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ALYRKYRPASFAEVVGQEHVTAPLSVALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTANPCG VCESCVSLAPNAPGSIDVVELDAASHGGVDDTRELRDRAFYAPVQSRYRVFIVDEAHMVTTAGFNALLKI VEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPPRTMRALLARICEQEGVVVDDAVYPLVIRAGGG SPRDTLSVLDQLLAGAADTHVTYTRALGLLGVTDVALIDDAVDALAACDAAALFGAIESVIDGGHDPRRF ATDLLERFRDLIVLQSVPDAASRGVVDAPEDALDRMREQAARIGRATLTRYAEVVQAGLGEMRGATAPRL LLEVVCARLLLPSASDAESALLQRVERIETRLDMSIPAPQAVPRPSAAAAEPKHQPAREPRPVLAPTPAS SEPTVAAVRSMWPTVRDKVRLRSRTTEVMLAGATVRALEDNTLVLTHESAPLARRLSEQRNADVLAEALK DALGVNWRVRCETGEPAAAASPVGGGANVATAKAVNPAPTANSTQRDEEEHMLAEAGRGDPSPRRDPEEV ALELLQNELGARRIDNA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3721c | dnaZX | - | 100% (578) | DNA polymerase III subunits gamma and tau |
M. tuberculosis H37Rv | Rv3644c | - | 8e-19 | 24.82% (407) | DNA polymerase III subunit delta' |
M. tuberculosis H37Rv | Rv2559c | - | 2e-08 | 24.06% (345) | recombination factor protein RarA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3748c | dnaZX | 0.0 | 100.00% (578) | DNA polymerase III subunits gamma and tau |
M. gilvum PYR-GCK | Mflv_1281 | - | 0.0 | 68.89% (659) | DNA polymerase III subunits gamma and tau |
M. leprae Br4923 | MLBr_02335 | dnaZX | 0.0 | 78.24% (602) | DNA polymerase III subunits gamma and tau |
M. abscessus ATCC 19977 | MAB_0309 | - | 0.0 | 66.26% (661) | DNA polymerase III, subunit gamma/tau |
M. marinum M | MMAR_5240 | dnaZX | 0.0 | 76.37% (639) | DNA polymerase III (subunit gamma/tau) DnaZX |
M. avium 104 | MAV_0382 | - | 0.0 | 79.64% (614) | DNA polymerase III subunits gamma and tau |
M. smegmatis MC2 155 | MSMEG_6285 | - | 0.0 | 80.00% (445) | DNA polymerase III subunits gamma and tau |
M. thermoresistible (build 8) | TH_1299 | dnaZX | 0.0 | 83.54% (407) | DNA POLYMERASE III (SUBUNIT GAMMA/TAU) DNAZ/X |
M. ulcerans Agy99 | MUL_4315 | dnaZX | 0.0 | 77.35% (627) | DNA polymerase III subunits gamma and tau |
M. vanbaalenii PYR-1 | Mvan_5534 | - | 0.0 | 71.96% (649) | DNA polymerase III subunits gamma and tau |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1281|M.gilvum_PYR-GCK ----------------MALYRKYRPASFAEVVGQEHVTEPLSTALNSGRI Mvan_5534|M.vanbaalenii_PYR-1 ----------------MALYRKYRPATFADVVGQEHVTEPLSTALNSGRI Rv3721c|M.tuberculosis_H37Rv ----------------MALYRKYRPASFAEVVGQEHVTAPLSVALDAGRI Mb3748c|M.bovis_AF2122/97 ----------------MALYRKYRPASFAEVVGQEHVTAPLSVALDAGRI MMAR_5240|M.marinum_M ----------------MALYRKYRPATFAEVVGQEHVTEPLSIALEAGRI MUL_4315|M.ulcerans_Agy99 ----------------MALYRKYRPATFAEVVGQEHVTEPLSIALEAGRI