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VDPDRQADIAALDATLTTVERVIDVDGLRGRIEQLEKDASDPQLWDDQARAQKVTSDLSHAQGELRRIEE LRGRLEDLPVLYELAAEEGGSDEVAEADAELTKLREDIEAMEVRTLLSGEYDEREALVTIRSGAGGVDAA DWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPYAYGNLSVEQGTHRLVRISPFDNQNR RQTSFADVEVLPVTETTDHIEIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQ NKVSAMRVLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTEYEVGNPSAVLDGD IDGFLEAGIRWRNRKDDE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1911 | prfB | - | 100% (368) | peptide chain release factor 2 |
| M. vanbaalenii PYR-1 | Mvan_4339 | prfA | 6e-52 | 37.03% (343) | peptide chain release factor 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3132c | prfB | 0.0 | 88.95% (371) | peptide chain release factor 2 |
| M. gilvum PYR-GCK | Mflv_4451 | prfB | 0.0 | 91.91% (371) | peptide chain release factor 2 |
| M. tuberculosis H37Rv | Rv3105c | prfB | 0.0 | 88.95% (371) | peptide chain release factor 2 |
| M. leprae Br4923 | MLBr_00667 | prfB | 0.0 | 86.29% (372) | peptide chain release factor 2 |
| M. abscessus ATCC 19977 | MAB_3478c | prfB | 0.0 | 88.28% (367) | peptide chain release factor 2 |
| M. marinum M | MMAR_1527 | prfB | 0.0 | 88.41% (371) | peptide chain release factor 2 PrfB |
| M. avium 104 | MAV_4006 | prfB | 0.0 | 91.08% (370) | peptide chain release factor 2 |
| M. smegmatis MC2 155 | MSMEG_2086 | prfB | 0.0 | 92.66% (368) | peptide chain release factor 2 |
| M. thermoresistible (build 8) | TH_2152 | prfB | 0.0 | 86.22% (370) | PROBABLE PEPTIDE CHAIN RELEASE FACTOR 2 PRFB (RF-2) |
| M. ulcerans Agy99 | MUL_2412 | prfB | 0.0 | 88.14% (371) | peptide chain release factor 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1527|M.marinum_M -------MEPDRQAEIAALDSALTTVERVLDVEGLRSRIEKLEHEASDPK
MUL_2412|M.ulcerans_Agy99 -------MEPDRQAEIAALDSALTTVERVLDVEGLRSRIEKLEHEASDPK
Mb3132c|M.bovis_AF2122/97 MPVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPH
Rv3105c|M.tuberculosis_H37Rv MPVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPH
MLBr_00667|M.leprae_Br4923 -------MEPDRQTDIAALDSTLTTVERVLDVEGLRTRIEKLEHEASDPK
MAV_4006|M.avium_104 -------MEPDRQADIAALDSTLTTVERVLDVDGLRARIEKLEHEASDPQ
TH_2152|M.thermoresistible__bu -------VDPDRQAEIAALDATLTTVERVLDVEGLRNRIQKLEQEASDPE
Mvan_1911|M.vanbaalenii_PYR-1 -------MDPDRQADIAALDATLTTVERVIDVDGLRGRIEQLEKDASDPQ
Mflv_4451|M.gilvum_PYR-GCK -------MDPDRQSDIAALDTTLTTVERVVNVDGLRGRIQQLESDASDPK
MSMEG_2086|M.smegmatis_MC2_155 -------MDPDRQADIAALDTTLTTVERVLDVDGLRNRIEQLEKDASDPN
MAB_3478c|M.abscessus_ATCC_199 -------MDLDCQADIADLDTTLTTVERVLDVDGLRARIKTLEEAAADPN
:: * *::** ** :*******::*:*** **: ** *:**.
