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MREFQRAAVRLHILHHAADNEVHGAWLTQELSRHGYRVSPGTLYPTLHRLEADGLLVSEQRVVDGRARRV YRATPAGRAALTEDRRALEELAREVLGGQSHTAGNGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3488 | - | - | 100% (107) | hypothetical protein Rv3488 |
| M. tuberculosis H37Rv | Rv0047c | - | 4e-05 | 37.80% (82) | hypothetical protein Rv0047c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3518 | - | 2e-57 | 99.07% (107) | hypothetical protein Mb3518 |
| M. gilvum PYR-GCK | Mflv_1330 | - | 4e-07 | 37.97% (79) | PadR-like family transcriptional regulator |
| M. leprae Br4923 | MLBr_02313 | - | 3e-05 | 31.65% (79) | hypothetical protein MLBr_02313 |
| M. abscessus ATCC 19977 | MAB_0383c | - | 3e-06 | 34.18% (79) | putative transcriptional regulator, PadR-like |
| M. marinum M | MMAR_4976 | - | 8e-48 | 91.75% (97) | hypothetical protein MMAR_4976 |
| M. avium 104 | MAV_0407 | - | 2e-05 | 34.18% (79) | transcriptional regulator, PadR family protein |
| M. smegmatis MC2 155 | MSMEG_6227 | - | 3e-06 | 35.37% (82) | transcriptional regulator, PadR family protein |
| M. thermoresistible (build 8) | TH_1310 | - | 2e-07 | 42.17% (83) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4050 | - | 1e-48 | 91.75% (97) | hypothetical protein MUL_4050 |
| M. vanbaalenii PYR-1 | Mvan_6039 | - | 5e-07 | 41.33% (75) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3488|M.tuberculosis_H37Rv --------------------------------------------------
Mb3518|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4976|M.marinum_M --------------------------------------------------
MUL_4050|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02313|M.leprae_Br4923 -MASASQTQRITN-----MNDPFLPPNGPFAAEPSLGFGFSPG-------
MAV_0407|M.avium_104 MFRSARPVRKPTNVRTKTMSNPFTPPDGPFGARPGFGFGFGPGRVDRRAL
Mflv_1330|M.gilvum_PYR-GCK ------------------MTSPFTPPDNPFERR-GFGFGFGPVDR--RAL
MSMEG_6227|M.smegmatis_MC2_155 ------------------MSTPFAFPTG--------DFGFGPAGR--RAM
MAB_0383c|M.abscessus_ATCC_199 -MTSHEER-----------AEQFR-PDTPFG----FGFGFDPTGRG-PGL
TH_1310|M.thermoresistible__bu --------------------------------------------------
Mvan_6039|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3488|M.tuberculosis_H37Rv --------------------------------------------------
Mb3518|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4976|M.marinum_M --------------------------------------------------
MUL_4050|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02313|M.leprae_Br4923 ----------------------------------------P---------
MAV_0407|M.avium_104 HEARRQARRDFREHLREHA-----------GGHDGPLGFGPGFGPG----
Mflv_1330|M.gilvum_PYR-GCK HERRRHARREFRDHVREHRGDA---AFGPGFGGFGPGGFGPGGGGF----
MSMEG_6227|M.smegmatis_MC2_155 LHHRRAARREFRDQMRAHLHEAREQALDPRCEMGGPGGPGPMGGPGRGFG
MAB_0383c|M.abscessus_ATCC_199 RGRRHGSRRHECDPRGEFHEQAWAGRRGP--GAFMDRGFGPG--------
TH_1310|M.thermoresistible__bu --------------------------------------------------
Mvan_6039|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3488|M.tuberculosis_H37Rv ----------------------------MREFQRAAVRLHILHHAADNEV
Mb3518|M.bovis_AF2122/97 ----------------------------MREFQRAAVRLHILHHAADNEV
MMAR_4976|M.marinum_M ----------------------------MREFQRAAVRLHILHHAADDEV
MUL_4050|M.ulcerans_Agy99 ----------------------------MREFQRAAVRLHILHHAADDEV
MLBr_02313|M.leprae_Br4923 ----GPEFS--FSFGP------RRRGDA-GRGRRGDVRAAILMLLTERPM
MAV_0407|M.avium_104 ---FGPAFGPGFGFGPGGPRGAWRRGGP-GRGKRGDVRAAVLALLAERPM
Mflv_1330|M.gilvum_PYR-GCK ---GPGSFGPGFGFGPG----SRRGGGPRGRSRRGDVRAAILTLLTDRPM
