For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SGVFTRLVGQQAVEAELLATAKAARRDSAHSAGGGGTMTHAWLLTGPPGSGRSVAALCFAAALQCTSGGE PGCGRCRACTTTLAGTHADVRRVIPEGLSIGVDEMRAIVQIAARRPTTGHWQIVVIEDADRLTEGAANAL LKVVEEPPPSTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPSTHAIAQVLSDGDGLDPDTANWAASVSGG HVGRARRLATDPQARQRRERALGLARDAATPSRAYAAAEELVAGAEAEALALTAQRIEAETEELRTALGA GGTGKGTGAALRGATGAMKDLERRQKSRQTRASRDALDRALIDLATYFRDALLVAAHAGGVRANHPDMAD RVAALAAHAPPERLLRCIEAVLACREALAVNVKPKFAVDAMVATIGQELR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3644c | - | - | 100% (401) | DNA polymerase III subunit delta' |
| M. tuberculosis H37Rv | Rv3721c | dnaZX | 5e-19 | 24.82% (407) | DNA polymerase III subunits gamma and tau |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3668c | - | 0.0 | 100.00% (401) | DNA polymerase III subunit delta' |
| M. gilvum PYR-GCK | Mflv_1396 | - | 0.0 | 82.88% (403) | DNA polymerase III subunit delta' |
| M. leprae Br4923 | MLBr_00202 | - | 0.0 | 84.41% (404) | DNA polymerase III subunit delta' |
| M. abscessus ATCC 19977 | MAB_0491 | - | 1e-167 | 75.50% (404) | DNA polymerase III subunit delta' |
| M. marinum M | MMAR_5136 | - | 0.0 | 85.04% (401) | hypothetical protein MMAR_5136 |
| M. avium 104 | MAV_0520 | - | 0.0 | 87.60% (387) | DNA polymerase III subunit delta' |
| M. smegmatis MC2 155 | MSMEG_6153 | - | 0.0 | 83.04% (401) | DNA polymerase III subunit delta' |
| M. thermoresistible (build 8) | TH_0617 | - | 8e-31 | 85.14% (74) | POSSIBLE DNA POLYMERASE |
| M. ulcerans Agy99 | MUL_4220 | - | 0.0 | 85.29% (401) | DNA polymerase III subunit delta' |
| M. vanbaalenii PYR-1 | Mvan_5394 | - | 0.0 | 80.79% (406) | DNA polymerase III subunit delta' |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1396|M.gilvum_PYR-GCK ----MAGVFSRLVGQDTVEAELIAAARAARGDSVHD---DDPAETGTMTH
Mvan_5394|M.vanbaalenii_PYR-1 ----MTGVFSRLVGQDAVETELTAAARAARGDSPHTSGLDVSGVTGTMTH
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 ----MSGVFSRLVGQHAVEQELVAAAAAARGDSAHS-----GVATGTMTH
Rv3644c|M.tuberculosis_H37Rv ----MSGVFTRLVGQQAVEAELLATAKAARRDSAHS-----AGGGGTMTH
Mb3668c|M.bovis_AF2122/97 ----MSGVFTRLVGQQAVEAELLATAKAARRDSAHS-----AGGGGTMTH
MMAR_5136|M.marinum_M MSTVMSGVFARLVGQGAVESELLAAARSARSDSTHS-----SGFDGDMTH
