For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_4241 (acs)

annotation: acetyl-CoA synthetase
coordinates: 4714374 - 4716356
length: 660

MKLNIGDTPVTATSAEEPSSYPPPAEFIEQANARAELYREAEEDRLAFWAKQADRLSWATPFGEVLDWSD
APFANWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYADLQAEVSKAANALTGLGLVAG
DRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTANTLHARIVDAQAKLLITSDGQFRRGHPAPLKDAA
DEAVSQPDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPQHTPEPFDAEQPLFLLYTSGTTGKPKG
IVHTSGGYLTQCCYTVHTIFDVKPETDVFWCTADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRH
FQIIEEYGVTIYYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDVVGAGHTPIVDT
WWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDDHGDPLAPETDEGTHVTGYLVLDQPWPSMLRG
IWGDPARFHYAYWSKFEDKGYYFAGDGARLDSDGAIWVLGRIDDVMNVSGHRISTAEVESALVGHPGVAE
AAVVGVVDDTTTQAICAFVVLRGNYEQHDGTSEELRAEVAEAISPIARPREVHVVPELPKTRSGKIMRRL
LRDIAEKRELGDTSTLLDPTVFDAIRNAAK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4241acs-100% (660)acetyl-CoA synthetase
M. ulcerans Agy99MUL_0229fadD141e-2726.06% (564) acyl-CoA synthetase
M. ulcerans Agy99MUL_3641mbtA2e-2624.32% (551) bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3691acs0.085.38% (650) acetyl-CoA synthetase
M. gilvum PYR-GCKMflv_1380-0.074.00% (650) acetyl-CoA synthetase
M. tuberculosis H37RvRv3667acs0.085.38% (650) acetyl-CoA synthetase
M. leprae Br4923MLBr_01051xclC7e-2931.41% (398) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_0425c-0.073.25% (658) Acetyl-CoA synthetase
M. marinum MMMAR_5155acs0.099.23% (651) acetyl-coenzyme A synthetase Acs
M. avium 104MAV_0462acsA0.081.20% (649) acetyl-CoA synthetase
M. smegmatis MC2 155MSMEG_6179-0.076.22% (656) acetyl-coenzyme A synthetase
M. thermoresistible (build 8)TH_0966acs0.075.43% (647) ACETYL-COENZYME A SYNTHETASE ACS (ACETATE--CoA LIGASE)
M. vanbaalenii PYR-1Mvan_5425-0.073.85% (654) acetyl-CoA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4241|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5155|M.marinum_M               --------------------------------------------------
Mb3691|M.bovis_AF2122/97            --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_0462|M.avium_104                --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155      MCCAIWSASRAPACSASQLSSSHAVRPSVVPDANPRAAPRYSPDLRIQCT
MAB_0425c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0966|M.thermoresistible__bu      --------------------------------------------------
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MUL_4241|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5155|M.marinum_M               --------------------------------------------------
Mb3691|M.bovis_AF2122/97            --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_0462|M.avium_104                --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155      SGTPRPCGSSPLAIVTSRETARATTPSAVPNGASVSNSPCATAASTGAGA
MAB_0425c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0966|M.thermoresistible__bu      --------------------------------------------------
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MUL_4241|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5155|M.marinum_M               --------------------------------------------------
Mb3691|M.bovis_AF2122/97            --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_0462|M.avium_104                --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155      LDPPVRSSISNSRRGPTSGSVRGRPRCSSSVRSAAASACSRASACIGARC
MAB_0425c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0966|M.thermoresistible__bu      --------------------------------------------------
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MUL_4241|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5155|M.marinum_M               --------------------------------------------------
Mb3691|M.bovis_AF2122/97            --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_0462|M.avium_104                --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155      HTVTNEVAPPSSASATRIAPAVTGSGSPSADSCTAPPSSTADARAPRSAD
MAB_0425c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0966|M.thermoresistible__bu      --------------------------------------------------
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MUL_4241|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5155|M.marinum_M               --------------------------------------------------
Mb3691|M.bovis_AF2122/97            --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_0462|M.avium_104                --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5425|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155      SAAVCGQPRRLTLCRCARPSASRASSQAAATPGSSNSGARGSGRSVITSH
MAB_0425c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0966|M.thermoresistible__bu      --------------------------------------------------
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MUL_4241|M.ulcerans_Agy99           ------------------------------MKLNIGDTPVT-ATSAEEPS
MMAR_5155|M.marinum_M               ---------------------------------------MT-ATSAEEPS
Mb3691|M.bovis_AF2122/97            ---------------------------------------MS-ESTPEVSS
Rv3667|M.tuberculosis_H37Rv         ---------------------------------------MS-ESTPEVSS
MAV_0462|M.avium_104                ---------------------------------------MT-ASNTANPP
Mflv_1380|M.gilvum_PYR-GCK          ---------------------------------------MT-ETHVDIPS
Mvan_5425|M.vanbaalenii_PYR-1       -----------------------------MQRLVTTLTTMT-ETQLDAIA
MSMEG_6179|M.smegmatis_MC2_155      ASRPLIASSPTVQRNQTTVHQQTCEGPTCVQRSVTRLTAMSNPSHAEVPS
MAB_0425c|M.abscessus_ATCC_199      ---------------------------------------MT-ETSIE-PD
TH_0966|M.thermoresistible__bu      ---------------------------------------MS-ETHTEAQS
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MUL_4241|M.ulcerans_Agy99           SYPPPAEFIEQANARAELYREAEEDRLAFWAKQADRLSWATPFGEVLDWS
MMAR_5155|M.marinum_M               SYPPPAEFIEQANARAELYREAEEDRLAFWAKQADRLSWATPFGEVLDWS
Mb3691|M.bovis_AF2122/97            SYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWS
Rv3667|M.tuberculosis_H37Rv         SYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWS
MAV_0462|M.avium_104                SYPPPPQFVEQANAGEQLYREAERDRLAFWAEQANRLSWATPFTEVLDWS
Mflv_1380|M.gilvum_PYR-GCK          SYPPDPGFAENANATEALYEQADADRLEFWAEQARRLAWETPFDEVLDWS
Mvan_5425|M.vanbaalenii_PYR-1       SYPPPPEFTESANATAELYDEAEADRLAFWAKQANRLSWQTPFTEVLDWS
MSMEG_6179|M.smegmatis_MC2_155      AYPPPADFAANANATGELYAEAEKDRLAFWEKQAKRLSWQTPFTDVLDWS
MAB_0425c|M.abscessus_ATCC_199      SYPPSPEFVATANATADLYQAAEEDRLGFWEQQAGRLHWDEPFGQVLDWS
TH_0966|M.thermoresistible__bu      VYPPPAEFAAQSNATADLYREAEADRLAFWARQAERLTWAKPFEQVLDWS
MLBr_01051|M.leprae_Br4923          ------------------------------------------------ML
                                                                                      