MLBr_02335|M.leprae_Br4923 ----------------MTLYRKYRPAAFAEVVGQEHVTEPLSIALEAGRI MAV_0382|M.avium_104 ----------------MALYRKYRPATFAEVVGQEHVTEPLSIALEAGRI MSMEG_6285|M.smegmatis_MC2_155 ----------------MALYRKYRPATFSEVVGQEHVTEPLCTALTAGRI MAB_0309|M.abscessus_ATCC_1997 MAGARNRLWAPVPLLSVALYRKYRPATFAEVVGQEHVTGPLTTALDAGRI TH_1299|M.thermoresistible__bu ----------------VALYRKYRPATFAEVVGQEHVTEPLSVALSSGRI ::********:*::******** ** ** :*** Mflv_1281|M.gilvum_PYR-GCK NHAYLFSGPRGCGKTSSARILARSLNCEQGPTATPCGVCDSCVALAPNGP Mvan_5534|M.vanbaalenii_PYR-1 NHAYLFSGPRGCGKTSSARILARSLNCAEGPTATPCGVCDSCVALAPNGP Rv3721c|M.tuberculosis_H37Rv NHAYLFSGPRGCGKTSSARILARSLNCAQGPTANPCGVCESCVSLAPNAP Mb3748c|M.bovis_AF2122/97 NHAYLFSGPRGCGKTSSARILARSLNCAQGPTANPCGVCESCVSLAPNAP MMAR_5240|M.marinum_M NHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGTCESCQALAPSAP MUL_4315|M.ulcerans_Agy99 NHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGTCESCQALAPSAP MLBr_02335|M.leprae_Br4923 NHAYLFSGPRGCGKTSSARILARSLNCAQGTTATPCGVCESCLSLAPNAP MAV_0382|M.avium_104 NHAYLFSGPRGCGKTSSARILARSLNCVQGPTATPCGVCDSCLALAPNAP MSMEG_6285|M.smegmatis_MC2_155 NHAYLFSGPRGCGKTSSARILARSLNCDQGPTPTPCGVCDSCVALAPNGP MAB_0309|M.abscessus_ATCC_1997 NHAYLFSGPRGCGKTSSARILARSLNCVQGPTSTPCGTCESCVALAPNGS TH_1299|M.thermoresistible__bu NHAYLFSGPRGCGKTSSARILARSLNCVEGPTPTPCGSCDSCVALAPNGP *************************** :*.*..*** *:** :***... Mflv_1281|M.gilvum_PYR-GCK GNMDVTELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAG Mvan_5534|M.vanbaalenii_PYR-1 GNVDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAG Rv3721c|M.tuberculosis_H37Rv GSIDVVELDAASHGGVDDTRELRDRAFYAPVQSRYRVFIVDEAHMVTTAG Mb3748c|M.bovis_AF2122/97 GSIDVVELDAASHGGVDDTRELRDRAFYAPVQSRYRVFIVDEAHMVTTAG MMAR_5240|M.marinum_M GSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRVFIIDEAHMVTTAG MUL_4315|M.ulcerans_Agy99 GSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRVFIIDEAHMVTTAG MLBr_02335|M.leprae_Br4923 GHIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRVFIVDEAHMVTTAG MAV_0382|M.avium_104 GSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRVFIVDEAHMVTTAG MSMEG_6285|M.smegmatis_MC2_155 GNVDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAG MAB_0309|M.abscessus_ATCC_1997 GNVDVIELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIIDEAHMVTTAG TH_1299|M.thermoresistible__bu GNVDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAG * :** ************************.