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PVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPHLWDDQTRAQRVTSELSHTQGE LRRVEELRRRLDDLPVLYELAAEEAGAAAADAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIR SGAGGVDAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAYGTLSVEQGTHRLVR ISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVT CQNEKSQLQNKIAAMRVLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTEYEVG NPAAVLDGDLDGFLEAGIRWRNRRNDD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3105c | prfB | - | 100% (378) | peptide chain release factor 2 |
| M. tuberculosis H37Rv | Rv1299 | prfA | 4e-50 | 37.54% (349) | peptide chain release factor 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3132c | prfB | 0.0 | 100.00% (378) | peptide chain release factor 2 |
| M. gilvum PYR-GCK | Mflv_4451 | prfB | 0.0 | 88.41% (371) | peptide chain release factor 2 |
| M. leprae Br4923 | MLBr_00667 | prfB | 0.0 | 90.32% (372) | peptide chain release factor 2 |
| M. abscessus ATCC 19977 | MAB_3478c | prfB | 0.0 | 87.03% (370) | peptide chain release factor 2 |
| M. marinum M | MMAR_1527 | prfB | 0.0 | 94.34% (371) | peptide chain release factor 2 PrfB |
| M. avium 104 | MAV_4006 | prfB | 0.0 | 93.53% (371) | peptide chain release factor 2 |
| M. smegmatis MC2 155 | MSMEG_2086 | prfB | 0.0 | 89.22% (371) | peptide chain release factor 2 |
| M. thermoresistible (build 8) | TH_2152 | prfB | 0.0 | 88.89% (369) | PROBABLE PEPTIDE CHAIN RELEASE FACTOR 2 PRFB (RF-2) |
| M. ulcerans Agy99 | MUL_2412 | prfB | 0.0 | 94.07% (371) | peptide chain release factor 2 |
| M. vanbaalenii PYR-1 | Mvan_1911 | prfB | 0.0 | 88.95% (371) | peptide chain release factor 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3105c|M.tuberculosis_H37Rv MPVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPH
Mb3132c|M.bovis_AF2122/97 MPVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPH
MMAR_1527|M.marinum_M -------MEPDRQAEIAALDSALTTVERVLDVEGLRSRIEKLEHEASDPK
MUL_2412|M.ulcerans_Agy99 -------MEPDRQAEIAALDSALTTVERVLDVEGLRSRIEKLEHEASDPK
MLBr_00667|M.leprae_Br4923 -------MEPDRQTDIAALDSTLTTVERVLDVEGLRTRIEKLEHEASDPK
MAV_4006|M.avium_104 -------MEPDRQADIAALDSTLTTVERVLDVDGLRARIEKLEHEASDPQ
TH_2152|M.thermoresistible__bu -------VDPDRQAEIAALDATLTTVERVLDVEGLRNRIQKLEQEASDPE
Mflv_4451|M.gilvum_PYR-GCK -------MDPDRQSDIAALDTTLTTVERVVNVDGLRGRIQQLESDASDPK
Mvan_1911|M.vanbaalenii_PYR-1 -------MDPDRQADIAALDATLTTVERVIDVDGLRGRIEQLEKDASDPQ
MSMEG_2086|M.smegmatis_MC2_155 -------MDPDRQADIAALDTTLTTVERVLDVDGLRNRIEQLEKDASDPN
MAB_3478c|M.abscessus_ATCC_199 -------MDLDCQADIADLDTTLTTVERVLDVDGLRARIKTLEEAAADPN
:: * *::** ** :*******::*:*** **: ** *:**.