MSMEG_6227|M.smegmatis_MC2_155 GFGFGFDPGAGFGFGPGGPR-GRRGHGRGRRGRRGDVRAAILKLLAERPM
MAB_0383c|M.abscessus_ATCC_199 ---FGRGFGPGFGFGFG----EQPRGRGRGRGQRGDVRAAILALLAERPM
TH_1310|M.thermoresistible__bu --------------------------------VIRLLELAILGLLLESPM
Mvan_6039|M.vanbaalenii_PYR-1 -----------------------------------MLELAILGLLQESPM
:. :* : :
Rv3488|M.tuberculosis_H37Rv HGAWLTQELSRHG---YRVSPGTLYPTLHRLEADGLLVSEQRVV----DG
Mb3518|M.bovis_AF2122/97 HGAWLTQELSRHG---YRVSPGTLYPTLHRLEADGLLVSEQRVV----DG
MMAR_4976|M.marinum_M HGAWLTEELSRHG---YKVSPGTLYPTLHRLEADGLLLSEQRVV----DG
MUL_4050|M.ulcerans_Agy99 HGAWLTEELSRHG---YKVNPGTLYPTLHRLEADGLLLSEQRVV----DG
MLBr_02313|M.leprae_Br4923 HGYQMIQQIAERSNGIWRPSPGSVYPTLQLLSDKNLITASA-------TD
MAV_0407|M.avium_104 HGYEMIQLIAERSNGLWKPSPGSVYPTLQLLADEGLITATE-------TD
Mflv_1330|M.gilvum_PYR-GCK HGYEMIQEINERSRQMWKPSPGSVYPTLQLLVDEGLIVSTE-------AE
MSMEG_6227|M.smegmatis_MC2_155 HGYEMIQEIGERTDNLWRPSPGSVYPTLQLLVDEGLISGTE-------AE
MAB_0383c|M.abscessus_ATCC_199 HGYEMIREIAERSNNIWRPSPGSVYPTLQLLVDEGLITETE-------GG
TH_1310|M.thermoresistible__bu HGYELRKRLTGLLGAFRAFSYGSLYPALRRMQADGLIVEDPAPDGTPKVR
Mvan_6039|M.vanbaalenii_PYR-1 HGYELRKRLTGLLGAFRAFSYGSLYPALRRMQADGLIVEDAAPEGTVKVR
** : . : . *::**:*: : ..*:
Rv3488|M.tuberculosis_H37Rv RARRVYRATPAGR------------------------AALTEDRR-----
Mb3518|M.bovis_AF2122/97 RARRVYRATPAGR------------------------AALTEDRR-----
MMAR_4976|M.marinum_M RTRRVYRATSAGR------------------------AALTEDRR-----
MUL_4050|M.ulcerans_Agy99 RTRRVYRATPAGR------------------------AALTEDRR-----
MLBr_02313|M.leprae_Br4923 GSKKLFELTDDGR------------------------AAAAKVEMPPWDQ
MAV_0407|M.avium_104 GSKKLFELTDDGR------------------------AAAEKIETPPWDE
Mflv_1330|M.gilvum_PYR-GCK GSKKLFELTDDGR------------------------AAAEKIDTAPWDA
MSMEG_6227|M.smegmatis_MC2_155 GSKKLFELTEAGR------------------------AAAEAIETPPWEQ
MAB_0383c|M.abscessus_ATCC_199 SSRKQFELTEEGT------------------------AAAEKLDTPPWEK
TH_1310|M.thermoresistible__bu RARRVYRLTEAGKQRFTELVADTGPQNYSDDGFGVHLAFFNRTPAEARMR
Mvan_6039|M.vanbaalenii_PYR-1 RARRVYQLTDAGKQRFTELVADTGPQNYSDDGFGVHLAFFNRTPAEARMR
::: :. * * *
Rv3488|M.tuberculosis_H37Rv ----------ALEELAREVLGGQSHTAGNGT-------------------
Mb3518|M.bovis_AF2122/97 ----------ALEELAREVLGRQSHTAGNGT-------------------
MMAR_4976|M.marinum_M ----------ALRELAREVLGSDL--------------------------
MUL_4050|M.ulcerans_Agy99 ----------ALRELAREVLGSDL--------------------------
MLBr_02313|M.leprae_Br4923 IAQGINPGYINLRTAMNQLFGAVTQSAHTASADQQQRIIDTINNARREIY
MAV_0407|M.avium_104 IAEGADPGHMNLRAAIGQLFGAVGQSAHTASPEQQQRIVDILNNARREIY
Mflv_1330|M.gilvum_PYR-GCK MAEQADPGAVNLRNAAGQLMGAVAQSAHAATPEQQQRILDIVNNARREIY
MSMEG_6227|M.smegmatis_MC2_155 IAEDVDPAAVNLRGAIAQLMGAVAQSAYTATEDQQQRILDVVNNARREIY
MAB_0383c|M.abscessus_ATCC_199 INEDADPSVLDLRSALGQLMGAVAQSAHAASPEQQQRIIEIVNSARKQIY
TH_1310|M.thermoresistible__bu ILEGRRRQVEERREGLREAIARASNSFDRYTRQLHQLGLESSEREVNWLN
Mvan_6039|M.vanbaalenii_PYR-1 ILEGRRRQVEERREGLRDAVARASSSFDRYTRQLHQLGLESSEREVKWLN
. : ..
Rv3488|M.tuberculosis_H37Rv ----------------
Mb3518|M.bovis_AF2122/97 ----------------
MMAR_4976|M.marinum_M ----------------
MUL_4050|M.ulcerans_Agy99 ----------------
MLBr_02313|M.leprae_Br4923 GILGEN----------
MAV_0407|M.avium_104 GILGED----------
Mflv_1330|M.gilvum_PYR-GCK SVLGED----------
MSMEG_6227|M.smegmatis_MC2_155 QILGEE----------
MAB_0383c|M.abscessus_ATCC_199 GILGETD---------
TH_1310|M.thermoresistible__bu DLIAAERMAQGRAEQP
Mvan_6039|M.vanbaalenii_PYR-1 ELIAAERSAQGRAEQT