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M. tuberculosis H37Rv Rv3500c (yrbE4B)

annotation: CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4B
coordinates: 3919220 - 3920062
length: 280

SYDVTIRFRRFFSRLQRPVDNFGEQALFYGETMRYVPNAITRYRKETVRLVAEMTLGAGALVMIGGTVGV
AAFLTLASGGVIAVQGYSSLGDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLGAMRVSEE
IDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLSVLAAFFAARFTTVFVNGQSAGLYDHYFNTFLIPSDL
LWSFMQAIAMSIAVMLVHTYYGYNASGGSVGVGVAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv3500c yrbE4B - 100% (280) CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4B
M. tuberculosis H37Rv Rv0168 yrbE1B 9e-81 50.37% (270) integral membrane protein YRBE1B
M. tuberculosis H37Rv Rv0588 yrbE2B 4e-79 51.67% (269) integral membrane protein YrbE2b

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3530c yrbE4B 1e-153 100.00% (280) integral membrane protein YrbE4b
M. gilvum PYR-GCK Mflv_1555 - 1e-137 87.14% (280) hypothetical protein Mflv_1555
M. leprae Br4923 MLBr_02588 yrbE1B 1e-81 50.19% (269) hypothetical protein MLBr_02588
M. abscessus ATCC 19977 MAB_4154c - 1e-123 78.14% (279) hypothetical protein MAB_4154c
M. marinum M MMAR_4988 yrbE4B 1e-148 95.71% (280) membrane protein YrbE4B
M. avium 104 MAV_0656 - 1e-145 92.50% (280) ABC-transporter integral membrane protein
M. smegmatis MC2 155 MSMEG_5901 - 1e-139 89.29% (280) TrnB2 protein
M. thermoresistible (build 8) TH_1938 - 1e-136 86.07% (280) CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4B
M. ulcerans Agy99 MUL_4063 yrbE4B 1e-147 94.29% (280) membrane protein YrbE4B
M. vanbaalenii PYR-1 Mvan_5203 - 1e-137 87.86% (280) hypothetical protein Mvan_5203

CLUSTAL 2.0.9 multiple sequence alignment


Rv3500c|M.tuberculosis_H37Rv        -------MSYDVTIR---------FRRFFSRLQRPVDNFGEQALFYGETM
Mb3530c|M.bovis_AF2122/97           -------MSYDVTIR---------FRRFFSRLQRPVDNFGEQALFYGETM
MMAR_4988|M.marinum_M               -------MSYDVTIR---------FHRFMSRLVRPVDNFGEQALFYGETV
MUL_4063|M.ulcerans_Agy99           -------MSYDLTVR---------FHRFMSRLARPVDNLGEQALFYGETV
MAV_0656|M.avium_104                -------MSYDATLR---------FRRWFSRLQEPVDDFGEQALFYGQTM
Mflv_1555|M.gilvum_PYR-GCK          -------MSYDATVR---------FRRMLRVFPRAVDTVGEQALFYGETF
Mvan_5203|M.vanbaalenii_PYR-1       -------MSYDATIR---------FRRLLRFFPRAVDTVGEQALFYGETF
MSMEG_5901|M.smegmatis_MC2_155      MRKKEKPMSYDATLR---------FRRLFRGVPKTVDTVGEQALFYGETM
TH_1938|M.thermoresistible__bu      -------MSYDVTLR---------LRRAFRMVPKAVDAFGEQALFYGETV
MAB_4154c|M.abscessus_ATCC_199      -MSGPYLSTHTVTSY---------TVRYMRGLGRSFDKFGEQALFYAQSL
MLBr_02588|M.leprae_Br4923          -------MSTAAVLRARFPRAAANLNRYGGAAARGIDDIGQMSWFGLIAL
                                            :   .             *      . .* .*: : *   :.

