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KIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQANWYTNFGPNE RRFARALRDYLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSFTFVGVAQAALWTGYRPWFIDI DANTWQPCVHSARAVIERFRDRIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGER LGGRGACEIFSFHATKPFAVGEGGALVSRDPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLR QLVGLDRRLASRRKVLECYRTGMADAGVRFQDNANVASLCFASACCTSADHKAAVLGSLRRHAIEARDYY NPPQHRHPYFVTNAELVESTDLAVTADICSRIVSLPVHDHMAPDDVARVVAAVQEAEVRGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3402c | - | - | 100% (412) | hypothetical protein Rv3402c |
| M. tuberculosis H37Rv | Rv1519 | - | 5e-14 | 77.55% (49) | hypothetical protein Rv1519 |
| M. tuberculosis H37Rv | Rv1504c | - | 3e-10 | 28.78% (205) | hypothetical protein Rv1504c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3436c | - | 0.0 | 99.71% (350) | hypothetical protein Mb3436c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2610 | - | 3e-14 | 25.14% (346) | putative aminotransferase |
| M. marinum M | MMAR_2320 | wecE | 4e-12 | 26.60% (391) | pyridoxal phosphate-dependent enzyme, WecE |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3402c|M.tuberculosis_H37Rv -MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPS-----
Mb3436c|M.bovis_AF2122/97 -MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPS-----
MMAR_2320|M.marinum_M ---------------------------------MVEHKIPFNRPY-----
MAB_2610|M.abscessus_ATCC_1997 MSIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRD
:** *.
Rv3402c|M.tuberculosis_H37Rv --------------FPGPAELAEDFVQIAQANWYTNF-------------
Mb3436c|M.bovis_AF2122/97 --------------FPGPAELAEDFVQIAQANWYTNF-------------
MMAR_2320|M.marinum_M --------------MTG--QELNYIAEAHSCGHLAGD-------------
MAB_2610|M.abscessus_ATCC_1997 LATHPGLRDVTDVLIPGSAPDTVDFLPLARLVNAAELPAIRAAIDSVLPS
:.* : :
Rv3402c|M.tuberculosis_H37Rv -----GPNERRFARALRDYLGPHLHVATLANGTLALLAALHVSFGAGTRD
Mb3436c|M.bovis_AF2122/97 -----GPNERRFARALRDYLGPHLHVATLANGTLALLAALHVSFGAGTRD
MMAR_2320|M.marinum_M -----GPFTYRCHAWLEQQTGCRKALLTPSCTAALEMMALLLEIEEGDE-
MAB_2610|M.abscessus_ATCC_1997 GKFTSGPHVDAFEDEIATYLGIDHVIGASSGTDAMTAVLLALGAGPGTE-
** : * : : : * : * .
Rv3402c|M.tuberculosis_H37Rv RYLLMPSFTFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERFRD
Mb3436c|M.bovis_AF2122/97 RYLLMPSFTFVGVAQAALWTGYRPWFIDIDANTWQPCVHSACAVIERFRD
MMAR_2320|M.marinum_M --VILPSFTFVSTANAFVLRGGVPVFVDIRPDTLN---VDETLIEAAITP
MAB_2610|M.abscessus_ATCC_1997 --VILPANSFAATENAVFLTGARPVLVDTRADDHL---LDPTEVEAAITS
:::*: :*... :* . * * ::* .: . : :
Rv3402c|M.tuberculosis_H37Rv RIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGERL
Mb3436c|M.bovis_AF2122/97 RIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGERL
MMAR_2320|M.marinum_M RTRAIVPVHYAGVAC-EMDTIMSIARRHKLAVVEDAAQGT-MAYYRGRAL
MAB_2610|M.abscessus_ATCC_1997 RTVAVLPVHLYGAFA-DIHALTEVTSRHGIPVVEDGCQGI-----GLDGL
* .:: .: *. :: . .:: . :.:* *.. * *
Rv3402c|M.tuberculosis_H37Rv GGRGACEIFSFHATKPF-AVGEGGALVSRDPRLVEHAYKFQNFGLVQTRE
Mb3436c|M.bovis_AF2122/97 GGRGACEIFSFHATKPF-AVGEGGALVSRDPRLVEHAYKFQNFGLVQTRE
MMAR_2320|M.marinum_M GSIGDLGALSFHETKNV-ISGEGGALLVNSEEYIYRAEILRDKGTNRSRF
MAB_2610|M.abscessus_ATCC_1997 GHHSDAAILSFNPYKNLGAVGKAGAVATRLPGLARRVTELLYHGFAAGQK
* . :**: * . *:.**: . :. : * :
Rv3402c|M.tuberculosis_H37Rv S---------IQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECYRT
Mb3436c|M.bovis_AF2122/97 S---------IQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECYRT
MMAR_2320|M.marinum_M LRKEVDKYTWQDKGSSYLSSELIAAFLWAQFEDAERITRSRLDLWNYYHA
MAB_2610|M.abscessus_ATCC_1997 N------VKAAGYGLNSRLDNLQAAVLRARLDWLGENNLARSILARRYVD
* . .:: **. :: . :* : . *
Rv3402c|M.tuberculosis_H37Rv GMADAGVR------FQDNANVASLCFASACCTSADHKAAVLGSLRRHAIE
Mb3436c|M.bovis_AF2122/97 GMADAGVR------FQDNANVASLCFASACCTSADHKAAVLGSLRRHAIE
MMAR_2320|M.marinum_M GFESLEQRGLLRRPIIPEGCSHNAHMYYVLLAPGTDRAGVLAALAKEDIN
MAB_2610|M.abscessus_ATCC_1997 GLADLAESGLLR---LPHWDTDHVWHLFTVEVTKHDRDKVTESLRAAGVA
*: . . . .. .: * :* :
Rv3402c|M.tuberculosis_H37Rv ARDYYNPPQHRHPYFVTNAELVESTDLAVTADICSRIVSLPVHDHMAPDD
Mb3436c|M.bovis_AF2122/97 ARDY----------------------------------------------
MMAR_2320|M.marinum_M AVFHYVPLHDSP---AGRRYGRTSGDLTVTNDSSSRLIRLPMWVGLQEAD
MAB_2610|M.abscessus_ATCC_1997 TDLYYPVLTHRHRVPLVADLFEG-VRLPRTEAAHARMFQLPLYPTLTLAE
: :
Rv3402c|M.tuberculosis_H37Rv VARVVAAVQEAEVRGE
Mb3436c|M.bovis_AF2122/97 ----------------
MMAR_2320|M.marinum_M QNRVVDALTRILTFGA
MAB_2610|M.abscessus_ATCC_1997 QDRVIGVLHDVLG---