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MVKFTPDSQTSVLRAGKCSGTLSPSRSRLQRGSWPVDSERRRYGWPRNRRTLAITGAAVVVVVTLAAIGY LIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTT LPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNA KVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTV DRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3524 | - | - | 100% (343) | PROBABLE CONSERVED MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv0931c | pknD | 4e-56 | 45.61% (296) | transmembrane serine/threonine-protein kinase D PKND |
| M. tuberculosis H37Rv | Rv0980c | PE_PGRS18 | 6e-10 | 33.73% (166) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3554 | - | 0.0 | 100.00% (343) | hypothetical protein Mb3554 |
| M. gilvum PYR-GCK | Mflv_1786 | - | 3e-08 | 25.60% (250) | SMP-30/gluconolaconase/LRE domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5012 | - | 3e-91 | 58.11% (296) | hypothetical protein MMAR_5012 |
| M. avium 104 | MAV_4238 | - | 4e-50 | 41.18% (306) | serine/threonine-protein kinase PknD |
| M. smegmatis MC2 155 | MSMEG_5629 | - | 1e-05 | 30.58% (121) | hypothetical protein MSMEG_5629 |
| M. thermoresistible (build 8) | TH_0100 | - | 1e-07 | 27.75% (173) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4817 | - | 1e-10 | 33.84% (198) | hypothetical protein MUL_4817 |
| M. vanbaalenii PYR-1 | Mvan_1720 | - | 2e-10 | 25.09% (279) | YVTN beta-propeller repeat-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 MGSRSAAHGGRSWRSGRHRKQRRIEPYAWLGAGAVTLGIGAAALSGAGIA
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu -----------------------------VTVIGAQQVVDIALAEAARRG
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 AADDPSTDSTSTSSSTEDNTSSDPRTPSSTRSTDAEEPSNDKNIEPPGND
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu KADETMVLVTDRADASLRWAGNSMTTNGESVSRTTTVVSVVRRENSTHVA
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 SDDEADHEVDTTTETDAAARDGADGVDEEPRRNKGREDGIETYDPSPSVD
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu SVRSSEVDPAAIPALVAASQDAALTAPEARDSAPPLPGDTTPDDWDDPVP
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 KQDNDTEANELTAVVDEDDAPRPRGAESQQRPAVGAVSPALTNTQSAPVP
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu GTGVGEFTAIADGLVRGFRGADRLYGYARHIVETTFLATSNGLRRRYTQP
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 LAPHETTTTQLSPETPENATTTRLLDAPTEPFDSPLAWLLLASSRRQIGR
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu TGSVEINAKRDGASAWVGLNAPDFTAVTVDSMLEELSTRLGWARRRVELP
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 VADEDAHSPAADALAVDAENTAPTAALRGQSSPGWFTGRVTGRVAASDVD
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu AGRYETIMPPSTVADMLIYLNWHMDGRGAQEGRTALSAPGGGTRVGEKLT
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 GDRLSFTGMTTAKGTVTVTPWGTFTYRPSKAARHAAAATTASDAEKFDTF
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu DLPLTMYSDPTADGLECLPFVAVPASSDRVSVFDNGLAIGRVDWIRDGVI
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 AITVSDGNGGWTEVPVTVAVRPVNSSPSWLRSTKTKPNPVSGEVNGRIIA
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu NALAYPRAAAEEFHAPVAVPADNLLMTGGTASVRDMVARTERGLLLTTFW
