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M. bovis AF2122 / 97 Mb3132c (prfB)

annotation: peptide chain release factor 2
coordinates: 3429315 - 3430451
length: 378

MPVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPHLWDDQTRAQRVTSELSHTQG
ELRRVEELRRRLDDLPVLYELAAEEAGAAAADAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTI
RSGAGGVDAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAYGTLSVEQGTHRLV
RISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVV
TCQNEKSQLQNKIAAMRVLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTEYEV
GNPAAVLDGDLDGFLEAGIRWRNRRNDD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3132cprfB-100% (378)peptide chain release factor 2
M. bovis AF2122 / 97Mb1331prfA4e-5037.54% (349) peptide chain release factor 1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4451prfB0.088.41% (371) peptide chain release factor 2
M. tuberculosis H37RvRv3105cprfB0.0100.00% (378) peptide chain release factor 2
M. leprae Br4923MLBr_00667prfB0.090.32% (372) peptide chain release factor 2
M. abscessus ATCC 19977MAB_3478cprfB0.087.03% (370) peptide chain release factor 2
M. marinum MMMAR_1527prfB0.094.34% (371) peptide chain release factor 2 PrfB
M. avium 104MAV_4006prfB0.093.53% (371) peptide chain release factor 2
M. smegmatis MC2 155MSMEG_2086prfB0.089.22% (371) peptide chain release factor 2
M. thermoresistible (build 8)TH_2152prfB0.088.89% (369) PROBABLE PEPTIDE CHAIN RELEASE FACTOR 2 PRFB (RF-2)
M. ulcerans Agy99MUL_2412prfB0.094.07% (371) peptide chain release factor 2
M. vanbaalenii PYR-1Mvan_1911prfB0.088.95% (371) peptide chain release factor 2

CLUSTAL 2.0.9 multiple sequence alignment


Mb3132c|M.bovis_AF2122/97           MPVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPH
Rv3105c|M.tuberculosis_H37Rv        MPVTLAAVDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPH
MMAR_1527|M.marinum_M               -------MEPDRQAEIAALDSALTTVERVLDVEGLRSRIEKLEHEASDPK
MUL_2412|M.ulcerans_Agy99           -------MEPDRQAEIAALDSALTTVERVLDVEGLRSRIEKLEHEASDPK
MLBr_00667|M.leprae_Br4923          -------MEPDRQTDIAALDSTLTTVERVLDVEGLRTRIEKLEHEASDPK
MAV_4006|M.avium_104                -------MEPDRQADIAALDSTLTTVERVLDVDGLRARIEKLEHEASDPQ
TH_2152|M.thermoresistible__bu      -------VDPDRQAEIAALDATLTTVERVLDVEGLRNRIQKLEQEASDPE
Mflv_4451|M.gilvum_PYR-GCK          -------MDPDRQSDIAALDTTLTTVERVVNVDGLRGRIQQLESDASDPK
Mvan_1911|M.vanbaalenii_PYR-1       -------MDPDRQADIAALDATLTTVERVIDVDGLRGRIEQLEKDASDPQ
MSMEG_2086|M.smegmatis_MC2_155      -------MDPDRQADIAALDTTLTTVERVLDVDGLRNRIEQLEKDASDPN
MAB_3478c|M.abscessus_ATCC_199      -------MDLDCQADIADLDTTLTTVERVLDVDGLRARIKTLEEAAADPN
                                           :: * *::** ** :*******::*:*** **: **  *:**.