MMAR_1527|M.marinum_M LWDDQTRAQRVTSELSHTQGELRRVEELRRRLEDLPVLYELAAEEEGAAA
MUL_2412|M.ulcerans_Agy99 LWDDQTRAQRVTSELSHTQGELRRVEELRRRLEDLPVLYELAAEEEGAAA
Mb3132c|M.bovis_AF2122/97 LWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAA
Rv3105c|M.tuberculosis_H37Rv LWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAA
MLBr_00667|M.leprae_Br4923 LWDDQVRAQRVTSELSHAQGELRRIEELRRRLDDLPVLYELAAEERAAAA
MAV_4006|M.avium_104 LWDDQARAQRVTSELSHAQGELRRIEELRARLDDLPVLYELAAEEGEGAA
TH_2152|M.thermoresistible__bu LWNDQANAQRVTSELSHAQGELRRVEELRRRVDDLPVLYELAAEEAGEDG
Mvan_1911|M.vanbaalenii_PYR-1 LWDDQARAQKVTSDLSHAQGELRRIEELRGRLEDLPVLYELAAEE---GG
Mflv_4451|M.gilvum_PYR-GCK LWDDQARAQKVTSDLSHAQNELRRVEELRSRLDDLPVLYELAAEEEGAGS
MSMEG_2086|M.smegmatis_MC2_155 LWDDQTRAQKVTSDLSHAQNELRRVEGLRQRLDDLPVLYELAAEA---GG
MAB_3478c|M.abscessus_ATCC_199 LWDDQARGQQVTSQLSHAQGELRRVEELRSRLDDLPVLYELAEES---ED
**:**...*:***:***:*.****:* ** *::********* *
MMAR_1527|M.marinum_M G---EALAEADAEFKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MUL_2412|M.ulcerans_Agy99 G---EALTEADAEFKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
Mb3132c|M.bovis_AF2122/97 A---DAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
Rv3105c|M.tuberculosis_H37Rv A---DAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MLBr_00667|M.leprae_Br4923 ASGMEAFAEADAELKALRVDIEATEVRTLLSGEYDEREALITIRSGAGGV
MAV_4006|M.avium_104 ----EALAEADAELKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
TH_2152|M.thermoresistible__bu D----SLAEADEELEALKAEIEALEVRTLLSGEYDEREALVTIRAGAGGV
Mvan_1911|M.vanbaalenii_PYR-1 S---DEVAEADAELTKLREDIEAMEVRTLLSGEYDEREALVTIRSGAGGV
Mflv_4451|M.gilvum_PYR-GCK S---EAFAEADAELAKLREDIAGMEVRTLLSGEYDEREALVNIRSGAGGV
MSMEG_2086|M.smegmatis_MC2_155 P---DEVAEADAELAKLREDIEAMEVRTLLSGEYDEREAVVTIRSGAGGV
MAB_3478c|M.abscessus_ATCC_199 N---SVVAEADAERVKLREDIEAMEVRTLLSGEYDEREAVVTIRSGAGGV
.:*** * *: :* . ***************::.**:*****
MMAR_1527|M.marinum_M DAADWAEMLMRMYVRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MUL_2412|M.ulcerans_Agy99 DAADWAEMLMRMYVRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
Mb3132c|M.bovis_AF2122/97 DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
Rv3105c|M.tuberculosis_H37Rv DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MLBr_00667|M.leprae_Br4923 DAADWAEMLMRMYIRWAEQHKYGVEVLDTSYAEEAGVKSATFAVHAPFAY
MAV_4006|M.avium_104 DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
TH_2152|M.thermoresistible__bu DAADWAEMLMRMYIRWAEKHGYPVEVYDISYAEEAGIKSATFAVKAPFAY
Mvan_1911|M.vanbaalenii_PYR-1 DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPYAY
Mflv_4451|M.gilvum_PYR-GCK DAADWAEMLMRMYIRWAEQHDYPVEVFDTSYAEEAGIKSATFAVHAPYAY
MSMEG_2086|M.smegmatis_MC2_155 DAADWAEMLMRMYIRWAEKHDYPVEIFDTSYAEEAGIKSATFAVHAPFAY
MAB_3478c|M.abscessus_ATCC_199 DAADWAEMLMRMYIRWAEAHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
*************:**** * * **: * *******:*******:**:**
MMAR_1527|M.marinum_M GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MUL_2412|M.ulcerans_Agy99 GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
Mb3132c|M.bovis_AF2122/97 GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
Rv3105c|M.tuberculosis_H37Rv GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MLBr_00667|M.leprae_Br4923 GTLASEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVEITDHIDIPEGDV
MAV_4006|M.avium_104 GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
TH_2152|M.thermoresistible__bu GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPESDV
Mvan_1911|M.vanbaalenii_PYR-1 GNLSVEQGTHRLVRISPFDNQNRRQTSFADVEVLPVTETTDHIEIPEGDV
Mflv_4451|M.gilvum_PYR-GCK GNLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIDIPEGDV
MSMEG_2086|M.smegmatis_MC2_155 GTLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIEIPENDI
MAB_3478c|M.abscessus_ATCC_199 GTLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIDIPEGDL
*.*: ****************.*******:******.* ****:***.*:
MMAR_1527|M.marinum_M RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
MUL_2412|M.ulcerans_Agy99 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
Mb3132c|M.bovis_AF2122/97 RVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMR
Rv3105c|M.tuberculosis_H37Rv RVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMR
MLBr_00667|M.leprae_Br4923 RVDVYRSSGPGGQSVNTTDSAVRLTHVPTGLVVTCQNEKSQLQNKVSAMR
MAV_4006|M.avium_104 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKISAMR
TH_2152|M.thermoresistible__bu RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKLSAMR
Mvan_1911|M.vanbaalenii_PYR-1 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
Mflv_4451|M.gilvum_PYR-GCK RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
MSMEG_2086|M.smegmatis_MC2_155 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
MAB_3478c|M.abscessus_ATCC_199 RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
**************************:*:*:**************::***
MMAR_1527|M.marinum_M VLQAKLLERKRIEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MUL_2412|M.ulcerans_Agy99 VLQAKLLERKRIEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
Mb3132c|M.bovis_AF2122/97 VLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTE
Rv3105c|M.tuberculosis_H37Rv VLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTE
MLBr_00667|M.leprae_Br4923 VLQAKLLERKRLEERAELDALKGRGGSSWGNQIRSYVLHPYQMVKDLRNE
MAV_4006|M.avium_104 VLQAKLLERKRSEERAELDALKGEGGSSWGNQMRSYVLHPYQMVKDLRTE
TH_2152|M.thermoresistible__bu VLQAKLLELKRQEQRAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
Mvan_1911|M.vanbaalenii_PYR-1 VLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
Mflv_4451|M.gilvum_PYR-GCK VLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MSMEG_2086|M.smegmatis_MC2_155 VLQAKLLERKRLEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MAB_3478c|M.abscessus_ATCC_199 VLQARLLERKRQEERAEMDALKGDGGSSWGTQMRSYVLQPYQMVKDLRTE
****:*** ** *:***:****. ******.*:*****:*********.*
MMAR_1527|M.marinum_M YEVGNPATVLDGDIDGFLEAGIRWRNRKDDD-----
MUL_2412|M.ulcerans_Agy99 YEVGNPATVLDGDIDGFLEAGIRWRNRKDDD-----
Mb3132c|M.bovis_AF2122/97 YEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD-----
Rv3105c|M.tuberculosis_H37Rv YEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD-----
MLBr_00667|M.leprae_Br4923 YEVGNPTAVLDGDIDGFLEAGIRWRNRRDIS-----
MAV_4006|M.avium_104 YEVGNPAAVLDGDIDGFLEAGIRWRNRKDDE-----
TH_2152|M.thermoresistible__bu YEVGNPSAVLDGEIDGFLEAGIRWRNRRDAEVTAEK
Mvan_1911|M.vanbaalenii_PYR-1 YEVGNPSAVLDGDIDGFLEAGIRWRNRKDDE-----
Mflv_4451|M.gilvum_PYR-GCK YEVGNPAAVLDGDIDGFLEAGIRWRNQKVDDE----
MSMEG_2086|M.smegmatis_MC2_155 YEVGNPASVLDGDIDGFLEAGIRWRNRKDDD-----
MAB_3478c|M.abscessus_ATCC_199 YEVGNPAAVLDGDIDGFIEAGIRWRNRRDD------
******::****::***:********::