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 IDRDGDAFTYTASAPGKGAVVVNLDGTFSYTASDSARAAARNTWYTDTDR
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu YIRTVDPTTLLVTGLTRDGVYLVEDGEVTAAVNNFRFNESPLDVLRRATE
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 ----------------------MSDNGPAAQVGSWFGPYRLVRLLRQGGM
Mvan_1720|M.vanbaalenii_PYR-1 FIVVVNDGHGGTRSVSVRVEVAPSNNAPTTGAPNLDAPDPGTGAVRGTVN
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu AGASEYTLPREWGDWATRAK-------MPALXXXVRAAALVDILSGQEVS
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 GEVYEAEDTRKHRLVALKLI-------SQQFSGNPEFSARLQREADIAGR
Mvan_1720|M.vanbaalenii_PYR-1 AVDPDGDRITYRRETIMTAKGVLTIGSTGAFNYTPTTAARHAAATSDPNL
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu LFWSKNTIPQRLWPSQGCPAGQRGLLSGLQR-LDNVQPKPADGRTPHPMA
MSMEG_5629|M.smegmatis_MC2_155 ------------------------------------------------MT
MUL_4817|M.ulcerans_Agy99 --------------------------------------------MVRAVI
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 LTEPHVVPIHDYGEIDGRFFVEMRLVDGIDLGSLLHREGPLAPPRAIAII
Mvan_1720|M.vanbaalenii_PYR-1 AADSVTITARDRFGGVGAIVLTIPIAPTNTSPVGSAAGAGVTDPVTGVVR
Mflv_1786|M.gilvum_PYR-GCK -------MNARYAAQN-PTAAEG----------WTLRSVTAPSPLFGANG
TH_0100|M.thermoresistible__bu APMAGAHQQARYTPQNPPGAAPG----------WRLDRITGPSRLFGANG
MSMEG_5629|M.smegmatis_MC2_155 SPISLGNAAPARYTAN-PSVAEG----------WHLRQVTAPSRLFGANG
MUL_4817|M.ulcerans_Agy99 PVTRRLQHAGHYPVTRAPNVAEG----------WTLTRLTAPSRLFGANG
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 RQVAAALDAAHAAGVTHRDVTPG----------NILVTPSDFAYLADFGI
Mvan_1720|M.vanbaalenii_PYR-1 GTVTATDSDGDDLLFSGTTTTEKGSVVVDSIGTYTYTPTTAARHHVNAED
Mflv_1786|M.gilvum_PYR-GCK LRTGPDGRIYIAQVTG-----SQISALDPATGALETVSAKGGDIIAPDDV
TH_0100|M.thermoresistible__bu LRTGPDGRVYIAQVTG-----SQISALDIATGALETISPKGGDIISPDDV
MSMEG_5629|M.smegmatis_MC2_155 LRTGPDGRVYVAQVTG-----SQISALDIVTGELQTVAARGGDIIAPDDV
MUL_4817|M.ulcerans_Agy99 LRTGPDGRVYIAQVTG-----SQISALDLSTGRLDTVCPKGGAIIAPDDL
Rv3524|M.tuberculosis_H37Rv ----------------------------MVKFTPDSQT------------
Mb3554|M.bovis_AF2122/97 ----------------------------MVKFTPDSQT------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 ARAASDPGLTQVGTAI-----GTYYYMAPERFTDDEVTNSVDIYSLACVL
Mvan_1720|M.vanbaalenii_PYR-1 ATDADRRDSFVVTVTDGHGGTAQVLVSVAIAPSSNQAPGGVSYSANPNTD
Mflv_1786|M.gilvum_PYR-GCK AFADDGTLFATEVMDGRVSAREPSGRTRVLRDDLPCANGITVDRGRLFVG
TH_0100|M.thermoresistible__bu AFDPHGNLVATEVMEGRVSLRDTAGRARVLRDDIPSANGITFHRGRLFIG
MSMEG_5629|M.smegmatis_MC2_155 AFDIRGNLYATEVMDGRVSVREPNGTTRVLRDDVPSANGITFHEGRLFIG
MUL_4817|M.ulcerans_Agy99 AFDQDGNLYATEVMDGRVSVRAPDGHTRVLRDDIPSANGITFHQGRLFVG
Rv3524|M.tuberculosis_H37Rv ------------------------------SVLRAG-----------KCS
Mb3554|M.bovis_AF2122/97 ------------------------------SVLRAG-----------KCS
MMAR_5012|M.marinum_M ---------------------------------MAG-----------IGF
MAV_4238|M.avium_104 TECLTGVPPYRADTVERLVAAHLTKTAPPLSQLRPGGFPPALDRVIAKGM
Mvan_1720|M.vanbaalenii_PYR-1 TGVVEGRVTATDPEGDSLTFSGSAETGKGTVAVAPDGSFVYTPTDDARLS
.
