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M. tuberculosis H37Rv Rv3665c (dppB)

annotation: PROBABLE DIPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DPPB
coordinates: 4104531 - 4105457
length: 308

GWYVARRVAVMVPVFLGATLLIYGMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLG
GILHGDLGRAYSGLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLRQGGIFDSAVLVTGLVIIA
IPIFVLGFLAQFLFGVQLEIAPVTVGERASVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADYVRTAT
AKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFNIHGVGGVLYQAVTRQETPTVVSIVT
VLVLIYLITNLLVDLLYAALDPRIRYG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3665cdppB-100% (308)PROBABLE DIPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DPPB
M. tuberculosis H37RvRv1283coppB1e-3429.91% (321) oligopeptide-transport integral membrane protein ABC
M. tuberculosis H37RvRv3664cdppC9e-0725.91% (220) peptide ABC transporter transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3689cdppB1e-170100.00% (308) peptide ABC transporter transmembrane protein
M. gilvum PYR-GCKMflv_2760-3e-5036.62% (314) binding-protein-dependent transport systems inner membrane
M. leprae Br4923MLBr_01124-7e-3630.22% (321) putative binding-protein dependent transport protein
M. abscessus ATCC 19977MAB_0427-2e-9152.30% (304) peptide ABC transporter transmembrane protein
M. marinum MMMAR_5153dppB1e-15689.29% (308) dipeptide-transport integral membrane protein ABC
M. avium 104MAV_0465dppB1e-15689.94% (308) ABC transporter, permease protein DppB
M. smegmatis MC2 155MSMEG_6866-2e-5339.10% (312) dipeptide transport system permease protein DppB
M. thermoresistible (build 8)TH_2645-5e-5139.74% (312) PUTATIVE binding-protein-dependent transport systems inner
M. ulcerans Agy99MUL_4239dppB1e-15588.96% (308) dipeptide-transport integral membrane protein ABC
M. vanbaalenii PYR-1Mvan_3774-7e-5337.06% (313) binding-protein-dependent transport systems inner membrane

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2760|M.gilvum_PYR-GCK          -----------------MP-------ILRFVARRLLYSAVVMFGVLLVVF
Mvan_3774|M.vanbaalenii_PYR-1       -------------MSTAMP-------VLRFVARRLLFSAVVMIGVLVVVF
TH_2645|M.thermoresistible__bu      ------------MRFVTHP-------IARFLGRRLLYSLAVLFGVLVVVF
MSMEG_6866|M.smegmatis_MC2_155      MTDLLAGPAPIRAAAQRHPGGTRALNMGRVVLGKVASALIVLFVVATVAF
Rv3665c|M.tuberculosis_H37Rv        --------------------------MGWYVARRVAVMVPVFLGATLLIY
Mb3689c|M.bovis_AF2122/97           --------------------------MGWYVARRVAVMVPVFLGATLLIY
MAV_0465|M.avium_104                --------------------------MGWYIARRIAVMVPVFLGATLLIY
MMAR_5153|M.marinum_M               --------------------------MVWYVARRILAMVPVFLGATLLIY
MUL_4239|M.ulcerans_Agy99           --------------------------MVWYVARRILAMVPVFLGATLLIY
MAB_0427|M.abscessus_ATCC_1997      MTTVLG-----NVRQFWQSAG-----LFRYIAKRLLLAIPVLIGTSLLIY
MLBr_01124|M.leprae_Br4923          --------------------------MMRFLARRLLNYVVLLALASFLTY
                                                              :   :  ::     ::  .  : :

Mflv_2760|M.gilvum_PYR-GCK          ALVHLVPGDPVRIALGTR-YTPEAYEALRAASGLDRPLVSQFFGYIGSAL
Mvan_3774|M.vanbaalenii_PYR-1       ALVHLVPGDPVRIALGTR-YTPEAYEALRAASGLDRPIVSQFFGYLGSAL
TH_2645|M.thermoresistible__bu      GLMQLVPGDPVRIALGTR-YTPEAYQALRSASGLDRPILEQFVGYLTSAV
MSMEG_6866|M.smegmatis_MC2_155      LLVRMS-GDPLALLLPPD-ATQQQVEQLAAELGLDQPLLVQYLHYLSGML
Rv3665c|M.tuberculosis_H37Rv        GMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLGGIL
Mb3689c|M.bovis_AF2122/97           GMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLGGIL
MAV_0465|M.avium_104                AMVFLLPGDPVAAIAGDRPLTPAVAAALRARYHLDDPFLVQYLRYLGGVL
MMAR_5153|M.marinum_M               GMVFLLPGDPLAAIAGDRPLTPAVAQQLRARYHLDDPFLVQYAHYLGGVL
MUL_4239|M.ulcerans_Agy99           GMVFLLPGDPLAAIAGDRPLTPAVAQQLRARYHLDDPFLVQYAHYLGGVL
MAB_0427|M.abscessus_ATCC_1997      SLVYALPGDPIRALAGDRPFTPEVMAQLRERFHLNDPFLVRYGKYIVGFL
MLBr_01124|M.leprae_Br4923          CLTSMAFAPLDSLLQRSPHPPQAMVDAKAHALGLDKPIPIRYANWASHAI
                                     :     .            .            *: *:  ::  :    :

