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MPIPFADGMLSRLGRRGAALDLIEEFEDESGEPPASLSPADLLAAEPALLLQKMENRLVRHHLANPDVLS GEQLRKLRYILNFARLADFEPGAAGPGGSRGRGDISVGGQVAPWRSRVVDALYAPLREEPDPVTALEGAK DVLATLVDDQDDQRRVLIERHGSDFSATELDAEVGYKKLVTVLGGGGGAGFVYIGGMQRLLAAGQVPDYM IGSSFGSIIGSLVARELPVPIDEYAEWAKTVSYRAILGPERRRSRHGLAGMFTLRFDQFAHTLLSRADGE RMRMSDLAIPFDVVVAGVRRQPYAALPSRFRHRERSTLTLRSLPFLPIGIGPWVAARMWQVAAFIDLRVV KPIVISADGATRDVNVVDAASFSSAIPGVLHHETSDPRMLPILDELCADQDVAAMVDGGAASNVPVELAW ERVRDGRLGTRNACYLAFDCFHPHWDPRHLWLVPITQAVQLQMVRNLPYADHLVRFEPTLSPVNLAPSAA AIDRACRWGRDSVEPAIAVTSALLEPTWWEGDRPPAAEPKERTKSAASSMSAVMAAIQAPTGRFRRWRSR HLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3091 | - | - | 100% (563) | hypothetical protein Rv3091 |
| M. tuberculosis H37Rv | Rv1063c | - | 3e-06 | 35.71% (70) | hypothetical protein Rv1063c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3118 | - | 0.0 | 100.00% (563) | hypothetical protein Mb3118 |
| M. gilvum PYR-GCK | Mflv_2030 | - | 4e-05 | 32.86% (70) | patatin |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4751 | - | 1e-06 | 37.14% (70) | hypothetical protein MAB_4751 |
| M. marinum M | MMAR_1571 | - | 0.0 | 78.69% (563) | hypothetical protein MMAR_1571 |
| M. avium 104 | MAV_1190 | - | 5e-07 | 41.54% (65) | patatin |
| M. smegmatis MC2 155 | MSMEG_5284 | - | 2e-06 | 37.14% (70) | patatin |
| M. thermoresistible (build 8) | TH_0679 | - | 4e-07 | 36.92% (65) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0218 | - | 1e-05 | 32.86% (70) | hypothetical protein MUL_0218 |
| M. vanbaalenii PYR-1 | Mvan_4687 | - | 3e-06 | 34.29% (70) | patatin |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5284|M.smegmatis_MC2_155 --------------------------------------------------
TH_0679|M.thermoresistible__bu --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1190|M.avium_104 --------------------------------------------------
MUL_0218|M.ulcerans_Agy99 --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997 --------------------------------------------------
Rv3091|M.tuberculosis_H37Rv MPIPFADGMLSRLGRRGAALDLIEEFEDESGEPPASLSPADLLAAEPALL
Mb3118|M.bovis_AF2122/97 MPIPFADGMLSRLGRRGAALDLIEEFEDESGEPPASLSPADLLAAEPALL
MMAR_1571|M.marinum_M MHIPFAELIGSRFARRHAALDLVDKIDAETQDIDDSLDTVDLPSAEPAQL
MSMEG_5284|M.smegmatis_MC2_155 --------------------------------------------------
TH_0679|M.thermoresistible__bu --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1190|M.avium_104 --------------------------------------------------
MUL_0218|M.ulcerans_Agy99 --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997 --------------------------------------------------
Rv3091|M.tuberculosis_H37Rv LQKMENRLVRHHLANPDVLSGEQLRKLRYILNFARLADFEPGAAGPGGSR
Mb3118|M.bovis_AF2122/97 LQKMENRLVRHHLANPDVLSGEQLRKLRYILNFARLADFEPGAAGPGGSR