MUL_4220|M.ulcerans_Agy99 ----MSGVFARLVGQGAVESELLAAARSARSDSTHS-----SGFDGDMTH
MLBr_00202|M.leprae_Br4923 ----MSGVFTRLVGQDAVEAELLAAAKAARSDLVHS-----RPADGTMTH
MAV_0520|M.avium_104 -----------------MKAELLGAARAARGDAGHS-----DAGAGTMTH
MAB_0491|M.abscessus_ATCC_1997 ----MSGVFGRLVDQGAVVSTLSSSALAARGD-----------DAGRMTH
Mflv_1396|M.gilvum_PYR-GCK AWLITGPPGSGRSIAALCFAAALQCTS---EGRPGCGECRACTTTMAGTH
Mvan_5394|M.vanbaalenii_PYR-1 AWLITGPPGSGRSIAALCFAAALQCTS---DGTPGCGECRACATTMAGTH
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 AWLITGPPGSGRSVAALCFAAALQCTS---DGVPGCGECRACTTTMAGTH
Rv3644c|M.tuberculosis_H37Rv AWLLTGPPGSGRSVAALCFAAALQCTS---GGEPGCGRCRACTTTLAGTH
Mb3668c|M.bovis_AF2122/97 AWLLTGPPGSGRSVAALCFAAALQCTS---GGEPGCGRCRACTTTLAGTH
MMAR_5136|M.marinum_M AWLITGPPGSGRSIAALCFAAALQCTS---DGDPGCGRCRSCLTTMAGTH
MUL_4220|M.ulcerans_Agy99 AWLITGPPGSGRSIAALCFAAALQCTS---DGDPGCGRCRSCLTTMAGTH
MLBr_00202|M.leprae_Br4923 AWLITGPPGSGRSVAAVCFAAALQCTADFQDGGPGCGRCRACTTTMAGTH
MAV_0520|M.avium_104 AWLITGPPGSGRSVAALCFAAALQCTA---DGEPGCGRCHACTTTLAGTH
MAB_0491|M.abscessus_ATCC_1997 AWLFTGPPGSGRSVAALCFAAALQCES---EDVAGCGACRPCTTTMAGTH
Mflv_1396|M.gilvum_PYR-GCK ADVRRIIPEGLSIGVDAMRAIVQIASRRPGTGRWQIVVVEDADRLTEGAA
Mvan_5394|M.vanbaalenii_PYR-1 ADVRRIIPEGLSIGVDAMRAIVQIASRRPGTGRWQIVVIEDADRLTEGAA
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 ADVRRIVPEGLSIAVKEMREIVQIASRRPGTGRWQVVVIEDADRLTEGAA
Rv3644c|M.tuberculosis_H37Rv ADVRRVIPEGLSIGVDEMRAIVQIAARRPTTGHWQIVVIEDADRLTEGAA
Mb3668c|M.bovis_AF2122/97 ADVRRVIPEGLSIGVDEMRAIVQIAARRPTTGHWQIVVIEDADRLTEGAA
MMAR_5136|M.marinum_M ADVRRVIPEGLSIGVDDMRAIVQIASRRPTTGRHQIVLIEDADRLTEGAA
MUL_4220|M.ulcerans_Agy99 ADVRRVIPEGLSIGVDDMRAIVQIASRRPTTGRHQIVLIEDADRLTEGAA
MLBr_00202|M.leprae_Br4923 ADVRRVIPDGLSIGVDEMRAIVHEASRRPSTGYWQIVLIEDADRLTEGAA
MAV_0520|M.avium_104 ADVRRVVPEGLSIGVDGMRAIVQIAARRPATGNWQIVVIEDADRLTEGAA
MAB_0491|M.abscessus_ATCC_1997 ADVRRVVPEGLSIGVDEMRAIVQAAWRRPSTGRWLVVLIEDADRLTEGAG
Mflv_1396|M.gilvum_PYR-GCK NALLKVVEEPPPSTVFLLCAPSVDPEDIAITLRSRCRHVALVTPPVEAIA
Mvan_5394|M.vanbaalenii_PYR-1 NALLKVVEEPPPSTVFLLCAPSVDPEDIAITLRSRCRHVALVTPPVDAIA
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 NALLKVVEEPPPSTVFLLCAPSVDPEDIAITLRSRCRHIALTTPSIDAIA
Rv3644c|M.tuberculosis_H37Rv NALLKVVEEPPPSTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPSTHAIA
Mb3668c|M.bovis_AF2122/97 NALLKVVEEPPPSTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPSTHAIA
MMAR_5136|M.marinum_M NALLKVVEEPPASTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPPTTAIA
MUL_4220|M.ulcerans_Agy99 NALLKVVEEPPASTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPPTTAIA
MLBr_00202|M.leprae_Br4923 NALLKVVEEPPSSTVFLLCAPSVAPEDIAVTLRSRCRHVALVTPSHAAIA
MAV_0520|M.avium_104 NALLKVVEEPPPSTVFLLCAPSVDPEDVAITLRSRCRHVALVTPSTEAIA
MAB_0491|M.abscessus_ATCC_1997 NVLLKVVEEPPPRTVFLLCAPSVDPEDISITLRSRCRHVALVTPSVAAIA
Mflv_1396|M.gilvum_PYR-GCK QVLIDADGLSAAEARWAASVSGGHVGRARRLATDDEARERRKRALGLARD
Mvan_5394|M.vanbaalenii_PYR-1 RVLIDSDGLPEKDAEWAAAVSGGHVGRARRLATDERARERRQRALGLARD
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 DVLITGDGLPPEDARWAASVCGGHVGRARRLATDPEARERRKRALGLARD
Rv3644c|M.tuberculosis_H37Rv QVLSDGDGLDPDTANWAASVSGGHVGRARRLATDPQARQRRERALGLARD
Mb3668c|M.bovis_AF2122/97 QVLSDGDGLDPDTANWAASVSGGHVGRARRLATDPQARQRRERALGLARD
MMAR_5136|M.marinum_M QVLIDNDGLAAETANWAASVSGGHVGRARRLATDPEARQRRERALGLVRD
MUL_4220|M.ulcerans_Agy99 QVLIDNDGLAAETANWAASVSGGHVGRARRLATDPEARQRRERALGLVRD
MLBr_00202|M.leprae_Br4923 RVLIDSDGLAADTANWAALVSGGHVGLARRLATDPEAQQRRERAFGLIRD
MAV_0520|M.avium_104 RVLVDSDGLTPETADWAASVSGGHVGRARRLATDPEARQRRERALGLVRD
MAB_0491|M.abscessus_ATCC_1997 QVLVDRDGIDAEQAQWAASVSGGHVGRARRLATDEQARARRLKALGLARE
Mflv_1396|M.gilvum_PYR-GCK AATPSRAYAAAEELVATAEAEAKALTGDRNEAESEELRTALGAGGTGKGT
Mvan_5394|M.vanbaalenii_PYR-1 AATPSRAYAAAEELVATAEAEAKALTEDRNEVEAEELRTALGAGGTGKGT
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 AATPSRAYAAAEEMVAVAEAEAVALTADRNENETEELKTALGAGGTGKGT
Rv3644c|M.tuberculosis_H37Rv AATPSRAYAAAEELVAGAEAEALALTAQRIEAETEELRTALGAGGTGKGT
Mb3668c|M.bovis_AF2122/97 AATPSRAYAAAEELVAGAEAEALALTAQRIEAETEELRTALGAGGTGKGT
MMAR_5136|M.marinum_M AATPARAYAAAEELVAAAEAEALALTSDRAEAETEELRTALGAGGTGKGT
MUL_4220|M.ulcerans_Agy99 AATPARAYAAAEELVAAAEAEALALTSDRAEAETEELRTALGAGGTGKGT
MLBr_00202|M.leprae_Br4923 AVVPSRAYAVAEELVAAAEAEALVLTAERAEAETEELRTALGAGGTGKGT
MAV_0520|M.avium_104 AATPSRAYAAAEELVAAAEAEAVVLTAERAEAETEELRTALGAGGTGKGT
MAB_0491|M.abscessus_ATCC_1997 AATPSRAYAAAEELVTSADAEAKELTAARNEAEEEELKTALGAGGTGKGA
Mflv_1396|M.gilvum_PYR-GCK AGTMRGAAGALKELEKRQKSRQTRASRDALDRALIDLATYFRDALLVSAG