Mflv_1786|M.gilvum_PYR-GCK ECRDGGRLMELPLDGGEPRILLENLPSPNAMEVGPDGLLYYPLMTANEIW
TH_0100|M.thermoresistible__bu ECREGGRLLEFSLNGDAPRVLLDNVPSPNAMEVGPDGLLYFPVMGANEIW
MSMEG_5629|M.smegmatis_MC2_155 ECREGGRLLEFDLAGGPPRVLLENVPSPNAMEVGPDGLLYFPVMGANEIW
MUL_4817|M.ulcerans_Agy99 ECRDGGRLLELDLNGGAPRVLARNLPSPNAMEVGPDGLLYFPVMGANEIW
Rv3524|M.tuberculosis_H37Rv GTLSPSRSRLQRGSWPVDSERRRYGWPRNRRTLAITG-------------
Mb3554|M.bovis_AF2122/97 GTLSPSRSRLQRGSWPVDSERRRYGWPRNRRTLAITG-------------
MMAR_5012|M.marinum_M GAS-----------------------PRKWRKLAITG-------------
MAV_4238|M.avium_104 AKRPEDRYRTAGEFAAAAHEALTTSEQRKAATILRDGQIAALGAGAAEQR
Mvan_1720|M.vanbaalenii_PYR-1 AGAPGAPVASKEDSFVVDVSDGHGGTTSISVSVEIVPLIDNESPVAGTPI
:
Mflv_1786|M.gilvum_PYR-GCK RIDPS---GGEPQRVAADLGVPDAVKFDTDG----FIVSTQVASGQVLRI
TH_0100|M.thermoresistible__bu RIDPDQP-GAAPQTVATGLGVPDAVKFDPAG----HIVSTQVATGQVLRI
MSMEG_5629|M.smegmatis_MC2_155 RIHPD---GGTPEVVATGLGVPDAVKFGADG----HLVSTQVASGQVLRI
MUL_4817|M.ulcerans_Agy99 RIDPD---GGVPQCVAGDLRVPDAVKFDPHG----HLVSTQVHSGEVLRI
Rv3524|M.tuberculosis_H37Rv ------------AAVVVV------VTLAAIG----YLIFEPKISGSSTSR
Mb3554|M.bovis_AF2122/97 ------------AAVVVV------VTLAAIG----YLIFEPKISGSSTSR
MMAR_5012|M.marinum_M ------------GAIVVV------AILAVTG----YLIFKP--SGQAPVK
MAV_4238|M.avium_104 STHWPDSFAPSPSAETVVGPSPARAGAPSSG----LIRAAPTGSGRVYAP
Mvan_1720|M.vanbaalenii_PYR-1 VGDPTPGTGVVSGTLGFTDPEGSSLAYTVTGPPAKGLVSIDTTGGFTYTP
* : *
Mflv_1786|M.gilvum_PYR-GCK DPRTG----------EKTVLAQLNPGLDNLTFVGDRLFASNFTGEITEIG
TH_0100|M.thermoresistible__bu DPRTG----------EQTVLATLTPGLDNLTFVGDRLFVSNFTGEITEIL
MSMEG_5629|M.smegmatis_MC2_155 DPRSG----------EQTVLAQLTPGLDNLTFADGRLFVSNFTGAITEIM
MUL_4817|M.ulcerans_Agy99 NPRTG----------DRTVLAALHPGLDNLTFVGERLFVSSFTGEITEIL
Rv3524|M.tuberculosis_H37Rv QAAS------------------------------------PTTPSPPS--
Mb3554|M.bovis_AF2122/97 QAAS------------------------------------PTTPSPPS--
MMAR_5012|M.marinum_M RVDL------------------------------------STAADQPA--
MAV_4238|M.avium_104 GPDFGRPVAPTDNKRKQWIIVGAVALVALVAFVVAVVGYLSTASSGPAKQ
Mvan_1720|M.vanbaalenii_PYR-1 NPEDRPEAGEAPGYDAFTVVATDPQGLAAQVTVDVVVAPLLPPSDGPVVG
. .
