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MKLNIGDTPVTATSAEEPSSYPPPAEFIEQANARAELYREAEEDRLAFWAKQADRLSWATPFGEVLDWSD APFANWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYADLQAEVSKAANALTGLGLVAG DRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTANTLHARIVDAQAKLLITSDGQFRRGHPAPLKDAA DEAVSQPDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPQHTPEPFDAEQPLFLLYTSGTTGKPKG IVHTSGGYLTQCCYTVHTIFDVKPETDVFWCTADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRH FQIIEEYGVTIYYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDVVGAGHTPIVDT WWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDDHGDPLAPETDEGTHVTGYLVLDQPWPSMLRG IWGDPARFHYAYWSKFEDKGYYFAGDGARLDSDGAIWVLGRIDDVMNVSGHRISTAEVESALVGHPGVAE AAVVGVVDDTTTQAICAFVVLRGNYEQHDGTSEELRAEVAEAISPIARPREVHVVPELPKTRSGKIMRRL LRDIAEKRELGDTSTLLDPTVFDAIRNAAK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_4241 | acs | - | 100% (660) | acetyl-CoA synthetase |
M. ulcerans Agy99 | MUL_0229 | fadD14 | 1e-27 | 26.06% (564) | acyl-CoA synthetase |
M. ulcerans Agy99 | MUL_3641 | mbtA | 2e-26 | 24.32% (551) | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3691 | acs | 0.0 | 85.38% (650) | acetyl-CoA synthetase |
M. gilvum PYR-GCK | Mflv_1380 | - | 0.0 | 74.00% (650) | acetyl-CoA synthetase |
M. tuberculosis H37Rv | Rv3667 | acs | 0.0 | 85.38% (650) | acetyl-CoA synthetase |
M. leprae Br4923 | MLBr_01051 | xclC | 7e-29 | 31.41% (398) | acyl-CoA synthetase |
M. abscessus ATCC 19977 | MAB_0425c | - | 0.0 | 73.25% (658) | Acetyl-CoA synthetase |
M. marinum M | MMAR_5155 | acs | 0.0 | 99.23% (651) | acetyl-coenzyme A synthetase Acs |
M. avium 104 | MAV_0462 | acsA | 0.0 | 81.20% (649) | acetyl-CoA synthetase |
M. smegmatis MC2 155 | MSMEG_6179 | - | 0.0 | 76.22% (656) | acetyl-coenzyme A synthetase |
M. thermoresistible (build 8) | TH_0966 | acs | 0.0 | 75.43% (647) | ACETYL-COENZYME A SYNTHETASE ACS (ACETATE--CoA LIGASE) |
M. vanbaalenii PYR-1 | Mvan_5425 | - | 0.0 | 73.85% (654) | acetyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment MUL_4241|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5155|M.marinum_M -------------------------------------------------- Mb3691|M.bovis_AF2122/97 -------------------------------------------------- Rv3667|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0462|M.avium_104 -------------------------------------------------- Mflv_1380|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5425|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6179|M.smegmatis_MC2_155 MCCAIWSASRAPACSASQLSSSHAVRPSVVPDANPRAAPRYSPDLRIQCT MAB_0425c|M.abscessus_ATCC_199 -------------------------------------------------- TH_0966|M.thermoresistible__bu -------------------------------------------------- MLBr_01051|M.leprae_Br4923 -------------------------------------------------- MUL_4241|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5155|M.marinum_M -------------------------------------------------- Mb3691|M.bovis_AF2122/97 -------------------------------------------------- Rv3667|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0462|M.avium_104 -------------------------------------------------- Mflv_1380|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5425|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6179|M.smegmatis_MC2_155 SGTPRPCGSSPLAIVTSRETARATTPSAVPNGASVSNSPCATAASTGAGA MAB_0425c|M.abscessus_ATCC_199 -------------------------------------------------- TH_0966|M.thermoresistible__bu -------------------------------------------------- MLBr_01051|M.leprae_Br4923 -------------------------------------------------- MUL_4241|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5155|M.marinum_M -------------------------------------------------- Mb3691|M.bovis_AF2122/97 -------------------------------------------------- Rv3667|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0462|M.avium_104 -------------------------------------------------- Mflv_1380|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5425|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6179|M.smegmatis_MC2_155 LDPPVRSSISNSRRGPTSGSVRGRPRCSSSVRSAAASACSRASACIGARC MAB_0425c|M.abscessus_ATCC_199 -------------------------------------------------- TH_0966|M.thermoresistible__bu -------------------------------------------------- MLBr_01051|M.leprae_Br4923 -------------------------------------------------- MUL_4241|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5155|M.marinum_M -------------------------------------------------- Mb3691|M.bovis_AF2122/97 -------------------------------------------------- Rv3667|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0462|M.avium_104 -------------------------------------------------- Mflv_1380|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5425|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6179|M.smegmatis_MC2_155 HTVTNEVAPPSSASATRIAPAVTGSGSPSADSCTAPPSSTADARAPRSAD MAB_0425c|M.abscessus_ATCC_199 -------------------------------------------------- TH_0966|M.thermoresistible__bu -------------------------------------------------- MLBr_01051|M.leprae_Br4923 -------------------------------------------------- MUL_4241|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5155|M.marinum_M -------------------------------------------------- Mb3691|M.bovis_AF2122/97 -------------------------------------------------- Rv3667|M.tuberculosis_H37Rv -------------------------------------------------- MAV_0462|M.avium_104 -------------------------------------------------- Mflv_1380|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5425|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6179|M.smegmatis_MC2_155 SAAVCGQPRRLTLCRCARPSASRASSQAAATPGSSNSGARGSGRSVITSH MAB_0425c|M.abscessus_ATCC_199 -------------------------------------------------- TH_0966|M.thermoresistible__bu -------------------------------------------------- MLBr_01051|M.leprae_Br4923 -------------------------------------------------- MUL_4241|M.ulcerans_Agy99 ------------------------------MKLNIGDTPVT-ATSAEEPS MMAR_5155|M.marinum_M ---------------------------------------MT-ATSAEEPS Mb3691|M.bovis_AF2122/97 ---------------------------------------MS-ESTPEVSS Rv3667|M.tuberculosis_H37Rv ---------------------------------------MS-ESTPEVSS MAV_0462|M.avium_104 ---------------------------------------MT-ASNTANPP Mflv_1380|M.gilvum_PYR-GCK ---------------------------------------MT-ETHVDIPS Mvan_5425|M.vanbaalenii_PYR-1 -----------------------------MQRLVTTLTTMT-ETQLDAIA MSMEG_6179|M.smegmatis_MC2_155 ASRPLIASSPTVQRNQTTVHQQTCEGPTCVQRSVTRLTAMSNPSHAEVPS MAB_0425c|M.abscessus_ATCC_199 ---------------------------------------MT-ETSIE-PD TH_0966|M.thermoresistible__bu ---------------------------------------MS-ETHTEAQS MLBr_01051|M.leprae_Br4923 -------------------------------------------------- MUL_4241|M.ulcerans_Agy99 SYPPPAEFIEQANARAELYREAEEDRLAFWAKQADRLSWATPFGEVLDWS MMAR_5155|M.marinum_M SYPPPAEFIEQANARAELYREAEEDRLAFWAKQADRLSWATPFGEVLDWS Mb3691|M.bovis_AF2122/97 SYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWS Rv3667|M.tuberculosis_H37Rv SYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWS MAV_0462|M.avium_104 SYPPPPQFVEQANAGEQLYREAERDRLAFWAEQANRLSWATPFTEVLDWS Mflv_1380|M.gilvum_PYR-GCK SYPPDPGFAENANATEALYEQADADRLEFWAEQARRLAWETPFDEVLDWS Mvan_5425|M.vanbaalenii_PYR-1 SYPPPPEFTESANATAELYDEAEADRLAFWAKQANRLSWQTPFTEVLDWS MSMEG_6179|M.smegmatis_MC2_155 AYPPPADFAANANATGELYAEAEKDRLAFWEKQAKRLSWQTPFTDVLDWS MAB_0425c|M.abscessus_ATCC_199 SYPPSPEFVATANATADLYQAAEEDRLGFWEQQAGRLHWDEPFGQVLDWS TH_0966|M.thermoresistible__bu VYPPPAEFAAQSNATADLYREAEADRLAFWARQAERLTWAKPFEQVLDWS MLBr_01051|M.leprae_Br4923 ------------------------------------------------ML MUL_4241|M.ulcerans_Agy99 DAPFANWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYA MMAR_5155|M.marinum_M DAPFAKWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYA Mb3691|M.bovis_AF2122/97 EAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYS Rv3667|M.tuberculosis_H37Rv GAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYS MAV_0462|M.avium_104 RAPFAEWFADGTLNVAYNCVDRHVQAGHGDRVAIHWEGESPGDQRSLTYS Mflv_1380|M.gilvum_PYR-GCK EAPFAKWFVGGTLNVAYNCVDRHVEAGNGDRVAIHWVGEPVEHSRDITYA Mvan_5425|M.vanbaalenii_PYR-1 DAPFAKWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWEGEPVGDARDITYA MSMEG_6179|M.smegmatis_MC2_155 DAPFAKWFVGGKINVAYNCVDRHVEAGNGDRVAIHWEGEPVGDARSITYA MAB_0425c|M.abscessus_ATCC_199 DAPFAKWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWEGEP-GDTRTITYA TH_0966|M.thermoresistible__bu EAPFAKWFVGGRLNVAYNCVDRHVEAGNGDRVAIYWEGEPVGDSRTLTYA MLBr_01051|M.leprae_Br4923 LASLNPSVVTATDIADAVCVDGVVLSRSGLVGAATSVAERVGGAR----- *.: .. . . *** * : * * .