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M. tuberculosis H37Rv Rv3222c (-)

annotation: hypothetical protein Rv3222c
coordinates: 3598353 - 3598904
length: 183

SSPVSSRRLANLVKESLQGSVLGGVVSDAVLPAVSDDVKPGAGEDAYRVPVVVAAGSGAVVQVGGLEVGS
AAVAGEVADTVAELFVCRPTEPDVGDFVGLAGGAGDAGQAGQQFGLGVGVRGESFGARRRLALSTVGASG
ATAGLRKTHDGHHGCQARGALTQRRLYIGNPSEITDTRMVHQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3222c--100% (183)hypothetical protein Rv3222c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3249c-1e-100100.00% (183) hypothetical protein Mb3249c
M. gilvum PYR-GCKMflv_5091-7e-0833.85% (130) triple helix repeat-containing collagen
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4316-3e-0637.06% (143) PE-PGRS family protein
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             MSFVWVSPELVSAAAADVAGIGSAVGAANTAAAAATTELLAAGGDEVSAA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             IAELFGMYGRDYQRIAVEAAGFHARVAALLGAGADSYGWAESSGVLSLQG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        -------MV--------------------TFG------------------
MMAR_4316|M.marinum_M             LQRDVWGMVNAPTQMLLGRPLIGDGADGGTVGGVGQSGGAGGLLWGNGGA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        GGATPTPTSLG---------------------------------------
MMAR_4316|M.marinum_M             GGVSTNPGAVGGAGGSAGLIGAGGAGGRGGAGGGGGVGGSGGWLAGVGGA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        -----AAAVDLSGTSCGLICNG----------------QDGTGQNGGILF
MMAR_4316|M.marinum_M             GGAGGVGAIGGAGGSAGLFGGGGSGGAGGAGDVGVAGGAGGVGGRGGWVF
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        GNGGSG-----WNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGG
MMAR_4316|M.marinum_M             GDGGSGGVGGSGGVGVVGGVGGVGGGTGVFGGGGAGGAGGVGGGTGGSGG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        N-------------------------------AGAFA----LFGNGGNGG
MMAR_4316|M.marinum_M             NGGWLIGAGGIGGDGGAGFAGLPGGFAGGDGGAGGFGGGGGLFGEGGAGG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        NGGVG----------VVGATGAVGAPGVAGATGATGVTSGVVGGNGEDAV
MMAR_4316|M.marinum_M             AGGVGGAGTSGGDAVVPGGVGGVGGSGGAGGAGGSGGGAGWLGTAGDGGV
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        G---------------------YGATGAAGAAGAAGAAGAAG-----AVG
MMAR_4316|M.marinum_M             GGVGGGGGGGGVGASGVGHQLAGGAGGAGGAGGAAGAGGAAGQGRGGTVG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        SAGAAGEAGETG------------TWGNAGLPGKAGDAGGAG-AVGAAGA
MMAR_4316|M.marinum_M             AAGVGGTGGVGGDGGAGDSGAAASAPGGAGGTGWAGGAGGAGGAGGAAAA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        AGTVGTAGATG------------------GTGTGANGGAGGVGGVGGTG-
MMAR_4316|M.marinum_M             GGTAGVGGAGGDGGAGGVGAEGAAGAGVVGGGAGGDGGAGGAAGAGGSGG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        -----------------AAGAAGGAGGLGETGTTGGAGG-----------
MMAR_4316|M.marinum_M             GGIGGGKAGTGGDGGIGGAGGTGGGGGNGDTYSTGGAGGDGGAGGAAGSA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             GGAGAGSGGAAGSAGSGGSGGDGGAGGASGRELGSNLGYAGGVGGDGGQG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        ---------------------------------VGGQGTAG---------
MMAR_4316|M.marinum_M             GQGGAAVGGLAGAAGSGGNGGAGGAGGASAVALVGGAGGAGGAGGQGGTA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --GTGGVGGIGGAGSTGAVGGVGGKGIQGG-QGLQGGKGGDGGAGGKGGD
MMAR_4316|M.marinum_M             GDGPGGVGGHGGSGGSGGIGGTGGDGYQSGDVGGQGGEGGAGGAAGAGGE
Rv3222c|M.tuberculosis_H37Rv      ---------MSSPVSSRRLANLVKESLQGS---VLGGVVSDAVLPAVSDD
Mb3249c|M.bovis_AF2122/97         ---------MSSPVSSRRLANLVKESLQGS---VLGGVVSDAVLPAVSDD
                                            ... .:  :..   .. *..     **  . .   . ..:

Mflv_5091|M.gilvum_PYR-GCK        ADSMGSAGA-----TGGKGGNG--------------------------GN
MMAR_4316|M.marinum_M             AGAQGLAGAGGTGGTGGQGGTGGIGAQGSNGHGVGGRPGTAGAVGGAGGA
Rv3222c|M.tuberculosis_H37Rv      VKP---------------------------------------------GA
Mb3249c|M.bovis_AF2122/97         VKP---------------------------------------------GA
                                  . .                                             * 

Mflv_5091|M.gilvum_PYR-GCK        GGRGGLFGKGGNAGNGADGGTGGAGGAGG---------------------
MMAR_4316|M.marinum_M             GGQGGAAGLDGTAGDGGVGGTGGRGGAGGDGAGGVGHQLAGGAGGDGGAG
Rv3222c|M.tuberculosis_H37Rv      GEDAYRVPVVVAAGSGAVVQVGG---------------------------
Mb3249c|M.bovis_AF2122/97         GEDAYRVPVVVAAGSGAVVQVGG---------------------------
                                  *  .        **.*.   .**                           

Mflv_5091|M.gilvum_PYR-GCK        ---------------------TGGTGGAGGTG------------------
MMAR_4316|M.marinum_M             GAAGVGGAAGAGSGGVVGAAGTGGTGGAGGNGGAGDTGVAASTPGDPGGV
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             GFAGGAGGAGGAGGASGVGGVNGVGGAGGDGGTGGAGGAGAGGDRTDGGR
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        ----------------------------GTGGTGGIGGAGSTG-------
MMAR_4316|M.marinum_M             GGVGGAGGDAGAGGVTGAGGSGGGVGNAGVGGAGGVGGAGGAGGAADGPG
Rv3222c|M.tuberculosis_H37Rv      ---------------------------------LEVGSAAVAG-------
Mb3249c|M.bovis_AF2122/97         ---------------------------------LEVGSAAVAG-------
                                                                     :*.*. :*       

Mflv_5091|M.gilvum_PYR-GCK        ------GTGGTGGTGGTGGTGGTGGTGGTGGTGGTG-------------G
MMAR_4316|M.marinum_M             LFGYDGGAGGAGGIGGAAGVGGSNGAGGTGGAGGVGGVGADSGLASRPGG
Rv3222c|M.tuberculosis_H37Rv      ---------EVADTVAELFVCRPTEP------------------------
Mb3249c|M.bovis_AF2122/97         ---------EVADTVAELFVCRPTEP------------------------
                                            ...  .   .  .  .                        

Mflv_5091|M.gilvum_PYR-GCK        KGGTGGTGGAGG----------TGGDGGTGGTGGTGGTGG----------
MMAR_4316|M.marinum_M             AGGAGGTGGAGGGAGSGAGGLGAGGDGGTGGAGGAGGVGSSAGWGSGLAG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        -TGGTGGTGGAGDGTGGTGGTGGTGGQGGQGGQGGTGG------------
MMAR_4316|M.marinum_M             QVGGAGGVGGAGGDSGGLGGTNGDGGAGGLGGRGGAGGSSTTVAGAGGGG
Rv3222c|M.tuberculosis_H37Rv      ---------DVGDFVGLAGGAGDAGQAGQQFGLG----------------
Mb3249c|M.bovis_AF2122/97         ---------DVGDFVGLAGGAGDAGQAGQQFGLG----------------
                                           ..*.  *  **:.. *  *   * *                

Mflv_5091|M.gilvum_PYR-GCK        ----------------------------------------TGGQGGLGGG
MMAR_4316|M.marinum_M             GRGGDGGSAGGGVGGGGVGGAAGSGGAGGAGGRGIDSYAAAGGRGGDGGA
Rv3222c|M.tuberculosis_H37Rv      -------------------------------------------VGVRGES
Mb3249c|M.bovis_AF2122/97         -------------------------------------------VGVRGES
                                                                              *  * .