MMAR_1571|M.marinum_M LQKMESRLIRQHLANPGVLSDEELRKLRYILNFARLADFEPGAAGPGGSR
MSMEG_5284|M.smegmatis_MC2_155 --------------------------------------------------
TH_0679|M.thermoresistible__bu --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1190|M.avium_104 --------------------------------------------------
MUL_0218|M.ulcerans_Agy99 --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997 --------------------------------------------------
Rv3091|M.tuberculosis_H37Rv GRGDISVGGQVAPWRSRVVDALYAPLREEPDPVTALEGAKDVLATLVDDQ
Mb3118|M.bovis_AF2122/97 GRGDISVGGQVAPWRSRVVDALYAPLREEPDPVTALEGAKDVLATLVDDQ
MMAR_1571|M.marinum_M GRGDISVGAEVAPWRSRVSDTLYGPLREEPDPITALKAARTALDGLSADQ
MSMEG_5284|M.smegmatis_MC2_155 --------------------MTHNESMRVALALGSGSARGYAHIGVINEL
TH_0679|M.thermoresistible__bu ----------------------------VALALGSGGARGYAHIGVIEEL
Mflv_2030|M.gilvum_PYR-GCK --------------------------MRVALALGSGGARGYAHIGVLNEL
Mvan_4687|M.vanbaalenii_PYR-1 --------------------------MRVALALGSGGARGYAHIGVLNEL
MAV_1190|M.avium_104 ----------------------------MALALGSGGARGYAHIGVIEAL
MUL_0218|M.ulcerans_Agy99 ------------MTGPIAVRTHGSSSTRVALALGSGGARGYAHIGVIEAL
MAB_4751|M.abscessus_ATCC_1997 ---------------MTGEASTGVPGTKIALALGAGGARGYAHIGVIQEL
Rv3091|M.tuberculosis_H37Rv DDQRRVLIERHGSDFSATELDAEVGYKKLVTVLGGGGGAGFVYIGGMQRL
Mb3118|M.bovis_AF2122/97 DDQRRVLIERHGSDFSATELDAEVGYKKLVTVLGGGGGAGFVYIGGMQRL
MMAR_1571|M.marinum_M DDQRRVLIERHGSDFSAAELDSEVGYKKLVTILGGGGGAGFVYIGGIQRL
:. **.*.. *:.:** :: *
MSMEG_5284|M.smegmatis_MC2_155 RARGYEIVGISGSSMGALVGGLYAAGK---LDEFAEWACTLTQRAVLR--
TH_0679|M.thermoresistible__bu RARGHEVVGVSGSSMGALVGGVMAAGK---LDDYAAWARTLTQRSVLR--
Mflv_2030|M.gilvum_PYR-GCK RERGHEVVGIAGSSMGALVGGLEAAGK---TDEFTLWATSLTQRAVLR--
Mvan_4687|M.vanbaalenii_PYR-1 TERGHEVVGIAGSSMGALVGGLQAAGK---LDEYTAWASSLTQRAVLR--
MAV_1190|M.avium_104 QARGYDIVGVAGSSMGALVGGLQAAGR---LDEFAEWAKSLTQRTILR--
MUL_0218|M.ulcerans_Agy99 RERGYEIAGIAGSSMGAVVGGLQAAGR---LGEFSDWAKSLNQRTILR--
MAB_4751|M.abscessus_ATCC_1997 HERGFEISGISGSSMGALVGGLEAAGA---LDEFALWATSLTQRAVLR--
Rv3091|M.tuberculosis_H37Rv LAAGQVPDYMIGSSFGSIIGSLVARELPVPIDEYAEWAKTVSYRAILGPE
Mb3118|M.bovis_AF2122/97 LAAGQVPDYMIGSSFGSIIGSLVARELPVPIDEYAEWAKTVSYRAILGPE
MMAR_1571|M.marinum_M LEAGQTPDYMIGSSFGSIIGSLVARCLPVPIDDYVEWAKTVSYRAILGPE
* : ***:*:::*.: * .:: ** ::. *::*
MSMEG_5284|M.smegmatis_MC2_155 --LLDPSLSAAGILRAEKILDAVRDILG--DVTIEELPIPYTAVAT----
TH_0679|M.thermoresistible__bu --LLDPSLTAPGVLRAEKILDAVREILG--EATIETLPIPFTAVAT----
Mflv_2030|M.gilvum_PYR-GCK --LLDPSISSPGVLRAEKILESVRDILG--EVTIEDLPIPYTSVAT----
Mvan_4687|M.vanbaalenii_PYR-1 --LLDPSITSAGVLRAEKILDAVRAIVG--DVTIEELPIPYTAVAT----
MAV_1190|M.avium_104 --LLDPSISAAGVMRAGKILDAVRDILG--PVAIEDLRIPYTAVAT----
MUL_0218|M.ulcerans_Agy99 --LLDPSITAAGVLRAEKILDAVRDILG--PVTIEQLPVPYTAVAT----