* * MUL_4241|M.ulcerans_Agy99 DLQAEVSKAANALTGLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV MMAR_5155|M.marinum_M DLQAEVSKAANALTGLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV Mb3691|M.bovis_AF2122/97 DLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV Rv3667|M.tuberculosis_H37Rv DLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSV MAV_0462|M.avium_104 ELYTQVCKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGVMHSV Mflv_1380|M.gilvum_PYR-GCK ELKDEVCRAANALTNLGLTAGDRVAIYMPMVPEAIIAMLACARLGAMHSV Mvan_5425|M.vanbaalenii_PYR-1 QLKDEVCQAANAFAELGLKAGDRVAIYMPMVPEAIIAMLACARLGAMHSV MSMEG_6179|M.smegmatis_MC2_155 ELKDEVCKAANALTDLGLVAGDRVAIYMPMIPEAIVAMLACARLGVMHSV MAB_0425c|M.abscessus_ATCC_199 ELLAQVSQAANYLTELGLVSGDRVAIYMPMLPEAIVAMLACARLGLMHSV TH_0966|M.thermoresistible__bu QLKDEVSKAANALTRLGLRTGDRVAIYMPMIPEAIISMLACARLGVLHSV MLBr_01051|M.leprae_Br4923 -------------------------------LVAVLATPTASTVLAITGC *::: :.: : : . MUL_4241|M.ulcerans_Agy99 VFGGFTANTLHARIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ--- MMAR_5155|M.marinum_M VFGGFTANALHARIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ--- Mb3691|M.bovis_AF2122/97 VFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAI-- Rv3667|M.tuberculosis_H37Rv VFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAI-- MAV_0462|M.avium_104 VFAGFTAKALQARIADAAAKLLITSDGQFRRGKPAPLKDAADEAVAD--- Mflv_1380|M.gilvum_PYR-GCK VFAGFSASALKARIEDAQAKLVITTDGQYRRGSAVSLKTGVDEAIDGL-- Mvan_5425|M.vanbaalenii_PYR-1 VFAGFSASALKARIEDAQTKLVVTTDGQYRRGSAVALKTAVDEAIESL-- MSMEG_6179|M.smegmatis_MC2_155 VFAGFSASALRARIEDAEAKLVITSDGQYRRGKAASLKEAVDEAVA---- MAB_0425c|M.abscessus_ATCC_199 VFAGFSAAALRARIDDAQAKLVITSDGQWRRGTAAPLKSQVDEALGAAGP TH_0966|M.thermoresistible__bu VFAGFSSSALTARIQDAEAKLLITADGQYRRGNAVPLKTNADEAVQ---- MLBr_01051|M.leprae_Br4923 LIAGVPVVPVPADIGVVERRHMLTDSGAQAWLGPGPSADSAPDGLPHIP- ::.*.. .: * * . : ::* .* . . . :.: MUL_4241|M.ulcerans_Agy99 -------PDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPQHTPEP MMAR_5155|M.marinum_M -------PDSPVEHVLVVRRTGIDVSWNDERDLWWHDVVDSASPEHTPEP Mb3691|M.bovis_AF2122/97 -------PDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEP Rv3667|M.tuberculosis_H37Rv -------PDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEP MAV_0462|M.avium_104 -------PDSPVEHVVVVRRTGIDVSWTDGRDLWWHDVVDAAAPEHTPEP Mflv_1380|M.gilvum_PYR-GCK ------GEDSPVEHVLVVRRTGIDTPWTPDRDLWWDETVPEADTEHTPEA Mvan_5425|M.vanbaalenii_PYR-1 ------GDDNPVEHVVVVRRTGIDIAWTQGRDVLWEEVVPKASTEHTPEA MSMEG_6179|M.smegmatis_MC2_155 -------DQPSVKNVLVVRRTGIDVKWTDGRDLWWDETVEQASTEHIPAA MAB_0425c|M.abscessus_ATCC_199 ATSDLGGEPSSVEHVLVVRRTEIPVEWTEGRDLWWHETVDKADTTHTAEP TH_0966|M.thermoresistible__bu -------NQPTVEHVLVVRRTGLDVPWTEGRDVWWHDAVDNASTEHTPDA MLBr_01051|M.leprae_Br4923 ------------------------------------VQLDARSWNRYPEP : : . . MUL_4241|M.ulcerans_Agy99 FDAEQPLFLLYTSGTTGKPKGIVHTSGGYLTQCCYTVHTIFDVKPETDVF MMAR_5155|M.marinum_M FDAEQPLFLLYTSGTTGKPKGIVHTSGGYLTQCCYTVHTIFDVKPETDVF Mb3691|M.bovis_AF2122/97 FDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVF Rv3667|M.tuberculosis_H37Rv FDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVF MAV_0462|M.avium_104 FPAEQPLFLLYTSGTTGKPKGIVHTSGGYLTQAAYTHYYVFDIKADTDVF Mflv_1380|M.gilvum_PYR-GCK FDSEQPLFLLYTSGTTGKPKGIVHTSGGYLTQTAYTHHNVFDLKPESDVY Mvan_5425|M.vanbaalenii_PYR-1 FDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQASYTHYNVFDIKPETDVY MSMEG_6179|M.smegmatis_MC2_155 FDSEQPLFLLYTSGTTGKPKGIVHTSGGYLTQSSYTHWNVFDVKPESDVY MAB_0425c|M.abscessus_ATCC_199 FDSEHPLFLLYTSGTTGKPKGIVHTSGGFLTQTSYTHFNIFDLKPETDVY TH_0966|M.thermoresistible__bu FDSEHPLFLLYTSGTTGKPKGIVHTTGGFLTQTAYSHHYVFDIKPETDVF MLBr_01051|M.leprae_Br4923 S-PDATAMVIYTSGTTGPPKGVLLSRR-AIAVDLDALAQAWQWTAD-DVL .: . :::******* ***:: : :: : :: ..: ** MUL_4241|M.ulcerans_Agy99 WCTADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEEYGV MMAR_5155|M.marinum_M WCTADIGWVTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEKYGV Mb3691|M.bovis_AF2122/97 WCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGV Rv3667|M.tuberculosis_H37Rv WCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGV MAV_0462|M.avium_104 WCTADIGWVTGHTYGVYGPLANGVTEVLYEGTPDTPTQHRHFEIIEKYGV Mflv_1380|M.gilvum_PYR-GCK WCTADIGWVTGHSYIVYGPLANGATQVVYEGTPASPTEHRHFEIIEKYGV Mvan_5425|M.vanbaalenii_PYR-1 WCTADIGWVTGHTYIVYGPLSNGATQVVYEGTPASPDEHRHFQVIEKYGV MSMEG_6179|M.smegmatis_MC2_155 WCTADIGWVTGHTYIVYGPLSNGVTQVVYEGTPTSPTEHRHFEVIEKYGV MAB_0425c|M.abscessus_ATCC_199 WCTADIGWVTGHTYIVYGPLSNGATQVVYEGTPTSPNEHRHFEIIEKYGV TH_0966|M.thermoresistible__bu WCTADIGWVTGHSYIVFGPLANGASQVVYEGTPNSPDEHRHFQIIEKYGV MLBr_01051|M.leprae_Br4923 VHGLPLFHVHGLVLGLLGSLRIGN-RFVHTGKPTP---TAYAQACSEAGG : * * : *.* * ..:: *.