For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LHAEGPPSVICIRLLVGLVFLSEGIQKFMYPDQLGPGRFERIGIPAATFFADLDGVVEIVCGTLVLLGLL TRVAAVPLLIDMVGAIVLTKLRALQPGGFLGVEGFWGMAHAARTDLSMLLGLIFLLWSGPGRWSLDRRLS KRATACGAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3486 | - | - | 100% (149) | hypothetical protein Rv3486 |
| M. tuberculosis H37Rv | Rv3005c | - | 8e-06 | 26.87% (134) | hypothetical protein Rv3005c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3516 | - | 6e-83 | 100.00% (149) | hypothetical protein Mb3516 |
| M. gilvum PYR-GCK | Mflv_2914 | - | 7e-07 | 30.71% (140) | DoxX family protein |
| M. leprae Br4923 | MLBr_00956 | - | 8e-08 | 29.01% (131) | putative integral membrane protein |
| M. abscessus ATCC 19977 | MAB_4289 | - | 2e-05 | 31.16% (138) | hypothetical protein MAB_4289 |
| M. marinum M | MMAR_4330 | - | 1e-05 | 26.72% (131) | hypothetical protein MMAR_4330 |
| M. avium 104 | MAV_1260 | - | 8e-05 | 25.95% (131) | DoxX subfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_4292 | - | 6e-07 | 28.26% (138) | integral membrane protein |
| M. thermoresistible (build 8) | TH_0215 | - | 4e-09 | 26.62% (139) | integral membrane protein |
| M. ulcerans Agy99 | MUL_0140 | - | 8e-06 | 26.72% (131) | hypothetical protein MUL_0140 |
| M. vanbaalenii PYR-1 | Mvan_3593 | - | 5e-09 | 30.71% (140) | DoxX family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3486|M.tuberculosis_H37Rv --------------------------------------MHAEGPPSVICI
Mb3516|M.bovis_AF2122/97 --------------------------------------MHAEGPPSVICI
Mflv_2914|M.gilvum_PYR-GCK ------------------------------MTT-FDARLASYSSPMLSIF
Mvan_3593|M.vanbaalenii_PYR-1 ------------------------------MTTNLDARLTSYSAPVLSIF
MSMEG_4292|M.smegmatis_MC2_155 ------------------------------MTTNLDTRLATYSPVVVAIF
TH_0215|M.thermoresistible__bu LIGPDRSDRIDRTGAAIRRAARPIWLYRLLMTTTVDARLARLSTPALALF
MAB_4289|M.abscessus_ATCC_1997 --------------MRPRHGTCSQTNEGALINPQHAARLLGWMIPTG--A
MMAR_4330|M.marinum_M ---------------------------------------MAPYDVGLLIL
MUL_0140|M.ulcerans_Agy99 ---------------------------------------MAPYDVGLLIL
MAV_1260|M.avium_104 ---------------------------------------MTPYDVGLLIL
MLBr_00956|M.leprae_Br4923 ---------------------------------------MTSYDIGLLIL
Rv3486|M.tuberculosis_H37Rv RLLVGLVFLSEGIQKFMYPDQLGPGR---FERIGIPAATFFADLDGVVEI
Mb3516|M.bovis_AF2122/97 RLLVGLVFLSEGIQKFMYPDQLGPGR---FERIGIPAATFFADLDGVVEI
Mflv_2914|M.gilvum_PYR-GCK RIMFGVLFTLHGTMKLFGWP----------LGAAVPVGTWPYWFAGLIEV
Mvan_3593|M.vanbaalenii_PYR-1 RIVFGLLFTLHGAQKVLAWPTGMQAGPGDFTGPAVPVGTWPYWWAGLLEI
MSMEG_4292|M.smegmatis_MC2_155 RIVFGFLFAVHGASKLFAWPVDS-------GSGAVPVGTWPYWYAGVIEL
TH_0215|M.thermoresistible__bu RIIIGLLFALHGAMKLFGWP----------HGESVPVGTWPVWWAGLIEL
MAB_4289|M.abscessus_ATCC_1997 RLVFGVIFLLEGTQKVFGWWSGSPTG----SGHPEPFLNWPYWWAGVFEL
