For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv3278c (-)

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 3660651 - 3661169
length: 172

SYPENVLAAGEQVVLHRHPHWNRLIWPVVVLVLLTGLAAFGSGFVNSTPWQQIAKNVIHAVIWGIWLVIV
GWLTLWPFLSWLTTHFVVTNRRVMFRHGVLTRSGIDIPLARINSVEFRDRIFERIFRTGTLIIESASQDP
LEFYNIPRLREVHALLYHEVFDTLGSDESPS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3278c--100% (172)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. tuberculosis H37RvRv1226c-4e-0525.00% (96) hypothetical protein Rv1226c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3306c-1e-10099.42% (172) transmembrane protein
M. gilvum PYR-GCKMflv_4749-3e-7068.60% (172) membrane-flanked domain-containing protein
M. leprae Br4923MLBr_00733-3e-8783.14% (172) hypothetical protein MLBr_00733
M. abscessus ATCC 19977MAB_3625c-2e-7171.51% (172) hypothetical protein MAB_3625c
M. marinum MMMAR_1258-8e-9288.95% (172) hypothetical protein MMAR_1258
M. avium 104MAV_4246-1e-8483.14% (172) hypothetical protein MAV_4246
M. smegmatis MC2 155MSMEG_1818-2e-7474.42% (172) membrane flanked domain-containing protein
M. thermoresistible (build 8)TH_0887-2e-7270.35% (172) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_2630-9e-9288.95% (172) hypothetical protein MUL_2630
M. vanbaalenii PYR-1Mvan_1707-1e-7068.02% (172) membrane-flanked domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1818|M.smegmatis_MC2_155      ---------MGYPDNVLAGDEQVVLHRHPHWKRLIGPVFILIVATALASF
TH_0887|M.thermoresistible__bu      ---------VGYPDNVLASDEQVVLHRHPHWKALVAPVLTLLVASAVAAF
Mflv_4749|M.gilvum_PYR-GCK          MLNPQYSAAVGYPENVLAKDEHVVLHRHPHWGRLVLPAVFLIIASAAAAF
Mvan_1707|M.vanbaalenii_PYR-1       ---------MGYPENVLATDEHVVLHRHPHWGRLTIPALILIIASAAAAF
MAB_3625c|M.abscessus_ATCC_199      ---------MGYPENVLADDEQVVLHRHPHWKRLIGPALVLILSTGIAAF
Rv3278c|M.tuberculosis_H37Rv        ---------MSYPENVLAAGEQVVLHRHPHWNRLIWPVVVLVLLTGLAAF
Mb3306c|M.bovis_AF2122/97           ---------MSYPENVLAAGEQVVLHRHPHWNRLIWPVVVLVLLTGLAAF
MMAR_1258|M.marinum_M               ---------MGYPDNAMAAGEQVVLHRHPHWTRLVWPVVVLILITGLAAL
MUL_2630|M.ulcerans_Agy99           ---------MGYPDNAMAAGEQVVLHRHPHWARLVWPVVVLILITGLAAL
MLBr_00733|M.leprae_Br4923          ---------MRYPGNTLVAGEQVVLHRHPHWKRLIWPAVVLILATGLVSF
MAV_4246|M.avium_104                ---------MGYPDNVLAAGEHVIVHRHPHWKRLIGPVLVLILGTGLAAF
                                             : ** *.:. .*:*::******  *  *.. *:: :. .::

MSMEG_1818|M.smegmatis_MC2_155      GAAYVNTLHWDPTATLVVSLVILAIWLVIVGWLTLWPFLTWLTTHFVITD
TH_0887|M.thermoresistible__bu      AAGWVNTTDWDGTAKNVLYIVIGAIWLVVIGWLTLWPFLNWLTTHFVITD
Mflv_4749|M.gilvum_PYR-GCK          IAGYVNTLNWEQAAKTIVFGVIAAIWLVLVGWLAVWPFLNWWTTHFVITD
Mvan_1707|M.vanbaalenii_PYR-1       LAGYVNTLNWEQNAKTIVFAVIAAVWLILVGWLSIWPFLNWWTTHFVITD
MAB_3625c|M.abscessus_ATCC_199      VAAMVDNTDWQSTAKNVVMIAIGVVWLVLVGWLSLWPFLNWLTTHFVITD
Rv3278c|M.tuberculosis_H37Rv        GSGFVNSTPWQQIAKNVIHAVIWGIWLVIVGWLTLWPFLSWLTTHFVVTN
Mb3306c|M.bovis_AF2122/97           GSGFVNSTPWQQIAKNVIHAVIWGIWLVIVGWLTLWPFLSWLTTHFVVTN
MMAR_1258|M.marinum_M               GSGFVNSTQWQQLAKNIIHGVIWGIWLVIVGWLTLWPFLSWLTTHFVVTN
MUL_2630|M.ulcerans_Agy99           GSGFVNSTQWQQLAKNIIHGVIWGIWLVIVGWLTLWPFLSWLTTHFVVTN
MLBr_00733|M.leprae_Br4923          GSGYVNSTHWAQVAKNVIYGVLWGVWLVIVGWLTLWPFLNWLTTHFVVTN
MAV_4246|M.avium_104                GSGYLDSTHFEQLAKNIIHGVIWGIWLVIVGWLTLWPFFGWLTTHFVVTN
                                     :. ::.  :   *. ::  .:  :**:::***::***: * *****:*:

MSMEG_1818|M.smegmatis_MC2_155      RRVMFRHGLLTRSGIDIPLARINSVEFRHGLSDRILRTGTLIIESASQDP
TH_0887|M.thermoresistible__bu      RRVMFRYGVLTRAGIDIPLARINSVEFRHNLMDRILRTGTLIIESAAQDP
Mflv_4749|M.gilvum_PYR-GCK          RRVMYRHGLITRSGIDIPLARINSVEFRHGLVDRIFRTGTLIIESAAQDP
Mvan_1707|M.vanbaalenii_PYR-1       RRVMYRHGLLTRSGIDIPLARINSVEFRHGLVDRMFRTGTLIIESASQDP
MAB_3625c|M.abscessus_ATCC_199      RRVMFRHGLLSRSGIDIPLARINSVEFRHGLVDRILRTGTLIIESASQDP
Rv3278c|M.tuberculosis_H37Rv        RRVMFRHGVLTRSGIDIPLARINSVEFRDRIFERIFRTGTLIIESASQDP
Mb3306c|M.bovis_AF2122/97           RRVMFRHGVLTRSGIDIPLARINSVEFRDRIFERIFRTGTLIIESASQDP
MMAR_1258|M.marinum_M               RRVMYRQGVLTRSGIDIPLARINSVEFRDRIFERMLRTGTLIIESASQDP
MUL_2630|M.ulcerans_Agy99           RRVMYRQGVLTRSGIDIPLARINSVEFRDRIFERMLRTGTLIIESASQDP
MLBr_00733|M.leprae_Br4923          RRVMFRQGTLTRSGVDIPLARINSVEFRDRLFERMFRTGTLIIESASQDP
MAV_4246|M.avium_104                RRVMFRHGVATRTGIDIPLARINSVEFRDRITERMLRTGTLIIESASQDP
                                    ****:* *  :*:*:*************. : :*::**********:***

MSMEG_1818|M.smegmatis_MC2_155      LEFYDIPRVEQVHALLYHEVFDTLGSDESPS-------------
TH_0887|M.thermoresistible__bu      LSFEDIPRVEQVHALLYHEVFDTLGSEESPS-------------
Mflv_4749|M.gilvum_PYR-GCK          LEFQDIPRVEYVHSLLYHEVFDTLGSEESPS-------------
Mvan_1707|M.vanbaalenii_PYR-1       LEFQDIPRVEHVHSLLYHEVFDTLGSEESPS-------------
MAB_3625c|M.abscessus_ATCC_199      LEFHEIPRVEYVHSLLYHEVFDTLGSEEGDSRSTGRGRERPPAT
Rv3278c|M.tuberculosis_H37Rv        LEFYNIPRLREVHALLYHEVFDTLGSDESPS-------------
Mb3306c|M.bovis_AF2122/97           LEFYNIPRLREVHALLYHKVFDTLGSDESPS-------------
MMAR_1258|M.marinum_M               LEFYNIPRLREVHALLYHEVFDTLGSEEAPS-------------
MUL_2630|M.ulcerans_Agy99           LEFYNIPRLREVHALLYHEVFDTLGSEEAPS-------------
MLBr_00733|M.leprae_Br4923          VEFYNIPRLRQMYALLYHEVFDTLGSEESPS-------------
MAV_4246|M.avium_104                LEFHDIPRLREVHALLYHEVFDTLGSEESPS-------------
                                    :.* :***:. :::****:*******:*. *