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FRSARPVRKPTNVRTKTMSNPFTPPDGPFGARPGFGFGFGPGRVDRRALHEARRQARRDFREHLREHAGG HDGPLGFGPGFGPGFGPAFGPGFGFGPGGPRGAWRRGGPGRGKRGDVRAAVLALLAERPMHGYEMIQLIA ERSNGLWKPSPGSVYPTLQLLADEGLITATETDGSKKLFELTDDGRAAAEKIETPPWDEIAEGADPGHMN LRAAIGQLFGAVGQSAHTASPEQQQRIVDILNNARREIYGILGED*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0407 | - | - | 100% (256) | transcriptional regulator, PadR family protein |
| M. avium 104 | MAV_0068 | - | 4e-07 | 36.99% (73) | transcriptional regulator, PadR family protein |
| M. avium 104 | MAV_4826 | - | 5e-05 | 37.76% (98) | hypothetical protein MAV_4826 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0048c | - | 2e-06 | 35.62% (73) | hypothetical protein Mb0048c |
| M. gilvum PYR-GCK | Mflv_1330 | - | 1e-95 | 72.18% (248) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0047c | - | 2e-06 | 35.62% (73) | hypothetical protein Rv0047c |
| M. leprae Br4923 | MLBr_02313 | - | 3e-73 | 58.68% (242) | hypothetical protein MLBr_02313 |
| M. abscessus ATCC 19977 | MAB_0383c | - | 2e-75 | 64.29% (238) | putative transcriptional regulator, PadR-like |
| M. marinum M | MMAR_5206 | - | 1e-107 | 76.89% (238) | PadR-like transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6227 | - | 7e-78 | 60.62% (259) | transcriptional regulator, PadR family protein |
| M. thermoresistible (build 8) | TH_1310 | - | 5e-05 | 33.78% (74) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4279 | - | 1e-106 | 76.47% (238) | PadR-like transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5462 | - | 3e-92 | 69.41% (255) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5206|M.marinum_M ---------------------MNNLFTPPGGPFGPRP---GFGFGPGPAQ
MUL_4279|M.ulcerans_Agy99 MYSIYQSSIVATFQKTRKEHNMNNLFTPPGGPFGPRP---GFGFGPGPAQ
MLBr_02313|M.leprae_Br4923 ---------MASASQTQRITNMNDPFLPPNGPFAAEP---SLGFG-----
MAV_0407|M.avium_104 ---MFRSARPVRKPTNVRTKTMSNPFTPPDGPFGARPG-FGFGFGPGRVD
Mflv_1330|M.gilvum_PYR-GCK ---------------------MTSPFTPPDNPFERRG----FGFGFGPVD
Mvan_5462|M.vanbaalenii_PYR-1 ---------------------MNTPFTPPENPFDRRG----FGFGFGPEG
MSMEG_6227|M.smegmatis_MC2_155 ---------------------MSTPFAFPTGDFGFGPAGRRAMLHHRRAA
MAB_0383c|M.abscessus_ATCC_199 ---------------MTSHEERAEQFR-PDTPFG-------FGFGFDPTG
Mb0048c|M.bovis_AF2122/97 ---------------MLELAILGLLIESPMHGYELRKR------------
Rv0047c|M.tuberculosis_H37Rv ---------------MLELAILGLLIESPMHGYELRKR------------
TH_1310|M.thermoresistible__bu ------------VIRLLELAILGLLLESPMHGYELRKR------------
: * :
MMAR_5206|M.marinum_M RRALHSARRHA--RREFFEHLRDHDADHDGPLGFG----GGFGPGFG---
MUL_4279|M.ulcerans_Agy99 RRALHSARRHA--RREFFEHLRDHDADHDGPLGFG----GGFGPGFG---
MLBr_02313|M.leprae_Br4923 -----------------------------------------FSPGPG---
MAV_0407|M.avium_104 RRALHEARRQA--RRDFREHLREHAGGHDGPLGFG----PGFGPGFG---
Mflv_1330|M.gilvum_PYR-GCK RRALHERRRHA--RREFRDHVREHRGDAAFGPGFGGFGPGGFGPGGGGFG
Mvan_5462|M.vanbaalenii_PYR-1 RRTVHERRRQA--RREFHDHIREHRGDAGFGPGPGGFGPGGFGPGFGGFG
MSMEG_6227|M.smegmatis_MC2_155 RREFRDQMRAH--LHEAREQALDPRCEMGGPGGPGP--MGGPGRGFGGFG
MAB_0383c|M.abscessus_ATCC_199 RGPGLRGRRHGSRRHECDPRGEFHEQAWAGRRGPGAFMDRGFGPGFG---
Mb0048c|M.bovis_AF2122/97 --------------------------------------LTGLLGAFR---
Rv0047c|M.tuberculosis_H37Rv --------------------------------------LTGLLGAFR---
TH_1310|M.thermoresistible__bu --------------------------------------LTGLLGAFR---
.