*****:**:********** Mflv_1281|M.gilvum_PYR-GCK FNALLKIVEEPPEHLIFVFATTEPEKVLPTIRSRTHHYPFRLLAPKTMRT Mvan_5534|M.vanbaalenii_PYR-1 FNALLKIVEEPPEHLIFVFATTEPEKVLPTIRSRTHHYPFRLLAPKTMRT Rv3721c|M.tuberculosis_H37Rv FNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPPRTMRA Mb3748c|M.bovis_AF2122/97 FNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPPRTMRA MMAR_5240|M.marinum_M FNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPPRTMRG MUL_4315|M.ulcerans_Agy99 FNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPRRTMRG MLBr_02335|M.leprae_Br4923 FNALLKIVEEPPDHLIFIFATTEPEKVLPTIRSRTHHYPFRLLSPRTMRA MAV_0382|M.avium_104 FNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPPKTMRA MSMEG_6285|M.smegmatis_MC2_155 FNALLKIVEEPPDHLIFVFATTEPEKVLPTIRSRTHHYPFRLLAPRTMRP MAB_0309|M.abscessus_ATCC_1997 FNALLKIVEEPPEHLIFVFATTEPEKVLPTIRSRTHHYPFRLLAPKTMRT TH_1299|M.thermoresistible__bu FNALLKIVEEPPDHLIFVFATTEPEKVLPTIRSRTHHYPFRLLAPRTMRG ************:****:*************************. :*** Mflv_1281|M.gilvum_PYR-GCK LIEKIVASEQVAVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAHADESGT Mvan_5534|M.vanbaalenii_PYR-1 LIEKIVASESVRVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAEDD---- Rv3721c|M.tuberculosis_H37Rv LLARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAADT---- Mb3748c|M.bovis_AF2122/97 LLARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAADT---- MMAR_5240|M.marinum_M LIGRICEQEGVVVDEAVYPLVTRAGGGSPRDTLSVLDQLVAGAQSN---- MUL_4315|M.ulcerans_Agy99 LIGRICEQEGVVVDEAVYPLVTRAGGGSPRDTLSVLDQLVAGAQSN---- MLBr_02335|M.leprae_Br4923 LVGRICAQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLVAGAEGE---- MAV_0382|M.avium_104 LIGRICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLVAGAEGG---- MSMEG_6285|M.smegmatis_MC2_155 LLERICAEENVEVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGSEQGANG- MAB_0309|M.abscessus_ATCC_1997 LVEGICAQENVSVDDPVYPLVIRAGAGSPRDTLSVLDQLLAGADEE---- TH_1299|M.thermoresistible__bu LIEKICAQERVHVDDAVLPLVIRAGGGSPRDTLSVLDQLLAGSEHGPDG- *: * .* * **:.* *** ***.*************:**: Mflv_1281|M.gilvum_PYR-GCK SHVAYQRALSLLGATDVALIDEAIDALAANDSAALFGAVEGVIDAGHDPR Mvan_5534|M.vanbaalenii_PYR-1 -HVAYQRALSLLGATDVALIDEAVDALAADDAAALFGAVEGVVDAGHDPR Rv3721c|M.tuberculosis_H37Rv -HVTYTRALGLLGVTDVALIDDAVDALAACDAAALFGAIESVIDGGHDPR Mb3748c|M.bovis_AF2122/97 -HVTYTRALGLLGVTDVALIDDAVDALAACDAAALFGAIESVIDGGHDPR MMAR_5240|M.marinum_M -HVTYQRALGLLGATDVALIDDAVDALGAGDAAALFGAVESVIDAGHDPR MUL_4315|M.ulcerans_Agy99 -HVTYQRVLGLLGATDVALIDDAVDALGAGDAAALFGAVESVIDAGHDPR MLBr_02335|M.leprae_Br4923 -HVTYQRALKLLGATDVGLIDDAVDALGAHDAAALFGAVESVIDAGHDPR MAV_0382|M.avium_104 -HVTYQRALGLLGATDLALIDDAVDALAAGDAAALFGAVESVIDAGHDPR MSMEG_6285|M.smegmatis_MC2_155 NHITYQRALSLLGATDLALIDDAVEALAANDAAALFGAVEAVVDAGHDPR MAB_0309|M.abscessus_ATCC_1997 -RVTYQRALSLLGVTDIALIDDAVDALAAGDGAAVFGAIEGVMDAGHDPR TH_1299|M.thermoresistible__bu SRITYQRALGLLGATDVALIDDAVDALAAGDAAALFGAVESVIDSGHDPR :::* *.