Rv3105c|M.tuberculosis_H37Rv LWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAA
Mb3132c|M.bovis_AF2122/97 LWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAA
MMAR_1527|M.marinum_M LWDDQTRAQRVTSELSHTQGELRRVEELRRRLEDLPVLYELAAEEEGAAA
MUL_2412|M.ulcerans_Agy99 LWDDQTRAQRVTSELSHTQGELRRVEELRRRLEDLPVLYELAAEEEGAAA
MLBr_00667|M.leprae_Br4923 LWDDQVRAQRVTSELSHAQGELRRIEELRRRLDDLPVLYELAAEERAAAA
MAV_4006|M.avium_104 LWDDQARAQRVTSELSHAQGELRRIEELRARLDDLPVLYELAAEEGEGAA
TH_2152|M.thermoresistible__bu LWNDQANAQRVTSELSHAQGELRRVEELRRRVDDLPVLYELAAEEAGEDG
Mflv_4451|M.gilvum_PYR-GCK LWDDQARAQKVTSDLSHAQNELRRVEELRSRLDDLPVLYELAAEEEGAGS
Mvan_1911|M.vanbaalenii_PYR-1 LWDDQARAQKVTSDLSHAQGELRRIEELRGRLEDLPVLYELAAEE---GG
MSMEG_2086|M.smegmatis_MC2_155 LWDDQTRAQKVTSDLSHAQNELRRVEGLRQRLDDLPVLYELAAEA---GG
MAB_3478c|M.abscessus_ATCC_199 LWDDQARGQQVTSQLSHAQGELRRVEELRSRLDDLPVLYELAEES---ED
**:**...*:***:***:*.****:* ** *::********* *
Rv3105c|M.tuberculosis_H37Rv A---DAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
Mb3132c|M.bovis_AF2122/97 A---DAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MMAR_1527|M.marinum_M G---EALAEADAEFKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MUL_2412|M.ulcerans_Agy99 G---EALTEADAEFKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MLBr_00667|M.leprae_Br4923 ASGMEAFAEADAELKALRVDIEATEVRTLLSGEYDEREALITIRSGAGGV
MAV_4006|M.avium_104 ----EALAEADAELKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
TH_2152|M.thermoresistible__bu D----SLAEADEELEALKAEIEALEVRTLLSGEYDEREALVTIRAGAGGV
Mflv_4451|M.gilvum_PYR-GCK S---EAFAEADAELAKLREDIAGMEVRTLLSGEYDEREALVNIRSGAGGV
Mvan_1911|M.vanbaalenii_PYR-1 S---DEVAEADAELTKLREDIEAMEVRTLLSGEYDEREALVTIRSGAGGV
MSMEG_2086|M.smegmatis_MC2_155 P---DEVAEADAELAKLREDIEAMEVRTLLSGEYDEREAVVTIRSGAGGV
MAB_3478c|M.abscessus_ATCC_199 N---SVVAEADAERVKLREDIEAMEVRTLLSGEYDEREAVVTIRSGAGGV
.:*** * *: :* . ***************::.**:*****
Rv3105c|M.tuberculosis_H37Rv DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
Mb3132c|M.bovis_AF2122/97 DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MMAR_1527|M.marinum_M DAADWAEMLMRMYVRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MUL_2412|M.ulcerans_Agy99 DAADWAEMLMRMYVRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MLBr_00667|M.leprae_Br4923 DAADWAEMLMRMYIRWAEQHKYGVEVLDTSYAEEAGVKSATFAVHAPFAY
MAV_4006|M.avium_104 DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
TH_2152|M.thermoresistible__bu DAADWAEMLMRMYIRWAEKHGYPVEVYDISYAEEAGIKSATFAVKAPFAY
Mflv_4451|M.gilvum_PYR-GCK DAADWAEMLMRMYIRWAEQHDYPVEVFDTSYAEEAGIKSATFAVHAPYAY
Mvan_1911|M.vanbaalenii_PYR-1 DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPYAY
MSMEG_2086|M.smegmatis_MC2_155 DAADWAEMLMRMYIRWAEKHDYPVEIFDTSYAEEAGIKSATFAVHAPFAY
MAB_3478c|M.abscessus_ATCC_199 DAADWAEMLMRMYIRWAEAHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
*************:**** * * **: * *******:*******:**:**
Rv3105c|M.tuberculosis_H37Rv GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
Mb3132c|M.bovis_AF2122/97 GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MMAR_1527|M.marinum_M GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MUL_2412|M.ulcerans_Agy99 GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MLBr_00667|M.leprae_Br4923 GTLASEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVEITDHIDIPEGDV
MAV_4006|M.avium_104 GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
TH_2152|M.thermoresistible__bu GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPESDV
Mflv_4451|M.gilvum_PYR-GCK GNLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIDIPEGDV
Mvan_1911|M.vanbaalenii_PYR-1 GNLSVEQGTHRLVRISPFDNQNRRQTSFADVEVLPVTETTDHIEIPEGDV
MSMEG_2086|M.smegmatis_MC2_155 GTLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIEIPENDI
MAB_3478c|M.abscessus_ATCC_199 GTLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIDIPEGDL
*.*: ****************.*******:******.* ****:***.*:
Rv3105c|M.tuberculosis_H37Rv RVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMR
Mb3132c|M.bovis_AF2122/97 RVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMR
MMAR_1527|M.marinum_M RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
MUL_2412|M.ulcerans_Agy99 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
MLBr_00667|M.leprae_Br4923 RVDVYRSSGPGGQSVNTTDSAVRLTHVPTGLVVTCQNEKSQLQNKVSAMR
MAV_4006|M.avium_104 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKISAMR
TH_2152|M.thermoresistible__bu RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKLSAMR
Mflv_4451|M.gilvum_PYR-GCK RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
Mvan_1911|M.vanbaalenii_PYR-1 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
MSMEG_2086|M.smegmatis_MC2_155 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
MAB_3478c|M.abscessus_ATCC_199 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
**************************:*:*:**************::***
Rv3105c|M.tuberculosis_H37Rv VLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTE
Mb3132c|M.bovis_AF2122/97 VLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTE
MMAR_1527|M.marinum_M VLQAKLLERKRIEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MUL_2412|M.ulcerans_Agy99 VLQAKLLERKRIEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MLBr_00667|M.leprae_Br4923 VLQAKLLERKRLEERAELDALKGRGGSSWGNQIRSYVLHPYQMVKDLRNE
MAV_4006|M.avium_104 VLQAKLLERKRSEERAELDALKGEGGSSWGNQMRSYVLHPYQMVKDLRTE
TH_2152|M.thermoresistible__bu VLQAKLLELKRQEQRAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
Mflv_4451|M.gilvum_PYR-GCK VLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
Mvan_1911|M.vanbaalenii_PYR-1 VLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MSMEG_2086|M.smegmatis_MC2_155 VLQAKLLERKRLEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MAB_3478c|M.abscessus_ATCC_199 VLQARLLERKRQEERAEMDALKGDGGSSWGTQMRSYVLQPYQMVKDLRTE
****:*** ** *:***:****. ******.*:*****:*********.*
Rv3105c|M.tuberculosis_H37Rv YEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD-----
Mb3132c|M.bovis_AF2122/97 YEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD-----
MMAR_1527|M.marinum_M YEVGNPATVLDGDIDGFLEAGIRWRNRKDDD-----
MUL_2412|M.ulcerans_Agy99 YEVGNPATVLDGDIDGFLEAGIRWRNRKDDD-----
MLBr_00667|M.leprae_Br4923 YEVGNPTAVLDGDIDGFLEAGIRWRNRRDIS-----
MAV_4006|M.avium_104 YEVGNPAAVLDGDIDGFLEAGIRWRNRKDDE-----
TH_2152|M.thermoresistible__bu YEVGNPSAVLDGEIDGFLEAGIRWRNRRDAEVTAEK
Mflv_4451|M.gilvum_PYR-GCK YEVGNPAAVLDGDIDGFLEAGIRWRNQKVDDE----
Mvan_1911|M.vanbaalenii_PYR-1 YEVGNPSAVLDGDIDGFLEAGIRWRNRKDDE-----
MSMEG_2086|M.smegmatis_MC2_155 YEVGNPASVLDGDIDGFLEAGIRWRNRKDDD-----
MAB_3478c|M.abscessus_ATCC_199 YEVGNPAAVLDGDIDGFIEAGIRWRNRRDD------
******::****::***:********::