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M. tuberculosis H37Rv Rv3421c (-)

annotation: hypothetical protein Rv3421c
coordinates: 3839059 - 3839694
length: 211

SRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAALTMADLDAVVVG
CGPGPFTGLRAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTDARRREVYWARYCDGIRTVGPA
VNAAADVDPGPALAVAGAPEHAALFALPCVEPSRPSPAGLVAAVNWADKPAPLVPLYLRRPDAKPLAVCT
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3421c--100% (211)hypothetical protein Rv3421c
M. tuberculosis H37RvRv3419cgcp2e-0731.50% (127) putative DNA-binding/iron metalloprotein/AP endonuclease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3455c-1e-119100.00% (211) hypothetical protein Mb3455c
M. gilvum PYR-GCKMflv_4931-2e-7673.13% (201) peptidase M22, glycoprotease
M. leprae Br4923MLBr_00378-1e-8375.61% (205) putative acetyltransferase
M. abscessus ATCC 19977MAB_3736c-1e-6359.61% (203) hypothetical protein MAB_3736c
M. marinum MMMAR_1122-3e-8980.00% (205) hypothetical protein MMAR_1122
M. avium 104MAV_4369-2e-8779.60% (201) peptidase M22, glycoprotease
M. smegmatis MC2 155MSMEG_1578-9e-7871.01% (207) peptidase M22, glycoprotease
M. thermoresistible (build 8)TH_1691-2e-7169.12% (204) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0882-2e-8980.00% (205) hypothetical protein MUL_0882
M. vanbaalenii PYR-1Mvan_1487-7e-7773.13% (201) peptidase M22, glycoprotease

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4931|M.gilvum_PYR-GCK          ----MSRLVLAVDTATPAVTAGIVRV-DGDAIEVLAEQVTVDARAHAEQL
Mvan_1487|M.vanbaalenii_PYR-1       ----MSRLVLAIDTATPAVTAGVLRV-DGDAVEVLAEQVTVDARAHAERL
MSMEG_1578|M.smegmatis_MC2_155      ----MTRTVLTIDTATPAVSAGVVRLSDGEAPATLAERVTIDARAHAEQL
Rv3421c|M.tuberculosis_H37Rv        MSRVQISTVLAIDTATPAVTAGIVRR-H--DLVVLGERVTVDARAHAERL
Mb3455c|M.bovis_AF2122/97           MSRVQISTVLAIDTATPAVTAGIVRR-H--DLVVLGERVTVDARAHAERL
MMAR_1122|M.marinum_M               -----MTIILALDTSTPAVTAGVVQL-TGSECVALAERVTVDARAHAERL
MUL_0882|M.ulcerans_Agy99           -----MTIILALDTSTPAVTAGVVQL-TGSECVALAERVTVDARAHAERL
MAV_4369|M.avium_104                ----MSPLVLALDTSTPAVTAGIVRR-D--DLSVLAQRITVDARAHAERL
MLBr_00378|M.leprae_Br4923          -----MSIVLAIDTATAAVTAGIVAF-DGHDCFTLAERVTVDAKAHVERL
TH_1691|M.thermoresistible__bu      ----MTMLILTIDTATPAVSAGVVRR-TPAGEELLAEKVTVDARAHAERL
MAB_3736c|M.abscessus_ATCC_199      -----MTLILALDTATAAITAGLVRRAPDGSVQPLAERITMGAKGHAEAL
                                            :*::**:*.*::**::          *.:::*:.*:.*.* *