MAB_4751|M.abscessus_ATCC_1997 --LLDPTWTSPGFFRAEKILDVVRELLG--DVAIEDLPIPFTAVAT----
Rv3091|M.tuberculosis_H37Rv RRRSRHGLAGMFTLRFDQFAHTLLSRADGERMRMSDLAIPFDVVVAGVRR
Mb3118|M.bovis_AF2122/97 RRRSRHGLAGMFTLRFDQFAHTLLSRADGERMRMSDLAIPFDVVVAGVRR
MMAR_1571|M.marinum_M RLRRRHGLAGMFALRFDQFALSLLSREDNIRLRMSDLTIPFDVVVSGVRK
:. :* :: : . :. * :*: *.:
MSMEG_5284|M.smegmatis_MC2_155 DLITGKAVWLQRGRVDTAIRASIAIPGVIAPHVHDGRLLGDGGILDPLPM
TH_0679|M.thermoresistible__bu DLIAGKSVWLQRGPVDGAIRASIAIPGVIAPHVLDGRLLADGGILDPVPM
Mflv_2030|M.gilvum_PYR-GCK DLITGKSVWMQRGRVDDAIRASIAIPGLITPHVLGGRLLADGGILDPLPM
Mvan_4687|M.vanbaalenii_PYR-1 DLITGKSVWMQRGPLDDAIRASIAIPGVITPYVLDGRLLADGGILDPLPM
MAV_1190|M.avium_104 DLLAGKSVWFQRGPLDEAIRASIAIPGVIAPHTLDGRLLADGGILDPLPM
MUL_0218|M.ulcerans_Agy99 DILAGKSVWFQRGPLDEAIHASIAIPGIIAPHEVDGRLLADGGILDPLPM
MAB_4751|M.abscessus_ATCC_1997 DLIAGKSVWLQNGSLASAIRASIAIPGMISPHVLNGRVLADGGVLDLPAV
Rv3091|M.tuberculosis_H37Rv QPYAALPSRFRHRERSTLTLRSLPFLPIGIGPWVAARMWQVAAFIDLRVV
Mb3118|M.bovis_AF2122/97 QPYAALPSRFRHRERSTLTLRSLPFLPIGIGPWVAARMWQVAAFIDLRVV
MMAR_1571|M.marinum_M QPYSALPSRFRRPELAALQLRSLPFQPIGIGPLVAARMWQVSAFIDLRVV
: :. . ::. *:.: : .*: ...:* :
MSMEG_5284|M.smegmatis_MC2_155 APIASVNADLTIAVSVSGSETPPETASEAHSEPAE-GGGTKPTTEWLNRM
TH_0679|M.thermoresistible__bu APIAAVNADVTIAVSLAGSEAG-------GAEPADRGAGARPTAEWVN--
Mflv_2030|M.gilvum_PYR-GCK APIAAAPADITIAVSLSGEDPA---------VDRRMQDLRQPTTDWLSRM
Mvan_4687|M.vanbaalenii_PYR-1 APIAAVAADMTIAVSISGDDPE---------ASGRGRESRAPSTDWLNRM
MAV_1190|M.avium_104 APLSAVNADLTIAVNLSGSEAI---------TRREAEP--AATAEWLTRM
MUL_0218|M.ulcerans_Agy99 APIAGVNADLTIAVSLNGSESG---------PSRESEP--GVTTEWLNRM
MAB_4751|M.abscessus_ATCC_1997 APLAGVHAELRVAVTLSGGDER---RAPAPPEPEPEPREPRVTTEWLNRL
Rv3091|M.tuberculosis_H37Rv KPIVISADGATRDVNVVDAASFS-SAIPGVLHHETSDPRMLPILDELCAD
Mb3118|M.bovis_AF2122/97 KPIVISADGATRDVNVVDAASFS-SAIPGVLHHETSDPRMLPILDELCAD
MMAR_1571|M.marinum_M KPIVVSGDDPDRDFDVVDAASFS-SAVPGVLHHETSDDRMLDMLDALCAD
*: . : . : :
MSMEG_5284|M.smegmatis_MC2_155 MRSTSAVLDTAAVRSVLDRPTSRAVLSRFGVSVTESD-DGTDASE-----
TH_0679|M.thermoresistible__bu -RLTAALLDSAAARTVRDR---------FGSGAAPADPDPVDQDR-----
Mflv_2030|M.gilvum_PYR-GCK WRSSSSLLDTKAARSLLETPTGRAVLGRFVAADDEPIDAPPE--------
Mvan_4687|M.vanbaalenii_PYR-1 WRSSSSLLDTKAARSLLDTPTGRAVLGRFAAGDDEPLPEPDD--------
MAV_1190|M.avium_104 MRSTSALFDTAAARSLLDRPTARAVLSRLGGPSGDADAWPDNPEEPDQ--
MUL_0218|M.ulcerans_Agy99 VRTTSSIFDATAARSLLDRPT-RAVLNRFGAGSPDQDSWPED-AQIEA--
MAB_4751|M.abscessus_ATCC_1997 LRSTSALFSTDDPE------------------------------------
Rv3091|M.tuberculosis_H37Rv QDVAAMVDGGAASNVPVELAWERVRDGRLGTRNACYLAFDCFHPHWDPRH
Mb3118|M.bovis_AF2122/97 QDVAAMVDGGAASNVPVELAWERVRDGRLGTRNACYLAFDCFHPHWDPRH
MMAR_1571|M.marinum_M QDIAAIVDGGAASNVPVELAWKRVRDGKLGTRNACYLAFDCFHPQWDSRH
:: : . .