* ***.**:.***:*::**.* *.**:***:*.*:*.***** Mflv_1281|M.gilvum_PYR-GCK RFATDLLERFRDLIVLQAVPDAVARGVVDGPEDVLERMREQASQLGTATL Mvan_5534|M.vanbaalenii_PYR-1 RFATDLLERFRDLIVLQAVPDAAARGVVDGPEDVLERMREQAARLGTATL Rv3721c|M.tuberculosis_H37Rv RFATDLLERFRDLIVLQSVPDAASRGVVDAPEDALDRMREQAARIGRATL Mb3748c|M.bovis_AF2122/97 RFATDLLERFRDLIVLQSVPDAASRGVVDAPEDALDRMREQAARIGRATL MMAR_5240|M.marinum_M RFATDLLERFRDLIVLQAVPDAVSRGVVDGPEDVLDRMREQAAHLGAATL MUL_4315|M.ulcerans_Agy99 RFATDLLERFRDLIVLQAVPDAVSHGVVDGPEDVLDRMREQAAHLGSATL MLBr_02335|M.leprae_Br4923 RFATDLLERFRDLIVLQAVPDAAARGVVDASEDVLDRMREQAVRIGPATL MAV_0382|M.avium_104 RFATDLLERFRDLILLQAVPDAASRGVVDAPEDVLERMRDQATRIGPATL MSMEG_6285|M.smegmatis_MC2_155 RFATDLLERFRDLIVLQAVPDAVTRGVVDAPTDVLERMREQAERLGAGTL MAB_0309|M.abscessus_ATCC_1997 RFGTDLLERFRDLIVLQAVPDAVERGVVDAPQDVLERMREQAERIGPATL TH_1299|M.thermoresistible__bu RFASDLLERFRDLLILQAVPDAAARGVVDAPGDVLERMREQAARIGAATL **.:*********::**:****. :****.. *.*:***:** ::* .** Mflv_1281|M.gilvum_PYR-GCK TRYAEVVHGGLGEMRGATAPRLLLEVVCARLLLPSASDTEAALLQRVERI Mvan_5534|M.vanbaalenii_PYR-1 TRYAEVVHAGLGEMRGATAPRLLLEVVCARLLLPSASDTEAALLQRVERI Rv3721c|M.tuberculosis_H37Rv TRYAEVVQAGLGEMRGATAPRLLLEVVCARLLLPSASDAESALLQRVERI Mb3748c|M.bovis_AF2122/97 TRYAEVVQAGLGEMRGATAPRLLLEVVCARLLLPSASDAESALLQRVERI MMAR_5240|M.marinum_M TRYAEVVQAGLGEMRGATAPRLLLEVVCARLLLPSASDAESALLQRIERI MUL_4315|M.ulcerans_Agy99 TRYAEVVQAGLGEMRGATAPRLLLEVVCARLLLPSASDAESALLQRIERI MLBr_02335|M.leprae_Br4923 TRYAEVVHSGLGEMRGATAPRLLLEVVCARLLLPSATDAESALLQRVERI MAV_0382|M.avium_104 TRYAEVVQAGLGEMRGATAPRLLLEVVCARLLLPSASDTEAALLQRVERI MSMEG_6285|M.smegmatis_MC2_155 TRYAEVVHAGLGEMRGATAPRLLLEVMCARLLLPSAADTESALLQRIERI MAB_0309|M.abscessus_ATCC_1997 TRYAEVLHAGLGEMRGATAPRLLLEVVCARLLLPSATDAESAVLQRVERI TH_1299|M.thermoresistible__bu TRYAEVVHAGLGEMRGATAPRLLLEVVCARLLLPSASDTESALLHRIERI ******::.*****************:*********:*:*:*:*:*:*** Mflv_1281|M.gilvum_PYR-GCK ETRLDLSIPASDEIVAAGPAVPRKQFVRRSEAAP-----VASPPAEAAPP Mvan_5534|M.vanbaalenii_PYR-1 ETRLDMSIPASDEISASAPAVPRKQFVRKSEAAP-----QPAP---SAQA Rv3721c|M.tuberculosis_H37Rv ETRLDMSIPA-------PQAVPR----PSAAAA----------------- Mb3748c|M.bovis_AF2122/97 ETRLDMSIPA-------PQAVPR----PSAAAA----------------- MMAR_5240|M.marinum_M ETRLAMSIPAG----AGATSAPA----PEAPAAPEAPAAPRATTSARAEA MUL_4315|M.ulcerans_Agy99 ETRLAMSIPAG----AGATSAPA----PEAPAA------PRATTSARAGA MLBr_02335|M.leprae_Br4923 ETRLNMSIPAARAA-YPLQSAPA----EKAAQP----------------- MAV_0382|M.avium_104 ETRLDMSIPAGSTP-AEPVEQPVRFTRPSAAPKP---------------- MSMEG_6285|M.smegmatis_MC2_155 ETRLDMSIPAGEASSGVAPAEPAKQFVRRSQAAAASPP-AAEPAPATPPT MAB_0309|M.abscessus_ATCC_1997 EKRLDMSVPEADG----ASAAPRFVRKSQAAAAP-----AAETAASPAPA TH_1299|M.thermoresistible__bu EKRLDMAVPAT-------DMVPG-----GASAP----------------- *.