Mflv_4931|M.gilvum_PYR-GCK          TPNIVAALGDAGIDASRLDAVVVGCGPGPFTGLRVGMATAAAFGHALGVP
Mvan_1487|M.vanbaalenii_PYR-1       TPNIVDALADAGVSVGQLDAVVVGCGPGPFTGLRVGMATAAAFGHALGVP
MSMEG_1578|M.smegmatis_MC2_155      TPNIVAALGDAGITAGDLDAVVVGCGPGPFTGLRVGMASAAAFAHAIGVP
Rv3421c|M.tuberculosis_H37Rv        TPNVLAALADAALTMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIP
Mb3455c|M.bovis_AF2122/97           TPNVLAALADAALTMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIP
MMAR_1122|M.marinum_M               TPNVLAALAGAALTMADLNAVVVGCGPGPFTGLRAGMATGAAYGHALDIP
MUL_0882|M.ulcerans_Agy99           TPNVLAALAGAALTMADLNAVVVGCGPGPFTGLRAGMATGAAYGHALDIP
MAV_4369|M.avium_104                TPNVLAALRDSGLNMTDLAAVVVGCGPGPFTGLRAGMATAAAYGHALGIP
MLBr_00378|M.leprae_Br4923          TPNVLVALADAELAMCELDAVVVGCGPGPFTGLRVGMATAAAYGHALGIP
TH_1691|M.thermoresistible__bu      TPNVVAALAEAGLAFDDLDAVVVGCGPGPFTGLRVGMASAAAYGHALDIP
MAB_3736c|M.abscessus_ATCC_199      TPNIGVACADAGVAVGDLGAIVVGCGPGPFTGLRVGMATAAAMGLALDIP
                                    ***:  *   : :    * *:*************.***:.** . *:.:*

Mflv_4931|M.gilvum_PYR-GCK          VHGVCSLDAIA---AGTTGDVLVVTDARRREVYWARYRDGRRVDGPAVNS
Mvan_1487|M.vanbaalenii_PYR-1       VRGVCSLDAIA---AGSTGDVLVVTDARRREVYWARYRDGLRVDGPAVNA
MSMEG_1578|M.smegmatis_MC2_155      VHGVCSLDAIG---GDTRGDVLVVTDARRREVYWARYHDGARVAGPSVNA
Rv3421c|M.tuberculosis_H37Rv        VYGVCSLDAIG---GQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNA
Mb3455c|M.bovis_AF2122/97           VYGVCSLDAIG---GQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNA
MMAR_1122|M.marinum_M               VYGVCSLDAIG---GLTTGDTLVVTDARRREVYWARYRDGVRTHGPAVNA
MUL_0882|M.ulcerans_Agy99           VYGVCSLDAIG---GLTTGDTLVVTDARRREVYWARYRDGVRTHGPAVNA
MAV_4369|M.avium_104                VHGVCSLDAIG---GQTTGDTLVVTGARRREVYWARYRDGVRTDGPAVAA
MLBr_00378|M.leprae_Br4923          VHGVCSLDAIG---VRTTGDTLVVTDARRHEVYWARYRDGVRIAGPAVGS
TH_1691|M.thermoresistible__bu      VHGVCSLDAIGVDTADTAGHVLVVTDARRREVYWARYRGGVRTDGPAVDS
MAB_3736c|M.abscessus_ATCC_199      VYPVCTLDAIG---HGTAGRVLVVTDARRREVYWAGYSDGVRVSGPAVDA
                                    *  **:****.     : * .****.***:***** * .* *  **:* :

Mflv_4931|M.gilvum_PYR-GCK          AVDVP----AGAAAVAGSPEHTALFELPRLAPVYPSAAGLVAAVRDWDTD
Mvan_1487|M.vanbaalenii_PYR-1       AVDVP----GGADAVAGSPEHAALFELPRLAPVYPTAAGLVAAVADWVSE
MSMEG_1578|M.smegmatis_MC2_155      PADVPALLDAPVAAVAGSPAHTALFDLPVLEQVYPTPAGLVAAVADWD-D
Rv3421c|M.tuberculosis_H37Rv        AADVDP---GPALAVAGAPEHAALFALPCVEPSRPSPAGLVAAVN-WADK
Mb3455c|M.bovis_AF2122/97           AADVDP---GPALAVAGAPEHAALFALPCVEPSRPSPAGLVAAVN-WADK
MMAR_1122|M.marinum_M               PGDVDP---GTAHAVAGSPEHAGLFDLPRCEPSYPTVAGLAAAVN-WAQD
MUL_0882|M.ulcerans_Agy99           PGDVDP---GTAHAVAGSPEHAGLFDLPRCEPSYPTVAGLAAAVN-WAQD
MAV_4369|M.avium_104                PADVDP---GGAEAVAGSPEHARLFGLPVTGPAHPTPAGLVAAVGDWSVR
MLBr_00378|M.leprae_Br4923          PTDVDP---GTALTVAGSPEHAALFGLPLCEPIYPTPAGLVAAVPDWSVS
TH_1691|M.thermoresistible__bu      PADVPT-----ADAVAGSRDHIGLFDLPALPPARPTPVGLVRVVPDWDSP
MAB_3736c|M.abscessus_ATCC_199      PADVSL---DGYTQVAGSPDHTTLFDLPAVDRHYPSPSRLVQVAG-WDEP
                                    . **          ***:  *  ** **      *:   *. ..  *   