MMAR_5206|M.marinum_M ---PGLG--FGFGPGGARG--GGRRGGPGRGRRGDVRAAILVLLSEQPMH
MUL_4279|M.ulcerans_Agy99 ---PGLG--FGFGPGGARG--GGRRGGPGRGRRGDVRAAILVLLSEQPMH
MLBr_02313|M.leprae_Br4923 ---PEFS--FSFGP--------RRRGDAGRGRRGDVRAAILMLLTERPMH
MAV_0407|M.avium_104 ---PAFGPGFGFGPGGPRG--AWRRGGPGRGKRGDVRAAVLALLAERPMH
Mflv_1330|M.gilvum_PYR-GCK PGS--FGPGFGFGPGSRRG--GGPRG---RSRRGDVRAAILTLLTDRPMH
Mvan_5462|M.vanbaalenii_PYR-1 PGGGKFGPGFGFGPGGRGGRRGGPRGG-GRSRRGDVRAAILKLLTDRPMH
MSMEG_6227|M.smegmatis_MC2_155 FG-FDPGAGFGFGPGGPRG--RRGHGRGRRGRRGDVRAAILKLLAERPMH
MAB_0383c|M.abscessus_ATCC_199 ---RGFGPGFGFGFGEQPR--GRGRG---RGQRGDVRAAILALLAERPMH
Mb0048c|M.bovis_AF2122/97 ----------AFSYGSLYP---ALRRMQADGLIAENAAPAGTP-VRRARR
Rv0047c|M.tuberculosis_H37Rv ----------AFSYGSLYP---ALRRMQADGLIAENAAPAGTP-VRRARR
TH_1310|M.thermoresistible__bu ----------AFSYGSLYP---ALRRMQADGLIVEDPAPDGTPKVRRARR
.*. : . : *. :. :
MMAR_5206|M.marinum_M GYEMIQQIADRSNGLWRPSPGSVYPTLQLLDDEGLIAASASDGSKKLFEL
MUL_4279|M.ulcerans_Agy99 GYEMIQQIADRSNGLWRPSPGSVYPTLQLLDDEGLIAASASDASKKLFEL
MLBr_02313|M.leprae_Br4923 GYQMIQQIAERSNGIWRPSPGSVYPTLQLLSDKNLITASATDGSKKLFEL
MAV_0407|M.avium_104 GYEMIQLIAERSNGLWKPSPGSVYPTLQLLADEGLITATETDGSKKLFEL
Mflv_1330|M.gilvum_PYR-GCK GYEMIQEINERSRQMWKPSPGSVYPTLQLLVDEGLIVSTEAEGSKKLFEL
Mvan_5462|M.vanbaalenii_PYR-1 GYEMIQEINDRSQQLWKPSPGSIYPTLQLLVDEGLLTAAETEGSKKLFEL
MSMEG_6227|M.smegmatis_MC2_155 GYEMIQEIGERTDNLWRPSPGSVYPTLQLLVDEGLISGTEAEGSKKLFEL
MAB_0383c|M.abscessus_ATCC_199 GYEMIREIAERSNNIWRPSPGSVYPTLQLLVDEGLITETEGGSSRKQFEL
Mb0048c|M.bovis_AF2122/97 VYQLTDKGRRRFGELVADTGPHNYTDDGFGVHLAFFNRTPAEARMRILEG
Rv0047c|M.tuberculosis_H37Rv VYQLTDKGRRRFGELVADTGPHNYTDDGFGVHLAFFNRTPAEARMRILEG