MUL_4241|M.ulcerans_Agy99           DAPFANWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYA
MMAR_5155|M.marinum_M               DAPFAKWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYA
Mb3691|M.bovis_AF2122/97            EAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYS
Rv3667|M.tuberculosis_H37Rv         GAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYS
MAV_0462|M.avium_104                RAPFAEWFADGTLNVAYNCVDRHVQAGHGDRVAIHWEGESPGDQRSLTYS
Mflv_1380|M.gilvum_PYR-GCK          EAPFAKWFVGGTLNVAYNCVDRHVEAGNGDRVAIHWVGEPVEHSRDITYA
Mvan_5425|M.vanbaalenii_PYR-1       DAPFAKWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWEGEPVGDARDITYA
MSMEG_6179|M.smegmatis_MC2_155      DAPFAKWFVGGKINVAYNCVDRHVEAGNGDRVAIHWEGEPVGDARSITYA
MAB_0425c|M.abscessus_ATCC_199      DAPFAKWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWEGEP-GDTRTITYA
TH_0966|M.thermoresistible__bu      EAPFAKWFVGGRLNVAYNCVDRHVEAGNGDRVAIYWEGEPVGDSRTLTYA
MLBr_01051|M.leprae_Br4923          LASLNPSVVTATDIADAVCVDGVVLSRSGLVGAATSVAERVGGAR-----
                                     *.:   .. .   .   ***  * :  *   *    .*     *     

