For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_1578 (-)

annotation: peptidase M22, glycoprotease
coordinates: 1668416 - 1669060
length: 214

VTRTVLTIDTATPAVSAGVVRLSDGEAPATLAERVTIDARAHAEQLTPNIVAALGDAGITAGDLDAVVVG
CGPGPFTGLRVGMASAAAFAHAIGVPVHGVCSLDAIGGDTRGDVLVVTDARRREVYWARYHDGARVAGPS
VNAPADVPALLDAPVAAVAGSPAHTALFDLPVLEQVYPTPAGLVAAVADWDDPQPLVPLYLRRPDAKPSA
AVKR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1578--100% (214)peptidase M22, glycoprotease
M. smegmatis MC2 155MSMEG_1580-3e-0832.80% (125) O-sialoglycoprotein endopeptidase
M. smegmatis MC2 155MSMEG_5923-6e-0528.30% (159) acetyl-CoA acetyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3455c-6e-7871.01% (207) hypothetical protein Mb3455c
M. gilvum PYR-GCKMflv_4931-6e-8977.67% (215) peptidase M22, glycoprotease
M. tuberculosis H37RvRv3421c-6e-7871.01% (207) hypothetical protein Rv3421c
M. leprae Br4923MLBr_00378-7e-7667.79% (208) putative acetyltransferase
M. abscessus ATCC 19977MAB_3736c-3e-6562.25% (204) hypothetical protein MAB_3736c
M. marinum MMMAR_1122-2e-7568.60% (207) hypothetical protein MMAR_1122
M. avium 104MAV_4369-3e-7668.27% (208) peptidase M22, glycoprotease
M. thermoresistible (build 8)TH_1691-3e-7566.97% (218) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0882-1e-7568.60% (207) hypothetical protein MUL_0882
M. vanbaalenii PYR-1Mvan_1487-8e-8473.49% (215) peptidase M22, glycoprotease

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4931|M.gilvum_PYR-GCK          ----MSRLVLAVDTATPAVTAGIVRV-DGDAIEVLAEQVTVDARAHAEQL
Mvan_1487|M.vanbaalenii_PYR-1       ----MSRLVLAIDTATPAVTAGVLRV-DGDAVEVLAEQVTVDARAHAERL
MSMEG_1578|M.smegmatis_MC2_155      ----MTRTVLTIDTATPAVSAGVVRLSDGEAPATLAERVTIDARAHAEQL
Mb3455c|M.bovis_AF2122/97           MSRVQISTVLAIDTATPAVTAGIVRR-H--DLVVLGERVTVDARAHAERL
Rv3421c|M.tuberculosis_H37Rv        MSRVQISTVLAIDTATPAVTAGIVRR-H--DLVVLGERVTVDARAHAERL
MMAR_1122|M.marinum_M               -----MTIILALDTSTPAVTAGVVQL-TGSECVALAERVTVDARAHAERL
MUL_0882|M.ulcerans_Agy99           -----MTIILALDTSTPAVTAGVVQL-TGSECVALAERVTVDARAHAERL
MAV_4369|M.avium_104                ----MSPLVLALDTSTPAVTAGIVRR-D--DLSVLAQRITVDARAHAERL
MLBr_00378|M.leprae_Br4923          -----MSIVLAIDTATAAVTAGIVAF-DGHDCFTLAERVTVDAKAHVERL
TH_1691|M.thermoresistible__bu      ----MTMLILTIDTATPAVSAGVVRR-TPAGEELLAEKVTVDARAHAERL
MAB_3736c|M.abscessus_ATCC_199      -----MTLILALDTATAAITAGLVRRAPDGSVQPLAERITMGAKGHAEAL
                                            :*::**:*.*::**::          *.:::*:.*:.*.* *