Mflv_1786|M.gilvum_PYR-GCK RDGQTSALLPGG--------------------------LNWPLDLTV-SD
TH_0100|M.thermoresistible__bu GDGSTRATLPGG--------------------------LNWPLDLAVGAD
MSMEG_5629|M.smegmatis_MC2_155 GDGTTRDFLGGG--------------------------LNWPLDLTVGAD
MUL_4817|M.ulcerans_Agy99 GTGETRTTLPGG--------------------------LTWPLGLAVAAD
Rv3524|M.tuberculosis_H37Rv ---QVVVPID----------------------------LWNPDGVTVDLA
Mb3554|M.bovis_AF2122/97 ---QVVVPID----------------------------LWNPDGVTVDLA
MMAR_5012|M.marinum_M ---QIKLHFH----------------------------LADPDGVALDSF
MAV_4238|M.avium_104 AGGQSVLPFNGID------------------------FRLSPGGVTLDGA
Mvan_1720|M.vanbaalenii_PYR-1 TPPYDIDSVDEVTGVISGHVTAYTSNGTALTFAVAESPDVASGRVALDSA
. . :::
Mflv_1786|M.gilvum_PYR-GCK GRLYVADGTYFYRVGPDGALETVGMLFSPGYPGF----------------
TH_0100|M.thermoresistible__bu GALYVADGTYFYAVRPDGSLQTVGMLFSSGYPGF----------------
MSMEG_5629|M.smegmatis_MC2_155 GAVYVADGTYFYRVGPDGSLDTVGMLFSPGYPGF----------------
MUL_4817|M.ulcerans_Agy99 GDLYIADGTYFYVLLADGTLRVGGMLFSAGYPGF----------------
Rv3524|M.tuberculosis_H37Rv DAVYVADSGHK-RLLKLPAGSNTPTTLPFTDTIG----------------
Mb3554|M.bovis_AF2122/97 DAVYVADSGHK-RLLKLPAGSNTPTTLPFTDTIG----------------
MMAR_5012|M.marinum_M DTVYVADSGNM-LVQKLPAGSNTPSAFPISAKIV----------------
MAV_4238|M.avium_104 GNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQ----------------
Mvan_1720|M.vanbaalenii_PYR-1 TGRWTFTPTASTLVSAWSSDTPTPVTFTIRVSDGEKSTDITVSATVSPSE
: : : :.
Mflv_1786|M.gilvum_PYR-GCK -------------LRGVVAVGGD-EFVVTTSGGQVARYRPGAG-ETDFLA
TH_0100|M.thermoresistible__bu -------------IRGVEPSGPG-EFVVTTSGGQVTRYRPADS-ESEVLA
MSMEG_5629|M.smegmatis_MC2_155 -------------LRGVIAGGAG-EFIVTTAADTVARYRPGSD-ESEPLA
MUL_4817|M.ulcerans_Agy99 -------------LRGVAALGSG-EFAVTTSNGEVARYRPWAS-ETEVLA
Rv3524|M.tuberculosis_H37Rv -------------PGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPF
Mb3554|M.bovis_AF2122/97 -------------PGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPF
MMAR_5012|M.marinum_M -------------PGGVAVDRHNAVYVIDAAANRVLKVPPDSTIPIELPF
MAV_4238|M.avium_104 -------------PQGLAVDGAGTVYVADFN-NRVLSMAAGSNSQKELPF
Mvan_1720|M.vanbaalenii_PYR-1 QAVINSVEYLGSEPSGVTVGPDGRMYVIDSGANTLSIINPADASMITVTV
*: : : .