** :::* * : Mflv_1281|M.gilvum_PYR-GCK PPPAAAPPSAPTPPPAAAPPPRQAEPRPVPAPAPEA-KPVTP-EPDPE-- Mvan_5534|M.vanbaalenii_PYR-1 PAPARAPEPSPEPTPVPAR-----EPDPVPEPPREASKPVEP-EPVPPPL Rv3721c|M.tuberculosis_H37Rv ------------------------EPKHQPAR------------------ Mb3748c|M.bovis_AF2122/97 ------------------------EPKHQPAR------------------ MMAR_5240|M.marinum_M KEMVRQSMRRPAPPEPKSAPERPPAPEPRPAP------------------ MUL_4315|M.ulcerans_Agy99 KEMVRQSMRRPAPPEPKSVPEPPPAPEPRPAP------------------ MLBr_02335|M.leprae_Br4923 ---------------SLPHQPFLASPDSQPAP------------------ MAV_0382|M.avium_104 -------ASKPEPAAAKSEHEPEPQPEARPEP------------------ MSMEG_6285|M.smegmatis_MC2_155 PAAPPTPAAPPAPAVAAPPAPAPAPQAPRPEPPVARPAPEPPPRPAPEPV MAB_0309|M.abscessus_ATCC_1997 PQPPRPAPEPPAPIPGPAPEPPAPRPEPEPAPEPEPAPEPTP-------- TH_1299|M.thermoresistible__bu ---------------------------ARPXX------------------ * Mflv_1281|M.gilvum_PYR-GCK -PPPPMRAPAAPAVEAPPATPAAAVA-----AGEPNAAAVRSMWTTVREK Mvan_5534|M.vanbaalenii_PYR-1 PPPPPVRPPAAPVVEAPATTPAAAVA-----TGEPSAAAVRSMWTTVREK Rv3721c|M.tuberculosis_H37Rv -EPR--------------PVLAPTPA-----SSEPTVAAVRSMWPTVRDK Mb3748c|M.bovis_AF2122/97 -EPR--------------PVLAPTPA-----SSEPTVAAVRSMWPTVRDK MMAR_5240|M.marinum_M -EPRRAPEPRPAPESRPAPVPEPVSA-----PGELNAAAVRSMWPTVREK MUL_4315|M.ulcerans_Agy99 -EPRRAPEPR------PAPVPEPVSA-----PGELNAAAVRSMWPTVREK MLBr_02335|M.leprae_Br4923 -DAQSSKLAT------PQAAAEPTPG-----MGAPNAAAVRTMWSTVREK MAV_0382|M.avium_104 -RPEPTPEPK------PARASETPSA-----PGELNAAAVRSMWSTVRDK MSMEG_6285|M.smegmatis_MC2_155 APPPPAAPVPAAAPAAPAPAAETGSV-----PGQPNAAAVRSMWSTVREK MAB_0309|M.abscessus_ATCC_1997 IPEPPAPEPAPEPEPEPAPVPEPEPAREPRQPGALDTTAVRNAWAEIRAK TH_1299|M.thermoresistible__bu ---XXVQFGAG----VQFGAVVQFNR-----VIQPWVSAKVPRWMPVR-- . .:* * :* Mflv_1281|M.gilvum_PYR-GCK VRERSRTTEVMLAGAIVRAVEGDTLLLTHESAPLARRLCEQRNADVIREA Mvan_5534|M.vanbaalenii_PYR-1 VRERSRTTEVMLAGAIVRAVEGDTLLLSHESAPLAKRLSEQRNADVIREA Rv3721c|M.tuberculosis_H37Rv VRLRSRTTEVMLAGATVRALEDNTLVLTHESAPLARRLSEQRNADVLAEA Mb3748c|M.bovis_AF2122/97 VRLRSRTTEVMLAGATVRALEDNTLVLTHESAPLARRLSEQRNADVLAEA MMAR_5240|M.marinum_M VRQRSRTTEVMLAAATVRALEDNTLVLTHDSAPLARRLSEQRNADVIAEA MUL_4315|M.ulcerans_Agy99 VRQRSRTTEVMLAAATVRALEDNTLVLTHDSAPLARRLSEQRNADVIAEA MLBr_02335|M.leprae_Br4923 