Mflv_4931|M.gilvum_PYR-GCK          TPNIVAALGDAGIDASRLDAVVVGCGPGPFTGLRVGMATAAAFGHALGVP
Mvan_1487|M.vanbaalenii_PYR-1       TPNIVDALADAGVSVGQLDAVVVGCGPGPFTGLRVGMATAAAFGHALGVP
MSMEG_1578|M.smegmatis_MC2_155      TPNIVAALGDAGITAGDLDAVVVGCGPGPFTGLRVGMASAAAFAHAIGVP
Mb3455c|M.bovis_AF2122/97           TPNVLAALADAALTMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIP
Rv3421c|M.tuberculosis_H37Rv        TPNVLAALADAALTMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIP
MMAR_1122|M.marinum_M               TPNVLAALAGAALTMADLNAVVVGCGPGPFTGLRAGMATGAAYGHALDIP
MUL_0882|M.ulcerans_Agy99           TPNVLAALAGAALTMADLNAVVVGCGPGPFTGLRAGMATGAAYGHALDIP
MAV_4369|M.avium_104                TPNVLAALRDSGLNMTDLAAVVVGCGPGPFTGLRAGMATAAAYGHALGIP
MLBr_00378|M.leprae_Br4923          TPNVLVALADAELAMCELDAVVVGCGPGPFTGLRVGMATAAAYGHALGIP
TH_1691|M.thermoresistible__bu      TPNVVAALAEAGLAFDDLDAVVVGCGPGPFTGLRVGMASAAAYGHALDIP
MAB_3736c|M.abscessus_ATCC_199      TPNIGVACADAGVAVGDLGAIVVGCGPGPFTGLRVGMATAAAMGLALDIP
                                    ***:  *   : :    * *:*************.***:.** . *:.:*

Mflv_4931|M.gilvum_PYR-GCK          VHGVCSLDAIA---AGTTGDVLVVTDARRREVYWARYRDGRRVDGPAVNS
Mvan_1487|M.vanbaalenii_PYR-1       VRGVCSLDAIA---AGSTGDVLVVTDARRREVYWARYRDGLRVDGPAVNA
MSMEG_1578|M.smegmatis_MC2_155      VHGVCSLDAIG---GDTRGDVLVVTDARRREVYWARYHDGARVAGPSVNA
Mb3455c|M.bovis_AF2122/97           VYGVCSLDAIG---GQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNA
Rv3421c|M.tuberculosis_H37Rv        VYGVCSLDAIG---GQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNA
MMAR_1122|M.marinum_M               VYGVCSLDAIG---GLTTGDTLVVTDARRREVYWARYRDGVRTHGPAVNA
MUL_0882|M.ulcerans_Agy99           VYGVCSLDAIG---GLTTGDTLVVTDARRREVYWARYRDGVRTHGPAVNA
MAV_4369|M.avium_104                VHGVCSLDAIG---GQTTGDTLVVTGARRREVYWARYRDGVRTDGPAVAA
MLBr_00378|M.leprae_Br4923          VHGVCSLDAIG---VRTTGDTLVVTDARRHEVYWARYRDGVRIAGPAVGS
TH_1691|M.thermoresistible__bu      VHGVCSLDAIGVDTADTAGHVLVVTDARRREVYWARYRGGVRTDGPAVDS
MAB_3736c|M.abscessus_ATCC_199      VYPVCTLDAIG---HGTAGRVLVVTDARRREVYWAGYSDGVRVSGPAVDA
                                    *  **:****.     : * .****.***:***** * .* *  **:* :

Mflv_4931|M.gilvum_PYR-GCK          AVDVP----AGAAAVAGSPEHTALFELPRLAPVYPSAAGLVAAVRDWDTD
Mvan_1487|M.vanbaalenii_PYR-1       AVDVP----GGADAVAGSPEHAALFELPRLAPVYPTAAGLVAAVADWVSE
MSMEG_1578|M.smegmatis_MC2_155      PADVPALLDAPVAAVAGSPAHTALFDLPVLEQVYPTPAGLVAAVADWD-D
Mb3455c|M.bovis_AF2122/97           AADVDP---GPALAVAGAPEHAALFALPCVEPSRPSPAGLVAAVN-WADK
Rv3421c|M.tuberculosis_H37Rv        AADVDP---GPALAVAGAPEHAALFALPCVEPSRPSPAGLVAAVN-WADK
MMAR_1122|M.marinum_M               PGDVDP---GTAHAVAGSPEHAGLFDLPRCEPSYPTVAGLAAAVN-WAQD
MUL_0882|M.ulcerans_Agy99           PGDVDP---GTAHAVAGSPEHAGLFDLPRCEPSYPTVAGLAAAVN-WAQD
MAV_4369|M.avium_104                PADVDP---GGAEAVAGSPEHARLFGLPVTGPAHPTPAGLVAAVGDWSVR
MLBr_00378|M.leprae_Br4923          PTDVDP---GTALTVAGSPEHAALFGLPLCEPIYPTPAGLVAAVPDWSVS
TH_1691|M.thermoresistible__bu      PADVPT-----ADAVAGSRDHIGLFDLPALPPARPTPVGLVRVVPDWDSP
MAB_3736c|M.abscessus_ATCC_199      PADVSL---DGYTQVAGSPDHTTLFDLPAVDRHYPSPSRLVQVAG-WDEP
                                    . **          ***:  *  ** **      *:   *. ..  *   

