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SGIASAALILSLALVVLPGSPRCRLTPDDTGRRVLLVGARRVAWGVGCVAVGVAALLPLPTVVAVAVLGA TLGLRYRRRRRYLRRSREGQALEAALELVVGELRAGAHPVRAFSIAADETGGPVAVALRAVAARARLGAD VTAGLLAAARSSALPAYWERLAVCWQLGSDHGLAIASLMRAAQRDVAERQRFSARVSAGMAGARASAAIL AILPLLGVLLGQLIGARPLSFLLTGRVGGWLLVVGLTLACAGLLWSDRITDRPVL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3658c | - | - | 100% (266) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3682c | - | 1e-145 | 100.00% (266) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1385 | - | 1e-67 | 55.04% (258) | type II secretion system protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0471 | - | 1e-55 | 48.64% (257) | hypothetical protein MAB_0471 |
| M. marinum M | MMAR_5146 | - | 3e-86 | 64.02% (264) | hypothetical protein MMAR_5146 |
| M. avium 104 | MAV_0509 | - | 6e-93 | 67.79% (267) | type II secretion system protein F |
| M. smegmatis MC2 155 | MSMEG_6168 | - | 2e-66 | 60.49% (205) | type II secretion system protein F |
| M. thermoresistible (build 8) | TH_3280 | - | 4e-45 | 57.24% (152) | PUTATIVE type II secretion system protein |
| M. ulcerans Agy99 | MUL_4231 | - | 4e-78 | 63.93% (244) | hypothetical protein MUL_4231 |
| M. vanbaalenii PYR-1 | Mvan_5406 | - | 7e-67 | 55.51% (263) | type II secretion system protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3658c|M.tuberculosis_H37Rv MSGIASAALILSLALVVLPGSPRCRLTPDDTGRR----VLLVGARRVAWG
Mb3682c|M.bovis_AF2122/97 MSGIASAALILSLALVVLPGSPRCRLTPDDTGRR----VLLVGARRVAWG
MAV_0509|M.avium_104 MTGPVVGALLLAVALVVGPPSPRRRLGVAVTGSRRPSARRLAGLGWVAAG
MMAR_5146|M.marinum_M MTGLVLAALMVAAAIAVLSVPVRRRISVNDVRGHS---NWLSATRWLGCL
MUL_4231|M.ulcerans_Agy99 MTGLVLAALMVAAAIAVLSVPVRRRISVNDVRGHS---NWLSATRWLGCL
Mflv_1385|M.gilvum_PYR-GCK ---MTLAALALAVAVLTAPTDARLRAPVLRRTSTP----RRRLPGQLPAA
Mvan_5406|M.vanbaalenii_PYR-1 ---MTAAALALAAAVLVAPAGSRWRR-VLSAPPSR----RLRLPVPVCGA
TH_3280|M.thermoresistible__bu --------------------------------------------------
MSMEG_6168|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0471|M.abscessus_ATCC_1997 ---MTPQALVLLAAALLLVPQRYRRLDQPGMSPVR------WTGKLVAAP
Rv3658c|M.tuberculosis_H37Rv VGCVAVGVAALLPLPTVVAVAVLGATLGLRYRRRRRYLRRSREGQALEAA
Mb3682c|M.bovis_AF2122/97 VGCVAVGVAALLPLPTVVAVAVLGATLGLRYRRRRRYLRRSREGQALEAA
MAV_0509|M.avium_104 AGCAAL---AVLPLPSVLAGAVVAATAGLRHRRRGRIRRAAGEGRALETA
MMAR_5146|M.marinum_M LACALAGAVLVMPLTTVLAAVVVAGTASRRRRRRLVRARGVREGRALEAA
MUL_4231|M.ulcerans_Agy99 LACALAGAVLVMPLTTVLAVAVVAGTASRRRRRRLVRARGVREGWALEAA
Mflv_1385|M.gilvum_PYR-GCK IACLTV--AAVHTPTTAAALGLLLATLSARRRVTRAHRRRTAEAAALQDA
Mvan_5406|M.vanbaalenii_PYR-1 LLCAVT--ALLLSPAAVLAAALLMATLSVRSRAARRRRNRVTEAAALQGA
TH_3280|M.thermoresistible__bu --------------------------------------------------
MSMEG_6168|M.smegmatis_MC2_155 ----------MLPLPVALTAGVVAGTVVVRRRDRAAAQHRRDESAALQGA
MAB_0471|M.abscessus_ATCC_1997 LSALVLTALWLLPLSVVVSAVVVAGTGALRWRRRRRSRVESEELDCTASG
Rv3658c|M.tuberculosis_H37Rv LELVVGELRAGAHPVRAFSIAADETGGPVAVALRAVAARARLGADVTAGL