Mflv_2760|M.gilvum_PYR-GCK          TGDLGVSFRNGDPVTVTLLERLPATLSLGLAGIVIALAIALPAGIYAALR
Mvan_3774|M.vanbaalenii_PYR-1       TGDLGVSFRNGDPVTLTLLERLPATLSLGLVGIVIALAIALPAGIYAALR
TH_2645|M.thermoresistible__bu      RGDLGVSFRNGDPVTLVLLERLPATVSLALAGIAIALAIALPAGIWSALR
MSMEG_6866|M.smegmatis_MC2_155      HGDLGQSIFFDQPVVSLIGERLPATALLAVAALVLSLVISLPAGILASAH
Rv3665c|M.tuberculosis_H37Rv        HGDLGRAYS-GLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLR
Mb3689c|M.bovis_AF2122/97           HGDLGRAYS-GLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLR
MAV_0465|M.avium_104                RGDLGRAYS-GLPVSDVLAHAFPVTLRLSLIALAVEAVLGIGFGVIAGLR
MMAR_5153|M.marinum_M               HGDLGRAYS-GLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLR
MUL_4239|M.ulcerans_Agy99           HGDLGRAYS-GLPVSAVLAHAFPVTIRLAWIALAVEAVLGIGFGVIAGLR
MAB_0427|M.abscessus_ATCC_1997      HGDFGTDFQ-QRPVAQTVSQRLPVTLRLTVVAVAFETIIGITAGVLCAVR
MLBr_01124|M.leprae_Br4923          RGDFGTTIT-GQPVGSTLGRRVGVSLRLLIIGSLTGTVLGVTAGAWGAIR
                                     **:*       **   : . . .:  *   .      :.:  *   . :

Mflv_2760|M.gilvum_PYR-GCK          EGRLSDALVRISSQFGVSIPDFWMG-ILLIALFSTVLGWLPT-SGYRPLF
Mvan_3774|M.vanbaalenii_PYR-1       EGRLSDALVRISSQFGVSIPDFWMG-ILLIALFSTVLGWLPT-SGYRPLT
TH_2645|M.thermoresistible__bu      DGRAGAAAVRVASQVGVSVPDFWMG-ILLIALFASTLGWLPT-SGYRALS
MSMEG_6866|M.smegmatis_MC2_155      RGRITDTVISGIVLIGQSTPAFWIG-ILFILLFAVRLRVLPA-AGY----
Rv3665c|M.tuberculosis_H37Rv        QGGIFDSAVLVTGLVIIAIPIFVLG-FLAQFLFGVQLEIAPVTVGERA--
Mb3689c|M.bovis_AF2122/97           QGGIFDSAVLVTGLVIIAIPIFVLG-FLAQFLFGVQLEIAPVTVGERA--
MAV_0465|M.avium_104                QGGLFDSAVLITGLVIIAVPIFVLG-FLAQFVFGVRLGIAPVTVGNAA--
MMAR_5153|M.marinum_M               QGGIFDATVLLTGLIIIAVPIFVLG-FLAQYLFGVRLGLAPVTVGART--
MUL_4239|M.ulcerans_Agy99           QGGIFDATVLLTGLIIIAAPIFVLG-FLAQYLFGVRLGLAPVTVGART--
MAB_0427|M.abscessus_ATCC_1997      RGSFYDNLVLVTTTLLVSMPVFVLG-FLAQYLFGFKLGWFPI-AGIRD--
MLBr_01124|M.leprae_Br4923          QYQLSDRVVTLLALLVLSTPTFVIANLLILSALRVNWAFGIQLFDYTGET
                                            :     .  : * * :. :*    :           .     

Mflv_2760|M.gilvum_PYR-GCK          ED---------PAGWLRHIILPALTVAVVAAAIMTRYVRAAVLEVASMGY
Mvan_3774|M.vanbaalenii_PYR-1       ED---------PAGWLRHVVLPGLTVGVVAAAIMTRYVRSAVLEVAAMGY
TH_2645|M.thermoresistible__bu      DD---------PVGWLRHLVLPALTVGLVAAAIMTRYIRSAVLEVAAAGH
MSMEG_6866|M.smegmatis_MC2_155      -------------GGAAHLVLPAITLAIYSIAVVARVLRTSLAEELSADY
Rv3665c|M.tuberculosis_H37Rv        --------------SVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADY
Mb3689c|M.bovis_AF2122/97           --------------SVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADY
MAV_0465|M.avium_104                --------------TFTRLLLPGIVLGSVSFAYVVRLTRSTVAVNAHADY
MMAR_5153|M.marinum_M               --------------TLDRLLLPGMVLGAVSFAYVVRLTRSAVAANAHADY
MUL_4239|M.ulcerans_Agy99           --------------TLDRLLLPGMVLGAVSFAYVVRLTRSAVAANAHADY
MAB_0427|M.abscessus_ATCC_1997      --------------GWYSFLLPGLVLASLSMAYVARLTRTSMLETMDAEF
MLBr_01124|M.leprae_Br4923          SPGVYGGAWAHVIDRLRHLILPTLTLALVGAAGYSRYQRNAMLDVLSQDF
                                                      .:** :.:.  . *   *  * ::       .