TH_1310|M.thermoresistible__bu VYRLTEAGKQRFTELVADTGPQNYSDDGFGVHLAFFNRTPAEARMRILEG
*.: * : : *. : . :: : . : :*
MMAR_5206|M.marinum_M TEQGREAADKIETPPWDEIAEGVD---PAHINLRTAMRQLIGAVMQTAHA
MUL_4279|M.ulcerans_Agy99 TEQGREAADKIETPPWDEIAEGVD---PAHINLRTAMRQLIGAVMQTAHA
MLBr_02313|M.leprae_Br4923 TDDGRAAAAKVEMPPWDQIAQGIN---PGYINLRTAMNQLFGAVTQSAHT
MAV_0407|M.avium_104 TDDGRAAAEKIETPPWDEIAEGAD---PGHMNLRAAIGQLFGAVGQSAHT
Mflv_1330|M.gilvum_PYR-GCK TDDGRAAAEKIDTAPWDAMAEQAD---PGAVNLRNAAGQLMGAVAQSAHA
Mvan_5462|M.vanbaalenii_PYR-1 TEDGRAAAEKIETAPWDEITEAFKDEAPEAMGLRTAVGQLMGAVAQSAHA
MSMEG_6227|M.smegmatis_MC2_155 TEAGRAAAEAIETPPWEQIAEDVD---PAAVNLRGAIAQLMGAVAQSAYT
MAB_0383c|M.abscessus_ATCC_199 TEEGTAAAEKLDTPPWEKINEDAD---PSVLDLRSALGQLMGAVAQSAHA
Mb0048c|M.bovis_AF2122/97 R---RRQVEERREGLREAVARASS-----------SFDRYTRQLHQLGLE
Rv0047c|M.tuberculosis_H37Rv R---RRQVEERREGLREAVARASS-----------SFDRYTRQLHQLGLE
TH_1310|M.thermoresistible__bu R---RRQVEERREGLREAIARASN-----------SFDRYTRQLHQLGLE
. : : . . : : : * .
MMAR_5206|M.marinum_M ASPEQQQRVIDIINNARREIYGILGEE-
MUL_4279|M.ulcerans_Agy99 ASPEQQQRVIDIINNARREIYGILGEE-
MLBr_02313|M.leprae_Br4923 ASADQQQRIIDTINNARREIYGILGEN-
MAV_0407|M.avium_104 ASPEQQQRIVDILNNARREIYGILGED-
Mflv_1330|M.gilvum_PYR-GCK ATPEQQQRILDIVNNARREIYSVLGED-
Mvan_5462|M.vanbaalenii_PYR-1 ATPEQQQRIVDIVNNARREIYQILGED-
MSMEG_6227|M.smegmatis_MC2_155 ATEDQQQRILDVVNNARREIYQILGEE-
MAB_0383c|M.abscessus_ATCC_199 ASPEQQQRIIEIVNSARKQIYGILGETD
Mb0048c|M.bovis_AF2122/97 SSEREVKWLNELIAAERAAPNPAEQT--
Rv0047c|M.tuberculosis_H37Rv SSEREVKWLNELIAAERAAPNPAEQT--
TH_1310|M.thermoresistible__bu SSEREVNWLNDLIAAERMAQGRAEQP--
:: : : : : : *