Mb3682c|M.bovis_AF2122/97 LELVVGELRAGAHPVRAFSIAADETGGPVAVALRAVAARARLGADVTAGL
MAV_0509|M.avium_104 LDVLVGELRAGSHPVRAFDVAAGETAGPVAVALRSVAARARLGADVAAGL
MMAR_5146|M.marinum_M LEILVGELRVGAHPVRAFGVAADETDGPVAAAMRGVAAHARLGADVTGGL
MUL_4231|M.ulcerans_Agy99 LEILVGELRVGAHPVRAFGVAADETDGPVAAAMRGVAAHARLGADVTGGL
Mflv_1385|M.gilvum_PYR-GCK LDVLVGELRVGAHPVAAITVAGHEARGRIAESLNAVAARALLGADVPAGL
Mvan_5406|M.vanbaalenii_PYR-1 LDVLIGELRVGAHPVAAMNTAAQESDARIAGALGAVAARALLGADVAAGL
TH_3280|M.thermoresistible__bu --------------VSAVEVAAREVSGTTGLALREVAARARLGGEVSSGL
MSMEG_6168|M.smegmatis_MC2_155 LDVLVGELRVGAHPVDAFGAAAGESGGPVAEGMRAVAARARLGADVAAGL
MAB_0471|M.abscessus_ATCC_1997 LDVVVGELRVGAHPVRAFEIAAVELNGAAGEAFAAIAARARLGVNVDR--
* *. *. * . . .: :**:* ** :*
Rv3658c|M.tuberculosis_H37Rv LAAARSSALPAYWERLAVCWQLGSDHGLAIASLMRAAQRDVAERQRFSAR
Mb3682c|M.bovis_AF2122/97 LAAARSSALPAYWERLAVCWQLGSDHGLAIASLMRAAQRDVAERQRFSAR
MAV_0509|M.avium_104 AAASRGSARPEHWQRLALCWRLAGDHGLGIATLMRAAQRDIAERQRFSAR
MMAR_5146|M.marinum_M RAAARRSALPSHWERLAVYWQLASDHGLAIATLMRAAQRDVAQRQRFSAK
MUL_4231|M.ulcerans_Agy99 RAAARRSALPAHWERLAVYWQLASDHGLAIATLMRAAQRDVAQRQRFSAK
Mflv_1385|M.gilvum_PYR-GCK RAEGRRSPSPGHWDRLAVCWQLAQTHGLAIAALMRAAQRDITERERFRGR
Mvan_5406|M.vanbaalenii_PYR-1 RAQGRRSLLPGHWDRLAVCWHLAQAQGLAIATLMLAAQRDIAERERFRGR
TH_3280|M.thermoresistible__bu RSVAARSASPGNWERLAVCWRLAERYGLAMATLMRTAQHDIRERERFSAK
MSMEG_6168|M.smegmatis_MC2_155 DDVARASQLPGHWQRLAVCWRLAQTHGLALGTLMRAAHEDIVERERFSAR
MAB_0471|M.abscessus_ATCC_1997 -ALPRSVPARAQWNRITRSWSLAQRHGLAVADLLDACRADLQERQQFTAR
*:*:: * *. **.:. *: :.: *: :*::* .:
Rv3658c|M.tuberculosis_H37Rv VSAGMAGARASAAILAILPLLGVLLGQLIGARPLSFLLTGRVGGWLLVVG
Mb3682c|M.bovis_AF2122/97 VSAGMAGARASAAILAILPLLGVLLGQLIGARPLSFLLTGRVGGWLLVVG
MAV_0509|M.avium_104 VSSSLAGARATAAILAALPVLGVLLGQLIGARPLDFLLGGQVGGWLLLVG
MMAR_5146|M.marinum_M VSAGLAGARASAGILAGLPVLGVVLGQLIGAQPLAFLLGGHLGGWLLVVG
MUL_4231|M.ulcerans_Agy99 VSAGLAGARASAGILAGLPVLGVVLGQLIGAQPLAFLLGGHLGGWLL--G
Mflv_1385|M.gilvum_PYR-GCK VESGMAGARATAVILAGLPVLGVLLGHAIGAEPLAFLLSGGAGGWLLLVG
Mvan_5406|M.vanbaalenii_PYR-1 VEAGLAGARATAAILAGLPVLGVLLGHAIGAEPLSFLFSGGFGGWLLVTG
TH_3280|M.thermoresistible__bu VHADLAGARTTATLLAALPVLGIGLGQAIGAEPVRFLCTDGIGAWLLVTG
MSMEG_6168|M.smegmatis_MC2_155 VRAAMAGPRTTALVLAGLPLAGIALGQAIGAAPVAFLVASGAGGWLLVIG
MAB_0471|M.abscessus_ATCC_1997 VNAGLAGPRATAVVLTGLPVAGIGLGQMIGARPLSVLCAGGVGGALLVVG
* : :**.*::* :*: **: *: **: *** *: .* . *. ** *
Rv3658c|M.tuberculosis_H37Rv LTLACAGLLWSDRITDRPVL
Mb3682c|M.bovis_AF2122/97 LTLACAGLLWSDRITDRPVL
MAV_0509|M.avium_104 ATLACAGLLWADRIVDRVMA
MMAR_5146|M.marinum_M LALAAGGLWWSDRITDRVMP
MUL_4231|M.ulcerans_Agy99 FAWPWRPVVCGGRTGSPTG-
Mflv_1385|M.gilvum_PYR-GCK TVFVCAGLLWSDRITVQVLT
Mvan_5406|M.vanbaalenii_PYR-1 TVFVCCGLLWSDRITTGVLT
TH_3280|M.thermoresistible__bu AALLCCGQLWSDRIIEGVVK
MSMEG_6168|M.smegmatis_MC2_155 VVLACAGLLWSDRITAEVKS
MAB_0471|M.abscessus_ATCC_1997 VTLACAGLLWADAITGKALR
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