Mflv_5091|M.gilvum_PYR-GCK        GGTGGQGGTGGTGGQGGTGGTGGTGGTGG--------TGGAGGDGGLGGL
MMAR_4316|M.marinum_M             GGIGGGGGLSGIGGAGGQGGSGGAAGTGGDVGGSPGEVGGAGGGGGFGGA
Rv3222c|M.tuberculosis_H37Rv      FGARRRLALSTVGASGATAGLRKTH-------------------------
Mb3249c|M.bovis_AF2122/97         FGARRRLALSTVGASGATAGLRKTH-------------------------
                                   *     . .  *. *. .*   :                          

Mflv_5091|M.gilvum_PYR-GCK        G-------GFGGSGGTGGQGGLGGPGGSTGGAGGAGGQAGTAGKG-----
MMAR_4316|M.marinum_M             GGAGGVGGGAGGSGGVGGSGGNGGLGVATGGAGGVGGQGGAAGAGGAAGA
Rv3222c|M.tuberculosis_H37Rv      ----------DGHHGCQARGALTQRRLYIGNPSEITDTRMVHQ-------
Mb3249c|M.bovis_AF2122/97         ----------DGHHGCQARGALTQRRLYIGNPSEITDTRMVHQ-------
                                            .*  *  . *.        *...   .   .         

Mflv_5091|M.gilvum_PYR-GCK        ----------GLFGGSGSAGKAGATGAAGASGGKGAQGATGAQGATGAQG
MMAR_4316|M.marinum_M             GATAAGAGGVGGLGGDGGNGGNGVRGAAGVAGGDGAVGGGGGAGGAGGQG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        ATGATG--------------------------------AAGKAGATGAAG
MMAR_4316|M.marinum_M             GAGVTGGSAGAGGQGGNGGLGGPGGDGGSAVRYQRVGGAGGVGGVGGAAG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        AAGAAGSAG--TTGAQGSAGT-----------------------------
MMAR_4316|M.marinum_M             AGGAAGQGGGGAVGAAGVGGTGGVGGNGGAGDAGVAGADGGGAGGSGWAG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             GAGGAGGQGGAANGGVAGDGGVGGNGGVGGVGGRGGDGANGAPGGGIDGT
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             GRPGGAGGQGGSGGRAGFGGAAGAGEGGEYGAAGVGGNGGDGGAGGRGGY
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             GTTGSGGLFGGSGGHGGVGGIGGNGGSAAAGGVNGNGGNGGIGGNAGDAG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        NGAN---------GANGSQGAAGKAG--------ATGTTGATGAAGEDGD
MMAR_4316|M.marinum_M             NGANGSLLHHAGDGGNGGRGGAGGAGGFAGDGEGSGGTAGSGGNGGKGGN
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        AGSGGSGINGG------------------------AGGAGGAGGEGGEG-
MMAR_4316|M.marinum_M             AGAGGNGVPAAGAAAGNGGLGGSGGAGGSGAIGAAAGGAGGAGGNGGTGG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        ----------------GDGGKGGAG----------AEGGAGGGGGAGGSG
MMAR_4316|M.marinum_M             NAGIGVMRGASTPALAGDGGVGGAGGLGGVARSVGGVGGVGGDGGSGGTG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        ---------------AGGAGGAGGSGGSG-----------GSGGSGGSGG
MMAR_4316|M.marinum_M             GIGTTGNSATNGYGGAGGAGGAGGVGGNGGFAALGTGGAAGSGGGGGTGG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        AAGDSDD-------------------------------------------
MMAR_4316|M.marinum_M             AGGVSDSPTTSRSVGGAGGVGGVGGNGGIGGNGQIGGDGGSGGAAGAGGA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             GAQNLTRSIQSANFGGAGGAGGVGGFGGVGGTGASGLGGSGGIGGDGGAG
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        --------------------------------------------------
MMAR_4316|M.marinum_M             GVGGDCSVPLSPGNGGDGGAGGDGGDGGDGGNGQPGGPGGAGGGAASGGA
Rv3222c|M.tuberculosis_H37Rv      --------------------------------------------------
Mb3249c|M.bovis_AF2122/97         --------------------------------------------------
                                                                                    

Mflv_5091|M.gilvum_PYR-GCK        ------------------------
MMAR_4316|M.marinum_M             GGYGQLGNGAAGADGNNGTPGADG
Rv3222c|M.tuberculosis_H37Rv      ------------------------
Mb3249c|M.bovis_AF2122/97         ------------------------