Rv3500c|M.tuberculosis_H37Rv        RYVPNAITRYRKETVRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIA
Mb3530c|M.bovis_AF2122/97           RYVPNAITRYRKETVRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIA
MMAR_4988|M.marinum_M               RYIPNAITRYRKETIRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIA
MUL_4063|M.ulcerans_Agy99           RYIPNATTRYRKETIRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIA
MAV_0656|M.avium_104                RYVPNALTRYRKETIRLIAEMTMGAGALVMIGGTVGVAAFLTLASGGVIA
Mflv_1555|M.gilvum_PYR-GCK          RYVPNAITRYRKETIRLIAEMSMGTGALVMIGGTVGVAAFMTLASGGVIA
Mvan_5203|M.vanbaalenii_PYR-1       RYVPNALTRYRKETIRLIAEMSMGTGALVMIGGTVGVAAFMTLASGGVIA
MSMEG_5901|M.smegmatis_MC2_155      RYLPNAFTRYRKETIRLVAEMTMGAGALVMIGGTVGVAAFLTLASGGVIA
TH_1938|M.thermoresistible__bu      RYIPNAVTKYRKETIRLVAEMTLGTGALVIIGGTVGVAAFLTLASGGVVA
MAB_4154c|M.abscessus_ATCC_199      SYIPAALTKYRKETIRVLAEITMGTGALVMIGGTVGVAVFLTLASGGVIA
MLBr_02588|M.leprae_Br4923          GNIPNALSRYRKETLRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGSSLVA
                                      :* * ::*****:*::*:: :*:**:.::***..:. *:**:...::*

Rv3500c|M.tuberculosis_H37Rv        VQGYSSLGDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLG
Mb3530c|M.bovis_AF2122/97           VQGYSSLGDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLG
MMAR_4988|M.marinum_M               VQGYSSLGDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLG
MUL_4063|M.ulcerans_Agy99           VQGYSSLGDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLG
MAV_0656|M.avium_104                VQGYSSLGNIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLG
Mflv_1555|M.gilvum_PYR-GCK          VQGYSSLGNIGIEALTGFLSAFLNVRIVAPVIAGIALAATIGAGATAQLG
Mvan_5203|M.vanbaalenii_PYR-1       VQGYSSLGNIGIEALTGFLSAFLNVRIVAPVIAGIALAATIGAGATAQLG
MSMEG_5901|M.smegmatis_MC2_155      VQGYSSLGNIGIEALTGFLSAFLNVRIVAPVIAGIALAATIGAGATAQLG
TH_1938|M.thermoresistible__bu      VQGYDSLGNIGIEALTGFLSAFLNVRIIAPVIAGIALAATIGAGTTAQLG
MAB_4154c|M.abscessus_ATCC_199      VQGYSSLGNIGIEALTGFLSAFLNVRIVAPVVAGIAMAATIGAGTTAQLG
MLBr_02588|M.leprae_Br4923          IQGFASLGAIGVEAFTGFFAALINVRIAAPVITGIVMAATVGAGATAELG
                                    :**: *** **:**:***::*::***: ***::**.:***:***:**:**

Rv3500c|M.tuberculosis_H37Rv        AMRVSEEIDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLSVLAAFFAAR
Mb3530c|M.bovis_AF2122/97           AMRVSEEIDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLSVLAAFFAAR
MMAR_4988|M.marinum_M               AMRVSEEIDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLAVLAAFFAAR
MUL_4063|M.ulcerans_Agy99           AMRVSEEIDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLAVLAAFFAAR
MAV_0656|M.avium_104                AMRVSEEIDAVECMAVHSVSYLVSTRLIAGLIAIVPLYSLSVLAAFFAAR
Mflv_1555|M.gilvum_PYR-GCK          AMRVAEEIDAVEAMAVHAVSYLVSTRLIAGLIAIVPLYALSVLAAFFAAR
Mvan_5203|M.vanbaalenii_PYR-1       AMRVAEEIDAVESMAVHAVSYLVSTRLIAGLIAIVPLYALSVLAAFFAAR
MSMEG_5901|M.smegmatis_MC2_155      AMRVAEEIDAVESMAVHAVSYLVSTRLLAGLIAIVPLYSLSVLAAFFAAR
TH_1938|M.thermoresistible__bu      AMRVAEEIDAVESMAVHSVSYLVSTRLIAGLIAIVPLYSLSVLAAFFAAR
MAB_4154c|M.abscessus_ATCC_199      AMRVAEEIDALETMAVHAISYLVSTRLVAGLIAIIPLYSLSVLAAFFASR
MLBr_02588|M.leprae_Br4923          AMRISEEIDALEVMSIKSISFLVTTRILAGLVVIVPLYAVAMIMAFLSPH
                                    ***::*****:* *:::::*:**:**::***:.*:***::::: **::.:

Rv3500c|M.tuberculosis_H37Rv        FTTVFVNGQSAGLYDHYFNTFLIPSDLLWSFMQAIAMSIAVMLVHTYYGY
Mb3530c|M.bovis_AF2122/97           FTTVFVNGQSAGLYDHYFNTFLIPSDLLWSFMQAIAMSIAVMLVHTYYGY
MMAR_4988|M.marinum_M               FTTVFINGQSAGLYDHYFNTFLIPSDLLWSFLQAIVMAIAVMLVHTYYGY
MUL_4063|M.ulcerans_Agy99           FTTVFINGQSAGLYDHYFNTFLIPSDLLWSFLQAIVMAIAVMLVHTYYGY
MAV_0656|M.avium_104                FTTVYINGQSKGLYDHYFNTFLIPSDLLWSFLQAIVMSIAVMLVHTYYGY
Mflv_1555|M.gilvum_PYR-GCK          FTTVYINGQSAGLYDHYFNTFLVPSDLLWSFLQAIVMSIAVMLVHTYYGY
Mvan_5203|M.vanbaalenii_PYR-1       FTTVYINGQSAGLYDHYFNTFLIPSDLLWSFLQAIVMSIAVMLVHTYYGY
MSMEG_5901|M.smegmatis_MC2_155      FTTVFINGQSAGLYDHYFNTFLIPSDLLWSFLQAIVMAIAVMLVHTYYGY
TH_1938|M.thermoresistible__bu      FTTVYINGQSGGLYDHYFNTFLNPDDLLWSFLQAIVMAVAVMLVHTYYGY
MAB_4154c|M.abscessus_ATCC_199      ATTVMINGQSPGVYDHYFNTFLVPTDLLWSFLQAIVMSVVVMLVHTSYGF
MLBr_02588|M.leprae_Br4923          IITTVLYGQSNGTYEHYFRTFLRPDDVFWSFLEAVIITAVVMITHCYYGY
                                      *. : *** * *:***.*** * *::***::*: :: .**:.*  **:

Rv3500c|M.tuberculosis_H37Rv        NASGGSVGVGVAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
Mb3530c|M.bovis_AF2122/97           NASGGSVGVGVAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
MMAR_4988|M.marinum_M               NASGGSVGVGIAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
MUL_4063|M.ulcerans_Agy99           NASGGSVGVGIAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
MAV_0656|M.avium_104                NAHGGPVGVGIAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
Mflv_1555|M.gilvum_PYR-GCK          NASGGPVGVGIAVGQAVRTSLIVVVTIVLMISLAVYGASGNFNLSG
Mvan_5203|M.vanbaalenii_PYR-1       NASGGPVGVGIAVGQAVRTSLIVVVTIVLFISLAVYGASGNFNLSG
MSMEG_5901|M.smegmatis_MC2_155      NASGGPVGVGIAVGQAVRTSLIVVVTITLFISLAVYGASGNFNLSG
TH_1938|M.thermoresistible__bu      NASGGPVGVGIAVGQAVRTSLIVVVVLTLFISLAVYGASGNFNLSG
MAB_4154c|M.abscessus_ATCC_199      NASGGPVGVGVAVGQAVRTSLIVVVLVTLFISLAVYGGSGNFNLSG
MLBr_02588|M.leprae_Br4923          TANGGPVGVGEAVGRSMRFSLVSVQVVVLSATLALYGVDPNFALTV
                                    .* **.**** ***:::* **: *  :.*  :**:** . ** *:

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv3500c	yrbE4B	-	100% (280)	CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4B
M. tuberculosis H37Rv	Rv0168	yrbE1B	9e-81	50.37% (270)	integral membrane protein YRBE1B
M. tuberculosis H37Rv	Rv0588	yrbE2B	4e-79	51.67% (269)	integral membrane protein YrbE2b