For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VPSPSTTGHHAACGTGGTGFSVGSMRSPIRVGSGEPVLLLHPFLMSQTVWEKVAQQLADTGRFEVFAPTM AGHNGGPASGTRFCPRRCWPTTSNASSTNWAGKPAISSATRWAAGSRSNSNDVAGHAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3337 | - | - | 100% (128) | hypothetical protein Rv3337 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3370 | - | 1e-45 | 100.00% (83) | hypothetical protein Mb3370 |
| M. gilvum PYR-GCK | Mflv_4874 | - | 4e-19 | 71.43% (56) | alpha/beta hydrolase fold |
| M. leprae Br4923 | MLBr_00685 | - | 6e-27 | 74.29% (70) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_3685 | - | 2e-17 | 72.55% (51) | hypothetical protein MAB_3685 |
| M. marinum M | MMAR_1187 | - | 3e-18 | 80.85% (47) | hypothetical protein MMAR_1187 |
| M. avium 104 | MAV_4312 | - | 2e-16 | 79.55% (44) | hydrolase, alpha/beta fold family protein, putative |
| M. smegmatis MC2 155 | MSMEG_1655 | - | 4e-18 | 71.43% (56) | hydrolase, alpha/beta fold family protein, putative |
| M. thermoresistible (build 8) | TH_1972 | - | 5e-19 | 71.70% (53) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1555 | - | 1e-16 | 61.90% (63) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1972|M.thermoresistible__bu ------------------------MSERAPIHLGSG----EPVLLLHPFM
Mvan_1555|M.vanbaalenii_PYR-1 ------------------------MNLREPIHLGSG----EPVLLLHPFM
MSMEG_1655|M.smegmatis_MC2_155 ------------------------MVERAPIHLGSRDGNTEPILLLHPFL
Mflv_4874|M.gilvum_PYR-GCK ------------------------MAPREPIHRGTG----EPIVLLHPFL
MAB_3685|M.abscessus_ATCC_1997 ---------------MLEAILSKPSNRRAPIEMGEG----EPVLLLHPFM
MMAR_1187|M.marinum_M ------------------------------------------MLLLHPFL
MAV_4312|M.avium_104 -------------------------------------------MLLHGFL
MLBr_00685|M.leprae_Br4923 MPACQHQRHRPVVACGTRGTTFRVGSMRQPIHLGSG----EPVLLLHPFM
Rv3337|M.tuberculosis_H37Rv --MPSPSTTGHHAACGTGGTGFSVGSMRSPIRVGSG----EPVLLLHPFL
Mb3370|M.bovis_AF2122/97 --MPSPSTTGHHAACGTGGTGFSVGSMRSPIRVGSG----EPVLLLHPFL
:*** *:
TH_1972|M.thermoresistible__bu MSQSVWKDVAPRIAG----------TGRYEVYAPTMPGHNGG---VKGR-
Mvan_1555|M.vanbaalenii_PYR-1 MSQNVWKDVAPQLAGVDVANPSAPATGRYEVLAPTMPGHNGG---VKGR-
MSMEG_1655|M.smegmatis_MC2_155 LSQSVWKYVAPQLAD----------TGRYEVFAPTMADHNGG---PRGP-
Mflv_4874|M.gilvum_PYR-GCK CSQNVWRTVADQLAD----------TERFEVFAPTMVGHHGG---PKSPT
MAB_3685|M.abscessus_ATCC_1997 LSQSVWETVAEQLAD----------AG-YEVFAPTYPGHNGGGPMPKLPP
MMAR_1187|M.marinum_M LSQAVWEQVAQRLAD----------TGRYEVFAPTMASHNGG---PRAG-
MAV_4312|M.avium_104 MSQTVWDPVAPRLAD----------TGRYEVFAPTMAGHNGG---PYAG-
MLBr_00685|M.leprae_Br4923 MSQTVWEIVAPQLAN----------TERYEVFAPTMAAHHGG---PSAS-
Rv3337|M.tuberculosis_H37Rv MSQTVWEKVAQQLAD----------TGRFEVFAPTMAGHNGG---PASG-
Mb3370|M.bovis_AF2122/97 MSQTVWEKVAQQLAD----------TGRFEVFAPTMAGHNGG---PASG-
** ** ** ::*. : :** *** *:**
TH_1972|M.thermoresistible__bu -FFLDTAELADDMERRLDELGWDTAHIVGNSLGGWVAFELERRGRARTLT
Mvan_1555|M.vanbaalenii_PYR-1 -FFLDTAELADDMERRMDALGWDTAHVVGNSLGGWVAFELERRGRVRSLT
MSMEG_1655|M.smegmatis_MC2_155 -FLLDVAHLADDIERRMDEVGWTTAHIVGNSLGGWVAFELERRGRARTLT
Mflv_4874|M.gilvum_PYR-GCK WLLH-TEVLVDDIEHRMDQLGWDTAHIVGNSLGGWVAFELERRGRARTLT
MAB_3685|M.abscessus_ATCC_1997 FSQRSVDVYLDQIEQIMDQKGWETAHLVGNSLGGWIALGLALRGRARSVT
MMAR_1187|M.marinum_M TWFLSSAVLADHVERQMDELGWDSAHIVGNSLGGWVAFELERRGRARSVT