Mvan_5394|M.vanbaalenii_PYR-1 AGTMRGAAGALKELEKRQKSRHTRASRDALDRALIDLATYFRDALLVSSG
TH_0617|M.thermoresistible__bu --------------------------------------MYFRDALLVATG
MSMEG_6153|M.smegmatis_MC2_155 AGTMRGAAGALKELEKRQKSRQTRASRDALDRALIDLATYFRDALLVSSG
Rv3644c|M.tuberculosis_H37Rv GAALRGATGAMKDLERRQKSRQTRASRDALDRALIDLATYFRDALLVAAH
Mb3668c|M.bovis_AF2122/97 GAALRGATGAMKDLERRQKSRQTRASRDALDRALIDLATYFRDALLVAAH
MMAR_5136|M.marinum_M AGTMRGSAGAIKDLERRQKSRHTRAARDALDRALIDLATYFRDALLVSAK
MUL_4220|M.ulcerans_Agy99 AGTMRGSAGAIKDLERRQKSRHTRAARDALDRALIDLATYFRDALLVSAK
MLBr_00202|M.leprae_Br4923 AGALRSVTGAIKDLERRQKSRQTRASRDALDRVLIDLATYFRDALLVSAN
MAV_0520|M.avium_104 AGAMRGAAGAIKDLERRQKSRQTRASRDALDRALIDLATYFRDALMASSG
MAB_0491|M.abscessus_ATCC_1997 ATALRGSAGVLKDLERKQKSRQTRASRDALDRTLIDLATYFRDALVLSFG
******: :
Mflv_1396|M.gilvum_PYR-GCK ATD---VVANHPDMADKVAALAAHAPPDKLLRCIEAVLECREALAVNVKP
Mvan_5394|M.vanbaalenii_PYR-1 ATD---VVANHPDMAEKVAAMAAHASPEKLLRCIEAVLECREALAVNVKP
TH_0617|M.thermoresistible__bu ADG---IRREHPDMADKVAALAAHAPPEKLLRCIEAVLECREALAVNVKP
MSMEG_6153|M.smegmatis_MC2_155 ANT---VTANHPDMAEKVAALAAHAAPDRLLRCIEAVLECREALAVNVKP
Rv3644c|M.tuberculosis_H37Rv AGG---VRANHPDMADRVAALAAHAPPERLLRCIEAVLACREALAVNVKP
Mb3668c|M.bovis_AF2122/97 AGG---VRANHPDMADRVAALAAHAPPERLLRCIEAVLACREALAVNVKP
MMAR_5136|M.marinum_M ADQ---PRANHPDMADRVAALAAHATPERLLRCIEAVLNCREALSINVKP
MUL_4220|M.ulcerans_Agy99 ADQ---PRANHPDMADRVAALAAHATPERLLRCIEAVLNCREALSINVKP
MLBr_00202|M.leprae_Br4923 AGS---VQPNHPDMADRVAVLACHATPERLLRCIEAVLECREALAVNVKP
MAV_0520|M.avium_104 AGA---VRANHPDMAERVAALAAHAPPERLLRCIEAVLECREALAVNVKP
MAB_0491|M.abscessus_ATCC_1997 AAGQGRVALHHPDMADRLGPMVDRVPPEQLLKCIEAVLECREALAVNVKP
* .*****:::. :. :..*::**:****** *****::****
Mflv_1396|M.gilvum_PYR-GCK KFAVDAMVGTVGQALRS--
Mvan_5394|M.vanbaalenii_PYR-1 KFAVDAMVGTVGQALRS--
TH_0617|M.thermoresistible__bu KFAVDAMVATVGQALRG--
MSMEG_6153|M.smegmatis_MC2_155 KFAVDAMVATIGQALRG--
Rv3644c|M.tuberculosis_H37Rv KFAVDAMVATIGQELR---
Mb3668c|M.bovis_AF2122/97 KFAVDAMVATIGQELR---
MMAR_5136|M.marinum_M KFAVDAMVAAIGQQLQ---
MUL_4220|M.ulcerans_Agy99 KFAVDAMVAAIGQQLR---
MLBr_00202|M.leprae_Br4923 KFAVDALVATIGQELRY--
MAV_0520|M.avium_104 KFAVDAMVATIGQQLG---
MAB_0491|M.abscessus_ATCC_1997 KFAIDALVATAGQALRPSE
***:**:*.: ** *