Mflv_2760|M.gilvum_PYR-GCK          VRTARSKGLTPRVVTFRHTVRNALVPILTITGIQLATLLGGVIVVEVVFA
Mvan_3774|M.vanbaalenii_PYR-1       VRTARSKGLSPRIVTFRHTVRNALVPILTITGIQLATLLGGVIVVEVVFA
TH_2645|M.thermoresistible__bu      VRTARSKGLSPWVLTVRHTVRNALIPVLTITGIQLATILGGVIVVEVVFA
MSMEG_6866|M.smegmatis_MC2_155      IRTATAKGLSRRQVVVGHGLRNASLPVVTVVGLEFGSLLGGAILTEQVFS
Rv3665c|M.tuberculosis_H37Rv        VRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFN
Mb3689c|M.bovis_AF2122/97           VRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFN
MAV_0465|M.avium_104                VRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFN
MMAR_5153|M.marinum_M               VRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAVVTEGIFN
MUL_4239|M.ulcerans_Agy99           VRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAVVTEGIFN
MAB_0427|M.abscessus_ATCC_1997      VRTARAKGISESRILLRHTLRNSLIPVVTFIGADVGALLAGAVVTESVFN
MLBr_01124|M.leprae_Br4923          IRAARAKGLTRRRALLKHGLRTALIPMATLFAYGVAGLVTGALFVEKIFG
                                    :*:* :**::       * :*.: :*: *. .  .. :: *.:..* :* 

Mflv_2760|M.gilvum_PYR-GCK          WPGLGRLVFNAVAARDYPLIQGAVLLIAALFLLINLLVDVLYAVVDPRIR
Mvan_3774|M.vanbaalenii_PYR-1       WPGLGRLVFNAVAARDYPLIQGAVLLIAALFLVINLLVDVLYAVVDPRIR
TH_2645|M.thermoresistible__bu      WPGLGRLVYNAVAARDYPVIQGAVLLIAALFLLINLLVDLLYAIVDPRIR
MSMEG_6866|M.smegmatis_MC2_155      WPGIGRLTVEAISNRDFALVQGAVLFFALVFVVVNLLVDLSYTLLDPRVR
Rv3665c|M.tuberculosis_H37Rv        IHGVGGVLYQAVTRQETPTVVSIVTVLVLIYLITNLLVDLLYAALDPRIR
Mb3689c|M.bovis_AF2122/97           IHGVGGVLYQAVTRQETPTVVSIVTVLVLIYLITNLLVDLLYAALDPRIR
MAV_0465|M.avium_104                IHGVGGVLYQAVTRQEAPTVVSIVTVLVLIYLVTNLVVDLLYAVLDPRIR
MMAR_5153|M.marinum_M               IHGVGGVLYQAVTRQEAPTVVSIVTVLVMVYLLTNLLVDLLYAALDPRIR
MUL_4239|M.ulcerans_Agy99           IHGVGGVLYQAVTRQEAPTVVSIVTVLVMVYLLTNLLVDLLYAALDPRIR
MAB_0427|M.abscessus_ATCC_1997      IPGLGRATFDAVRNQEGAVVVSILTLIVFFYIFFNLVVDILYALLDPRIR
MLBr_01124|M.leprae_Br4923          WHGMGEWMVQGVATQDTNIIAAITIFFGTVILLAGLLSDVIYAALDPRVR
                                      *:*    :.:  ::   : .   .:  . :. .*: *: *: :***:*

Mflv_2760|M.gilvum_PYR-GCK          LG-
Mvan_3774|M.vanbaalenii_PYR-1       LG-
TH_2645|M.thermoresistible__bu      LA-
MSMEG_6866|M.smegmatis_MC2_155      LGR
Rv3665c|M.tuberculosis_H37Rv        YG-
Mb3689c|M.bovis_AF2122/97           YG-
MAV_0465|M.avium_104                YG-
MMAR_5153|M.marinum_M               YG-
MUL_4239|M.ulcerans_Agy99           YG-
MAB_0427|M.abscessus_ATCC_1997      YE-
MLBr_01124|M.leprae_Br4923          VS-