MUL_4241|M.ulcerans_Agy99           DLQAEVSKAANALTGLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV
MMAR_5155|M.marinum_M               DLQAEVSKAANALTGLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV
Mb3691|M.bovis_AF2122/97            DLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV
Rv3667|M.tuberculosis_H37Rv         DLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV
MAV_0462|M.avium_104                ELYTQVCKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGVMHSV
Mflv_1380|M.gilvum_PYR-GCK          ELKDEVCRAANALTNLGLTAGDRVAIYMPMVPEAIIAMLACARLGAMHSV
Mvan_5425|M.vanbaalenii_PYR-1       QLKDEVCQAANAFAELGLKAGDRVAIYMPMVPEAIIAMLACARLGAMHSV
MSMEG_6179|M.smegmatis_MC2_155      ELKDEVCKAANALTDLGLVAGDRVAIYMPMIPEAIVAMLACARLGVMHSV
MAB_0425c|M.abscessus_ATCC_199      ELLAQVSQAANYLTELGLVSGDRVAIYMPMLPEAIVAMLACARLGLMHSV
TH_0966|M.thermoresistible__bu      QLKDEVSKAANALTRLGLRTGDRVAIYMPMIPEAIISMLACARLGVLHSV
MLBr_01051|M.leprae_Br4923          -------------------------------LVAVLATPTASTVLAITGC
                                                                     *:::  :.: :  : . 

MUL_4241|M.ulcerans_Agy99           VFGGFTANTLHARIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ---
MMAR_5155|M.marinum_M               VFGGFTANALHARIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ---
Mb3691|M.bovis_AF2122/97            VFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAI--
Rv3667|M.tuberculosis_H37Rv         VFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAI--
MAV_0462|M.avium_104                VFAGFTAKALQARIADAAAKLLITSDGQFRRGKPAPLKDAADEAVAD---
Mflv_1380|M.gilvum_PYR-GCK          VFAGFSASALKARIEDAQAKLVITTDGQYRRGSAVSLKTGVDEAIDGL--
Mvan_5425|M.vanbaalenii_PYR-1       VFAGFSASALKARIEDAQTKLVVTTDGQYRRGSAVALKTAVDEAIESL--
MSMEG_6179|M.smegmatis_MC2_155      VFAGFSASALRARIEDAEAKLVITSDGQYRRGKAASLKEAVDEAVA----
MAB_0425c|M.abscessus_ATCC_199      VFAGFSAAALRARIDDAQAKLVITSDGQWRRGTAAPLKSQVDEALGAAGP
TH_0966|M.thermoresistible__bu      VFAGFSSSALTARIQDAEAKLLITADGQYRRGNAVPLKTNADEAVQ----
MLBr_01051|M.leprae_Br4923          LIAGVPVVPVPADIGVVERRHMLTDSGAQAWLGPGPSADSAPDGLPHIP-
                                    ::.*..  .: * *  .  : ::* .*      . .    . :.:     

MUL_4241|M.ulcerans_Agy99           -------PDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPQHTPEP
MMAR_5155|M.marinum_M               -------PDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPEHTPEP
Mb3691|M.bovis_AF2122/97            -------PDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEP
Rv3667|M.tuberculosis_H37Rv         -------PDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEP
MAV_0462|M.avium_104                -------PDSPVEHVVVVRRTGIDVSWTDGRDLWWHDVVDAAAPEHTPEP
Mflv_1380|M.gilvum_PYR-GCK          ------GEDSPVEHVLVVRRTGIDTPWTPDRDLWWDETVPEADTEHTPEA
Mvan_5425|M.vanbaalenii_PYR-1       ------GDDNPVEHVVVVRRTGIDIAWTQGRDVLWEEVVPKASTEHTPEA
MSMEG_6179|M.smegmatis_MC2_155      -------DQPSVKNVLVVRRTGIDVKWTDGRDLWWDETVEQASTEHIPAA
MAB_0425c|M.abscessus_ATCC_199      ATSDLGGEPSSVEHVLVVRRTEIPVEWTEGRDLWWHETVDKADTTHTAEP
TH_0966|M.thermoresistible__bu      -------NQPTVEHVLVVRRTGLDVPWTEGRDVWWHDAVDNASTEHTPDA
MLBr_01051|M.leprae_Br4923          ------------------------------------VQLDARSWNRYPEP
                                                                          :      : . .