Mb3132c|M.bovis_AF2122/97           LWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAA
Rv3105c|M.tuberculosis_H37Rv        LWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAA
MMAR_1527|M.marinum_M               LWDDQTRAQRVTSELSHTQGELRRVEELRRRLEDLPVLYELAAEEEGAAA
MUL_2412|M.ulcerans_Agy99           LWDDQTRAQRVTSELSHTQGELRRVEELRRRLEDLPVLYELAAEEEGAAA
MLBr_00667|M.leprae_Br4923          LWDDQVRAQRVTSELSHAQGELRRIEELRRRLDDLPVLYELAAEERAAAA
MAV_4006|M.avium_104                LWDDQARAQRVTSELSHAQGELRRIEELRARLDDLPVLYELAAEEGEGAA
TH_2152|M.thermoresistible__bu      LWNDQANAQRVTSELSHAQGELRRVEELRRRVDDLPVLYELAAEEAGEDG
Mflv_4451|M.gilvum_PYR-GCK          LWDDQARAQKVTSDLSHAQNELRRVEELRSRLDDLPVLYELAAEEEGAGS
Mvan_1911|M.vanbaalenii_PYR-1       LWDDQARAQKVTSDLSHAQGELRRIEELRGRLEDLPVLYELAAEE---GG
MSMEG_2086|M.smegmatis_MC2_155      LWDDQTRAQKVTSDLSHAQNELRRVEGLRQRLDDLPVLYELAAEA---GG
MAB_3478c|M.abscessus_ATCC_199      LWDDQARGQQVTSQLSHAQGELRRVEELRSRLDDLPVLYELAEES---ED
                                    **:**...*:***:***:*.****:* ** *::********* *      

Mb3132c|M.bovis_AF2122/97           A---DAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
Rv3105c|M.tuberculosis_H37Rv        A---DAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MMAR_1527|M.marinum_M               G---EALAEADAEFKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MUL_2412|M.ulcerans_Agy99           G---EALTEADAEFKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
MLBr_00667|M.leprae_Br4923          ASGMEAFAEADAELKALRVDIEATEVRTLLSGEYDEREALITIRSGAGGV
MAV_4006|M.avium_104                ----EALAEADAELKALRADIEATEVRTLLSGEYDEREALVTIRSGAGGV
TH_2152|M.thermoresistible__bu      D----SLAEADEELEALKAEIEALEVRTLLSGEYDEREALVTIRAGAGGV
Mflv_4451|M.gilvum_PYR-GCK          S---EAFAEADAELAKLREDIAGMEVRTLLSGEYDEREALVNIRSGAGGV
Mvan_1911|M.vanbaalenii_PYR-1       S---DEVAEADAELTKLREDIEAMEVRTLLSGEYDEREALVTIRSGAGGV
MSMEG_2086|M.smegmatis_MC2_155      P---DEVAEADAELAKLREDIEAMEVRTLLSGEYDEREAVVTIRSGAGGV
MAB_3478c|M.abscessus_ATCC_199      N---SVVAEADAERVKLREDIEAMEVRTLLSGEYDEREAVVTIRSGAGGV
                                          .:*** *   *: :* . ***************::.**:*****

Mb3132c|M.bovis_AF2122/97           DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
Rv3105c|M.tuberculosis_H37Rv        DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MMAR_1527|M.marinum_M               DAADWAEMLMRMYVRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MUL_2412|M.ulcerans_Agy99           DAADWAEMLMRMYVRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
MLBr_00667|M.leprae_Br4923          DAADWAEMLMRMYIRWAEQHKYGVEVLDTSYAEEAGVKSATFAVHAPFAY
MAV_4006|M.avium_104                DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
TH_2152|M.thermoresistible__bu      DAADWAEMLMRMYIRWAEKHGYPVEVYDISYAEEAGIKSATFAVKAPFAY
Mflv_4451|M.gilvum_PYR-GCK          DAADWAEMLMRMYIRWAEQHDYPVEVFDTSYAEEAGIKSATFAVHAPYAY
Mvan_1911|M.vanbaalenii_PYR-1       DAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPYAY
MSMEG_2086|M.smegmatis_MC2_155      DAADWAEMLMRMYIRWAEKHDYPVEIFDTSYAEEAGIKSATFAVHAPFAY
MAB_3478c|M.abscessus_ATCC_199      DAADWAEMLMRMYIRWAEAHKYPVEVFDTSYAEEAGIKSATFAVHAPFAY
                                    *************:**** * * **: * *******:*******:**:**