MSMEG_5284|M.smegmatis_MC2_155 --DATVPES-----SAEPAGVPRLGSFEVMYRTIDIAQAALARHTLAAYP
TH_0679|M.thermoresistible__bu --ELEEAAE-----NSRSITVPRLGSFEVMNRTIDIAQAALARHTLAAYP
Mflv_2030|M.gilvum_PYR-GCK --VVKHDSA----DATGVPELPRLGSFEVMNRVIDIAQSALARHTLAAYP
Mvan_4687|M.vanbaalenii_PYR-1 --KVTEEPG----NAG----IPKLGAFEVMNRVIDIAQAALARHTLAAYP
MAV_1190|M.avium_104 -PVLADDDDEAVELPGAATDVPKLGSFEVMNRTIDIAQAALARHTLAVYP
MUL_0218|M.ulcerans_Agy99 -PVPERDDG------GYTPGLPKMGSFEVMNRTIDIAQSALARHTLAAYP
MAB_4751|M.abscessus_ATCC_1997 --VAGQPDP-----------AAKLTSFEVMNRTIEVMQSQLARMQLAAHP
Rv3091|M.tuberculosis_H37Rv LWLVPITQAVQLQMVRNLPYADHLVRFEPTLSPVNLAPSAAAIDRACRWG
Mb3118|M.bovis_AF2122/97 LWLVPITQAVQLQMVRNLPYADHLVRFEPTLSPVNLAPSAAAIDRACRWG
MMAR_1571|M.marinum_M MWLAPITQAIQLQMVRNLPYADHLVRFQPTLSPINLAPSAGAIDRAYEWG
:: *: ::: : *
MSMEG_5284|M.smegmatis_MC2_155 ---PDLLIEVPRTVCRSLEFNRAAEVIETGRRLAAEALDS----------
TH_0679|M.thermoresistible__bu ---PDVVIEIPRSVCRSLDFHRAAEVIDAGRELAAAALDDAGLT------
Mflv_2030|M.gilvum_PYR-GCK ---PDLLIEVPRTVCRSLDFHRAHEVIEIGQELASAALEALDPEPSEA--
Mvan_4687|M.vanbaalenii_PYR-1 ---PDLLIEVPRTVCRSLDFHRATEVIEIGQELASAALDTLEQKVPETAS
MAV_1190|M.avium_104 ---PDLLIEVPRSICRGLEFHRAVEVIDAGRALADQALDALEDGDD-DRP
MUL_0218|M.ulcerans_Agy99 ---ADLLIEVPRSTCRSLEFHRASEVIAVGRALANRALDALESADQPATP
MAB_4751|M.abscessus_ATCC_1997 ---PDVLIEVPRSVSRSLDFHRATEVIEVGRRCAAEALDAYAHTN-----
Rv3091|M.tuberculosis_H37Rv RDSVEPAIAVTSALLEPTWWEGDRPPAAEPKERTKSAASSMSAVMAAIQA
Mb3118|M.bovis_AF2122/97 RDSVEPAIAVTSALLEPTWWEGDRPPAAEPKERTKSAASSMSAVMAAIQA
MMAR_1571|M.marinum_M RSSVEDAIPVTTALLRPTWWEGDGPPVAEPAEHASSVASSMSSVMAAIHA
: * :. : . :. : . .
MSMEG_5284|M.smegmatis_MC2_155 --------------
TH_0679|M.thermoresistible__bu --------------
Mflv_2030|M.gilvum_PYR-GCK --------------
Mvan_4687|M.vanbaalenii_PYR-1 DT------------
MAV_1190|M.avium_104 AVER----------
MUL_0218|M.ulcerans_Agy99 AIEG----------
MAB_4751|M.abscessus_ATCC_1997 --------------
Rv3091|M.tuberculosis_H37Rv PTGRFRRWRSRHLT
Mb3118|M.bovis_AF2122/97 PTGRFRRWRSRHLT
MMAR_1571|M.marinum_M PTGRFARWRDRHLT