|M.marinum_M AGHTPIVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDDHG
MUL_4241|M.ulcerans_Agy99 AGHTPIVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDDHG
MAV_0462|M.avium_104 ADRLPIVDTWWQTETGATMISPLPGVAAAKPGSAMRPLPGISARIVDDHG
Mflv_1380|M.gilvum_PYR-GCK KDKTPIVDTWWQTETGAIMISPLPGVTHCKPGSAMRALPGISAKVVDDDG
Mvan_5425|M.vanbaalenii_PYR-1 GDNTPVVDTWWQTETGGIMISPLPGVTHCKPGSAMRALPGISAKIVDDDG
MSMEG_6179|M.smegmatis_MC2_155 GGKTPIVDTWWQTETGAIMISPLPGVTAAKPGSAMTPLPGISAKIVDDEG
MAB_0425c|M.abscessus_ATCC_199 GNRTPIVDTWWQTETGSAMISPLPGVTETKPGSAMRAVPGISAKIVDDEG
TH_0966|M.thermoresistible__bu GDRTPVVDTWWQTETGAIMISPLPGVTAAKPGAAMAPLPGISAQIVDDDG
MLBr_00134|M.leprae_Br4923 PHRFAIIERLPRSTNGKLLRNVLRAQSPTKPIWELSLTESQSATKAQLDG
. .::: :: .* : . * . : ** : . ** .: .*
Rv3667|M.tuberculosis_H37Rv DPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGY
Mb3691|M.bovis_AF2122/97 DPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGY
MMAR_5155|M.marinum_M DPLAPETDEGTHVTGYLVLDQPWPSMLRGIWGDPARFHYAYWSKFEDKGY
MUL_4241|M.ulcerans_Agy99 DPLAPETDEGTHVTGYLVLDQPWPSMLRGIWGDPARFHYAYWSKFEDKGY
MAV_0462|M.avium_104 DQLVPGIHHGEHVTGYLVLDQPWPSMLRGIWGDPDRYVETYWSRFAEQGW
Mflv_1380|M.gilvum_PYR-GCK NELERSPDHGEHATGYLVLDQPWPAMLRGIWGDPERFKETYWSRFAEKGW
Mvan_5425|M.vanbaalenii_PYR-1 NELEPSPDYGEHVTGYLVLDKPWPAMLRGIWGDEERFRETYWSRFAEKGW
MSMEG_6179|M.smegmatis_MC2_155 NQLVPGADEAEHVTGYLVLDQPWPAMLRGIWGDPQRFKDTYWSRFAEQGW
MAB_0425c|M.abscessus_ATCC_199 NQLEPASGD-EPVTGYLVLDKPWPSMLRGIWGDPERFKETYWSRYAEQGW
TH_0966|M.thermoresistible__bu DRIPNSPEGGEPITGYLVLDQPWPAMLRGIWNDPERYRETYWQRFESKGW
MLBr_00134|M.leprae_Br4923 R---PASNAHAQAAVGHAAGATLKQRLSALQQERERLVVEAVCAEAVK-M
: . . . * .: : * :
Rv3667|M.tuberculosis_H37Rv YFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEA
Mb3691|M.bovis_AF2122/97 YFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEA
MMAR_5155|M.marinum_M YFAGDGARLDSDGAIWVLGRIDDVMNVSGHRISTAEVESALVGHPGVAEA
MUL_4241|M.ulcerans_Agy99 YFAGDGARLDSDGAIWVLGRIDDVMNVSGHRISTAEVESALVGHPGVAEA
MAV_0462|M.avium_104 YFAGDSAYYDRDGAIWVVGRIDDVMNVSGHRLSTAEVESALVGHHGVAEA
Mflv_1380|M.gilvum_PYR-GCK YFAGDGARIGSDGEIWVLGRIDDVMNISGHRISTAEVESALVGHSGVAEA
Mvan_5425|M.vanbaalenii_PYR-1 YFAGDGARYGTDGEIWVLGRIDDVMNISGHRISTAEVESALVGHSGVAEA
MSMEG_6179|M.smegmatis_MC2_155 YFAGDGARYDSDGHIWVLGRIDDVMNVSGHRISTAEVESALVGHAGVAEA
MAB_0425c|M.abscessus_ATCC_199 YFAGDGARYDSDGAIWVLGRIDDVMNISGHRISTAEVESALVGHDGVAEA
TH_0966|M.thermoresistible__bu YFAGDGARYDADGDIWVLGRIDDVMNVSGHRISTAEVESALVGHSGVAEA
MLBr_00134|M.leprae_Br4923 LGESDPGLINRDLAFSDLG-FDSQMTVTLCNRLAVVTGLRLPETVGWDYG
.* . . * : :* :*. *.:: . :. . * * .