Mflv_4931|M.gilvum_PYR-GCK          PAPLVPLYLRRPDAKPSQAVKR----------------------------
Mvan_1487|M.vanbaalenii_PYR-1       PDPLVPLYLRRPDAKPPRAVAR----------------------------
MSMEG_1578|M.smegmatis_MC2_155      PQPLVPLYLRRPDAKPSAAVKR----------------------------
Mb3455c|M.bovis_AF2122/97           PAPLVPLYLRRPDAKPLAVCT-----------------------------
Rv3421c|M.tuberculosis_H37Rv        PAPLVPLYLRRPDAKPLAVCT-----------------------------
MMAR_1122|M.marinum_M               PAPLVPLYLRRPDAKPLAARP-----------------------------
MUL_0882|M.ulcerans_Agy99           PAPLVPLYLRRPDAKPLAARP-----------------------------
MAV_4369|M.avium_104                PQPLVPLYLRRPDATPRAARP-----------------------------
MLBr_00378|M.leprae_Br4923          PIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNP
TH_1691|M.thermoresistible__bu      PAALKPLYLRRPDAKPAVARNR----------------------------
MAB_3736c|M.abscessus_ATCC_199      PGALTPLYLRRPDAKEPRR-------------------------------
                                    * .* .********.                                   

Mflv_4931|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1487|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1578|M.smegmatis_MC2_155      --------------------------------------------------
Mb3455c|M.bovis_AF2122/97           --------------------------------------------------
Rv3421c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1122|M.marinum_M               --------------------------------------------------
MUL_0882|M.ulcerans_Agy99           --------------------------------------------------
MAV_4369|M.avium_104                --------------------------------------------------
MLBr_00378|M.leprae_Br4923          WPAAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAV
TH_1691|M.thermoresistible__bu      --------------------------------------------------
MAB_3736c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4931|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1487|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1578|M.smegmatis_MC2_155      --------------------------------------------------
Mb3455c|M.bovis_AF2122/97           --------------------------------------------------
Rv3421c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1122|M.marinum_M               --------------------------------------------------
MUL_0882|M.ulcerans_Agy99           --------------------------------------------------
MAV_4369|M.avium_104                --------------------------------------------------
MLBr_00378|M.leprae_Br4923          DPAYRGRGVGRRLLGELLDFAGSGAIYLEVRTDNETAIALYRSVGFERIG
TH_1691|M.thermoresistible__bu      --------------------------------------------------
MAB_3736c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4931|M.gilvum_PYR-GCK          ---------------------
Mvan_1487|M.vanbaalenii_PYR-1       ---------------------
MSMEG_1578|M.smegmatis_MC2_155      ---------------------
Mb3455c|M.bovis_AF2122/97           ---------------------
Rv3421c|M.tuberculosis_H37Rv        ---------------------
MMAR_1122|M.marinum_M               ---------------------
MUL_0882|M.ulcerans_Agy99           ---------------------
MAV_4369|M.avium_104                ---------------------
MLBr_00378|M.leprae_Br4923          LRPRYYPASGADAYLMRREAQ
TH_1691|M.thermoresistible__bu      ---------------------
MAB_3736c|M.abscessus_ATCC_199      ---------------------