Mflv_4931|M.gilvum_PYR-GCK          PAPLVPLYLRRPDAKPSQAVKR----------------------------
Mvan_1487|M.vanbaalenii_PYR-1       PDPLVPLYLRRPDAKPPRAVAR----------------------------
MSMEG_1578|M.smegmatis_MC2_155      PQPLVPLYLRRPDAKPSAAVKR----------------------------
Rv3421c|M.tuberculosis_H37Rv        PAPLVPLYLRRPDAKPLAVCT-----------------------------
Mb3455c|M.bovis_AF2122/97           PAPLVPLYLRRPDAKPLAVCT-----------------------------
MMAR_1122|M.marinum_M               PAPLVPLYLRRPDAKPLAARP-----------------------------
MUL_0882|M.ulcerans_Agy99           PAPLVPLYLRRPDAKPLAARP-----------------------------
MAV_4369|M.avium_104                PQPLVPLYLRRPDATPRAARP-----------------------------
MLBr_00378|M.leprae_Br4923          PIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNP
TH_1691|M.thermoresistible__bu      PAALKPLYLRRPDAKPAVARNR----------------------------
MAB_3736c|M.abscessus_ATCC_199      PGALTPLYLRRPDAKEPRR-------------------------------
                                    * .* .********.                                   

Mflv_4931|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1487|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1578|M.smegmatis_MC2_155      --------------------------------------------------
Rv3421c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3455c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1122|M.marinum_M               --------------------------------------------------
MUL_0882|M.ulcerans_Agy99           --------------------------------------------------
MAV_4369|M.avium_104                --------------------------------------------------
MLBr_00378|M.leprae_Br4923          WPAAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAV
TH_1691|M.thermoresistible__bu      --------------------------------------------------
MAB_3736c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4931|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1487|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1578|M.smegmatis_MC2_155      --------------------------------------------------
Rv3421c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3455c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1122|M.marinum_M               --------------------------------------------------
MUL_0882|M.ulcerans_Agy99           --------------------------------------------------
MAV_4369|M.avium_104                --------------------------------------------------
MLBr_00378|M.leprae_Br4923          DPAYRGRGVGRRLLGELLDFAGSGAIYLEVRTDNETAIALYRSVGFERIG
TH_1691|M.thermoresistible__bu      --------------------------------------------------
MAB_3736c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4931|M.gilvum_PYR-GCK          ---------------------
Mvan_1487|M.vanbaalenii_PYR-1       ---------------------
MSMEG_1578|M.smegmatis_MC2_155      ---------------------
Rv3421c|M.tuberculosis_H37Rv        ---------------------
Mb3455c|M.bovis_AF2122/97           ---------------------
MMAR_1122|M.marinum_M               ---------------------
MUL_0882|M.ulcerans_Agy99           ---------------------
MAV_4369|M.avium_104                ---------------------
MLBr_00378|M.leprae_Br4923          LRPRYYPASGADAYLMRREAQ
TH_1691|M.thermoresistible__bu      ---------------------
MAB_3736c|M.abscessus_ATCC_199      ---------------------