MUL_4241|M.ulcerans_Agy99           FDAEQPLFLLYTSGTTGKPKGIVHTSGGYLTQCCYTVHTIFDVKPETDVF
MMAR_5155|M.marinum_M               FDAEQPLFLLYTSGTTGKPKGIVHTSGGYLTQCCYTVHTIFDVKPETDVF
Mb3691|M.bovis_AF2122/97            FDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVF
Rv3667|M.tuberculosis_H37Rv         FDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVF
MAV_0462|M.avium_104                FPAEQPLFLLYTSGTTGKPKGIVHTSGGYLTQAAYTHYYVFDIKADTDVF
Mflv_1380|M.gilvum_PYR-GCK          FDSEQPLFLLYTSGTTGKPKGIVHTSGGYLTQTAYTHHNVFDLKPESDVY
Mvan_5425|M.vanbaalenii_PYR-1       FDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQASYTHYNVFDIKPETDVY
MSMEG_6179|M.smegmatis_MC2_155      FDSEQPLFLLYTSGTTGKPKGIVHTSGGYLTQSSYTHWNVFDVKPESDVY
MAB_0425c|M.abscessus_ATCC_199      FDSEHPLFLLYTSGTTGKPKGIVHTSGGFLTQTSYTHFNIFDLKPETDVY
TH_0966|M.thermoresistible__bu      FDSEHPLFLLYTSGTTGKPKGIVHTTGGFLTQTAYSHHYVFDIKPETDVF
MLBr_01051|M.leprae_Br4923          S-PDATAMVIYTSGTTGPPKGVLLSRR-AIAVDLDALAQAWQWTAD-DVL
                                      .: . :::******* ***:: :    ::    :    :: ..: ** 

MUL_4241|M.ulcerans_Agy99           WCTADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEEYGV
MMAR_5155|M.marinum_M               WCTADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEKYGV
Mb3691|M.bovis_AF2122/97            WCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGV
Rv3667|M.tuberculosis_H37Rv         WCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGV
MAV_0462|M.avium_104                WCTADIGWVTGHTYGVYGPLANGVTEVLYEGTPDTPTQHRHFEIIEKYGV
Mflv_1380|M.gilvum_PYR-GCK          WCTADIGWVTGHSYIVYGPLANGATQVVYEGTPASPTEHRHFEIIEKYGV
Mvan_5425|M.vanbaalenii_PYR-1       WCTADIGWVTGHTYIVYGPLSNGATQVVYEGTPASPDEHRHFQVIEKYGV
MSMEG_6179|M.smegmatis_MC2_155      WCTADIGWVTGHTYIVYGPLSNGVTQVVYEGTPTSPTEHRHFEVIEKYGV
MAB_0425c|M.abscessus_ATCC_199      WCTADIGWVTGHTYIVYGPLSNGATQVVYEGTPTSPNEHRHFEIIEKYGV
TH_0966|M.thermoresistible__bu      WCTADIGWVTGHSYIVFGPLANGASQVVYEGTPNSPDEHRHFQIIEKYGV
MLBr_01051|M.leprae_Br4923          VHGLPLFHVHGLVLGLLGSLRIGN-RFVHTGKPTP---TAYAQACSEAGG
                                         :  * *    : *.*  *  ..:: *.* .     : :  .: * 

MUL_4241|M.ulcerans_Agy99           TIYYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDV
MMAR_5155|M.marinum_M               TIYYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDV
Mb3691|M.bovis_AF2122/97            TIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDV
Rv3667|M.tuberculosis_H37Rv         TIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDV
MAV_0462|M.avium_104                TIYYTAPTLIRTFMKWGREIPDAHDLSSLRLLGSVGEPINPEAWRWYRSV
Mflv_1380|M.gilvum_PYR-GCK          TIYYTAPTLVRTFMRWGRQIPAEHDLSSLRLLGSVGEPINPEAWRWYRMA
Mvan_5425|M.vanbaalenii_PYR-1       TIYYTAPTLVRTFMKWGRQLPAEHDLSSLRLLGSVGEPINPEAWRWYRLA
MSMEG_6179|M.smegmatis_MC2_155      TIYYTAPTLIRTFMKLGHQIPASHDLSSLRLLGSVGEPINPEAWRWYREH
MAB_0425c|M.abscessus_ATCC_199      TIYYIAPTLVRTFMKWGREIPFAHDLSSLRLLGSVGEPINPEAWRWYREV
TH_0966|M.thermoresistible__bu      TIYYTAPTLIRTFMKWGREIPDAHDLSSLRLLGSVGEPINPEAWRWYRKV
MLBr_01051|M.leprae_Br4923          SLYFGVPTVWS---RLVADEAVARALRPARLLVSGSASLPVPVFDRLAHL
                                    ::*: .**:     :     .  : * . *** * . .:   .:      