* . : : .: * MUL_4241|M.ulcerans_Agy99 TIYYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDV MMAR_5155|M.marinum_M TIYYTAPTLIRTFMKWGRAIPDAHDLSSLRLLGSVGEPINPEAWRWYRDV Mb3691|M.bovis_AF2122/97 TIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDV Rv3667|M.tuberculosis_H37Rv TIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDV MAV_0462|M.avium_104 TIYYTAPTLIRTFMKWGREIPDAHDLSSLRLLGSVGEPINPEAWRWYRSV Mflv_1380|M.gilvum_PYR-GCK TIYYTAPTLVRTFMRWGRQIPAEHDLSSLRLLGSVGEPINPEAWRWYRMA Mvan_5425|M.vanbaalenii_PYR-1 TIYYTAPTLVRTFMKWGRQLPAEHDLSSLRLLGSVGEPINPEAWRWYRLA MSMEG_6179|M.smegmatis_MC2_155 TIYYTAPTLIRTFMKLGHQIPASHDLSSLRLLGSVGEPINPEAWRWYREH MAB_0425c|M.abscessus_ATCC_199 TIYYIAPTLVRTFMKWGREIPFAHDLSSLRLLGSVGEPINPEAWRWYREV TH_0966|M.thermoresistible__bu TIYYTAPTLIRTFMKWGREIPDAHDLSSLRLLGSVGEPINPEAWRWYRKV MLBr_01051|M.leprae_Br4923 SLYFGVPTVWS---RLVADEAVARALRPARLLVSGSASLPVPVFDRLAHL ::*: .**: : . : * . *** * . .: .: MUL_4241|M.ulcerans_Agy99 VGAGHTPIVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDD MMAR_5155|M.marinum_M VGAGHTPIVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDD Mb3691|M.bovis_AF2122/97 IGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDD Rv3667|M.tuberculosis_H37Rv IGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDD MAV_0462|M.avium_104 IGADRLPIVDTWWQTETGATMISPLPGVAAAKPGSAMRPLPGISARIVDD Mflv_1380|M.gilvum_PYR-GCK FGKDKTPIVDTWWQTETGAIMISPLPGVTHCKPGSAMRALPGISAKVVDD Mvan_5425|M.vanbaalenii_PYR-1 FGGDNTPVVDTWWQTETGGIMISPLPGVTHCKPGSAMRALPGISAKIVDD MSMEG_6179|M.smegmatis_MC2_155 IGGGKTPIVDTWWQTETGAIMISPLPGVTAAKPGSAMTPLPGISAKIVDD MAB_0425c|M.abscessus_ATCC_199 IGGNRTPIVDTWWQTETGSAMISPLPGVTETKPGSAMRAVPGISAKIVDD TH_0966|M.thermoresistible__bu IGGDRTPVVDTWWQTETGAIMISPLPGVTAAKPGAAMAPLPGISAQIVDD MLBr_01051|M.leprae_Br4923 TG---HRPIERYGSTES--LITLSTLADGERRAGWVGLPLAGVQTRLVDE * :: : .**: : . . :.* . .:.*:.:::**: MUL_4241|M.ulcerans_Agy99 HGDPLAPETDEGTHVTGYLVLDQPWPSMLRGIWGDPARFHYAYWSKFEDK MMAR_5155|M.marinum_M HGDPLAPETDEGTHVTGYLVLDQPWPSMLRGIWGDPARFHYAYWSKFEDK Mb3691|M.bovis_AF2122/97 HGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDK Rv3667|M.tuberculosis_H37Rv HGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDK MAV_0462|M.avium_104 HGDQLVPGIHHGEHVTGYLVLDQPWPSMLRGIWGDPDRYVETYWSRFAEQ Mflv_1380|M.gilvum_PYR-GCK DGNELERSPDHGEHATGYLVLDQPWPAMLRGIWGDPERFKETYWSRFAEK Mvan_5425|M.vanbaalenii_PYR-1 DGNELEPSPDYGEHVTGYLVLDKPWPAMLRGIWGDEERFRETYWSRFAEK MSMEG_6179|M.smegmatis_MC2_155 EGNQLVPGADEAEHVTGYLVLDQPWPAMLRGIWGDPQRFKDTYWSRFAEQ MAB_0425c|M.abscessus_ATCC_199 EGNQLEPASGD-EPVTGYLVLDKPWPSMLRGIWGDPERFKETYWSRYAEQ TH_0966|M.thermoresistible__bu DGDRIPNSPEGGEPITGYLVLDQPWPAMLRGIWNDPERYRETYWQRFESK MLBr_01051|M.leprae_Br4923 SGG---PVPYDGETVG---RLQVRSPTMFGGYLNRPE----ATAEAFDED *. *: *:*: * . : . : .. MUL_4241|M.ulcerans_Agy99 GYYFAGDGARLDSDGAIWVLGR-IDDVMNVSGHRISTAEVESALVGHPGV MMAR_5155|M.marinum_M GYYFAGDGARLDSDGAIWVLGR-IDDVMNVSGHRISTAEVESALVGHPGV Mb3691|M.bovis_AF2122/97 GYYFAGDGARIDPDGAIWVLGR-IDDVMNVSGHRISTAEVESALVAHSGV Rv3667|M.tuberculosis_H37Rv GYYFAGDGARIDPDGAIWVLGR-IDDVMNVSGHRISTAEVESALVAHSGV MAV_0462|M.avium_104 GWYFAGDSAYYDRDGAIWVVGR-IDDVMNVSGHRLSTAEVESALVGHHGV