Rv3667|M.tuberculosis_H37Rv AVVGVT----DETTTQAICAFVVLR-ANYAPHDRTAEELRTEVARVISPI
Mb3691|M.bovis_AF2122/97 AVVGVT----DETTTQAICAFVVLR-ANYAPHDRTAEELRTEVARVISPI
MMAR_5155|M.marinum_M AVVGVV----DDTTTQAICAFVVLR-GNYEQHDGTSDELRAEVAEAISPI
MUL_4241|M.ulcerans_Agy99 AVVGVV----DDTTTQAICAFVVLR-GNYEQHDGTSEELRAEVAEAISPI
MAV_0462|M.avium_104 AVVGAT----DATTGQAICAFVVLC-ADYQVHDGIVDELRAEVAREISPI
Mflv_1380|M.gilvum_PYR-GCK AVVGAT----DEHTGQAICAFVILKSSAHGGEENMIDELRAEVAKEISPI
Mvan_5425|M.vanbaalenii_PYR-1 AVVGAS----DEHTGQAICAFVILKSSAHGGEANMVDELRAEVAREISPI
MSMEG_6179|M.smegmatis_MC2_155 AVVGAS----DDTTGQAICAFVILKASAHGGPENMIEELRAEVAREISPI
MAB_0425c|M.abscessus_ATCC_199 AVVGAS----DETTGQAIVAFVILKASHTVEGDELVSHLKAQVSKEISPI
TH_0966|M.thermoresistible__bu AVVGAS----DPQTGQAICAFVILEADAK-DNDNMVEELRAQVAREISPI
MLBr_00134|M.leprae_Br4923 SISGLSRYLEAELSGVRSRPETPLSANSGAKGLSPIDEELKKVEEMVVAI
:: * : . . * .. :* . : .*
Rv3667|M.tuberculosis_H37Rv ARPRDVHVVPELPKTRSGKIMR---RLLRDVAENRELGDTSTLLDPTVFD
Mb3691|M.bovis_AF2122/97 ARPRDVHVVPELPKTRSGKIMR---RLLRDVAENRELGDTSTLLDPTVFD
MMAR_5155|M.marinum_M ARPREVHVVPELPKTRSGKIMR---RLLRDIAEKRELGDTSTLLDPTVFD
MUL_4241|M.ulcerans_Agy99 ARPREVHVVPELPKTRSGKIMR---RLLRDIAEKRELGDTSTLLDPTVFD
MAV_0462|M.avium_104 AKPREVHVVPELPKTRSGKIMR---RLLRDIAENRELGDTSTLLDPGVFD
Mflv_1380|M.gilvum_PYR-GCK AKPREIHVVPELPKTRSGKIMR---RLLRDVAEGRELGDTSTLVDPSVFE
Mvan_5425|M.vanbaalenii_PYR-1 AKPREIHVVPELPKTRSGKIMR---RLLRDVAEGRELGDTSTLLDPSVFE
MSMEG_6179|M.smegmatis_MC2_155 AKPREIHIVPELPKTRSGKIMR---RLLRDVAEGRELGDTSTLVDPSVFE
MAB_0425c|M.abscessus_ATCC_199 AKPREIHVVPELPKTRSGKIMR---RLLRDVAEGRELGDTSTLVDPSVFE
TH_0966|M.thermoresistible__bu AKPREIHVVPELPKTRSGKIMR---RLLRDVAEGRELGDTSTLVDPNVFE
MLBr_00134|M.leprae_Br4923 G-ASEKQRVADRLRALLGIIVDGEAGLSKRIQAASTPDEIFQLIDSELCE
. . : : *.: :: * *: * : : .: *:*. : :
Rv3667|M.tuberculosis_H37Rv AIR-AAK----
Mb3691|M.bovis_AF2122/97 AIR-AAK----
MMAR_5155|M.marinum_M AIRNAAK----
MUL_4241|M.ulcerans_Agy99 AIRNAAK----
MAV_0462|M.avium_104 AIR-AAK----
Mflv_1380|M.gilvum_PYR-GCK AIR-ASK----
Mvan_5425|M.vanbaalenii_PYR-1 AIR-ASK----
MSMEG_6179|M.smegmatis_MC2_155 AIR-ASK----
MAB_0425c|M.abscessus_ATCC_199 AIR-ASK----
TH_0966|M.thermoresistible__bu AIR-ATKGGPS
MLBr_00134|M.leprae_Br4923 -----------