Mflv_1786|M.gilvum_PYR-GCK TD------------------------------------------------
TH_0100|M.thermoresistible__bu DG------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 AG------------------------------------------------
MUL_4817|M.ulcerans_Agy99 TG------------------------------------------------
Rv3524|M.tuberculosis_H37Rv GS------------------------------------------------
Mb3554|M.bovis_AF2122/97 GS------------------------------------------------
MMAR_5012|M.marinum_M TG------------------------------------------------
MAV_4238|M.avium_104 SG------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 GKNPTSVASDDLGRLWVTNSGDHTVTVLNAEAEILRTVQVGLVPASVVIR
Mflv_1786|M.gilvum_PYR-GCK ------------------------------FDQLYGVDVAGDGSIVFAEL
TH_0100|M.thermoresistible__bu ------------------------------LDQLYGLALAGDGTVVCAEQ
MSMEG_5629|M.smegmatis_MC2_155 ------------------------------VDQPYGVALAPDGTVVVVEQ
MUL_4817|M.ulcerans_Agy99 ------------------------------LDQLYGVAVAGSGALFVAER
Rv3524|M.tuberculosis_H37Rv ------------------------------LGDAHGLAVDRSDSVYVVDY
Mb3554|M.bovis_AF2122/97 ------------------------------LGDAHGLAVDRSDSVYVVDY
MMAR_5012|M.marinum_M ------------------------------LADPHGLAFDSADTCYVVDH
MAV_4238|M.avium_104 ------------------------------LNYPEGVAVDSQGGVYVADR
Mvan_1720|M.vanbaalenii_PYR-1 GDLAYIANFGGNSLSVIDAADDYSVRSVDVGTNPIDIAIGSDGRIYVANF
.: . . .:
Mflv_1786|M.gilvum_PYR-GCK GTGRVLRLDDGR---VETLASGLRQPVGVAIDADGAPLVSESGAGRVVRV
TH_0100|M.thermoresistible__bu GTGRLLAVRGGE---VEVLATGLTQPVGVALDPDGTPLVAESGAGRIVRV
MSMEG_5629|M.smegmatis_MC2_155 GAGRLLAVRPGS---VDVLADGLDTPVGVAIGPDGAPLVSVAGA--VVRV
MUL_4817|M.ulcerans_Agy99 GAGRVLSVRPDG---VEVMASGLSDPVGVAVTADGRCVVTEADAGRVRTL
Rv3524|M.tuberculosis_H37Rv DNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVAL
Mb3554|M.bovis_AF2122/97 DNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVAL
MMAR_5012|M.marinum_M VNNNVLKLPAGSSTPSELGFTGLDRPYDVAADNADTVYVTDSGHNRVVAL
MAV_4238|M.avium_104 GNSRVLKLAAGSQNQTVLPFTGLNNPDGVAVDPAGNVYVADTDNNRVVKL
Mvan_1720|M.vanbaalenii_PYR-1 GNGTISVLRPDDMDDVLLVDSGGEHPHGILVDDDGTVYVTHPLDDTVTVL
: : . * * .: . *: . : :
Mflv_1786|M.gilvum_PYR-GCK SS-------------------GAVDTVIDGLQRPQGLHVR-DNRLYIVDA
TH_0100|M.thermoresistible__bu AG-------------------GRTDTVVDQLSCPQGILVR-GNQLYIVDA
MSMEG_5629|M.smegmatis_MC2_155 TG-------------------TGVERLVDGLHTPQGLLVR-DGALYLVDA
MUL_4817|M.ulcerans_Agy99 G---------------------DTGTLLDGLQCPQGVAIC-DRQVYVIDS
Rv3524|M.tuberculosis_H37Rv TAGSA----------------TPVHLPFADLSFPAGVTVDRDDSVYVADL
Mb3554|M.bovis_AF2122/97 TAGSA----------------TPVHLPFADLSFPAGVTVDRDDSVYVADL
MMAR_5012|M.marinum_M AAGAT----------------QPVDLPFTGLNFPAGVTVDLSGNVYVADL
MAV_4238|M.avium_104 DAASN----------------TQSELPFHDLSVPWGIAVDNGGTVYVTEH
Mvan_1720|M.vanbaalenii_PYR-1 NPAPVNRFSLRSLFSADATSGQYTYRSVTVIGAPTKITKDTAGRIYVTNS
. : * : :*: :
Mflv_1786|M.gilvum_PYR-GCK GAKELVEFDLGTKARSTIATGLP----------------VGPPPGVEPKP
TH_0100|M.thermoresistible__bu TAKELLAVDLATGQRQRIATGLP----------------VGSPPGVQPKP
MSMEG_5629|M.smegmatis_MC2_155 GSKDLISVDLTTGVRTTIASGLP----------------VGPPPGVVPKP
MUL_4817|M.ulcerans_Agy99 GAKQLVAVDLGSRTRHTIAWDLP----------------VGAPAGVTPNP
Rv3524|M.tuberculosis_H37Rv NNNRVLKLAAGSNAQS----------------------------------
Mb3554|M.bovis_AF2122/97 NNNRVLKLAAGSNAQS----------------------------------