MAV_4312|M.avium_104 TWLLSSSVLADHVERQLDRLGWDSAHLVGNSLGGWVAFELERRGRARSVT
MLBr_00685|M.leprae_Br4923 SWMMSVSTLADHVEQQLDELGWDTAHLVGNSLGGWVVFELERRGRARSVT
Rv3337|M.tuberculosis_H37Rv TRFCP--------------------------------------RRCWPTT
Mb3370|M.bovis_AF2122/97 TRFLSSAVLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVT
* . *
TH_1972|M.thermoresistible__bu GIAPAGGWHRWSPAKYEIVGKFVLGFPVWAVAKLLGRRAARLPIARQLAF
Mvan_1555|M.vanbaalenii_PYR-1 AIAPAGGWHRWSLPKYEIVFKFVMGFPVWLTAKALGPRAARLPGARAAAS
MSMEG_1655|M.smegmatis_MC2_155 GIAPAGGWTRFTPAKYEIVAKFVGGLPIVLATKLLGQRVHRLPFTRHISY
Mflv_4874|M.gilvum_PYR-GCK AIAPAGGWPHHSLSKYETVLKFIMGGPALIAARLLGPRILNVPGARRLAT
MAB_3685|M.abscessus_ATCC_1997 AIAPAGGWTKYSPLKAEIVVKFAAMLPWLAFSRLLGRRAAGLPFAKFATA
MMAR_1187|M.marinum_M GIAPAGGWTRWSPAKFEVIIKFVMGIPLLALAWLLGPRVMRLPFSRRLAT
MAV_4312|M.avium_104 GIGAAGGWTRWSPVKFEVIGKFIGGMPLLLLARLLGQRILQLPLSRRLAT
MLBr_00685|M.leprae_Br4923 GIAPAGGWTRWSLAKFEVIAKFVAGMPLVAVARGLGSRALSLPFSHRLAS
Rv3337|M.tuberculosis_H37Rv SNASS---TNW------------AGKPAIS--------------------
Mb3370|M.bovis_AF2122/97 GIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLAT
. ..: . *
TH_1972|M.thermoresistible__bu VAVSAYPDGISDDDLVQIIDDVTHCAAYYQLLVKALLLPGLMELAETSVP
Mvan_1555|M.vanbaalenii_PYR-1 VPVSATPDGISDADMLDIIDDVTHCAAYYQLLVKALLLPGLMELADTRIP
MSMEG_1655|M.smegmatis_MC2_155 VAVAATADSLTDDDRRDLIDDLAHCPAYHKLLLKSLTTAGLMELPNSCTP
Mflv_4874|M.gilvum_PYR-GCK LPVSGPADGPSQSDLAALVEDATHCSAYLQLLVKTLRMPGLLELASLGAP
MAB_3685|M.abscessus_ATCC_1997 RMLCGETEALSLPDFHSIFEDITHCPAYFASLTSILPAPGLENLDTISVP
MMAR_1187|M.marinum_M YAISASPDGVSDAELLGCIDDVAHCPAYLQLLVKALLLHGLRELAENAVP
MAV_4312|M.avium_104 LPLSATPSGVSERQLSGVVEDAAHCPAYFQLLVKSLLQPGLLELAQTAVP
MLBr_00685|M.leprae_Br4923 LPLTGSPAGLSEHQLRNIVEDAGHCPAYFLLLIKTLLQPGLRELADITVP
Rv3337|M.tuberculosis_H37Rv ---SATRWAAGSRSNS---NDVAGHAA-----------------------
Mb3370|M.bovis_AF2122/97 LPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVP
. . . :* .*
TH_1972|M.thermoresistible__bu THLVVCEKDRVLPNPRFVDHFHKNLREITRYTELDGVGHIPMFEAPQRVA
Mvan_1555|M.vanbaalenii_PYR-1 THMVICEKDRVLPHPRFVNHFRKHLPESTRFTALDGVGHIPMFEAPGRIA
MSMEG_1655|M.smegmatis_MC2_155 THLVICEKDRVLPHPRFTRHFTRHLPANAEVTHLDGVGHVPMFEAPGRVT
Mflv_4874|M.gilvum_PYR-GCK TQLVLCEKDRVFPTPRGNRYFLTHLPDEARVVRLDGVGHIPMLEAPGAIT
MAB_3685|M.abscessus_ATCC_1997 AQLVLCEKDEIVPPGRFGKLIGEGLPGNARRITLAGMGHVPMLEAPGQVT
MMAR_1187|M.marinum_M AHLVICGKDRIIPAPRYSRHFTTHLPDDHRVTVLDNVGHVPMFEAPARVT
MAV_4312|M.avium_104 VQLVLCEKDRVVPPSRFSRHFTDHLPPETRITRLDGVGHVPMFEAPERVT
MLBr_00685|M.leprae_Br4923 VLLVLCEKDRVLPPPKYSRHFTDHLPERTQVTKFDGMGHVPMFEAPEVIT
Rv3337|M.tuberculosis_H37Rv --------------------------------------------------
Mb3370|M.bovis_AF2122/97 SHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRIT
TH_1972|M.thermoresistible__bu DLIVDFLDDHTGKRRQASPGAVG
Mvan_1555|M.vanbaalenii_PYR-1 DLIRDFLDEQIDGQRTTG-----
MSMEG_1655|M.smegmatis_MC2_155 ELITEFVDRHTERGRAAG-----
Mflv_4874|M.gilvum_PYR-GCK ELIADFVDDHSTPSGKAIG----
MAB_3685|M.abscessus_ATCC_1997 EVITDLIDPLVSAKRSAASDAG-
MMAR_1187|M.marinum_M ALISGFIEECCPHLRSAEPPAS-
MAV_4312|M.avium_104 TVLTDFIDDCVARSQRQQPPAS-
MLBr_00685|M.leprae_Br4923 KLITNFINQCSKPAEAASPAS--
Rv3337|M.tuberculosis_H37Rv -----------------------
Mb3370|M.bovis_AF2122/97 ELITSFIEECCPHVRAS------