MUL_4241|M.ulcerans_Agy99           VGAGHTPIVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDD
MMAR_5155|M.marinum_M               VGAGHTPIVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDD
Mb3691|M.bovis_AF2122/97            IGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDD
Rv3667|M.tuberculosis_H37Rv         IGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDD
MAV_0462|M.avium_104                IGADRLPIVDTWWQTETGATMISPLPGVAAAKPGSAMRPLPGISARIVDD
Mflv_1380|M.gilvum_PYR-GCK          FGKDKTPIVDTWWQTETGAIMISPLPGVTHCKPGSAMRALPGISAKVVDD
Mvan_5425|M.vanbaalenii_PYR-1       FGGDNTPVVDTWWQTETGGIMISPLPGVTHCKPGSAMRALPGISAKIVDD
MSMEG_6179|M.smegmatis_MC2_155      IGGGKTPIVDTWWQTETGAIMISPLPGVTAAKPGSAMTPLPGISAKIVDD
MAB_0425c|M.abscessus_ATCC_199      IGGNRTPIVDTWWQTETGSAMISPLPGVTETKPGSAMRAVPGISAKIVDD
TH_0966|M.thermoresistible__bu      IGGDRTPVVDTWWQTETGAIMISPLPGVTAAKPGAAMAPLPGISAQIVDD
MLBr_01051|M.leprae_Br4923          TG---HRPIERYGSTES--LITLSTLADGERRAGWVGLPLAGVQTRLVDE
                                     *      :: : .**:   :  .  .    :.* .  .:.*:.:::**:

MUL_4241|M.ulcerans_Agy99           HGDPLAPETDEGTHVTGYLVLDQPWPSMLRGIWGDPARFHYAYWSKFEDK
MMAR_5155|M.marinum_M               HGDPLAPETDEGTHVTGYLVLDQPWPSMLRGIWGDPARFHYAYWSKFEDK
Mb3691|M.bovis_AF2122/97            HGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDK
Rv3667|M.tuberculosis_H37Rv         HGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDK
MAV_0462|M.avium_104                HGDQLVPGIHHGEHVTGYLVLDQPWPSMLRGIWGDPDRYVETYWSRFAEQ
Mflv_1380|M.gilvum_PYR-GCK          DGNELERSPDHGEHATGYLVLDQPWPAMLRGIWGDPERFKETYWSRFAEK
Mvan_5425|M.vanbaalenii_PYR-1       DGNELEPSPDYGEHVTGYLVLDKPWPAMLRGIWGDEERFRETYWSRFAEK
MSMEG_6179|M.smegmatis_MC2_155      EGNQLVPGADEAEHVTGYLVLDQPWPAMLRGIWGDPQRFKDTYWSRFAEQ
MAB_0425c|M.abscessus_ATCC_199      EGNQLEPASGD-EPVTGYLVLDKPWPSMLRGIWGDPERFKETYWSRYAEQ
TH_0966|M.thermoresistible__bu      DGDRIPNSPEGGEPITGYLVLDQPWPAMLRGIWNDPERYRETYWQRFESK
MLBr_01051|M.leprae_Br4923          SGG---PVPYDGETVG---RLQVRSPTMFGGYLNRPE----ATAEAFDED
                                     *.                 *:   *:*: *  .       :  . : ..

MUL_4241|M.ulcerans_Agy99           GYYFAGDGARLDSDGAIWVLGR-IDDVMNVSGHRISTAEVESALVGHPGV
MMAR_5155|M.marinum_M               GYYFAGDGARLDSDGAIWVLGR-IDDVMNVSGHRISTAEVESALVGHPGV
Mb3691|M.bovis_AF2122/97            GYYFAGDGARIDPDGAIWVLGR-IDDVMNVSGHRISTAEVESALVAHSGV
Rv3667|M.tuberculosis_H37Rv         GYYFAGDGARIDPDGAIWVLGR-IDDVMNVSGHRISTAEVESALVAHSGV
MAV_0462|M.avium_104                GWYFAGDSAYYDRDGAIWVVGR-IDDVMNVSGHRLSTAEVESALVGHHGV
Mflv_1380|M.gilvum_PYR-GCK          GWYFAGDGARIGSDGEIWVLGR-IDDVMNISGHRISTAEVESALVGHSGV
Mvan_5425|M.vanbaalenii_PYR-1       GWYFAGDGARYGTDGEIWVLGR-IDDVMNISGHRISTAEVESALVGHSGV
MSMEG_6179|M.smegmatis_MC2_155      GWYFAGDGARYDSDGHIWVLGR-IDDVMNVSGHRISTAEVESALVGHAGV
MAB_0425c|M.abscessus_ATCC_199      GWYFAGDGARYDSDGAIWVLGR-IDDVMNISGHRISTAEVESALVGHDGV
TH_0966|M.thermoresistible__bu      GWYFAGDGARYDADGDIWVLGR-IDDVMNVSGHRISTAEVESALVGHSGV
MLBr_01051|M.leprae_Br4923          GWYRTGDVAVVDSGGMHRIVGRESVDLIKLGGYRIGAGEIEMALLGHPDV
                                    *:* :** *  . .*   ::**   *::::.*:*:.:.*:* **:.* .*