Mflv_1380|M.gilvum_PYR-GCK GWYFAGDGARIGSDGEIWVLGR-IDDVMNISGHRISTAEVESALVGHSGV Mvan_5425|M.vanbaalenii_PYR-1 GWYFAGDGARYGTDGEIWVLGR-IDDVMNISGHRISTAEVESALVGHSGV MSMEG_6179|M.smegmatis_MC2_155 GWYFAGDGARYDSDGHIWVLGR-IDDVMNVSGHRISTAEVESALVGHAGV MAB_0425c|M.abscessus_ATCC_199 GWYFAGDGARYDSDGAIWVLGR-IDDVMNISGHRISTAEVESALVGHDGV TH_0966|M.thermoresistible__bu GWYFAGDGARYDADGDIWVLGR-IDDVMNVSGHRISTAEVESALVGHSGV MLBr_01051|M.leprae_Br4923 GWYRTGDVAVVDSGGMHRIVGRESVDLIKLGGYRIGAGEIEMALLGHPDV *:* :** * . .* ::** *::::.*:*:.:.*:* **:.* .* MUL_4241|M.ulcerans_Agy99 AEAAVVGVVDDTTTQAICAFVVLR-GNYEQHDGTSEELRAEVAEAISPIA MMAR_5155|M.marinum_M AEAAVVGVVDDTTTQAICAFVVLR-GNYEQHDGTSDELRAEVAEAISPIA Mb3691|M.bovis_AF2122/97 AEAAVVGVTDETTTQAICAFVVLR-ANYAPHDRTAEELRTEVARVISPIA Rv3667|M.tuberculosis_H37Rv AEAAVVGVTDETTTQAICAFVVLR-ANYAPHDRTAEELRTEVARVISPIA MAV_0462|M.avium_104 AEAAVVGATDATTGQAICAFVVLC-ADYQVHDGIVDELRAEVAREISPIA Mflv_1380|M.gilvum_PYR-GCK AEAAVVGATDEHTGQAICAFVILKSSAHGGEENMIDELRAEVAKEISPIA Mvan_5425|M.vanbaalenii_PYR-1 AEAAVVGASDEHTGQAICAFVILKSSAHGGEANMVDELRAEVAREISPIA MSMEG_6179|M.smegmatis_MC2_155 AEAAVVGASDDTTGQAICAFVILKASAHGGPENMIEELRAEVAREISPIA MAB_0425c|M.abscessus_ATCC_199 AEAAVVGASDETTGQAIVAFVILKASHTVEGDELVSHLKAQVSKEISPIA TH_0966|M.thermoresistible__bu AEAAVVGASDPQTGQAICAFVILEADAK-DNDNMVEELRAQVAREISPIA MLBr_01051|M.leprae_Br4923 REVAVVGLPDEDLGQRIVAFVVGA------EALDADELINYVAQQLSIHK *.**** * * * ***: ..* *:. :* MUL_4241|M.ulcerans_Agy99 RPREVHVVPELPKTRSGKIMRRLLRDIAEKRELGDTSTLLDPTVFDAIRN MMAR_5155|M.marinum_M RPREVHVVPELPKTRSGKIMRRLLRDIAEKRELGDTSTLLDPTVFDAIRN Mb3691|M.bovis_AF2122/97 RPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIR- Rv3667|M.tuberculosis_H37Rv RPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIR- MAV_0462|M.avium_104 KPREVHVVPELPKTRSGKIMRRLLRDIAENRELGDTSTLLDPGVFDAIR- Mflv_1380|M.gilvum_PYR-GCK KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR- Mvan_5425|M.vanbaalenii_PYR-1 KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLLDPSVFEAIR- MSMEG_6179|M.smegmatis_MC2_155 KPREIHIVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR- MAB_0425c|M.abscessus_ATCC_199 KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR- TH_0966|M.thermoresistible__bu KPREIHVVPELPKTRSGKIMRRLLRDVAEGRELGDTSTLVDPNVFEAIR- MLBr_01051|M.leprae_Br4923 RPREVRFVDALPRNAMGKVLKKQLLFEG---------------------- :**:::.* **:. **:::: * . MUL_4241|M.ulcerans_Agy99 AAK---- MMAR_5155|M.marinum_M AAK---- Mb3691|M.bovis_AF2122/97 AAK---- Rv3667|M.tuberculosis_H37Rv AAK---- MAV_0462|M.avium_104 AAK---- Mflv_1380|M.gilvum_PYR-GCK ASK---- Mvan_5425|M.vanbaalenii_PYR-1 ASK---- MSMEG_6179|M.smegmatis_MC2_155 ASK---- MAB_0425c|M.abscessus_ATCC_199 ASK---- TH_0966|M.thermoresistible__bu ATKGGPS MLBr_01051|M.leprae_Br4923 -------