MMAR_4330|M.marinum_M RLVLGLTMAAHGFNKFFGGGRIPGTAR-WFESIGMKPGKFHATVAAITEV
MUL_0140|M.ulcerans_Agy99 RLVLGLTMAAHGFNKFFGGGRIPGTAR-WFESIGMKPGKFHATVAAITEV
MAV_1260|M.avium_104 RLVLGVTLAAHGYNKFFGGGRIPGTAR-WFESIGMKPGKFHATVAASTEM
MLBr_00956|M.leprae_Br4923 RLVLGLTLAAHGYNKFFCGGRIPGTAR-WFESIGMKPGTFHATVAATTEI
*::.*. : .* *.: .: . *:
Rv3486|M.tuberculosis_H37Rv VCGTLVLLGLLTRVAAVPLLIDMVGAIVLTKLRALQ--PGGFLGVEGFWG
Mb3516|M.bovis_AF2122/97 VCGTLVLLGLLTRVAAVPLLIDMVGAIVLTKLRALQ--PGGFLGVEGFWG
Mflv_2914|M.gilvum_PYR-GCK VCGILITVGFFTRIAAFIAAGHMAVAYFWQHWGIIGGEPKSFWPLGGDA-
Mvan_3593|M.vanbaalenii_PYR-1 VLGLLITVGLFTRIAAFIAAGQMAVAYFWQHL------PKAFFPIE----
MSMEG_4292|M.smegmatis_MC2_155 VLGLLIMVGLFTRIAAFIASGHMAVAYFWQHQ------PKGLLPLE----
TH_0215|M.thermoresistible__bu IVGLLVTVGLFTRISAIIGSGQMAVAYFWMHWPPLEGEPTSFWPVV----
MAB_4289|M.abscessus_ATCC_1997 VLGSLLTVGLRTRLAAVLAAGMMAYAYFFEHL------QVHWEPMQ----
MMAR_4330|M.marinum_M SAGLGLAAGLLTPIPAAGFVSLMFVAAWTVHR------PNGFFIVK----
MUL_0140|M.ulcerans_Agy99 SAGLGLAAGLLTPIPAAGFVSLMFVAAWTVHR------PNGFFIVK----
MAV_1260|M.avium_104 AAGLGLAAGLLTPIPAAGFVSLMLVAAWTVHR------PNGFFIVK----
MLBr_00956|M.leprae_Br4923 SAGLGLAAGLLTPIPAAGFVSLMMVAAWMVHR------PNGFFIVK----
* : *: * :.* * * : :
Rv3486|M.tuberculosis_H37Rv MAHAARTDLSMLLGLIFLLWSG-PGRWSLD-------------RRLSKRA
Mb3516|M.bovis_AF2122/97 MAHAARTDLSMLLGLIFLLWSG-PGRWSLD-------------RRLSKRA
Mflv_2914|M.gilvum_PYR-GCK GGNGGELAILYCFAFLLLATLG-AGAWSVDGRRQ----VAGGSGVRRGRV
Mvan_3593|M.vanbaalenii_PYR-1 --NGGEPAILFCFGFLLLVAMG-AGAWSID-------------ALRQGRA
MSMEG_4292|M.smegmatis_MC2_155 --NGGEPTVLFCFGFLLLFAIG-GGAFALD-------------AARAKR-
TH_0215|M.thermoresistible__bu --NGGEPALLYCFGFLLLAATG-PGAWALD-------------AMMRRRA
MAB_4289|M.abscessus_ATCC_1997 --NGGAFAATFCWGLLLLAVTANDTRLSLD-------------RVLARRA
MMAR_4330|M.marinum_M --EGWEYNLVLALSAVAVATIG-AGKLSLDWVIFGNNWLNGWPGLVASLG
MUL_0140|M.ulcerans_Agy99 --EGWEYNLVLALSAVAVATIG-AGKLSLDWVIFGNNWLNGWPGLVASLG
MAV_1260|M.avium_104 --EGWEYNLVLAASAVVVATLG-AGRLSLDWLVFGKNWMDGWNGLLISLL
MLBr_00956|M.leprae_Br4923 --EGWEYNLVLATGAVVVATLG-AGRFSLDWLIFGKNWFDSCDGLLISVL
.. . : : . ::*
Rv3486|M.tuberculosis_H37Rv TACGAR--------------------------
Mb3516|M.bovis_AF2122/97 TACGAR--------------------------
Mflv_2914|M.gilvum_PYR-GCK VTGTAAPPVTAAPAAQPVRRGGLLSRFRRNRY
Mvan_3593|M.vanbaalenii_PYR-1 VVRS----------------------------
MSMEG_4292|M.smegmatis_MC2_155 --------------------------------
TH_0215|M.thermoresistible__bu PATA----------------------------
MAB_4289|M.abscessus_ATCC_1997 --------------------------------
MMAR_4330|M.marinum_M LGLAGAFGQLLIFYRPPARQAG----------
MUL_0140|M.ulcerans_Agy99 LGLAGAFGQLLIFYRPPARRAG----------
MAV_1260|M.avium_104 LGLAGAIGQLVIFYRPPAKQTG----------
MLBr_00956|M.leprae_Br4923 LGFAGALGQLLIFYRPPVKKTS----------