MUL_4241|M.ulcerans_Agy99           AEAAVVGVVDDTTTQAICAFVVLR-GNYEQHDGTSEELRAEVAEAISPIA
MMAR_5155|M.marinum_M               AEAAVVGVVDDTTTQAICAFVVLR-GNYEQHDGTSDELRAEVAEAISPIA
Mb3691|M.bovis_AF2122/97            AEAAVVGVTDETTTQAICAFVVLR-ANYAPHDRTAEELRTEVARVISPIA
Rv3667|M.tuberculosis_H37Rv         AEAAVVGVTDETTTQAICAFVVLR-ANYAPHDRTAEELRTEVARVISPIA
MAV_0462|M.avium_104                AEAAVVGATDATTGQAICAFVVLC-ADYQVHDGIVDELRAEVAREISPIA
Mflv_1380|M.gilvum_PYR-GCK          AEAAVVGATDEHTGQAICAFVILKSSAHGGEENMIDELRAEVAKEISPIA
Mvan_5425|M.vanbaalenii_PYR-1       AEAAVVGASDEHTGQAICAFVILKSSAHGGEANMVDELRAEVAREISPIA
MSMEG_6179|M.smegmatis_MC2_155      AEAAVVGASDDTTGQAICAFVILKASAHGGPENMIEELRAEVAREISPIA
MAB_0425c|M.abscessus_ATCC_199      AEAAVVGASDETTGQAIVAFVILKASHTVEGDELVSHLKAQVSKEISPIA
TH_0966|M.thermoresistible__bu      AEAAVVGASDPQTGQAICAFVILEADAK-DNDNMVEELRAQVAREISPIA
MLBr_01051|M.leprae_Br4923          REVAVVGLPDEDLGQRIVAFVVGA------EALDADELINYVAQQLSIHK
                                     *.****  *    * * ***:             ..*   *:. :*   

MUL_4241|M.ulcerans_Agy99           RPREVHVVPELPKTRSGKIMRRLLRDIAEKRELGDTSTLLDPTVFDAIRN
MMAR_5155|M.marinum_M               RPREVHVVPELPKTRSGKIMRRLLRDIAEKRELGDTSTLLDPTVFDAIRN
Mb3691|M.bovis_AF2122/97            RPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIR-
Rv3667|M.tuberculosis_H37Rv         RPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIR-
MAV_0462|M.avium_104                KPREVHVVPELPKTRSGKIMRRLLRDIAENRELGDTSTLLDPGVFDAIR-
Mflv_1380|M.gilvum_PYR-GCK          KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR-
Mvan_5425|M.vanbaalenii_PYR-1       KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLLDPSVFEAIR-
MSMEG_6179|M.smegmatis_MC2_155      KPREIHIVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR-
MAB_0425c|M.abscessus_ATCC_199      KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR-
TH_0966|M.thermoresistible__bu      KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPNVFEAIR-
MLBr_01051|M.leprae_Br4923          RPREVRFVDALPRNAMGKVLKKQLLFEG----------------------
                                    :**:::.*  **:.  **:::: *   .                      

MUL_4241|M.ulcerans_Agy99           AAK----
MMAR_5155|M.marinum_M               AAK----
Mb3691|M.bovis_AF2122/97            AAK----
Rv3667|M.tuberculosis_H37Rv         AAK----
MAV_0462|M.avium_104                AAK----
Mflv_1380|M.gilvum_PYR-GCK          ASK----
Mvan_5425|M.vanbaalenii_PYR-1       ASK----
MSMEG_6179|M.smegmatis_MC2_155      ASK----
MAB_0425c|M.abscessus_ATCC_199      ASK----
TH_0966|M.thermoresistible__bu      ATKGGPS
MLBr_01051|M.leprae_Br4923          -------