MMAR_5012|M.marinum_M NNNRVVRMDAATHEQS----------------------------------
MAV_4238|M.avium_104 DKNDVVKYPPGATSGT----------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 SGATITVLDPLTLAANEIHTGANPSSVYVDRFGNLYVTNAGQKTVAVIHA
: :
Mflv_1786|M.gilvum_PYR-GCK LKGMPPFSGPQGPFAGITSGPDGTLFVSADGDGSVLAVSRG---------
TH_0100|M.thermoresistible__bu LKGMPPFSGPQGPFAGITAGPDGTLYLSADGDGSVLALRRTR--------
MSMEG_5629|M.smegmatis_MC2_155 LKGMPPFSGPQGPFAGIAAGPDGTLYISADGDGSVLALQRR---------
MUL_4817|M.ulcerans_Agy99 LRGMPPFSGPEGPFAAITPGPDATLYISADADGSVLALRRES--------
Rv3524|M.tuberculosis_H37Rv ---QLPFTGLFSPTD-VAVDNDGAVYVIDFYN-RMLKLPTA---------
Mb3554|M.bovis_AF2122/97 ---QLPFTGLFSPTD-VAVDNDGAVYVIDFYN-RMLKLPTA---------
MMAR_5012|M.marinum_M ---VLPFKDLFSPTD-VAVDSQGSVYVIDYRD-RVLKLPAQSNSRHAR--
MAV_4238|M.avium_104 ---VLPFTALNTPLA-VAVDRDQSVYVADRGDDRVVKLAQ----------
Mvan_1720|M.vanbaalenii_PYR-1 QTRNITTYRADVKTSQVTTDDDGNLVMVSTYDGHRSVLSTDTVSTGADAL
. :: . : : : : :
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 QIANVWGSYGSLVASPDGKWLYAVRNRRVDTTGGLYPNRYDIVAIDTSNN
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 SVRTFAWDAHINGSMVLTMNRDGDRLYAAYYTLDPEVFDGVVAKVAIINV
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 DGSTLQLDGAPVELNLGSTTAFVSDIVVNPAGTKVFVIGDRLAVPGQWDA
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 PEGQWNMYGNLWMVDLENDRAVSRPPIPRPLQAEGGVPDLAISPDGRYAY
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 LVMTPLPGWEGNHYLGIFDTQSFALTTVLLGHFEAPNGVRRLVVSPDGTR
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 IYLSDGQIVGVTGTQHELLEDRIQGIDQERFVDIAINPEGTRLYTTTWDG
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 VLTTIDTSTGLPVGNPTDLGNRAWGMTFGPKGDTLYVRRGVDYVASHRAP
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 QSIADLWENVRDLPNGDNEGIFTQVVRHADGTNRMVVYLGGTNPRNWLVG
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 EQAIGENVVSELGILKDEHLGAITRALAHCRNDATCGDIADVMLVGFSQG
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 GIDGQNFASQWDRLGFGVQLSALVTFGSPITKNPNVPTLHIQDIDDEVVN
Mflv_1786|M.gilvum_PYR-GCK --------------------------------------------------
TH_0100|M.thermoresistible__bu --------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4817|M.ulcerans_Agy99 --------------------------------------------------
Rv3524|M.tuberculosis_H37Rv --------------------------------------------------
Mb3554|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5012|M.marinum_M --------------------------------------------------
MAV_4238|M.avium_104 --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 TELLARLAATVQYVPMPSWLRINFAAATVTAMARGQLYQGAADTDISVLD
Mflv_1786|M.gilvum_PYR-GCK -------------------------------------------------
TH_0100|M.thermoresistible__bu -------------------------------------------------
MSMEG_5629|M.smegmatis_MC2_155 -------------------------------------------------
MUL_4817|M.ulcerans_Agy99 -------------------------------------------------
Rv3524|M.tuberculosis_H37Rv -------------------------------------------------
Mb3554|M.bovis_AF2122/97 -------------------------------------------------
MMAR_5012|M.marinum_M -------------------------------------------------
MAV_4238|M.avium_104 -------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1 IFAVHGNRATYQQLASEMDARTGTDFAALGPVRTFFGGTALIPGDPTPL