For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv3374 (echA18.1)

annotation: PROBABLE ENOYL-CoA HYDRATASE (FRAGMENT) ECHA18.1 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
coordinates: 3788368 - 3788616
length: 82

LVQKVVAPQDLAAATAKLVGQVCRQSAVTMRAAKVVANMHGRALTGADTDALIRFGVEAYEGADLREGVA
AFSQGRPPKFDD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3374echA18.1-100% (82)PROBABLE ENOYL-CoA HYDRATASE (FRAGMENT) ECHA18.1 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3408echA188e-42100.00% (82) enoyl-CoA hydratase
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_3887echA10_14e-0532.93% (82) enoyl-CoA hydratase EchA10_1
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv3374|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3408|M.bovis_AF2122/97         MRRRAMTKMDEASNPCGGDIEAEMCQLMREQPPAEGVVDRVALQRHRNVA
MUL_3887|M.ulcerans_Agy99        ---------------------------MSLEADSAGPEGSVTSRRDGTLL
                                                                                   

Rv3374|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3408|M.bovis_AF2122/97         LITLSHPQAQNALNLASWRRLKRLLDDLAGESGLRAVVLRGAGDKAFAAG
MUL_3887|M.ulcerans_Agy99        RITLDRPSRRNSLTRNMIEMLLDTLGGAATDDSLRAILIRGAAADFCAGA
                                                                                   

Rv3374|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3408|M.bovis_AF2122/97         ADIKEFPNTR--MSAADAAEYNESLAVCLRALTTMPIPVIAAVRGLAVGG
MUL_3887|M.ulcerans_Agy99        DWVAASTGTQRHRTGDLLRRIPHAAHRVIELLHTIHLPVVCGVQGWAAGL
                                                                                   

Rv3374|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3408|M.bovis_AF2122/97         GCELATACDVCIATDDARFGIPLGKLGVTTGFTEADTVARLIGPAALKYL
MUL_3887|M.ulcerans_Agy99        GANLALAADFTVATSDATFWEPFVVRGFSPDSGSTWLLPRLVGLARARRM
                                                                                   

Rv3374|M.tuberculosis_H37Rv      ----------------MVQKVVAPQDLAAATAKLVGQVCRQSAVTMRAAK
Mb3408|M.bovis_AF2122/97         LFSGELIGIEEAARWGLVQKVVAPQDLAAATAKLVGQVCRQSAVTMRAAK
MUL_3887|M.ulcerans_Agy99        LLLGEQVTAPEAADWGLIHQVVDATDLDSAVDELLTRLARGPTVAIGLAK
                                                 ::::** . ** :*. :*: ::.* .:*::  **

Rv3374|M.tuberculosis_H37Rv      VVANMHGRALTGADTDALIRFGVEAYEGADLREGVAAFSQGRPPKFDD-
Mb3408|M.bovis_AF2122/97         VVANMHGRALTGADTDALIRFGVEAYEGADLREGVAAFSQGRPPKFDD-
MUL_3887|M.ulcerans_Agy99        QALNHGQHATLTESMTHELFNLELTCRTSDFKEGLTAFRQHRTPKFEGR
                                  . *   :*    .    :     : . :*::**::** * *.***:.