VRQRSRTTEVMLAGATVRAVEDNTLILTHGSAPLAKRLSEQHNVDVIAEA MAV_0382|M.avium_104 VRQRSRTTEVMLAGATVRAIEDNTLVLTHESAPLAKRLCEQRNADVIAEA MSMEG_6285|M.smegmatis_MC2_155 VRQRSRTTEVMLSGAIVRAVEGDTLVLSHESAPLAKRLTESRNSEVIREA MAB_0309|M.abscessus_ATCC_1997 VRDRSRTTEVMLSGATVRAIDGNTLVLSHDSPPLAKRITESRNAEVIREA TH_1299|M.thermoresistible__bu ---VSRSAMVTSPGSPSAIVNSPSACLTCDTGVITAAVP-QANTSVISPA **:: * ..: ::. : *: : :: : . * .*: * Mflv_1281|M.gilvum_PYR-GCK LKDALGVNWKIVCEPGVAAAPVPSAP---------------EPVRGGPAE Mvan_5534|M.vanbaalenii_PYR-1 LKDALGVNWKIRCDPGTAPASAAAPA---------------REPQRGPAE Rv3721c|M.tuberculosis_H37Rv LKDALGVNWRVRCETGEPAAAASPVG------------GGANVATAKAVN Mb3748c|M.bovis_AF2122/97 LKDALGVNWRVRCETGEPAAAASPVG------------GGANVATAKAVN MMAR_5240|M.marinum_M LRDALGVNWRVRCEVGAAEPAATPTP------------AKAAAPAADPV- MUL_4315|M.ulcerans_Agy99 LRDALGVNWRVRCEVGAAEPAATPTP------------AKAAAPAADPV- MLBr_02335|M.leprae_Br4923 LKDALGVNWRVRCEAGVPVPAVGALPA---------CEGMVALPTQEKVP MAV_0382|M.avium_104 LKDALGVNWRVRCEAGSPAPATAGPP---------------HPKPEQPVH MSMEG_6285|M.smegmatis_MC2_155 LKDALGVNWKVRCVTGAPEAAVAAPP-----------AATGGAAPQAPAP MAB_0309|M.abscessus_ATCC_1997 LRDALGVNWEIRCDVGSAEAAAPAASRPAKAAPRVVTRPSRPTPDPEPVP TH_1299|M.thermoresistible__bu AAFFCHSSTSILRSSTVKPASVANCS------------------------ . : ... Mflv_1281|M.gilvum_PYR-GCK ---PPPQPDGDDEESMLAE-ASKVDPAAPRRDPEEAALELLQSELGARRI Mvan_5534|M.vanbaalenii_PYR-1 ---PPPPPDIDDEESMLAE-AGNSDPAAPRRDPEEAALELLQNELGARRI Rv3721c|M.tuberculosis_H37Rv PAPTANSTQRDEEEHMLAE-AGRGDPS-PRRDPEEVALELLQNELGARRI Mb3748c|M.bovis_AF2122/97 PAPTANSTQRDEEEHMLAE-AGRGDPS-PRRDPEEVALELLQNELGARRI MMAR_5240|M.marinum_M ---AVDSARREEEESLLAE-AGRSDPSEPRRDPEEVALELLRNELGARRI MUL_4315|M.ulcerans_Agy99 ---AVDSARREEEESLLAE-AGRSDPSEPRRDPEEVALELLRNELGARRI MLBr_02335|M.leprae_Br4923 -VLDVASAQQYEDEGMLAE-PGRRDLSAPRPDLEEVALELLQNELGARRI MAV_0382|M.avium_104 ---EPDSARRDEEEHMLAE-AVR-DEPAARRDPEEAALELLQNELGARRI MSMEG_6285|M.smegmatis_MC2_155 ---DPVEIARAEEDDMLAEAAAEPSESMPRRDPEEVALELLQNELGARRI MAB_0309|M.abscessus_ATCC_1997 EPEPEPPSPEDEEEQMLAE--AGQSEAGPRRDPEEVALELLQNELGARKI TH_1299|M.thermoresistible__bu -----------NESRVMPG--SSEPDSSGVTSRAEPPLPKTKNRFIPPIS ::. ::. . . * .* :..: . Mflv_1281|M.gilvum_PYR-GCK DG-------- Mvan_5534|M.vanbaalenii_PYR-1 DG-------- Rv3721c|M.tuberculosis_H37Rv DNA------- Mb3748c|M.bovis_AF2122/97 DNA------- MMAR_5240|M.marinum_M DNA------- MUL_4315|M.ulcerans_Agy99 DNA------- MLBr_02335|M.leprae_Br4923 DKWLTDAVED MAV_0382|M.avium_104 DGS------- MSMEG_6285|M.smegmatis_MC2_155 DG-------- MAB_0309|M.abscessus_ATCC_1997 DPN------- TH_1299|M.thermoresistible__bu ST-------- .