Mb3132c|M.bovis_AF2122/97           GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
Rv3105c|M.tuberculosis_H37Rv        GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MMAR_1527|M.marinum_M               GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MUL_2412|M.ulcerans_Agy99           GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
MLBr_00667|M.leprae_Br4923          GTLASEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVEITDHIDIPEGDV
MAV_4006|M.avium_104                GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDV
TH_2152|M.thermoresistible__bu      GTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPESDV
Mflv_4451|M.gilvum_PYR-GCK          GNLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIDIPEGDV
Mvan_1911|M.vanbaalenii_PYR-1       GNLSVEQGTHRLVRISPFDNQNRRQTSFADVEVLPVTETTDHIEIPEGDV
MSMEG_2086|M.smegmatis_MC2_155      GTLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIEIPENDI
MAB_3478c|M.abscessus_ATCC_199      GTLSVEQGTHRLVRISPFDNQSRRQTSFADVEVLPVVETTDHIDIPEGDL
                                    *.*: ****************.*******:******.* ****:***.*:

Mb3132c|M.bovis_AF2122/97           RVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMR
Rv3105c|M.tuberculosis_H37Rv        RVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMR
MMAR_1527|M.marinum_M               RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
MUL_2412|M.ulcerans_Agy99           RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
MLBr_00667|M.leprae_Br4923          RVDVYRSSGPGGQSVNTTDSAVRLTHVPTGLVVTCQNEKSQLQNKVSAMR
MAV_4006|M.avium_104                RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKISAMR
TH_2152|M.thermoresistible__bu      RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKLSAMR
Mflv_4451|M.gilvum_PYR-GCK          RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
Mvan_1911|M.vanbaalenii_PYR-1       RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
MSMEG_2086|M.smegmatis_MC2_155      RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMR
MAB_3478c|M.abscessus_ATCC_199      RVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMR
                                    **************************:*:*:**************::***

Mb3132c|M.bovis_AF2122/97           VLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTE
Rv3105c|M.tuberculosis_H37Rv        VLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTE
MMAR_1527|M.marinum_M               VLQAKLLERKRIEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MUL_2412|M.ulcerans_Agy99           VLQAKLLERKRIEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MLBr_00667|M.leprae_Br4923          VLQAKLLERKRLEERAELDALKGRGGSSWGNQIRSYVLHPYQMVKDLRNE
MAV_4006|M.avium_104                VLQAKLLERKRSEERAELDALKGEGGSSWGNQMRSYVLHPYQMVKDLRTE
TH_2152|M.thermoresistible__bu      VLQAKLLELKRQEQRAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
Mflv_4451|M.gilvum_PYR-GCK          VLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
Mvan_1911|M.vanbaalenii_PYR-1       VLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MSMEG_2086|M.smegmatis_MC2_155      VLQAKLLERKRLEERAELDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTE
MAB_3478c|M.abscessus_ATCC_199      VLQARLLERKRQEERAEMDALKGDGGSSWGTQMRSYVLQPYQMVKDLRTE
                                    ****:*** ** *:***:****. ******.*:*****:*********.*

Mb3132c|M.bovis_AF2122/97           YEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD-----
Rv3105c|M.tuberculosis_H37Rv        YEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD-----
MMAR_1527|M.marinum_M               YEVGNPATVLDGDIDGFLEAGIRWRNRKDDD-----
MUL_2412|M.ulcerans_Agy99           YEVGNPATVLDGDIDGFLEAGIRWRNRKDDD-----
MLBr_00667|M.leprae_Br4923          YEVGNPTAVLDGDIDGFLEAGIRWRNRRDIS-----
MAV_4006|M.avium_104                YEVGNPAAVLDGDIDGFLEAGIRWRNRKDDE-----
TH_2152|M.thermoresistible__bu      YEVGNPSAVLDGEIDGFLEAGIRWRNRRDAEVTAEK
Mflv_4451|M.gilvum_PYR-GCK          YEVGNPAAVLDGDIDGFLEAGIRWRNQKVDDE----
Mvan_1911|M.vanbaalenii_PYR-1       YEVGNPSAVLDGDIDGFLEAGIRWRNRKDDE-----
MSMEG_2086|M.smegmatis_MC2_155      YEVGNPASVLDGDIDGFLEAGIRWRNRKDDD-----
MAB_3478c|M.abscessus_ATCC_199      YEVGNPAAVLDGDIDGFIEAGIRWRNRRDD------
                                    ******::****::***:********::